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Home  > 4-Bromo-6-(trifluoromethyl)-1h-indazole

AA00515

1000342-95-9 | 4-Bromo-6-(trifluoromethyl)-1h-indazole

Packsize Purity Availability Price Discounted Price    Quantity
50mg 97% in stock $19.00 $13.00 -   +
250mg 97% in stock $20.00 $14.00 -   +
1g 97% in stock $45.00 $32.00 -   +
5g 97% in stock $195.00 $137.00 -   +
10g 97% in stock $376.00 $264.00 -   +

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*All prices are in USD.

Description
Catalog Number: AA00515
Chemical Name: 4-Bromo-6-(trifluoromethyl)-1h-indazole
CAS Number: 1000342-95-9
Molecular Formula: C8H4BrF3N2
Molecular Weight: 265.03
MDL Number: MFCD09026956
SMILES: Brc1cc(cc2c1cn[nH]2)C(F)(F)F

 

Upstream Synthesis Route
  • 4-Bromo-6-(trifluoromethyl)-1H-indazole is a valuable compound in chemical synthesis due to its versatile applications in the field of organic chemistry. This indazole derivative is commonly utilized as a key building block for the synthesis of complex organic molecules, including pharmaceuticals, agrochemicals, and materials. Its unique chemical structure, incorporating both a bromine atom and a trifluoromethyl group, imparts distinct reactivity and properties that make it a highly sought-after reagent.In chemical synthesis, 4-Bromo-6-(trifluoromethyl)-1H-indazole serves as a valuable starting material for the preparation of various heterocyclic compounds through functional group transformations and multi-step synthetic routes. The presence of the bromine atom allows for selective derivatization at this position, enabling the introduction of diverse functional groups for further elaboration. Additionally, the trifluoromethyl group enhances the electron density and lipophilicity of the molecule, influencing its behavior in reactions and biological activity.Furthermore, 4-Bromo-6-(trifluoromethyl)-1H-indazole can participate in transition metal-catalyzed cross-coupling reactions, such as Suzuki-Miyaura and Sonogashira couplings, to construct aryl-aryl and aryl-alkenyl bonds. These transformations enable the rapid assembly of complex molecular frameworks with high efficiency and selectivity. Overall, the strategic incorporation of this indazole derivative in chemical synthesis allows for the streamlined access to structurally diverse and biologically relevant molecules with potential applications in drug discovery and materials science.
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