100342-30-1 | N-tert-Butyl-2-thiophenesulfonamide

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$19.00	$13.00
5g	95%	in stock	$27.00	$19.00
25g	95%	in stock	$82.00	$57.00
100g	95%	in stock	$318.00	$223.00

Description

• Catalog Number: AA01985
• Chemical Name: N-tert-Butyl-2-thiophenesulfonamide
• CAS Number: 100342-30-1
• Molecular Formula: C8H13NO2S2
• Molecular Weight: 219.3243
• MDL Number: MFCD02047252
• SMILES: CC(NS(=O)(=O)c1cccs1)(C)C

Computed Properties

• Complexity: 261
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 3
• XLogP3: 1.1

Upstream Synthesis Route

N-tert-Butyl-2-thiophenesulfonamide is a versatile compound widely used in chemical synthesis as a valuable building block. Due to its unique structure and reactivity, it serves as a crucial intermediate in the preparation of various pharmaceuticals, agrochemicals, and functional materials. This compound is known for its ability to participate in diverse reactions, including nucleophilic substitution, palladium-catalyzed coupling reactions, and various cyclization processes. In the field of organic synthesis, N-tert-Butyl-2-thiophenesulfonamide plays a significant role in the construction of complex molecular frameworks, enabling the creation of novel compounds with medicinal, agricultural, and industrial applications. Its presence in the synthesis pathway often leads to improved efficiency, regioselectivity, and overall yield of the target molecules. By incorporating N-tert-Butyl-2-thiophenesulfonamide into chemical reactions, researchers can access a wide range of structural modifications and functional group transformations, making it an indispensable tool in the modern synthetic chemist's repertoire.

Literature

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101