100-82-3 | 3-Fluorobenzylamine

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$15.00	$11.00
5g	97%	in stock	$34.00	$24.00
25g	97%	in stock	$66.00	$47.00
100g	97%	in stock	$183.00	$129.00
500g	97%	in stock	$853.00	$597.00

Description

• Catalog Number: AA00085
• Chemical Name: 3-Fluorobenzylamine
• CAS Number: 100-82-3
• Molecular Formula: C7H8FN
• Molecular Weight: 125.1435
• MDL Number: MFCD00008113
• SMILES: NCc1cccc(c1)F

Computed Properties

• Complexity: 85
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 1.2

Upstream Synthesis Route

3-Fluorobenzylamine, also known as 3-aminofluorobenzene, is a valuable chemical building block widely used in organic synthesis. Its unique structure, featuring a fluorine atom attached to the benzene ring along with an amino group at the para position, confers specific properties that make it a versatile reagent in a variety of chemical reactions.One of the key applications of 3-Fluorobenzylamine in chemical synthesis is its use as a starting material for the preparation of various pharmaceutical compounds and agrochemicals. The presence of the amino group allows for functional group transformations through a range of synthetic methods, enabling the incorporation of this moiety into complex molecular structures. Additionally, the fluorine atom imparts beneficial properties such as increased metabolic stability and altered chemical reactivity in the final products.Furthermore, 3-Fluorobenzylamine can serve as a key intermediate in the synthesis of fluorinated aromatic compounds, which are of interest in medicinal chemistry due to their unique biological activities and improved pharmacokinetic profiles. Its versatile reactivity enables the introduction of fluorine-containing motifs into organic molecules, leading to the development of novel drug candidates with enhanced properties.In summary, 3-Fluorobenzylamine plays a crucial role in chemical synthesis by serving as a valuable building block for the construction of diverse molecular architectures with applications ranging from pharmaceuticals to materials science. Its distinct structural features make it a sought-after reagent in the development of novel compounds with enhanced properties and potential therapeutic benefits.

Literature

• Benzylamines: synthesis and evaluation of antimycobacterial properties.

  Journal of medicinal chemistry 19840901