1003-09-4 | 2-Bromothiophene

Packsize	Purity	Availability	Price	Discounted Price
25g	98%	in stock	$22.00	$15.00
100g	98%	in stock	$64.00	$45.00
500g	98%	in stock	$136.00	$95.00

Description

• Catalog Number: AA01738
• Chemical Name: 2-Bromothiophene
• CAS Number: 1003-09-4
• Molecular Formula: C4H3BrS
• Molecular Weight: 163.0356
• MDL Number: MFCD00005417
• SMILES: Brc1cccs1
• NSC Number: 4456

Computed Properties

• Complexity: 46.8
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 1
• XLogP3: 2.8

Upstream Synthesis Route

2-Bromothiophene is a valuable building block in chemical synthesis due to its versatile reactivity and unique molecular structure. One prominent application of 2-Bromothiophene is in the synthesis of various pharmaceutical compounds and agrochemicals. Its bromine functional group allows for selective derivatization, enabling the introduction of different substituents to modulate the properties of the final product. Additionally, the thiophene ring provides aromaticity and electron-rich character, which are beneficial for interactions with biological targets or catalytic systems.In organic synthesis, 2-Bromothiophene can serve as a key intermediate for the construction of more complex molecules through coupling reactions such as Suzuki, Heck, or Stille couplings. These transformations enable the formation of carbon-carbon and carbon-heteroatom bonds, expanding the chemical space of potential products.Furthermore, 2-Bromothiophene can be utilized in material science for the preparation of conducting polymers, dyes, and electroactive materials. Its conjugated structure and electronic properties make it suitable for applications in organic electronics, sensors, and optoelectronic devices.Overall, the versatile nature of 2-Bromothiophene makes it a valuable tool for chemists in designing and synthesizing a wide range of compounds with diverse functionalities and applications.

Literature

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  Journal of the American Chemical Society 20111026

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  European journal of medicinal chemistry 20090801

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  Journal of the American Chemical Society 20060823

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  Organic letters 20051027

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  The Journal of organic chemistry 20031031