1002344-97-9 | 4-Chloro-2-fluoro-3-methoxybenzaldehyde

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$74.00	$52.00
5g	97%	in stock	$230.00	$161.00
10g	97%	in stock	$368.00	$258.00
25g	97%	in stock	$837.00	$586.00

Description

• Catalog Number: AA01515
• Chemical Name: 4-Chloro-2-fluoro-3-methoxybenzaldehyde
• CAS Number: 1002344-97-9
• Molecular Formula: C8H6ClFO2
• Molecular Weight: 188.5834
• MDL Number: MFCD19687172
• SMILES: COc1c(Cl)ccc(c1F)C=O

Computed Properties

• Complexity: 165
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• XLogP3: 2.1

Upstream Synthesis Route

4-Chloro-2-fluoro-3-methoxybenzaldehyde (CFMBA) is a versatile chemical compound widely used in chemical synthesis. In organic chemistry, CFMBA serves as a key intermediate in the synthesis of various pharmaceuticals, agrochemicals, and fine chemicals. Due to its unique structure and reactivity, CFMBA is particularly valuable in the preparation of complex molecules with specific biological activities.One common application of 4-Chloro-2-fluoro-3-methoxybenzaldehyde is in the synthesis of heterocyclic compounds. By utilizing CFMBA as a starting material, chemists can easily access a range of functionalized benzofuran, benzothiophene, and benzoxazole derivatives. These heterocycles are essential components of many biologically active compounds, making CFMBA a crucial building block in medicinal chemistry.Additionally, 4-Chloro-2-fluoro-3-methoxybenzaldehyde is utilized in the synthesis of fluorinated aromatic compounds. The incorporation of fluorine atoms into organic molecules can significantly alter their physical and chemical properties, leading to compounds with enhanced pharmacokinetic profiles and improved biological activities. CFMBA's ability to introduce a fluoro substituent makes it a valuable tool for the preparation of fluorinated drug candidates and agrochemicals.Overall, the strategic placement of the chloro, fluoro, and methoxy groups in CFMBA imparts valuable synthetic versatility, allowing chemists to access diverse molecular scaffolds for various applications in chemical synthesis. By leveraging the unique reactivity of 4-Chloro-2-fluoro-3-methoxybenzaldehyde, researchers can expedite the synthesis of complex molecules with enhanced biological activities and tailored functionalities.