100-86-7 | 2-Methyl-1-phenyl-2-propanol

Packsize	Purity	Availability	Price	Discounted Price
25g	95%	in stock	$7.00	$5.00
100g	95%	in stock	$23.00	$16.00
500g	95%	in stock	$63.00	$45.00
1000g	95%	in stock	$76.00	$53.00

Description

• Catalog Number: AB62575
• Chemical Name: 2-Methyl-1-phenyl-2-propanol
• CAS Number: 100-86-7
• Molecular Formula: C10H14O
• Molecular Weight: 150.2176
• MDL Number: MFCD00004465
• SMILES: CC(Cc1ccccc1)(O)C

Computed Properties

• Complexity: 112
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• XLogP3: 2.2

Upstream Synthesis Route

2-Methyl-1-phenyl-2-propanol, also known as α-Methylbenzyl alcohol, plays a crucial role in chemical synthesis as a versatile building block. Due to its unique structure, this compound is widely utilized in organic chemistry for the preparation of various pharmaceuticals, fragrances, and specialty chemicals. Its primary application lies in its ability to serve as a key intermediate in the synthesis of complex organic molecules.In chemical reactions, 2-Methyl-1-phenyl-2-propanol can act as both a nucleophile and an electrophile, making it a valuable reagent in diverse synthetic transformations. It can undergo various functional group manipulations, such as oxidation, reduction, and substitution reactions, to introduce new functionalities into the molecular structure. Moreover, its chiral center allows for the creation of enantiomerically pure compounds, which is essential in drug development and asymmetric synthesis.Additionally, 2-Methyl-1-phenyl-2-propanol is employed as a protective group in organic synthesis to temporarily shield reactive functionalities, thereby enabling selective reactions at specific sites within a molecule. This protective strategy enhances the efficiency and precision of multi-step synthetic pathways, leading to higher product yields and purities. Overall, the versatility and reactivity of 2-Methyl-1-phenyl-2-propanol make it a valuable asset in the toolbox of synthetic chemists for the construction of complex organic molecules.

Literature

• Fragrance material review on α,α-dimethylphenethyl alcohol.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120901

• Chemoenzymatic synthesis of optically active, biodegradable polymers based on phenyl- and naphthyl-ethanols esterified with divinyladipate.

  Biotechnology letters 20040401