100-72-1 | Tetrahydropyran-2-methanol

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$13.00	$9.00
5g	98%	in stock	$27.00	$19.00
25g	98%	in stock	$89.00	$63.00
100g	98%	in stock	$334.00	$234.00

Description

• Catalog Number: AA00046
• Chemical Name: Tetrahydropyran-2-methanol
• CAS Number: 100-72-1
• Molecular Formula: C6H12O2
• Molecular Weight: 116.15827999999998
• MDL Number: MFCD00006624
• SMILES: OCC1CCCCO1

Computed Properties

• Complexity: 63.5
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• Undefined Atom Stereocenter Count: 1
• XLogP3: 0.3

Upstream Synthesis Route

(Tetrahydro-2H-pyran-2-yl)methanol, more commonly referred to as THP-methanol, is a valuable compound used extensively in chemical synthesis. This versatile building block is renowned for its ability to serve as a protective group for alcohols in organic reactions. By temporarily masking the hydroxyl functional group with the THP moiety, chemists can selectively manipulate other parts of the molecule without affecting the alcohol functionality, thereby enabling precise control over regioselectivity and stereochemistry during complex synthesis processes. THP-methanol finds particular utility in the synthesis of pharmaceuticals, natural products, and fine chemicals where precise molecular architecture is essential for achieving desired biological or physical properties. Its strategic incorporation in synthetic pathways facilitates the formation of intricate molecular structures with high efficiency and selectivity, making it an indispensable tool in the arsenal of synthetic chemists striving to access novel compounds for various applications.