1003575-43-6 | 3-Amino-4-fluorophenylboronic acid, pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$17.00	$12.00
1g	97%	in stock	$31.00	$22.00
5g	97%	in stock	$154.00	$108.00
10g	97%	in stock	$307.00	$215.00
25g	97%	in stock	$704.00	$493.00

Description

• Catalog Number: AA01996
• Chemical Name: 3-Amino-4-fluorophenylboronic acid, pinacol ester
• CAS Number: 1003575-43-6
• Molecular Formula: C12H17BFNO2
• Molecular Weight: 237.0783
• MDL Number: MFCD11044430
• SMILES: Fc1ccc(cc1N)B1OC(C(O1)(C)C)(C)C

Computed Properties

• Complexity: 282
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 17
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1

Upstream Synthesis Route

2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is a versatile compound widely used in chemical synthesis for its unique properties. This compound serves as a valuable building block in the synthesis of various organic molecules. Specifically, it is commonly employed in Suzuki-Miyaura cross-coupling reactions to introduce the 2-fluoroaniline moiety into complex molecular structures. The presence of the boronate ester group facilitates efficient coupling with aryl halides or pseudohalides, enabling the formation of C-C bonds with high regioselectivity and functional group tolerance. Additionally, the 2-fluoro substituent enhances the reactivity and selectivity of the coupling reaction, making this compound a valuable tool for the construction of biologically active molecules, pharmaceutical intermediates, and advanced materials.