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Copper(I) (pseudo)halide complexes with neocuproine and aminomethylphosphines derived from morpholine and thiomorpholine - in vitro cytotoxic and antimicrobial activity and the interactions with DNA and serum albumins.
Chemical biology & drug design 20131101
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A mechanistic and kinetic study on the decomposition of morpholine.
The journal of physical chemistry. A 20120726
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Haloenol pyranones and morpholinones as antineoplastic agents of prostate cancer.
Bioorganic & medicinal chemistry letters 20120715
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Touch responsiveness in zebrafish requires voltage-gated calcium channel 2.1b.
Journal of neurophysiology 20120701
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A convenient route to optically pure α-alkyl-β-(sec-amino)alanines.
Amino acids 20120601
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2-Morpholinoisoflav-3-enes as flexible intermediates in the synthesis of phenoxodiol, isophenoxodiol, equol and analogues: vasorelaxant properties, estrogen receptor binding and Rho/RhoA kinase pathway inhibition.
Bioorganic & medicinal chemistry 20120401
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Ultra-trace level analysis of morpholine, cyclohexylamine, and diethylaminoethanol in steam condensate by gas chromatography with multi-mode inlet, and flame ionization detection.
Journal of chromatography. A 20120316
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Metabolism and pharmacokinetics of morinidazole in humans: identification of diastereoisomeric morpholine N+-glucuronides catalyzed by UDP glucuronosyltransferase 1A9.
Drug metabolism and disposition: the biological fate of chemicals 20120301
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Shedding light by cancer redox-human NAD(P)H:quinone oxidoreductase 1 activation of a cloaked fluorescent dye.
Chemical communications (Cambridge, England) 20111028
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Ceric ammonium nitrate-catalyzed azidation of 1,2-anhydro sugars: application in the synthesis of structurally diverse sugar-derived morpholine 1,2,3-triazoles and 1,4-oxazin-2-ones.
The Journal of organic chemistry 20110805
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Morpholine catalyzed direct C3 alkenylation of indoles with α,β-unsaturated aldehydes.
Chemical communications (Cambridge, England) 20110728
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Synthesis, structural elucidation, DNA-PK inhibition, homology modelling and anti-platelet activity of morpholino-substituted-1,3-naphth-oxazines.
Bioorganic & medicinal chemistry 20110701
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Nickel-catalyzed amination of aryl sulfamates.
Angewandte Chemie (International ed. in English) 20110225
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Unexpected side products in the conjugation of an amine-derivatized morpholino oligomer with p-isothiocyanate benzyl DTPA and their removal.
Nuclear medicine and biology 20110201
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Analyses of gene function in amphioxus embryos by microinjection of mRNAs and morpholino oligonucleotides.
Methods in molecular biology (Clifton, N.J.) 20110101
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[Synthesis of 2'-aminometylmorpholino nucleoside analogues containing 4'-carboxymethyl lynker group].
Bioorganicheskaia khimiia 20110101
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Chemical genetics approach to identify new small molecule modulators of cell growth by phenotypic screening of Saccharomyces cerevisiae strains with a library of morpholine-derived compounds.
Organic & biomolecular chemistry 20101221
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A nanochannel array-based electrochemical device for quantitative label-free DNA analysis.
ACS nano 20101123
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Synthesis of enantiopure 3-substituted morpholines.
The Journal of organic chemistry 20101105
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Design of more potent squalene synthase inhibitors with multiple activities.
Bioorganic & medicinal chemistry 20101101
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Chalcogenides of the aminomethylphosphines derived from 1-methylpiperazine, 1-ethylpiperazine and morpholine: NMR, DFT and structural studies for determination of electronic and steric properties of the phosphines.
Dalton transactions (Cambridge, England : 2003) 20100828
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Synthesis, electrochemical studies and anticancer activity of ferrocenyl oxindoles.
Dalton transactions (Cambridge, England : 2003) 20100821
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Identification of microRNA-93 as a novel regulator of vascular endothelial growth factor in hyperglycemic conditions.
The Journal of biological chemistry 20100723
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Acortatarins A and B, two novel antioxidative spiroalkaloids with a naturally unusual morpholine motif from Acorus tatarinowii.
Organic letters 20100416
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Total regioselective transformation of aromatic aziridine 2-carboxamides into 2-aminoamides promoted by active manganese.
The Journal of organic chemistry 20100402
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Development of an in vitro system combining aqueous and lipid phases as a tool to understand gastric nitrosation.
Rapid communications in mass spectrometry : RCM 20100315
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Evaluation of stereochemically dense morpholine-based scaffolds as proline surrogates in beta-turn peptides.
Organic & biomolecular chemistry 20100221
-
One-pot synthesis of 1,3-disubstituted allenes from 1-alkynes, aldehydes, and morpholine.
Journal of the American Chemical Society 20100217
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Synthesis, structural characterization and antiproliferative and toxic bio-activities of copper(II) and nickel(II) citronellal N4-ethylmorpholine thiosemicarbazonates.
Journal of inorganic biochemistry 20100201
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Spectroscopic characterization of charge-transfer complexes of morpholine with chloranilic and picric acids in organic media: crystal structure of bis(morpholinium 2,4,6-trinitrocyclohexanolate).
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100201
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Modular synthesis and in vitro and in vivo antimalarial assessment of C-10 pyrrole mannich base derivatives of artemisinin.
Journal of medicinal chemistry 20100128
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Discovery of 3,6-dihydro-2H-pyran as a morpholine replacement in 6-aryl-1H-pyrazolo[3,4-d]pyrimidines and 2-arylthieno[3,2-d]pyrimidines: ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR).
Bioorganic & medicinal chemistry letters 20100115
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Catalytic SNAr reaction of non-activated fluoroarenes with amines via Ru eta6-arene complexes.
Chemical communications (Cambridge, England) 20100114
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Discovery of 2-arylthieno[3,2-d]pyrimidines containing 8-oxa-3-azabi-cyclo[3.2.1]octane in the 4-position as potent inhibitors of mTOR with selectivity over PI3K.
Bioorganic & medicinal chemistry letters 20100101
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Novel orally active morpholine N-arylsulfonamides gamma-secretase inhibitors with low CYP 3A4 liability.
Bioorganic & medicinal chemistry letters 20091101
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Novel 4-(morpholin-4-yl)-N'-(arylidene)benzohydrazides: synthesis, antimycobacterial activity and QSAR investigations.
European journal of medicinal chemistry 20091001
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Malonyl-CoA decarboxylase inhibition is selectively cytotoxic to human breast cancer cells.
Oncogene 20090820
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Muscarinic receptor 1 agonist activity of novel N-aryl carboxamide substituted 3-morpholino arecoline derivatives in Alzheimer's presenile dementia models.
Bioorganic & medicinal chemistry 20090801
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Synthesis of some new 1,3,4-thiadiazol-2-ylmethyl-1,2,4-triazole derivatives and investigation of their antimicrobial activities.
European journal of medicinal chemistry 20090701
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Exploring the PI3K alpha and gamma binding sites with 2,6-disubstituted isonicotinic derivatives.
Bioorganic & medicinal chemistry letters 20090415
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Morpholine containing CB2 selective agonists.
Bioorganic & medicinal chemistry letters 20090315
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Morpholine-based RGD-cyclopentapeptides as alphavbeta3/alphavbeta5 integrin ligands: role of configuration towards receptor binding affinity.
Bioorganic & medicinal chemistry 20090215
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The effect of bacterial glutathione S-transferase on morpholine degradation.
Biotechnology journal 20090201
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Practical synthesis of a p38 MAP kinase inhibitor.
The Journal of organic chemistry 20090116
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Synthesis and structure-activity studies of novel homomorpholine oxazolidinone antibacterial agents.
Bioorganic & medicinal chemistry letters 20090115
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Bromoethylsulfonium salt--a more effective annulation agent for the synthesis of 6- and 7-membered 1,4-heterocyclic compounds.
Organic letters 20090115
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Intercalating, cytotoxic, antitumour activity of 8-chloro and 4-morpholinopyrimido [4',5':4,5]thieno(2,3-b)quinolines.
Journal of photochemistry and photobiology. B, Biology 20090109
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Quantum chemical studies for oxidation of morpholine by Cytochrome P450.
Journal of inorganic biochemistry 20090101
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Zebrafish dorsal root ganglia neural precursor cells adopt a glial fate in the absence of neurogenin1.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20081119
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Chromatographic behavior of zwitterionic enalapril-exploring the conditions for lipophilicity assessment.
Journal of pharmaceutical and biomedical analysis 20081104
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Design and synthesis of reboxetine analogs morpholine derivatives as selective norepinephrine reuptake inhibitors.
Bioorganic & medicinal chemistry letters 20081015
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Stereoselective cyclopropanation of serine- and threonine-derived oxazines to access new morpholine-based scaffolds.
Organic & biomolecular chemistry 20080921
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Development of a practical Buchwald-Hartwig amine arylation protocol using a conveniently prepared (NHC)Pd(R-allyl)Cl catalyst.
Organic & biomolecular chemistry 20080807
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Design and synthesis of morpholine derivatives. SAR for dual serotonin & noradrenaline reuptake inhibition.
Bioorganic & medicinal chemistry letters 20080415
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Morpholine-based immonium and halogenoamidinium salts as coupling reagents in Peptide synthesis1.
The Journal of organic chemistry 20080404
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New stimuli-responsive polymers derived from morpholine and pyrrolidine.
Journal of materials science. Materials in medicine 20080401
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Sampling and analytical methodology development for the determination of primary and secondary low molecular weight amines in ambient air.
Journal of environmental monitoring : JEM 20080301
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CNS-derived glia ensheath peripheral nerves and mediate motor root development.
Nature neuroscience 20080201
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Evaluation of radioiodinated (2S,alphaS)-2-(alpha-(2-iodophenoxy)benzyl)morpholine as a radioligand for imaging of norepinephrine transporter in the heart.
Nuclear medicine and biology 20080201
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Arachidonic acid as a retrograde signal controlling growth and dynamics of retinotectal arbors.
Developmental neurobiology 20080101
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Isostructural materials achieved by using structurally equivalent donors and acceptors in halogen-bonded cocrystals.
Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
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Spirocyclic oxetanes: synthesis and properties.
Angewandte Chemie (International ed. in English) 20080101
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New oligonucleotide analogues based on morpholine subunits joined by oxalyl diamide tether.
Bioorganic chemistry 20070601
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Convenient route to enantiopure fmoc-protected morpholine-3-carboxylic acid.
The Journal of organic chemistry 20070525
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Spectroscopic and kinetic evidence for an accumulating intermediate in an SNV reaction with amine nucleophiles. Reaction of methyl beta-methylthio-alpha-nitrocinnamate with piperidine and morpholine.
The Journal of organic chemistry 20070427
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Synthesis of novel quinolone and quinoline-2-carboxylic acid (4-morpholin-4-yl-phenyl)amides: a late-stage diversification approach to potent 5HT1B antagonists.
Bioorganic & medicinal chemistry 20070115
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Physiological, biochemical, and genetic characterization of an alicyclic amine-degrading Mycobacterium sp. strain THO100 isolated from a morpholine-containing culture of activated sewage sludge.
Archives of microbiology 20061101
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Rhodococcus sp. strain TM1 plays a synergistic role in the degradation of piperidine by Mycobacterium sp. strain THO100.
Archives of microbiology 20060901
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Asymmetric synthesis of 1-(2- and 3-haloalkyl)azetidin-2-ones as precursors for novel piperazine, morpholine, and 1,4-diazepane annulated beta-lactams.
The Journal of organic chemistry 20060901
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Nyctalopin is essential for synaptic transmission in the cone dominated zebrafish retina.
The European journal of neuroscience 20060901
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Asymmetric synthesis of enantioenriched (+)-elaeokanine A.
The Journal of organic chemistry 20060721
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Photoaddition of N-substituted piperazines to C60: an efficient approach to the synthesis of water-soluble fullerene derivatives.
Chemistry (Weinheim an der Bergstrasse, Germany) 20060717
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Palladium-catalyzed intermolecular alpha-arylation of zinc amide enolates under mild conditions.
Journal of the American Chemical Society 20060419
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PET modulated fluorescent sensing from the BF2 chelated azadipyrromethene platform.
Organic & biomolecular chemistry 20060307
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Comments on the ring-opening polymerization of morpholine-2,5-dione derivatives by various metal catalysts and characterization of the products formed in the reactions involving R2SnX2, where X = OPr(i) and NMe2 and R = Bu(n), Ph and p-Me2NC6H4.
Dalton transactions (Cambridge, England : 2003) 20060214
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Synthesis of new nitrogen analogues of salacinol and deoxynojirimycin and their evaluation as glycosidase inhibitors.
The Journal of organic chemistry 20060203
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Aminolysis of 2,4-dinitrophenyl X-substituted benzoates and Y-substituted phenyl benzoates in MeCN: effect of the reaction medium on rate and mechanism.
Chemistry (Weinheim an der Bergstrasse, Germany) 20060123
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Stress evoked by opiate withdrawal facilitates hippocampal LTP in vivo.
Hippocampus 20060101
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Polarization and orientation of retinal ganglion cells in vivo.
Neural development 20060101
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Kinetic and binding studies with purified recombinant proteins ferredoxin reductase, ferredoxin and cytochrome P450 comprising the morpholine mono-oxygenase from Mycobacterium sp. strain HE5.
The FEBS journal 20050301
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Carbonic anhydrase inhibitors. Novel sulfanilamide/acetazolamide derivatives obtained by the tail approach and their interaction with the cytosolic isozymes I and II, and the tumor-associated isozyme IX.
Bioorganic & medicinal chemistry letters 20050117
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Arginine-rich peptide conjugation to morpholino oligomers: effects on antisense activity and specificity.
Bioconjugate chemistry 20050101
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From hydrocolloids to high specific surface area porous supports for catalysis.
Biomacromolecules 20050101
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Synthesis, enantiomeric resolution, and selective C-11 methylation of a highly selective radioligand for imaging the norepinephrine transporter with positron emission tomography.
Chirality 20040801
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Ruthenium-catalyzed anti-Markovnikov hydroamination of vinylarenes.
Journal of the American Chemical Society 20040310
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Role of aryl hydrocarbon receptor in mesencephalic circulation failure and apoptosis in zebrafish embryos exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Toxicological sciences : an official journal of the Society of Toxicology 20040101
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Molecular cloning, nucleotide sequencing and expression of genes encoding a cytochrome P450 system involved in secondary amine utilization in Mycobacterium sp. strain RP1.
Research in microbiology 20040101
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[Polyfunctional molecules and their components in the processes of aromatic nucleophilic substitution. II. Nucleophilic modification of 3',5'-bis-O-(alpha,beta,alpha',beta'-tetrafluoropyridyl-gamma)thymidine].
Bioorganicheskaia khimiia 20040101
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Interactions of novel morpholine and hexamethylene derivatives of anthracycline antibiotics with DNA.
Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101
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Insights into the origin of high activity and stability of catalysts derived from bulky, electron-rich monophosphinobiaryl ligands in the Pd-catalyzed C-N bond formation.
Journal of the American Chemical Society 20031119
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[Antithrombotic effects of morpholine and piperazine ring derivatives and their molecular mechanism].
Yao xue xue bao = Acta pharmaceutica Sinica 20030901
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Detection of in vivo genotoxicity of endogenously formed N-nitroso compounds and suppression by ascorbic acid, teas and fruit juices.
Mutation research 20030805
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Rhodium-catalyzed anti-Markovnikov hydroamination of vinylarenes.
Journal of the American Chemical Society 20030514
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Determination of the DS and substituent distribution of cationic alkyl polyglycosides and cationic starch ethers by GLC after dealkylation with morpholine.
Carbohydrate research 20030404
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Trichloroacetylation of some cyclic enamines.
Chemical & pharmaceutical bulletin 20030401
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[Research concerning rutin semisynthetic derivatives, synthesis and pharmaco-toxicological properties of some new morpholine and piperidine derivatives].
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20030101
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Enantiopure beta-hydroxy morpholine amides from terminal epoxides by carbonylation at 1 atm.
Angewandte Chemie (International ed. in English) 20021216
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The formation of paracetamol (acetaminophen) adducts with hydrogen-bond acceptors.
Acta crystallographica. Section B, Structural science 20021201
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Natural abundance nitrogen-15 nuclear magnetic resonance spectral studies on selected donors.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20021001
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An amino alcohol ligand for highly enantioselective addition of organozinc reagents to aldehydes: serendipity rules.
Organic letters 20020627
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Helicobacter pylori does not mediate the formation of carcinogenic N-nitrosamines.
Helicobacter 20020601
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Tumor pretargeting in mice using (99m)Tc-labeled morpholino, a DNA analog.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20020301
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[Influence of thyroid hormones on memory imprinting of chemical signals in early development of sturgeon Acipenser gueldenstaedti].
Zhurnal evoliutsionnoi biokhimii i fiziologii 20020101
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A cytochrome P450 and a ferredoxin isolated from Mycobacterium sp. strain HE5 after growth on morpholine.
Applied microbiology and biotechnology 20010801
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Comparison of morpholino based translational inhibition during the development of Xenopus laevis and Xenopus tropicalis.
Genesis (New York, N.Y. : 2000) 20010701
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Determination of morpholine in air by derivatisation with 1-naphthylisothiocyanate and HPLC analysis.
The Analyst 20010201
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Final report on the safety assessment of Cetethyl Morpholinium Ethosulfate.
International journal of toxicology 20010101
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Thiomorpholine and morpholine oxidation by a cytochrome P450 in Mycobacterium aurum MO1. Evidence of the intermediates by in situ 1H NMR.
Biodegradation 19980101
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[Pharmacological studies on yohimbic acid ethyl ester (A 38) and 4-=2-(p-butoxyphenyl)-1,3-dioxolan-2-ylmethyl=-morpholine methobromide (Q 160) as well as the influence of these substances on reserpine action].
Arzneimittel-Forschung 19550801
