1000386-63-9 | 4-fluoro-1-methoxy-2-naphthoic acid

Availability
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Description

• Catalog Number: BI25005
• Chemical Name: 4-fluoro-1-methoxy-2-naphthoic acid
• CAS Number: 1000386-63-9
• Molecular Formula: C12H9FO3
• Molecular Weight: 220.1965
• MDL Number: MFCD28952815
• SMILES: COc1c(cc(c2c1cccc2)F)C(=O)O

Upstream Synthesis Route

4-Fluoro-1-methoxy-2-naphthoic acid is a versatile compound widely utilized in chemical synthesis processes. This compound serves as a key building block in the creation of various organic molecules due to its unique structure and reactivity. Its specific applications include:1. **Fluorination Reactions:** The presence of a fluorine atom in the aromatic ring of 4-fluoro-1-methoxy-2-naphthoic acid makes it a valuable precursor in fluorination reactions. This compound can be used to introduce fluorine atoms into organic molecules, imparting specific properties or enhancing biological activity.2. **Cross-Coupling Reactions:** 4-Fluoro-1-methoxy-2-naphthoic acid can participate in cross-coupling reactions, such as Suzuki-Miyaura or Heck reactions, to form carbon-carbon or carbon-heteroatom bonds. These transformations are essential in the construction of complex organic frameworks found in pharmaceuticals, agrochemicals, and materials science.3. **Medicinal Chemistry:** The functional groups present in 4-fluoro-1-methoxy-2-naphthoic acid make it a valuable intermediate in the synthesis of pharmaceutical compounds. By incorporating this building block into drug molecules, chemists can modulate their physicochemical properties, enhance bioavailability, or improve target specificity.4. **Materials Science:** The aromatic nature of 4-fluoro-1-methoxy-2-naphthoic acid lends itself to applications in materials science. This compound can be incorporated into polymers, liquid crystals, or other advanced materials to tailor their properties, such as thermal stability, fluorescence, or optical behavior.Overall, the strategic placement of fluorine and methoxy groups in 4-fluoro-1-methoxy-2-naphthoic acid makes it a valuable asset in chemical synthesis, enabling the construction of diverse organic compounds with relevance in medicinal chemistry, materials science, and other fields.