1000577-24-1 | 2-Bromo-3,4,5-trifluoroaniline

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$15.00	$10.00
1g	95%	in stock	$16.00	$11.00
5g	95%	in stock	$23.00	$17.00
25g	95%	in stock	$63.00	$45.00

Description

• Catalog Number: AA00764
• Chemical Name: 2-Bromo-3,4,5-trifluoroaniline
• CAS Number: 1000577-24-1
• Molecular Formula: C6H3BrF3N
• Molecular Weight: 225.9939
• MDL Number: MFCD01311010
• SMILES: Fc1cc(N)c(c(c1F)F)Br

Computed Properties

• Complexity: 146
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• XLogP3: 2.2

Upstream Synthesis Route

2-Bromo-3,4,5-trifluoroaniline is a key reagent in chemical synthesis, particularly in the field of medicinal chemistry and materials science. This compound serves as a versatile building block for the production of various pharmaceuticals, agrochemicals, and functional materials.In chemical synthesis, 2-Bromo-3,4,5-trifluoroaniline is commonly used as a precursor for the synthesis of complex organic molecules due to its unique fluorine and bromine substituents. These substituents enable various synthetic transformations, such as nucleophilic substitution reactions, palladium-catalyzed cross-coupling reactions, and halogenation reactions.One of the important applications of 2-Bromo-3,4,5-trifluoroaniline is in the synthesis of fluorinated pharmaceuticals. The incorporation of trifluoromethyl and bromine groups in drug molecules can significantly enhance their biological activities, metabolic stability, and lipophilicity. This compound can be utilized to introduce fluorine atoms into drug candidates, thereby improving their pharmacokinetic properties and therapeutic potential.Furthermore, 2-Bromo-3,4,5-trifluoroaniline plays a crucial role in the development of functional materials, such as liquid crystals, polymers, and organic electronic devices. By incorporating this compound into the molecular structure of these materials, researchers can tailor their physical properties, such as optical properties, thermal stability, and electron affinity.Overall, the versatile applications of 2-Bromo-3,4,5-trifluoroaniline in chemical synthesis highlight its significance as a valuable building block for the construction of diverse organic molecules and functional materials.