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Discriminating between adaptive and carcinogenic liver hypertrophy in rat studies using logistic ridge regression analysis of toxicogenomic data: The mode of action and predictive models.
Toxicology and applied pharmacology 20170301
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Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries.
Toxicological sciences : an official journal of the Society of Toxicology 20160501
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Gene Expression Patterns Associated With Histopathology in Toxic Liver Fibrosis.
Toxicological sciences : an official journal of the Society of Toxicology 20160101
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4,4'-Methylenedianiline Alters Serotonergic Transport in a Novel, Sex-Specific Model of Pulmonary Arterial Hypertension in Rats.
Toxicological sciences : an official journal of the Society of Toxicology 20150901
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Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action.
PloS one 20140101
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Systems level analysis and identification of pathways and networks associated with liver fibrosis.
PloS one 20140101
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Occupational contact allergy to monomeric isocyanates.
Contact dermatitis 20120801
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Effect of ionic liquid on the determination of aromatic amines as contaminants in hair dyes by liquid chromatography coupled to electrochemical detection.
Molecules (Basel, Switzerland) 20120702
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SPR sensing of bisphenol A using molecularly imprinted nanoparticles immobilized on slab optical waveguide with consecutive parallel Au and Ag deposition bands coexistent with bisphenol A-immobilized Au nanoparticles.
Langmuir : the ACS journal of surfaces and colloids 20120501
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Dermal uptake study with 4,4'-diphenylmethane diisocyanate led to active sensitization.
Contact dermatitis 20120201
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Role of COX-2 in the bioactivation of methylenedianiline and in its proliferative effects in vascular smooth muscle cells.
Cardiovascular toxicology 20111201
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Aerobic biodegradation of amines in industrial saline wastewaters.
Chemosphere 20111101
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[Determination of seven aromatic amines in hair dyes by capillary electrophoresis coupled with field-amplified sample stacking].
Se pu = Chinese journal of chromatography 20111101
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Dermal uptake and excretion of 4,4'-methylenedianiline during rotor blade production in helicopter industry--an intervention study.
The Annals of occupational hygiene 20111001
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On the cause of controlling affinity to small molecules of imprinted polymeric membranes prepared by noncovalent approach: a computational and experimental investigation.
The journal of physical chemistry. B 20110804
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4,4'-Methylenedianiline-induced hepatitis in an industrial worker: case report and review of the literature.
Human & experimental toxicology 20110701
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N,N'-[4,4'-Methyl-enebis(4,1-phenyl-ene)]bis-(2,6-difluoro-benzamide).
Acta crystallographica. Section E, Structure reports online 20110701
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4,4'-Methylenebis{N-[(E)-quinolin-2-yl-methylidene]aniline}.
Acta crystallographica. Section E, Structure reports online 20110601
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Cellular and biomolecular responses of human ovarian cancer cells to cytostatic dinuclear platinum(II) complexes.
Apoptosis : an international journal on programmed cell death 20110301
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Synthesis of GN8 derivatives and evaluation of their antiprion activity in TSE-infected cells.
Bioorganic & medicinal chemistry letters 20110301
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Elimination kinetics of diisocyanates after specific inhalative challenges in humans: mass spectrometry analysis, as a basis for biomonitoring strategies.
Journal of occupational medicine and toxicology (London, England) 20110101
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4,4'‑Methylenedianiline and its dihydrochloride.
Report on carcinogens : carcinogen profiles 20110101
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[Studies on primary aromatic amines (PAAs) migration from multi-layer plastic food packaging by HPLC method].
Roczniki Panstwowego Zakladu Higieny 20110101
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A predictive ligand-based Bayesian model for human drug-induced liver injury.
Drug metabolism and disposition: the biological fate of chemicals 20101201
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Determination of aromatic amines in aqueous extracts of polyurethane foam using hydrophilic interaction liquid chromatography and mass spectrometry.
Analytica chimica acta 20100923
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Primary aromatic amines (PAAs) in black nylon and other food-contact materials, 2004-2009.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20100901
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Ortho-rhom-bic modification of bis-[4-(3-pyridyl-methyl-idene-amino)-phen-yl]methane.
Acta crystallographica. Section E, Structure reports online 20100901
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A structural and spectroscopic investigation of the hydrochlorination of 4,4'-methylenedianiline.
Physical chemistry chemical physics : PCCP 20100421
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Curing and dynamic mechanical thermal properties of epoxy/clay nanocomposites.
Journal of nanoscience and nanotechnology 20100401
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Validation of a liquid chromatography-mass spectrometry method for determining the migration of primary aromatic amines from cooking utensils and its application to actual samples.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20100101
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[Migration of monomers and primary aromatic amines from nylon products].
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20100101
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Expression of hepatocytic- and biliary-specific transcription factors in regenerating bile ducts during hepatocyte-to-biliary epithelial cell transdifferentiation.
Comparative hepatology 20100101
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The role of bridging ligands in determining DNA-binding ability and cross-linking patterns of dinuclear platinum(II) antitumour complexes.
Dalton transactions (Cambridge, England : 2003) 20091228
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New isocyanate-specific albumin adducts of 4,4'-methylenediphenyl diisocyanate (MDI) in rats.
Chemical research in toxicology 20091201
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Determination of aromatic amines in food products and composite food packaging bags by capillary electrophoresis coupled with transient isotachophoretic stacking.
Journal of chromatography. A 20091023
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Identification of urinary biomarkers useful for distinguishing a difference in mechanism of toxicity in rat model of cholestasis.
Basic & clinical pharmacology & toxicology 20090901
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In vivo evaluation of diaminodiphenyls: anticonvulsant agents with minimal acute neurotoxicity.
Bioorganic & medicinal chemistry letters 20090901
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N,N'-(Methyl-enedi-p-phenyl-ene)dibenzamide.
Acta crystallographica. Section E, Structure reports online 20090901
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[Analysis of primary aromatic amines in paper products].
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20090801
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Three cases of allergic contact dermatitis to 4,4'-diaminodiphenylmethane.
Contact dermatitis 20090601
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Synthesis and characterization of new optically active poly(azo-ester-imide)s via interfacial polycondensation.
Amino acids 20090301
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Characterization of biliary conjugates of 4,4'-methylenedianiline in male versus female rats.
Toxicology and applied pharmacology 20081015
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Reactivity of in vitro activated human T lymphocytes to p-phenylenediamine and related substances.
Contact dermatitis 20081001
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Study of the infrared spectral features of an epoxy curing mechanism.
Applied spectroscopy 20081001
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4,4'-Methyl-enedianilinium bis-(3-carb-oxy-4-hydroxy-benzene-sulfonate) monohydrate.
Acta crystallographica. Section E, Structure reports online 20081001
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Bis(1,2,3,4-tetra-hydro-quinolin-6-yl)methane.
Acta crystallographica. Section E, Structure reports online 20080901
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Contact sensitization to 4,4'-diaminodiphenylmethane and to isocyanates among general dermatology patients.
Contact dermatitis 20080801
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Organic-solvent extraction of model biomaterials for use in the in vitro chromosome aberration test.
Journal of biomedical materials research. Part A 20080701
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Time- and dose-based gene expression profiles produced by a bile-duct-damaging chemical, 4,4'-methylene dianiline, in mouse liver in an acute phase.
Toxicologic pathology 20080701
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Percutaneous absorption of aromatic amines - a contribution for human health risk assessment.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080601
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Liquid chromatography-electrospray tandem mass spectrometry investigations of fragmentation pathways of biliary 4,4'-methylenedianiline conjugates produced in rats.
Analytical and bioanalytical chemistry 20080501
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Validation of putative genomic biomarkers of nephrotoxicity in rats.
Toxicology 20080418
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Bis(4,4'-methyl-enedianilinium) naphthalene-1,5-disulfonate dihydrate.
Acta crystallographica. Section E, Structure reports online 20080401
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Bile duct destruction by 4,4'-diaminodiphenylmethane does not block the small hepatocyte-like progenitor cell response in retrorsine-exposed rats.
Hepatology (Baltimore, Md.) 20071101
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How to optimize patch testing with diphenylmethane diisocyanate.
Contact dermatitis 20070901
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A dinuclear monofunctional platinum(II) complex with an aromatic linker shows low reactivity towards glutathione but high DNA binding ability and antitumor activity.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20070601
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Biological monitoring of workers exposed to 4,4'-methylenediphenyl diisocyanate (MDI) in 19 French polyurethane industries.
International archives of occupational and environmental health 20070401
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Nanoscale confinement effects on the relaxation dynamics in networks of diglycidyl ether of bisphenol-A and low-molecular-weight poly(ethylene oxide).
The journal of physical chemistry. B 20070322
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Effects of methylenedianiline on tight junction permeability of biliary epithelial cells in vivo and in vitro.
Toxicology letters 20070227
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Determination of isocyanate biomarkers in construction site workers.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20070101
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Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.
Journal of molecular graphics & modelling 20061101
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Identification and characterization of functional rat arylamine N-acetyltransferase 3: comparisons with rat arylamine N-acetyltransferases 1 and 2.
The Journal of pharmacology and experimental therapeutics 20061001
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Biological monitoring of exposure to 1,5-naphthalene diisocyanate and 4,4'-methylenediphenyl diisocyanate.
International archives of occupational and environmental health 20060901
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Hemoglobin adducts as a marker of exposure to chemical substances, especially PRTR class I designated chemical substances.
Journal of occupational health 20060901
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Identification of metabolites of 4,4'-methylenedianiline in vascular smooth muscle cells by liquid chromatography-electrospray tandem mass spectrometry.
Journal of mass spectrometry : JMS 20060601
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Analysis of biomarkers in rats and dogs exposed to polymeric methylenediphenyl diisocyanate (pMDI) and its glutathione adduct.
Toxicology 20060515
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Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
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4,4'-methylenedianiline-induced hepatotoxicity is modified by N-acetyltransferase 2 (NAT2) acetylator polymorphism in the rat.
The Journal of pharmacology and experimental therapeutics 20060101
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Risk evaluation of occupational exposure to methylene dianiline and toluene diamine in polyurethane foam.
Human & experimental toxicology 20051201
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Specific determination of 20 primary aromatic amines in aqueous food simulants by liquid chromatography-electrospray ionization-tandem mass spectrometry.
Journal of chromatography. A 20051014
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Development of a large-scale chemogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action.
Journal of biotechnology 20050929
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Evaluation of liver and peripheral blood micronucleus assays with 9 chemicals using young rats. A study by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Japanese Environmental Mutagen Society (JEMS)-Mammalian Mutagenicity Study Group (MMS).
Mutation research 20050606
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Mitochondrial dysfunction occurs before transport or tight junction deficits in biliary epithelial cells exposed to bile from methylenedianiline-treated rats.
Toxicological sciences : an official journal of the Society of Toxicology 20050301
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Transdifferentiation of rat hepatocytes into biliary cells after bile duct ligation and toxic biliary injury.
Hepatology (Baltimore, Md.) 20050301
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Modeling of complex viscosity changes in the curing of epoxy resins from near-infrared spectroscopy and multivariate regression analysis.
Applied spectroscopy 20041201
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catena-Poly[[bis(pentane-2,4-dionato-kappa2O,O')cobalt(II)]-mu-4,4'-methylenedianiline-kappa2N:N'].
Acta crystallographica. Section C, Crystal structure communications 20041101
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The Epping Jaundice outbreak: mortality after 38 years of follow-up.
International archives of occupational and environmental health 20041101
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Replacing HCl by solid acids in industrial processes: synthesis of diamino diphenyl methane (DADPM) for producing polyurethanes.
Chemical communications (Cambridge, England) 20040907
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Bis-dinuclear (Cu-Gd)2 complexes with a probable helicate structure.
Dalton transactions (Cambridge, England : 2003) 20040607
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Allergic contact sensitivity in elderly patients.
Aging clinical and experimental research 20040601
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Efficient synthesis of poly(phenylazomethine) dendrons allowing access to higher generation dendrimers.
Organic letters 20040527
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Percutaneous penetration and genotoxicity of 4,4'-methylenedianiline through rat and human skin in vitro.
Toxicology 20040301
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Hydrolytic stability of toluene diisocyanate and polymeric methylenediphenyl diisocyanate based polyureas under environmental conditions.
Environmental science & technology 20040215
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In vitro evolution of RNA aptamers recognizing carcinogenic aromatic amines.
Biochemical and biophysical research communications 20040123
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Vascular medial hyperplasia following chronic, intermittent exposure to 4,4'-methylenedianiline.
Cardiovascular toxicology 20040101
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The origin of biliary ductular cells that appear in the spleen after transplantation of hepatocytes.
Cell transplantation 20040101
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4,4'-Methylenedianiline and its dihydrochloride salt.
Report on carcinogens : carcinogen profiles 20040101
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Isolation of methylene dianiline and aqueous-soluble biodegradation products from polycarbonate-polyurethanes.
Biomaterials 20030801
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Glutathione depletion exacerbates methylenedianiline toxicity to biliary epithelial cells and hepatocytes in rats.
Toxicological sciences : an official journal of the Society of Toxicology 20030801
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Allergic contact dermatitis from dicyclohexylmethane-4,4'-diisocyanate.
Contact dermatitis 20030601
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Occupational allergic contact dermatitis in a company manufacturing boards coated with isocyanate lacquer.
Contact dermatitis 20030501
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Concentration-dependence of biomarkers of exposure of methylenediphenyl-diisocyanate following acute inhalation exposure of rats.
Toxicology 20030314
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Determination of primary aromatic amines in water food simulant using solid-phase analytical derivatization followed by gas chromatography coupled with mass spectrometry.
Journal of chromatography. A 20030103
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Patch test sensitization to methylchloroisothiazolinone + methylisothiazolinone and 4,4'-diaminodiphenylmethane.
Contact dermatitis 20030101
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Development, validation and characterization of an analytical method for the quantification of hydrolysable urinary metabolites and plasma protein adducts of 2,4- and 2,6-toluene diisocyanate, 1,5-naphthalene diisocyanate and 4,4'-methylenediphenyl diisocyanate.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20030101
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Analysis of some aromatic amines by means of derivative spectrophotometry.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20021101
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Biological monitoring of aromatic diisocyanates in workers exposed to thermal degradation products of polyurethanes.
Journal of environmental monitoring : JEM 20021001
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Dielectric in situ monitoring of microgravity polymerizations.
Annals of the New York Academy of Sciences 20021001
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DNA damage induced by 4,4'-methylenedianiline in primary cultures of hepatocytes and thyreocytes from rats and humans.
Toxicology and applied pharmacology 20020801
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The spectrum of allergic (cross-)sensitivity in clinical patch testing with 'para amino' compounds.
Allergy 20020401
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Toxicity and biodegradation of diamines.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20020101
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4,4'-Methylenedianiline and its dihydrochloride salt.
Report on carcinogens : carcinogen profiles 20020101
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Differentiation of the mechanism of micronuclei induced by cysteine and glutathione conjugates of methylenedi-p-phenyl diisocyanate from that of 4,4'-methylenedianiline.
Mutation research 20011018
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Degradability of selected azo dye metabolites in activated sludge systems.
Chemosphere 20010801
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Diaminodiphenylmethane (DDM): frequency of sensitization, clinical relevance and concomitant positive reactions.
Contact dermatitis 20010501
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Exposure to 4,4'-methylenediphenyl diisocyanate (MDI) during moulding of rigid polyurethane foam: determination of airborne MDI and urinary 4,4'-methylenedianiline (MDA).
The Analyst 20010401
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Evaluation of the gender differences in 4,4'-methylenedianiline toxicity, distribution, and effects on biliary parameters.
Journal of toxicology and environmental health. Part A 20010323
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Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens.
Chemical research in toxicology 20010301
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A minimally toxic dose of methylene dianiline injures biliary epithelial cells in rats.
Toxicology and applied pharmacology 19980601
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Modulation of taurine levels in the rat liver alters methylene dianiline hepatotoxicity.
Toxicology 19971019
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Bile ductular damage induced by methylene dianiline inhibits oval cell activation.
The American journal of pathology 19971001
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Accidental intoxication with methylene dianiline p,p'-diaminodiphenylmethane: acute liver damage after presumed ecstasy consumption.
Journal of toxicology. Clinical toxicology 19970101
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Delayed and immediate allergy caused by methylhexahydrophthalic anhydride.
Contact dermatitis 19970101
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Occupational allergic contact dermatitis caused by 2,4,6-tris-(dimethylaminomethyl)phenol, and review of sensitizing epoxy resin hardeners.
International journal of dermatology 19961201
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Follow-up of a group of workers intoxicated with 4,4'-methylenedianiline.
American journal of industrial medicine 19940701
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Concomitant sensitization to triglycidyl isocyanurate, diaminodiphenylmethane and 2-hydroxyethyl methacrylate from silk-screen printing coatings in the manufacture of circuit boards.
Contact dermatitis 19940101
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Methylene dianiline hepatotoxicity is not leukocyte-dependent.
Toxicology and applied pharmacology 19940101
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Modifying influence of prior treatment with toxic agents on induction of preneoplastic and neoplastic lesions in a medium-term multi-organ carcinogenesis bioassay.
Teratogenesis, carcinogenesis, and mutagenesis 19930101
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Methylene dianiline: acute toxicity and effects on biliary function.
Toxicology and applied pharmacology 19921101
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Modifying effects of various chemicals on tumor development in a rat wide-spectrum organ carcinogenesis model.
Japanese journal of cancer research : Gann 19920801
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Toxicity of 1,4-bis(aminocyclohexyl)methane.
Journal of applied toxicology : JAT 19911001
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Study on cross-reactivity to the para group.
Dermatologica 19900101
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[The value of positive epicutaneous test reactions to 4,4'-diaminodiphenylmethane].
Dermatosen in Beruf und Umwelt. Occupation and environment 19890101
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Retinopathy from inhaling 4,4'-methylenedianiline aerosols.
Fundamental and applied toxicology : official journal of the Society of Toxicology 19871101
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Inhibition of neoplastic development in rat liver, kidney, oesophagus and forestomach by 4,4'-diaminodiphenylmethane administration.
Carcinogenesis 19870501
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Sensitization to methylenedianiline and para-structures.
Contact dermatitis 19870501
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[Change in the allergen spectrum in contact eczema 1975-1984].
Dermatosen in Beruf und Umwelt. Occupation and environment 19870101
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Inhibitory effects of ethoxyquin, 4,4'-diaminodiphenylmethane and acetaminophen on rat hepatocarcinogenesis.
Japanese journal of cancer research : Gann 19860301
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Carcinogenesis studies of 4,4'-methylenedianiline dihydrochloride given in drinking water to F344/N rats and B6C3F1 mice.
Journal of toxicology and environmental health 19860101
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Yellow staining caused by 4,4'-methylenedianiline exposure. Occurrence among molded plastics workers.
Archives of dermatology 19850801
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Methylene dianilene: a new toxic cause of visual failure with hepatitis.
Human toxicology 19850101
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Occupational hepatitis caused by methylenedianiline.
The Medical journal of Australia 19841013
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Neoplastic response of F344 rats and B6C3F1 mice to the polymer and dyestuff intermediates 4,4'-methylenebis(N,N-dimethyl)-benzenamine, 4,4'-oxydianiline, and 4,4'-methylenedianiline.
Journal of the National Cancer Institute 19840601
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Modification of the development of N-nitrosomorpholine-induced hepatic lesions by 2-acetylaminofluorene, phenobarbital and 4,4'-diaminodiphenylmethane: a sequential histological and histochemical analysis.
Carcinogenesis 19840301
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4,4'-Diaminodiphenylmethane: promoting effect on the development of thyroid tumors in rats treated with N-bis(2-hydroxypropyl)nitrosamine.
Journal of the National Cancer Institute 19840201
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[Infrahepatic bile duct proliferation in the gestating rat treated with 4,4'-diaminodiphenylmethane (4,4DDPM)].
Bulletin de l'Association des anatomistes 19831201
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Occupational photosensitivity to diaminodiphenylmethane.
Contact dermatitis 19831101
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Comparison of oval cells induced in rat liver by feeding N-2-fluorenylacetamide in a choline-devoid diet and bile duct cells induced by feeding 4,4'-diaminodiphenylmethane.
Cancer research 19830401
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Inhibitory effect of 4,4'-diaminodiphenylmethane on liver, kidney and bladder carcinogenesis in rats ingesting N-ethyl-N-hydroxyethylnitrosamine or N-butyl-N-(4-hydroxybutyl) nitros-amine.
Carcinogenesis 19810101
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Combined action of hepatotoxic substances and increased environmental temperature on the liver of rats.
Journal of hygiene, epidemiology, microbiology, and immunology 19800101
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Effect of various factors on the induction of liver tumors in animals by quinoline.
Gan 19771201