101-81-5 | Diphenylmethane

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$13.00	$9.00
5g	98%	in stock	$15.00	$10.00
10g	98%	in stock	$16.00	$11.00
25g	98%	in stock	$20.00	$14.00
100g	98%	in stock	$29.00	$20.00
500g	98%	in stock	$69.00	$49.00
5kg	98%	in stock	$472.00	$331.00
10kg	98%	in stock	$829.00	$580.00
25kg	98%	in stock	$1,907.00	$1,335.00

Description

• Catalog Number: AA04259
• Chemical Name: Diphenylmethane
• CAS Number: 101-81-5
• Molecular Formula: C13H12
• Molecular Weight: 168.2344
• MDL Number: MFCD00004781
• SMILES: c1ccc(cc1)Cc1ccccc1
• NSC Number: 4708

Computed Properties

• Complexity: 111
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Rotatable Bond Count: 2
• XLogP3: 4.1

Upstream Synthesis Route

Diphenylmethane, also known as benzophenone, is a compound commonly used in chemical synthesis for its versatile applications. In organic chemistry, diphenylmethane serves as a key building block for the synthesis of various complex molecules due to its unique structure and reactivity. One of its primary uses is as a photoinitiator in the formulation of UV-curable resins and coatings. When exposed to ultraviolet light, diphenylmethane undergoes a photoreaction to generate free radicals, initiating the polymerization process and leading to the formation of a crosslinked polymer network. This property makes diphenylmethane an essential component in the production of adhesives, inks, and coatings that require rapid curing under UV light. Additionally, diphenylmethane derivatives are employed as intermediates in the synthesis of pharmaceuticals, agrochemicals, and fragrances, showcasing its significance in modern chemical research and industries.

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  Psychopharmacology 20110501

• Changes in urodynamic parameters after tolterodine treatment for female overactive bladder syndrome with or without voiding dysfunction.

  The journal of obstetrics and gynaecology research 20110501

• Changing the substrate specificity of P450cam towards diphenylmethane by semi-rational enzyme engineering.

  Protein engineering, design & selection : PEDS 20110501

• Cerebral microglia mediate sleep/wake and neuroinflammatory effects of methamphetamine.

  Brain, behavior, and immunity 20110501

• Long-term safety, tolerability, and efficacy of fesoterodine treatment in men and women with overactive bladder symptoms.

  Current medical research and opinion 20110501

• Effect of fesoterodine 4 mg on bladder diary and patient-reported outcomes during the first week of treatment in subjects with overactive bladder.

  Current medical research and opinion 20110501

• Promising medications for cocaine dependence treatment.

  Recent patents on CNS drug discovery 20110501

• A potent and orally active antagonist (SM-406/AT-406) of multiple inhibitor of apoptosis proteins (IAPs) in clinical development for cancer treatment.

  Journal of medicinal chemistry 20110428

• Conformer-specific vibronic spectroscopy and vibronic coupling in a flexible bichromophore: bis-(4-hydroxyphenyl)methane.

  The Journal of chemical physics 20110428

• Direct arylation of simple azoles catalyzed by 1,10-phenanthroline containing palladium complexes: an investigation of C4 arylation of azoles and the synthesis of triarylated azoles by sequential arylation.

  The Journal of organic chemistry 20110415

• Activation of the Si-B linkage: copper-catalyzed addition of nucleophilic silicon to imines.

  Organic letters 20110415

• Severe mania complicating treatment of narcolepsy with cataplexy.

  Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20110415

• Phase 1 study of MLN8054, a selective inhibitor of Aurora A kinase in patients with advanced solid tumors.

  Cancer chemotherapy and pharmacology 20110401

• Synthesis and antioxidant capacities of hydroxyl derivatives of cinnamoylphenethylamine in protecting DNA and scavenging radicals.

  Free radical research 20110401

• Cognitive evoked potentials in narcolepsy: a review of the literature.

  Neuroscience and biobehavioral reviews 20110401

• Effect of modafinil on learning and task-related brain activity in methamphetamine-dependent and healthy individuals.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20110401

• The efficacy of additive tolterodine extended release for 1-year in older men with storage symptoms and clinical benign proastatic hyperplasia.

  Neurourology and urodynamics 20110401

• Mechanisms of drug sensitization to TRA-8, an agonistic death receptor 5 antibody, involve modulation of the intrinsic apoptotic pathway in human breast cancer cells.

  Molecular cancer research : MCR 20110401

• Double-blind randomized parallel-group clinical trial of efficacy of the combination fluoxetine plus modafinil versus fluoxetine plus placebo in the treatment of major depression.

  Depression and anxiety 20110401

• [Tolterodine tartrate combined with alpha-receptor blocker for benign prostatic hyperplasia with detrusor overactivity].

  Zhonghua nan ke xue = National journal of andrology 20110401

• Discovery of a new 2-aminobenzhydrol template for highly potent squalene synthase inhibitors.

  Bioorganic & medicinal chemistry 20110315

• Novel pyridazine based scorpionate ligands in cobalt and nickel boratrane compounds.

  Inorganic chemistry 20110307

• Effects of hepatic dysfunction on the single-dose pharmacokinetics of fesoterodine.

  Journal of clinical pharmacology 20110301

• Pharmacotherapy for the treatment of acute bipolar II depression: current evidence.

  The Journal of clinical psychiatry 20110301

• Correlates and predictors of patient satisfaction with drug therapy and combined drug therapy and behavioral training for urgency urinary incontinence in women.

  International urogynecology journal 20110301

• Evaluation of the effect of tolterodine on pupil diameter and anterior chamber parameters with the Pentacam.

  Cutaneous and ocular toxicology 20110301

• Effects of modafinil on emotional processing in first episode psychosis.

  Biological psychiatry 20110301

• Micropartioning and solubilization enhancement of 1,2-bis(bis(4-chlorophenyl) methyl)diselane in mixed micelles of binary and ternary cationic-nonionic surfactant mixtures.

  Colloids and surfaces. B, Biointerfaces 20110301

• The safety of modafinil in combination with oral ∆9-tetrahydrocannabinol in humans.

  Pharmacology, biochemistry, and behavior 20110301

• In vivo activity of the thyroid hormone receptor beta- and α-selective agonists GC-24 and CO23 on rat liver, heart, and brain.

  Endocrinology 20110301

• Validation of the urinary sensation scale (USS).

  Neurourology and urodynamics 20110301

• Synthesis of GN8 derivatives and evaluation of their antiprion activity in TSE-infected cells.

  Bioorganic & medicinal chemistry letters 20110301

• Excessive daytime sleepiness in patients with Parkinson's disease.

  CNS drugs 20110301

• Evaluation of brain anticholinergic activities of urinary spasmolytic drugs using a high-throughput radio receptor bioassay.

  Journal of the American Geriatrics Society 20110301

• Patient-optimized doses of fesoterodine improve bladder symptoms in an open-label, flexible-dose study.

  BJU international 20110201

• Early onset of fesoterodine efficacy in subjects with overactive bladder.

  BJU international 20110201

• The binding of synthetic triiodo l-thyronine analogs to human transthyretin: molecular basis of cooperative and non-cooperative ligand recognition.

  Journal of structural biology 20110201

• Evaluation of antioxidant activity of vanillin by using multiple antioxidant assays.

  Biochimica et biophysica acta 20110201

• Systemic exposure to armodafinil and its tolerability in healthy elderly versus young men: an open-label, multiple-dose, parallel-group study.

  Drugs & aging 20110201

• Modafinil and armodafinil treatment for fatigue for HIV-positive patients with and without chronic hepatitis C.

  International journal of STD & AIDS 20110201

• Dications of benzylidenefluorene and diphenylmethylidene fluorene: the relationship between magnetic and energetic measures of antiaromaticity.

  The Journal of organic chemistry 20110107

• A 2-week, polysomnographic, safety study of sodium oxybate in obstructive sleep apnea syndrome.

  Sleep & breathing = Schlaf & Atmung 20110101

• Overactive bladder drugs and constipation: a meta-analysis of randomized, placebo-controlled trials.

  Digestive diseases and sciences 20110101

• Wake-promoting agent modafinil worsened attentional performance following REM sleep deprivation in a young-adult rat model of 5-choice serial reaction time task.

  Psychopharmacology 20110101

• Differential effects of total sleep deprivation on contextual and spatial memory: modulatory effects of modafinil.

  Pharmacology, biochemistry, and behavior 20110101

• Investigation of the clinical efficacy and safety of pregabalin alone or combined with tolterodine in female subjects with idiopathic overactive bladder.

  Neurourology and urodynamics 20110101

• Wind-up of stretch reflexes as a measure of spasticity in chronic spinalized rats: The effects of passive exercise and modafinil.

  Experimental neurology 20110101

• Research is needed on the use of cognitive enhancer drugs in sport.

  Journal of science and medicine in sport 20110101

• Synthesis and biological evaluation of new derivatives of 2-substituted 4-hydroxybutanamides as GABA uptake inhibitors.

  European journal of medicinal chemistry 20110101

• KNK437 downregulates heat shock protein 27 of pancreatic cancer cells and enhances the cytotoxic effect of gemcitabine.

  Chemotherapy 20110101

• Comparison of intrathecal dotarizine and nimodipine treatments in cerebral vasospasm after subarachnoid hemorrhage: an experimental study in rabbits.

  Acta neurochirurgica. Supplement 20110101

• Facile synthesis and biological evaluation of 3,3-diphenylpropanoyl piperazines as T-type calcium channel blockers.

  Bioorganic & medicinal chemistry letters 20110101

• Mixed incontinence: comparing definitions in non-surgical patients.

  Neurourology and urodynamics 20110101

• KNK437, a benzylidene lactam compound, sensitises prostate cancer cells to the apoptotic effect of hyperthermia.

  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20110101

• Biomarkers predicting isocyanate-induced asthma.

  Allergy, asthma & immunology research 20110101

• [Comparisons of efficacy and safety of tolterodine and oxybutynin in children with idiopathic overactive bladder].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20110101

• Patient-reported outcomes as a source of evidence in off-label prescribing: analysis of data from PatientsLikeMe.

  Journal of medical Internet research 20110101

• Bisphenol A induces otolith malformations during vertebrate embryogenesis.

  BMC developmental biology 20110101

• [The diagnosis and treatment of abnormal uterine bleeding in nonpregnant patients with hepatic cirrhosis].

  Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20110101

• Efficacy and tolerability of solifenacin in patients aged ≥ 65 years with overactive bladder: post-hoc analysis of 2 open-label studies.

  Postgraduate medicine 20110101

• Kleine-Levin syndrome and response to modafinil in a young woman.

  The Journal of neuropsychiatry and clinical neurosciences 20110101

• A biregional survey and review of first-line treatment failure and second-line paediatric antiretroviral access and use in Asia and southern Africa.

  Journal of the International AIDS Society 20110101

• Immune sensitization to methylene diphenyl diisocyanate (MDI) resulting from skin exposure: albumin as a carrier protein connecting skin exposure to subsequent respiratory responses.

  Journal of occupational medicine and toxicology (London, England) 20110101

• Elimination kinetics of diisocyanates after specific inhalative challenges in humans: mass spectrometry analysis, as a basis for biomonitoring strategies.

  Journal of occupational medicine and toxicology (London, England) 20110101

• Reining in the pharmacological enhancement train: we should remain vigilant about regulatory standards for prescribing controlled substances.

  The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 20110101

• The application of rational design on phospholipase A(2) inhibitors.

  Current medicinal chemistry 20110101

• Syntheses of secocyclolignanes and comparative antioxidative activity between secocyclolignane and the dibenzyl type of lignan.

  Bioscience, biotechnology, and biochemistry 20110101

• Unusual behavior in the reactivity of 5-substituted-1H-tetrazoles in a resistively heated microreactor.

  Beilstein journal of organic chemistry 20110101

• Improved cellular uptake of antisense peptide nucleic acids by conjugation to a cell-penetrating peptide and a lipid domain.

  Methods in molecular biology (Clifton, N.J.) 20110101

• Binding mode prediction and inhibitor design of anti-influenza virus diketo acids targeting metalloenzyme RNA polymerase by molecular docking.

  Bioinformation 20110101

• Human neuroblastoma SH-SY5Y cells show increased resistance to hyperthermic stress after differentiation, associated with elevated levels of Hsp72.

  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20110101

• Treatment of HIV-related fatigue with armodafinil: a placebo-controlled randomized trial.

  Psychosomatics 20110101

• Inhalation of ortho-phthalaldehyde vapor causes respiratory sensitization in mice.

  Journal of allergy 20110101

• Haptenation: chemical reactivity and protein binding.

  Journal of allergy 20110101

• Bromophenols in marine algae and their bioactivities.

  Marine drugs 20110101

• Cocaine Addiction Treatments to improve Control and reduce Harm (CATCH): new pharmacological treatment options for crack-cocaine dependence in the Netherlands.

  BMC psychiatry 20110101

• Structure-activity relationship of halophenols as a new class of protein tyrosine kinase inhibitors.

  International journal of molecular sciences 20110101

• Intracellular ROS protection efficiency and free radical-scavenging activity of curcumin.

  PloS one 20110101

• The atypical stimulant and nootropic modafinil interacts with the dopamine transporter in a different manner than classical cocaine-like inhibitors.

  PloS one 20110101

• Technology-based self-care methods of improving antiretroviral adherence: a systematic review.

  PloS one 20110101

• Are prescribing doctors sensitive to the price that their patients have to pay in the Spanish National Health System?

  BMC health services research 20110101

• [Asthenia in advanced cancer and the use of psychostimulants].

  Anales del sistema sanitario de Navarra 20110101

• [Administration of M-cholinoblockers after prostatic surgery].

  Urologiia (Moscow, Russia : 1999) 20110101

• A practical guide for estimating rates of heterolysis reactions.

  Accounts of chemical research 20101221

• Pharmacologic approaches for the management of symptoms and cardiovascular consequences of obstructive sleep apnea in adults.

  Sleep & breathing = Schlaf & Atmung 20101201

• Electrical stimulation compared with tolterodine for treatment of urge/urge incontinence amongst women--a randomized controlled trial.

  International urogynecology journal 20101201

• Effects of acute modafinil on cognition in trichotillomania.

  Psychopharmacology 20101201

• Erythropoietin reverses the attentional set-shifting impairment in a rodent schizophrenia disease-like model.

  Psychopharmacology 20101201

• The selective dopamine uptake inhibitor, D-84, suppresses cocaine self-administration, but does not occasion cocaine-like levels of generalization.

  European journal of pharmacology 20101201

• Efficacy and tolerability of fesoterodine in older and younger subjects with overactive bladder.

  Urology 20101201

• [Modafinil for the treatment of cancer-related fatigue : an intervention study].

  Schmerz (Berlin, Germany) 20101201

• Changing baseline characteristics among patients in the China National Free Antiretroviral Treatment Program, 2002-09.

  International journal of epidemiology 20101201

• The effects of modafinil treatment on neuropsychological and attentional bias performance during 7-day inpatient withdrawal from methamphetamine dependence.

  Experimental and clinical psychopharmacology 20101201

• Coming into focus. Pharmacologic treatment for ADHD.

  Advance for NPs & PAs 20101201

• Modafinil is not the new caffeine.

  Neurology 20101116

• Modafinil ameliorates excessive daytime sleepiness after traumatic brain injury.

  Neurology 20101116

• A positron emission tomography study examining the dopaminergic activity of armodafinil in adults using [¹¹C]altropane and [¹¹C]raclopride.

  Biological psychiatry 20101115

• Pharmacological treatments for fatigue associated with palliative care.

  The Cochrane database of systematic reviews 20101110

• Importance of the nature of α-substituents in pyrrolidine organocatalysts in asymmetric Michael additions.

  The Journal of organic chemistry 20101105

• Controlling electron transfer in donor-bridge-acceptor molecules using cross-conjugated bridges.

  Journal of the American Chemical Society 20101103

• Effects of modafinil and prazosin on cognitive and physiological functions in healthy volunteers.

  Journal of psychopharmacology (Oxford, England) 20101101

• Efficacy and safety of tolterodine extended-release in men with overactive bladder symptoms treated with an α-blocker: effect of baseline prostate-specific antigen concentration.

  BJU international 20101101

• A follow-up study of modafinil for the treatment of daytime somnolence and fatigue in primary biliary cirrhosis.

  Liver international : official journal of the International Association for the Study of the Liver 20101101

• Armodafinil as adjunctive therapy in adults with cognitive deficits associated with schizophrenia: a 4-week, double-blind, placebo-controlled study.

  The Journal of clinical psychiatry 20101101

• Efficacy of extended-release tolterodine for the treatment of neurogenic detrusor overactivity and/or low-compliance bladder.

  International journal of urology : official journal of the Japanese Urological Association 20101101

• Clinical and therapeutic aspects of childhood narcolepsy-cataplexy: a retrospective study of 51 children.

  Sleep 20101101

• Pharmacokinetics of armodafinil and modafinil after single and multiple doses in patients with excessive sleepiness associated with treated obstructive sleep apnea: a randomized, open-label, crossover study.

  Clinical therapeutics 20101101

• Behavioral and cross sensitization after repeated exposure to modafinil and apomorphine in rats.

  The Chinese journal of physiology 20101031

• Effect of modafinil on learning performance and neocortical long-term potentiation in rats.

  Brain research bulletin 20101030

• Modanifil activates the histaminergic system through the orexinergic neurons.

  Neuroscience letters 20101015

• Probing nitrobenzhydrol uncaging mechanisms using FerriCast.

  Organic letters 20101015

• Temperature as a universal resetting cue for mammalian circadian oscillators.

  Science (New York, N.Y.) 20101015

• Tolerability and efficacy of armodafinil in naïve patients with excessive sleepiness associated with obstructive sleep apnea, shift work disorder, or narcolepsy: a 12-month, open-label, flexible-dose study with an extension period.

  Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20101015

• The long-term tolerability and efficacy of armodafinil in patients with excessive sleepiness associated with treated obstructive sleep apnea, shift work disorder, or narcolepsy: an open-label extension study.

  Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20101015

• Characterisation of hydrazides and hydrazine derivatives as novel aspartic protease inhibitors.

  Journal of enzyme inhibition and medicinal chemistry 20101001

• Synthesis and antioxidant properties of diphenylmethane derivative bromophenols including a natural product.

  Journal of enzyme inhibition and medicinal chemistry 20101001

• The effect of tolterodine 4 and 8 mg on the heart rate variability in healthy subjects.

  World journal of urology 20101001

• Modafinil reduces microsleep during partial sleep deprivation in depressed patients.

  Journal of psychiatric research 20101001

• The outcome of adding peripheral neuromodulation (Stoller afferent neuro-stimulation) to anti-muscarinic therapy in women with severe overactive bladder.

  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20101001

• Intracellular or extracellular heat shock protein 70 differentially regulates cardiac remodelling in pressure overload mice.

  Cardiovascular research 20101001

• Modafinil blocks reinstatement of extinguished opiate-seeking in rats: mediation by a glutamate mechanism.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20101001

• Sodium oxybate and modafinil: a good combination?

  Sleep medicine 20101001

• Sensitive determination of bisphenol A and bisphenol F in canned food using a solid-phase microextraction fibre coated with single-walled carbon nanotubes before GC/MS.

  Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20101001

• Adjunctive armodafinil for major depressive episodes associated with bipolar I disorder: a randomized, multicenter, double-blind, placebo-controlled, proof-of-concept study.

  The Journal of clinical psychiatry 20101001

• Clinical and neurocognitive changes with modafinil in obsessive-compulsive disorder: a case report.

  Psychopharmacology 20101001

• Targeting heat shock protein 72 enhances Hsp90 inhibitor-induced apoptosis in myeloma.

  Leukemia 20101001

• Loss of muscarinic and purinergic receptors in urinary bladder of rats with hydrochloric acid-induced cystitis.

  Urology 20101001

• Modafinil reverses hypoexcitability of the motor cortex in narcoleptic patients: a TMS study.

  Sleep medicine 20101001

• The effect of modafinil on cortical excitability in patients with narcolepsy: a randomized, placebo-controlled, crossover study.

  Sleep medicine 20101001

• Synthesis and comparative properties of two amide-generating resin linkers for use in solid phase peptide synthesis.

  Journal of peptide science : an official publication of the European Peptide Society 20101001

• Neuraxial anaesthesia for caesarean section in a patient with narcolepsy and cataplexy.

  International journal of obstetric anesthesia 20101001

• Benzhydrylamine linker grafting: a strategy for the improved synthesis of C-terminal peptide amides.

  Journal of peptide science : an official publication of the European Peptide Society 20101001

• Behavioral evaluation of modafinil and the abuse-related effects of cocaine in rhesus monkeys.

  Experimental and clinical psychopharmacology 20101001

• Solifenacin and tolterodine are equally effective in the treatment of overactive bladder symptoms.

  Journal of the Formosan Medical Association = Taiwan yi zhi 20101001

• 3-Benzoyl-1,1-dibenzyl-thio-urea.

  Acta crystallographica. Section E, Structure reports online 20101001

• Studies on the preparation, characterization and pharmacological evaluation of tolterodine PLGA microspheres.

  International journal of pharmaceutics 20100915

• Functional groups and sulfur K-edge XANES spectra: divalent sulfur and disulfides.

  The journal of physical chemistry. A 20100909

• Heme oxygenase inhibition by 1-aryl-2-(1h-imidazol-1-yl/1h-1,2,4-triazol-1-yl)ethanones and their derivatives.

  ChemMedChem 20100903

• Fesoterodine in patients with overactive bladder syndrome: can the severity of baseline urgency urinary incontinence predict dosing requirement?

  BJU international 20100901

• A retrospective review of supratherapeutic modafinil exposures.

  Journal of medical toxicology : official journal of the American College of Medical Toxicology 20100901

• The discrepancy in attention deficit hyperactivity disorder (ADHD) medications diffusion: 1994-2003--a global pharmaceutical data analysis.

  Health policy (Amsterdam, Netherlands) 20100901

• Modafinil and methylphenidate for neuroenhancement in healthy individuals: A systematic review.

  Pharmacological research 20100901

• Effect of the CYP2D6*10 genotype on tolterodine pharmacokinetics.

  Drug metabolism and disposition: the biological fate of chemicals 20100901

• Activation of mGluR7s inhibits cocaine-induced reinstatement of drug-seeking behavior by a nucleus accumbens glutamate-mGluR2/3 mechanism in rats.

  Journal of neurochemistry 20100901

• Modulatory effects of modafinil on neural circuits regulating emotion and cognition.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100901

• The antidepressant-like action of metabotropic glutamate 7 receptor agonist N,N'-bis(diphenylmethyl)-1,2-ethanediamine (AMN082) is serotonin-dependent.

  The Journal of pharmacology and experimental therapeutics 20100901

• Sleep restriction for 1 week reduces insulin sensitivity in healthy men.

  Diabetes 20100901

• Determination of the binding constants of modafinil enantiomers with sulfated β-cyclodextrin chiral selector by capillary electrophoresis using three different linear plotting methods.

  Electrophoresis 20100901

• [Preclinical approaches for drugs targeting cognitive deficits of schizophrenia].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20100901

• [Combination of tamsulosin and tolterodine alleviates refractory lower urinary tract symptoms in male patients].

  Zhonghua nan ke xue = National journal of andrology 20100901

• Seeking passe-partout in the catalytic asymmetric aziridination of imines: evolving toward substrate generality for a single chemzyme.

  The Journal of organic chemistry 20100820

• Structural optimization and biological evaluation of substituted bisphenol A derivatives as beta-amyloid peptide aggregation inhibitors.

  Journal of medicinal chemistry 20100812

• Armodafinil (Nuvigil) for wakefulness.

  The Medical letter on drugs and therapeutics 20100809

• The cost-effectiveness of solifenacin vs fesoterodine, oxybutynin immediate-release, propiverine, tolterodine extended-release and tolterodine immediate-release in the treatment of patients with overactive bladder in the UK National Health Service.

  BJU international 20100801

• AMN082 promotes the proliferation and differentiation of neural progenitor cells with influence on phosphorylation of MAPK signaling pathways.

  Neurochemistry international 20100801

• Effect of modafinil on impairments in neurobehavioral performance and learning associated with extended wakefulness and circadian misalignment.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100801

• A multicenter, double-blind, randomized, placebo controlled trial of a neurokinin-1 receptor antagonist for overactive bladder.

  The Journal of urology 20100801

• Spinal effects of the fesoterodine metabolite 5-hydroxymethyl tolterodine and/or doxazosin in rats with or without partial urethral obstruction.

  The Journal of urology 20100801

• The cost-effectiveness of solifenacin vs fesoterodine, oxybutynin immediate-release, propiverine, tolterodine extended-release and tolterodine immediate-release in the treatment of patients with overactive bladder in the UK National Health Service.

  BJU international 20100801

• Modafinil for narcolepsy: systematic review and meta-analysis.

  Medical science monitor : international medical journal of experimental and clinical research 20100801

• Fatigue and stimulant use in military fighter aircrew during combat operations.

  Aviation, space, and environmental medicine 20100801

• [Pharmacological neuroenhancement and brain doping : Chances and risks].

  Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 20100801

• Efficacy of modafinil in 10 Taiwanese patients with narcolepsy: findings using the Multiple Sleep Latency Test and Epworth Sleepiness Scale.

  The Kaohsiung journal of medical sciences 20100801

• Effects of combined behavioral intervention and tolterodine on patient-reported outcomes.

  The Canadian journal of urology 20100801

• [An experience of administration of modafinil for excessive daytime sleepiness in a patient with myotonic dystorophy].

  Rinsho shinkeigaku = Clinical neurology 20100801

• Effects of modafinil on the sleep EEG depend on Val158Met genotype of COMT.

  Sleep 20100801

• Benzyl N-{(1S)-2-hy-droxy-1-[N'-(2-nitro-benzyl-idene)hydrazinylcarbon-yl]eth-yl}carbamate.

  Acta crystallographica. Section E, Structure reports online 20100801

• A phase 3 randomized, placebo-controlled, double-blind, clinical trial of the effect of modafinil on cancer-related fatigue among 631 patients receiving chemotherapy: a University of Rochester Cancer Center Community Clinical Oncology Program Research base study.

  Cancer 20100715

• Urodynamic evaluation of fesoterodine metabolite, doxazosin and their combination in a rat model of partial urethral obstruction.

  BJU international 20100701

• Inhibitory effect of anticholinergics on the contraction of isolated caprine urinary bladder detrusor muscle.

  Autonomic & autacoid pharmacology 20100701

• A novel nonsecosteroidal VDR agonist (CH5036249) exhibits efficacy in a spontaneous benign prostatic hyperplasia beagle model.

  The Journal of steroid biochemistry and molecular biology 20100701

• Comparison of selective M3 and nonselective muscarinic receptor antagonists on gastrointestinal transit and bowel habits in humans.

  American journal of physiology. Gastrointestinal and liver physiology 20100701

• Expert opinion on pharmacotherapy of narcolepsy.

  Expert opinion on pharmacotherapy 20100701

• A phase 3, double-blind, randomized, placebo-controlled study of armodafinil for excessive sleepiness associated with jet lag disorder.

  Mayo Clinic proceedings 20100701

• Metabolic response of the cerebral cortex following gentle sleep deprivation and modafinil administration.

  Sleep 20100701

• Effects of paraxanthine and caffeine on sleep, locomotor activity, and body temperature in orexin/ataxin-3 transgenic narcoleptic mice.

  Sleep 20100701

• Modafinil prevents inhibitory avoidance memory deficit induced by sleep deprivation in rats.

  Sleep 20100701

• Abstracts of Fourth Ditan International Conference on Infectious Diseases - Changing Face of Infectious Diseases. 15-18 July 2010, Beijing.

  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20100701

• Bipolar disorder: an update.

  Postgraduate medicine 20100701

• Abrogating HSP response augments cell death induced by As2O3 in glioma cell lines.

  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20100701

• New strategies for medical management of overactive bladder in children.

  Current opinion in urology 20100701

• (E)-1-Diphenyl-methyl-idene-2-[(1H-indol-3-yl)methyl-idene]hydrazine.

  Acta crystallographica. Section E, Structure reports online 20100701

• 3-Benzyl-6-bromo-2-(2-fur-yl)-3H-imidazo[4,5-b]pyridine.

  Acta crystallographica. Section E, Structure reports online 20100701

• Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor.

  Cancer cell 20100615

• Using electronic drug monitor feedback to improve adherence to antiretroviral therapy among HIV-positive patients in China.

  AIDS and behavior 20100601

• Effect of fluid management on fluid intake and urge incontinence in a trial for overactive bladder in women.

  BJU international 20100601

• Modafinil effects on cognitive function in HIV+ patients treated for fatigue: a placebo controlled study.

  Journal of clinical and experimental neuropsychology 20100601

• Symptomatic and quality of life response to tolterodine in subgroups of men with overactive bladder symptoms and presumed non-obstructive benign prostatic hyperplasia.

  World journal of urology 20100601

• Single-dose pharmacokinetics and pharmacodynamics of sergliflozin etabonate, a novel inhibitor of glucose reabsorption, in healthy volunteers and patients with type 2 diabetes mellitus.

  Journal of clinical pharmacology 20100601

• Randomized, double-blind, placebo-controlled trial of modafinil for the treatment of methamphetamine dependence.

  Drug and alcohol dependence 20100601

• Treatment of acute mania with modafinil monotherapy.

  Biological psychiatry 20100601

• The effects of drug and behavior therapy on urgency and voiding frequency.

  International urogynecology journal 20100601

• Celastrol can inhibit proteasome activity and upregulate the expression of heat shock protein genes, hsp30 and hsp70, in Xenopus laevis A6 cells.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20100601

• Multiple-dose pharmacokinetics and pharmacodynamics of sergliflozin etabonate, a novel inhibitor of glucose reabsorption, in healthy overweight and obese subjects: a randomized double-blind study.

  Journal of clinical pharmacology 20100601

• The novel ketoprofen amides--synthesis and biological evaluation as antioxidants, lipoxygenase inhibitors and cytostatic agents.

  Chemical biology & drug design 20100601

• Psychostimulant-like discriminative stimulus and locomotor sensitization properties of the wake-promoting agent modafinil in rodents.

  Pharmacology, biochemistry, and behavior 20100601

• Modafinil effects on reinstatement of methamphetamine seeking in a rat model of relapse.

  Psychopharmacology 20100601

• Effects of modafinil and methylphenidate on visual attention capacity: a TVA-based study.

  Psychopharmacology 20100601

• Phenotypically directed multimodal therapy for chronic prostatitis/chronic pelvic pain syndrome: a prospective study using UPOINT.

  Urology 20100601

• Dopamine transporter-related effects of modafinil in rhesus monkeys.

  Psychopharmacology 20100601

• Modafinil for the treatment of multiple sclerosis-related fatigue.

  The Annals of pharmacotherapy 20100601

• Fatigue in primary biliary cirrhosis.

  Nature reviews. Gastroenterology & hepatology 20100601

• Modafinil-associated vivid visual hallucination in a patient with Kleine-Levin syndrome: case report.

  Journal of clinical psychopharmacology 20100601

• Modafinil use in patients with a primary psychiatric illness.

  The Australian and New Zealand journal of psychiatry 20100601

• Medication effects on sleep.

  Clinics in chest medicine 20100601

• Modafinil treatment for fatigue in HIV/AIDS: a randomized placebo-controlled study.

  The Journal of clinical psychiatry 20100601

• [A drug seeks its disease].

  Lakartidningen 20100601

• Cognitive enhancement, cheating, and accomplishment.

  Kennedy Institute of Ethics journal 20100601

• Bis[4-(diphenyl-methyl-eneamino)phen-yl]methanone.

  Acta crystallographica. Section E, Structure reports online 20100601

• Response to fesoterodine in patients with an overactive bladder and urgency urinary incontinence is independent of the urodynamic finding of detrusor overactivity.

  BJU international 20100501

• Efficacy and tolerability of fesoterodine in men with overactive bladder: a pooled analysis of 2 phase III studies.

  Urology 20100501

• Rapid occurrence of depression following addition of sodium oxybate to modafinil.

  Sleep medicine 20100501

• Efficacy and safety of tolterodine extended release and dutasteride in male overactive bladder patients with prostates >30 grams.

  Urology 20100501

• Central nervous system findings on functional magnetic resonance imaging in patients before and after treatment with anticholinergic medication.

  The Journal of urology 20100501

• Odor identification ability predicts executive function deficits following sleep deprivation.

  The International journal of neuroscience 20100501

• Impaired metabolic effects of a thyroid hormone receptor beta-selective agonist in a mouse model of diet-induced obesity.

  Thyroid : official journal of the American Thyroid Association 20100501

• Thorough QT study of the effect of fesoterodine on cardiac repolarization.

  International journal of clinical pharmacology and therapeutics 20100501

• A novel role for the metabotropic glutamate receptor-7: modulation of faecal water content and colonic electrolyte transport in the mouse.

  British journal of pharmacology 20100501

• Syndrome of inappropriate antidiuretic hormone associated with tolterodine therapy.

  The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20100501

• A cost-effectiveness analysis of modafinil therapy for psychostimulant dependence.

  Drug and alcohol review 20100501

• N-Formyl-3,4-methylenedioxy-benzylidene-gamma-butyrolaetam, KNK437 induces caspase-3 activation through inhibition of mTORC1 activity in Cos-1 cells.

  Biochemical and biophysical research communications 20100423

• Comment on 'Modafinil shifts human locus coeruleus to low-tonic, high-phasic activity during functional MRI' and 'Homeostatic sleep pressure and responses to sustained attention in the suprachiasmatic area'.

  Science (New York, N.Y.) 20100416

• Modafinil effects during acute continuous positive airway pressure withdrawal: a randomized crossover double-blind placebo-controlled trial.

  American journal of respiratory and critical care medicine 20100415

• Action of modafinil--increased motivation via the dopamine transporter inhibition and D1 receptors?

  Biological psychiatry 20100415

• Antimicrobial selaginellin derivatives from Selaginella pulvinata.

  Bioorganic & medicinal chemistry letters 20100415

• Formaldehyde in the indoor environment.

  Chemical reviews 20100414

• Anti-bovine viral diarrhoea virus activity of novel diphenylmethane derivatives.

  Antiviral chemistry & chemotherapy 20100414

• Tolterodine causes measurable restoration of urethral sensation in women with urge urinary incontinence.

  Neurourology and urodynamics 20100401

• Efficacy of fesoterodine over 24 hours in subjects with overactive bladder.

  Current medical research and opinion 20100401

• Long-term safety, tolerability and efficacy of fesoterodine treatment in subjects with overactive bladder symptoms.

  International journal of clinical practice 20100401

• Population pharmacokinetics of modafinil in Chinese Han, Mongolian, Korean, Uygur, and Hui healthy subjects determined by nonlinear mixed-effects modeling.

  Therapeutic drug monitoring 20100401

• Armodafinil in the treatment of excessive sleepiness.

  Expert opinion on pharmacotherapy 20100401

• A prospective observational study of the effects of treatment with extended-release tolterodine on health-related quality of life of patients suffering overactive bladder syndrome in Sweden.

  Scandinavian journal of urology and nephrology 20100401

• Mixed incontinence: current evidence and future perspectives.

  Neurourology and urodynamics 20100401

• Durability of treatments for overactive bladder.

  International journal of clinical practice 20100401

• National narcolepsy survey.

  Irish medical journal 20100401

• Working memory fMRI activation in cocaine-dependent subjects: association with treatment response.

  Psychiatry research 20100330

• Age-dependent effects of modafinil on acoustic startle and prepulse inhibition in rats.

  Behavioural brain research 20100317

• Antioxidant activity of alpha-pyridoin and its derivatives: possible mechanism.

  Organic & biomolecular chemistry 20100307

• Proof of principle: The effect of antimuscarinics on bladder filling sensations in healthy subjects--a placebo controlled double blind investigation using 4 and 8 mg tolterodine extended release.

  Neurourology and urodynamics 20100301

• Modafinil for Parkinson's disease fatigue.

  Journal of neurology 20100301

• Enhanced OECD TG 407 in detection of endocrine-mediated effects of 4,4'-(octahydro-4,7-methano-5H-inden-5-ylidene)bisphenol.

  Archives of toxicology 20100301

• Metabotropic glutamate 7 receptor subtype modulates motor symptoms in rodent models of Parkinson's disease.

  The Journal of pharmacology and experimental therapeutics 20100301

• Heat shock cognate protein 70 is essential for Akt signaling in endothelial function.

  Arteriosclerosis, thrombosis, and vascular biology 20100301

• Discovery of benzhydrylpiperazine derivatives as CB1 receptor inverse agonists via privileged structure-based approach.

  European journal of medicinal chemistry 20100301

• Normalizing effects of modafinil on sleep in chronic cocaine users.

  The American journal of psychiatry 20100301

• Exploration of SAR features by modifications of thiazoleacetic acids as CRTH2 antagonists.

  Bioorganic & medicinal chemistry letters 20100301

• Assessment and management of fatigue in neuromuscular disease.

  The American journal of hospice & palliative care 20100301

• Normalizing effects of modafinil on cocaine-induced sleep abnormalities.

  The American journal of psychiatry 20100301

• Extensive Analysis of Elastase-Induced Pulmonary Emphysema in Rats: ALP in the Lung, a New Biomarker for Disease Progression?

  Journal of clinical biochemistry and nutrition 20100301

• Enzymatic deprotection of the cephalosporin 3'-acetoxy group using Candida antarctica lipase B.

  The Journal of organic chemistry 20100219

• Computational studies of ion-pair separation of benzylic organolithium compounds in THF: importance of explicit and implicit solvation.

  The Journal of organic chemistry 20100219

• Structure-activity relationships of diphenylpiperazine N-type calcium channel inhibitors.

  Bioorganic & medicinal chemistry letters 20100215

• Modafinil reduces patient-reported tiredness after sedation/analgesia but does not improve patient psychomotor skills.

  Acta anaesthesiologica Scandinavica 20100201

• The pharmacokinetic profile of fesoterodine 8 mg with daytime or nighttime dosing.

  European journal of clinical pharmacology 20100201

• Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 2.

  Bioorganic & medicinal chemistry letters 20100201

• New Drugs2010, PART 1.

  Nursing 20100201

• Design of new secreted phospholipase A2 inhibitors based on docking calculations by modifying the pharmacophore segments of the FPL67047XX inhibitor.

  Journal of computer-aided molecular design 20100201

• Pediatrics: combining antimuscarinics shows promise for overactive bladder.

  Nature reviews. Urology 20100201

• Agonist-like pharmacotherapy for stimulant dependence: preclinical, human laboratory, and clinical studies.

  Annals of the New York Academy of Sciences 20100201

• Fesoterodine fumarate.

  Drugs of today (Barcelona, Spain : 1998) 20100201

• 1-Diphenyl-methyl-ene-2-(9H-fluoren-9-yl-idene)hydrazine.

  Acta crystallographica. Section E, Structure reports online 20100201

• Evaluation of modafinil effects on cardiovascular, subjective, and reinforcing effects of methamphetamine in methamphetamine-dependent volunteers.

  Drug and alcohol dependence 20100115

• Modafinil does not serve as a reinforcer in cocaine abusers.

  Drug and alcohol dependence 20100115

• Highly enantioselective titanium-catalyzed cyanation of imines at room temperature.

  Organic letters 20100115

• A preparation of N-Fmoc-N-methyl-alpha-amino acids and N-nosyl-N-methyl-alpha-amino acids.

  Amino acids 20100101

• Recent advances in mass spectrometry analysis of phenolic endocrine disruptors and related compounds.

  Mass spectrometry reviews 20100101

• The antiarrhythmic properties of quifenadine, H1-histamine receptor blocker in children with premature beats: a randomized controlled pilot trial.

  American journal of therapeutics 20100101

• The effects of oral administration of d-modafinil on male rat ejaculatory behavior.

  The journal of sexual medicine 20100101

• Modafinil for multiple sclerosis fatigue: does it work?

  Clinical neurology and neurosurgery 20100101

• A safety trial of sodium oxybate in patients with obstructive sleep apnea: Acute effects on sleep-disordered breathing.

  Sleep medicine 20100101

• Randomized, double-blind, placebo-controlled trial of flexible-dose fesoterodine in subjects with overactive bladder.

  Urology 20100101

• Modafinil: an anti-relapse medication.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100101

• Pharmacological and genetic analysis of mechanisms underlying detrusor overactivity in rats.

  Neurourology and urodynamics 20100101

• A double-blind, placebo-controlled study of armodafinil for excessive sleepiness in patients with treated obstructive sleep apnea and comorbid depression.

  The Journal of clinical psychiatry 20100101

• Effect of the C3a-receptor antagonist SB 290157 on anti-OVA polyclonal antibody-induced arthritis.

  Journal of pharmacological sciences 20100101

• Managing the patient with shift-work disorder.

  The Journal of family practice 20100101

• Comparison of fesoterodine and tolterodine extended release for the treatment of overactive bladder: a head-to-head placebo-controlled trial.

  BJU international 20100101

• Pathological gambling associated with modafinil.

  The Journal of neuropsychiatry and clinical neurosciences 20100101

• Modafinil for bipolar depression with comorbid methamphetamine abuse.

  The American journal on addictions 20100101

• Contributors to satisfaction with combined drug and behavioral therapy for overactive bladder in subjects dissatisfied with prior drug treatment.

  Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society 20100101

• The psychostimulant modafinil facilitates water maze performance and augments synaptic potentiation in dentate gyrus.

  Neuropharmacology 20100101

• Armodafinil for fibromyalgia fatigue.

  The Annals of pharmacotherapy 20100101

• Modafinil administration improves working memory in methamphetamine-dependent individuals who demonstrate baseline impairment.

  The American journal on addictions 20100101

• Can I tell you the truth? A comparative perspective on regulating off-label scientific and medical information.

  Yale journal of health policy, law, and ethics 20100101

• Modeling dose-response relationships of the effects of fesoterodine in patients with overactive bladder.

  BMC urology 20100101

• Do anticholinergics affect reaction time? A possible impact on the course of rehabilitation.

  NeuroRehabilitation 20100101

• Modafinil-induced orofacial dyskinesia in an elderly patient with refractory bipolar depression.

  The Journal of neuropsychiatry and clinical neurosciences 20100101

• HIV-infected former plasma donors in rural Central China: from infection to survival outcomes, 1985-2008.

  PloS one 20100101

• [Modafinil in psychiatric disorders: the promising state reconsidered].

  Tijdschrift voor psychiatrie 20100101

• Investigation of the eIF2alpha phosphorylation mechanism in response to proteasome inhibition in melanoma and breast cancer cells.

  Molekuliarnaia biologiia 20100101

• Pharmacokinetic study of modafinil in relation to gender and ethnicity in healthy young Chinese volunteers.

  Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20100101

• Cancers in the TREAT Asia HIV Observational Database (TAHOD): a retrospective analysis of risk factors.

  Journal of the International AIDS Society 20100101

• Determination of fesoterodine in pharmaceutical formulations by using liquid chromatography-tandem mass spectrometry.

  European journal of mass spectrometry (Chichester, England) 20100101

• Physician attitudes towards pharmacological cognitive enhancement: safety concerns are paramount.

  PloS one 20100101

• Trends in CD4 counts in HIV-infected patients with HIV viral load monitoring while on combination antiretroviral treatment: results from The TREAT Asia HIV Observational Database.

  BMC infectious diseases 20100101

• Pharmacological strategies for enhancing cognition in schizophrenia.

  Current topics in behavioral neurosciences 20100101

• [Overactive bladder in patients with infravesical obstruction caused by prostatic adenoma].

  Urologiia (Moscow, Russia : 1999) 20100101

• QCM-arrays for sensing terpenes in fresh and dried herbs via bio-mimetic MIP layers.

  Sensors (Basel, Switzerland) 20100101

• Chronic infusion of PCP via osmotic mini-pumps: a new rodent model of cognitive deficit in schizophrenia characterized by impaired attentional set-shifting (ID/ED) performance.

  Journal of neuroscience methods 20091215

• Modafinil improves functional outcomes in patients with residual excessive sleepiness associated with CPAP treatment.

  Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20091215

• Idiopathic hypersomnia: clinical features and response to treatment.

  Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20091215

• Asymmetric conjugate reductions of coumarins. A new route to tolterodine and related coumarin derivatives.

  Organic letters 20091203

• The solid-state photo-CIDNP effect.

  Photosynthesis research 20091201

• Modafinil reinstates a cocaine conditioned place preference following extinction in rats.

  Behavioural brain research 20091201

• Modafinil for attentional and psychomotor dysfunction in advanced cancer: a double-blind, randomised, cross-over trial.

  Palliative medicine 20091201

• Modafinil for clozapine-treated schizophrenia patients: a double-blind, placebo-controlled pilot trial.

  The Journal of clinical psychiatry 20091201

• Synthesis and pharmacological evaluation of SNC80 analogues with a bridged piperazine ring.

  ChemMedChem 20091201

• The role of dopaminergic agents in improving quality of life in major depressive disorder.

  Current psychiatry reports 20091201

• Fesoterodine for the treatment of overactive bladder.

  The Annals of pharmacotherapy 20091201

• Narcolepsy: clinical decision making for the primary care physician.

  Southern medical journal 20091201

• Modafinil and zolpidem use by emergency medicine residents.

  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20091201

• 3-Benzyl-7-chloro-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexa-hydro-1H-pyrrolo[3,4-b]quinoline.

  Acta crystallographica. Section E, Structure reports online 20091201

• 3-Benzyl-7-bromo-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexa-hydro-1H-pyrrolo[3,4-b]quinoline.

  Acta crystallographica. Section E, Structure reports online 20091201

• 4,4'-Bis(dimethyl-amino)benzhydryl phenyl sulfone.

  Acta crystallographica. Section E, Structure reports online 20091201

• Benzhydryl phenyl sulfone.

  Acta crystallographica. Section E, Structure reports online 20091201

• Phenolic and enolic hydroxyl groups in curcumin: which plays the major role in scavenging radicals?

  Journal of agricultural and food chemistry 20091125

• Controversial action of positive modulator of subtype 7 of metabotropic glutamate receptors AMN082 on cortical epileptic afterdischarges in immature rats.

  European journal of pharmacology 20091125

• Anticholinergic drug use for overactive bladder in Sweden: a nationwide pharmacoepidemiological study.

  International urogynecology journal and pelvic floor dysfunction 20091101

• [Follow-up at 24 months after treatment of overactive bladder with 0.2 % sodium chondroitin sulfate].

  Aktuelle Urologie 20091101

• Utility of nanosized microemulsion for transdermal delivery of tolterodine tartrate: ex-vivo permeation and in-vivo pharmacokinetic studies.

  Pharmaceutical research 20091101

• A TRbeta-selective agonist confers resistance to diet-induced obesity.

  The Journal of endocrinology 20091101

• Synthesis and evaluation of (S,S)-N,N'-bis-[3-(2,2',6,6'-tetramethylbenzhydryloxy)-2-hydroxy-propyl]-ethylenediamine (S2824) analogs with anti-tuberculosis activity.

  Bioorganic & medicinal chemistry letters 20091101

• The effects of tolterodine extended release and alfuzosin for the treatment of double-j stent-related symptoms.

  Journal of endourology 20091101

• Fatigue, countermeasures, and performance enhancement in resident physicians.

  Mayo Clinic proceedings 20091101

• Armodafinil for treatment of excessive sleepiness associated with shift work disorder: a randomized controlled study.

  Mayo Clinic proceedings 20091101

• [Clinical efficacy of tolterodine for patients with overactive bladder after insufficient efficacy by monotherapy with alpha1-adrenoceptor antagonist].

  Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20091101

• 1-Benzyl-6,8-dimethyl-4-phenyl-2-tosyl-1,2,3,3a,4,6,7,8,9,9b-deca-hydro-pyrrolo[3,4-c]pyrano[6,5-d]pyrimidine-7,9-dione.

  Acta crystallographica. Section E, Structure reports online 20091101

• 3-Benzyl-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexa-hydro-1H-pyrrolo[3,4-b]quinoline.

  Acta crystallographica. Section E, Structure reports online 20091101

• 3-Benzyl-7-methyl-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexa-hydro-1H-pyrrolo[3,4-b]quinoline.

  Acta crystallographica. Section E, Structure reports online 20091101

• 3-Benzyl-7-meth-oxy-9-phenyl-2-tosyl-2,3,3a,4,9,9a-hexa-hydro-1H-pyrrolo[3,4-b]quinoline.

  Acta crystallographica. Section E, Structure reports online 20091101

• Synergistic neuroprotective effects of C3a and C5a receptor blockade following intracerebral hemorrhage.

  Brain research 20091028

• An on-line normal-phase high performance liquid chromatography method for the rapid detection of radical scavengers in non-polar food matrixes.

  Journal of chromatography. A 20091023

• Disease mongering and excessive daytime sleepiness.

  American family physician 20091015

• In search for tuneable intramolecular intermetallic interactions in polynuclear lanthanide complexes.

  Dalton transactions (Cambridge, England : 2003) 20091007

• Suppression of common-ion return by amines: a method to measure rates of fast S(N)1 reactions.

  The Journal of organic chemistry 20091002

• Modafinil in the treatment of debilitating fatigue in primary biliary cirrhosis: a clinical experience.

  Digestive diseases and sciences 20091001

• The selective metabotropic glutamate receptor 7 allosteric agonist AMN082 inhibits inflammatory pain-induced and incision-induced hypersensitivity in rat.

  Behavioural pharmacology 20091001

• Editorial comment.

  The Journal of urology 20091001

• Editorial comment.

  The Journal of urology 20091001

• Editorial comment.

  The Journal of urology 20091001

• Double anticholinergic therapy for refractory overactive bladder.

  The Journal of urology 20091001

• Comparing the stimulant effects of the H1-antagonist fexofenadine with 2 psychostimulants, modafinil and methylphenidate.

  Journal of clinical psychopharmacology 20091001

• Open-label pilot study of modafinil for methamphetamine dependence.

  Journal of clinical psychopharmacology 20091001

• Modafinil and γ-hydroxybutyrate have sleep state-specific pharmacological actions on hypocretin-1 physiology in a primate model of human sleep.

  Behavioural pharmacology 20091001

• Turbocharging the brain.

  Scientific American 20091001

• Current challenges in viral hepatitis, antimicrobial resistance and the influenza pandemic.

  Expert review of anti-infective therapy 20091001

• Secondary metabolites from the liverwort Ptilidium pulcherrimum.

  Natural product communications 20091001

• Organocatalytic activity of cinchona alkaloids: which nitrogen is more nucleophilic?

  The Journal of organic chemistry 20090918

• Tantalum clusters supported on silica-alumina: influence of support composition and chemistry on cluster structure.

  Langmuir : the ACS journal of surfaces and colloids 20090915

• Long-term treatment with sergliflozin etabonate improves disturbed glucose metabolism in KK-A(y) mice.

  European journal of pharmacology 20090915

• The functional Val158Met polymorphism of COMT predicts interindividual differences in brain alpha oscillations in young men.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090902

• Tolterodine treatment improves storage symptoms suggestive of overactive bladder in men treated with alpha-blockers.

  European urology 20090901

• Editorial comment on: Tolterodine treatment improves storage symptoms suggestive of overactive bladder in men treated with alpha-blockers.

  European urology 20090901

• Editorial comment on: Tolterodine treatment improves storage symptoms suggestive of overactive bladder in men treated with alpha-blockers.

  European urology 20090901

• Modafinil improves information processing speed and increases energetic resources for orientation of attention in narcoleptics: double-blind, placebo-controlled ERP studies with low-resolution brain electromagnetic tomography (LORETA).

  Sleep medicine 20090901

• Modafinil for the treatment of cocaine dependence.

  Drug and alcohol dependence 20090901

• Effects of tolterodine ER on patient-reported outcomes in sexually active women with overactive bladder and urgency urinary incontinence.

  Current medical research and opinion 20090901

• Randomized trial of percutaneous tibial nerve stimulation versus extended-release tolterodine: results from the overactive bladder innovative therapy trial.

  The Journal of urology 20090901

• The nightly administration of sodium oxybate results in significant reduction in the nocturnal sleep disruption of patients with narcolepsy.

  Sleep medicine 20090901

• Tolterodine extended-release for overactive bladder.

  Expert opinion on pharmacotherapy 20090901

• Armodafinil.

  CNS drugs 20090901

• Influence of age, gender, and race on pharmacokinetics, pharmacodynamics, and safety of fesoterodine.

  International journal of clinical pharmacology and therapeutics 20090901

• Clinical and epidemiologic characteristics of 3 early cases of influenza A pandemic (H1N1) 2009 virus infection, People's Republic of China, 2009.

  Emerging infectious diseases 20090901

• Nuvigil.

  JAAPA : official journal of the American Academy of Physician Assistants 20090901

• Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin.

  Journal of molecular biology 20090821

• Can one predict changes from S(N)1 to S(N)2 mechanisms?

  Journal of the American Chemical Society 20090819

• A randomized, double-blind and placebo-controlled trial of modafinil in children and adolescents with attention deficit and hyperactivity disorder.

  Psychiatry research 20090815

• Unsuccessful suicide attempt of a 15 year old adolescent with ingestion of 5000 mg modafinil.

  Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20090815

• Improved tricyclic inhibitors of trypanothione reductase by screening and chemical synthesis.

  ChemMedChem 20090803

• Effects of the atypical stimulant modafinil on a brief gambling episode in pathological gamblers with high vs. low impulsivity.

  Journal of psychopharmacology (Oxford, England) 20090801

• Enantioselective separation and determination of adrafinil and modafinil on Chiralcel OJ-H column in rat serum and urine using solid-phase extraction followed by HPLC.

  Biomedical chromatography : BMC 20090801

• Dopamine D2High receptors stimulated by phencyclidines, lysergic acid diethylamide, salvinorin A, and modafinil.

  Synapse (New York, N.Y.) 20090801

• Hallucinations associated with modafinil treatment for narcolepsy.

  Journal of clinical psychopharmacology 20090801

• GABA(B) receptors, schizophrenia and sleep dysfunction: a review of the relationship and its potential clinical and therapeutic implications.

  CNS drugs 20090801

• Behavioural profile of selective ligands for mGlu7 and mGlu8 glutamate receptors in agonistic encounters between mice.

  Psicothema 20090801

• Tolterodine extended release is well tolerated in older subjects.

  International journal of clinical practice 20090801

• Fesoterodine for the treatment of overactive bladder.

  The Nurse practitioner 20090801

• Modafinil as a potential motion sickness countermeasure.

  Aviation, space, and environmental medicine 20090801

• Armodafinil for the treatment of excessive sleepiness.

  Aviation, space, and environmental medicine 20090801

• Neuroimaging of narcolepsy.

  CNS & neurological disorders drug targets 20090801

• Modafinil for the treatment of hypersomnia associated with myotonic muscular dystrophy in adults: a multicenter, prospective, randomized, double-blind, placebo-controlled, 4-week trial.

  Clinical therapeutics 20090801

• Management of sleep/wake cycles improves cognitive function in a transgenic mouse model of Huntington's disease.

  Brain research 20090707

• A multicomponent behavioural and drug intervention for nocturia in elderly men: rationale and pilot results.

  BJU international 20090701

• Depression-like deficits in rats improved by subchronic modafinil.

  Psychopharmacology 20090701

• Synthesis and biological characterization of (3R,4R)-4-(2-(benzhydryloxy)ethyl)-1-((R)-2-hydroxy-2-phenylethyl)-piperidin-3-ol and its stereoisomers for activity toward monoamine transporters.

  ChemMedChem 20090701

• Benzhydrylquinazolinediones: novel cytosolic phospholipase A2alpha inhibitors with improved physicochemical properties.

  Bioorganic & medicinal chemistry 20090701

• Efficacy and tolerability of fesoterodine in women with overactive bladder.

  International urogynecology journal and pelvic floor dysfunction 20090701

• Narcolepsy: action of two gamma-aminobutyric acid type B agonists, baclofen and sodium oxybate.

  Pediatric neurology 20090701

• [Combination of tolterodine and tamsulosin for benign prostatic hyperplasia].

  Zhonghua nan ke xue = National journal of andrology 20090701

• Regiospecific syntheses of 6alpha-(1R-Hydroxyoctyl)penicillanic acid and 6beta-(1R-hydroxyoctyl)penicillanic acid as mechanistic probes of class D beta-lactamases.

  Organic letters 20090618

• Methods for preparing metal ion photocages: application to the synthesis of crowncast.

  Organic letters 20090618

• The effect of modafinil on cognitive function in breast cancer survivors.

  Cancer 20090615

• Discovery of diphenylmethane analogs as anti-bovine diarrhea viral agents.

  Bioorganic & medicinal chemistry letters 20090615

• Enantioselective synthesis of (R)-tolterodine via CuH-catalyzed asymmetric conjugate reduction.

  The Journal of organic chemistry 20090605

• Transdermal delivery of tolterodine by O-acylmenthol: In vitro/in vivo correlation.

  International journal of pharmaceutics 20090605

• Modafinil treatment of amphetamine abuse in adult ADHD.

  Journal of psychopharmacology (Oxford, England) 20090601

• Modafinil normalized hyperreflexia after spinal transection in adult rats.

  Spinal cord 20090601

• Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090601

• How to keep the brain awake? The complex molecular pharmacogenetics of wake promotion.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090601

• Psychological health in central hypersomnias: the French Harmony study.

  Journal of neurology, neurosurgery, and psychiatry 20090601

• Decrease of urinary nerve growth factor levels after antimuscarinic therapy in patients with overactive bladder.

  BJU international 20090601

• Modafinil for the treatment of fatigue in lung cancer: a pilot study.

  Palliative medicine 20090601

• Complement factors C3a and C5a have distinct hemodynamic effects in the rat.

  International immunopharmacology 20090601

• Evaluation of drug-drug interactions with fesoterodine.

  European journal of clinical pharmacology 20090601

• Combined effects of behavioral intervention and tolterodine in patients dissatisfied with overactive bladder medication.

  The Journal of urology 20090601

• Influence of food on the pharmacokinetic profile of fesoterodine.

  International journal of clinical pharmacology and therapeutics 20090601

• New drug information: Toviaz.

  JAAPA : official journal of the American Academy of Physician Assistants 20090601

• Fesoterodine (toviaz) for overactive bladder.

  The Medical letter on drugs and therapeutics 20090504

• Evidence for the involvement of dopamine transporters in behavioral stimulant effects of modafinil.

  The Journal of pharmacology and experimental therapeutics 20090501

• Armodafinil promotes wakefulness and activates Fos in rat brain.

  Pharmacology, biochemistry, and behavior 20090501

• LC-MS of novel narcoepileptics and related substances.

  Journal of separation science 20090501

• Differential effects of acute and repeat dosing with the H3 antagonist GSK189254 on the sleep-wake cycle and narcoleptic episodes in Ox-/- mice.

  British journal of pharmacology 20090501

• A pilot study evaluating the safety and efficacy of modafinal for cancer-related fatigue.

  Journal of palliative medicine 20090501

• Specificity of direct transition from wake to REM sleep in orexin/ataxin-3 transgenic narcoleptic mice.

  Experimental neurology 20090501

• Narcolepsy--master of disguise: evidence-based recommendations for management.

  Postgraduate medicine 20090501

• Conformational effects on excitonic interactions in a prototypical H-bonded bichromophore: bis(2-hydroxyphenyl)methane.

  The journal of physical chemistry. A 20090430

• Conformational isomerization and collisional cooling dynamics of bis(2-hydroxyphenyl)methane.

  The journal of physical chemistry. A 20090430

• Discovery of novel 1-azoniabicyclo[2.2.2]octane muscarinic acetylcholine receptor antagonists.

  Journal of medicinal chemistry 20090423

• Peptide cyclization and cyclodimerization by Cu(I)-mediated azide-alkyne cycloaddition.

  The Journal of organic chemistry 20090417

• Heat shock protein inhibitors, 17-DMAG and KNK437, enhance arsenic trioxide-induced mitotic apoptosis.

  Toxicology and applied pharmacology 20090415

• Treatment of sleep disorders after traumatic brain injury.

  Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20090415

• An exploration of the effect of modafinil on olanzapine associated weight gain in normal human subjects.

  Biological psychiatry 20090401

• Continued symptom improvement in sexually active women with overactive bladder and urgency urinary incontinence treated with tolterodine ER for 6 months.

  International urogynecology journal and pelvic floor dysfunction 20090401

• Is there a role for psychostimulants in old age depression and apathy?

  International psychogeriatrics 20090401

• Assessment of the effects of renal impairment on the pharmacokinetic profile of fesoterodine.

  Journal of clinical pharmacology 20090401

• Determination of tolterodine and its 5-hydroxymethyl metabolite in human plasma by hydrophilic interaction liquid chromatography-tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090401

• Does urodynamic verification of overactive bladder determine treatment success? Results from a randomized placebo-controlled study.

  BJU international 20090401

• Efficacy and safety of modafinil in the treatment of cancer-related fatigue.

  The Annals of pharmacotherapy 20090401

• Modafinil and memory: effects of modafinil on Morris water maze learning and Pavlovian fear conditioning.

  Behavioral neuroscience 20090401

• Effects of flexible-dose fesoterodine on overactive bladder symptoms and treatment satisfaction: an open-label study.

  International journal of clinical practice 20090401

• Modafinil effects in multiple sclerosis patients with fatigue.

  Journal of neurology 20090401

• Biodegradation of bisphenol A, bisphenol F and bisphenol S in seawater.

  International journal of environmental research and public health 20090401

• 3-(4-Methoxy-benz-yl)-2-methyl-1-phenyl-sulfonyl-1H-indole.

  Acta crystallographica. Section E, Structure reports online 20090401

• Bis[2-(3-bromo-prop-oxy)-5-methyl-phen-yl]methane.

  Acta crystallographica. Section E, Structure reports online 20090401

• Effects of modafinil on dopamine and dopamine transporters in the male human brain: clinical implications.

  JAMA 20090318

• The pharmacokinetic profile of fesoterodine: similarities and differences to tolterodine.

  Swiss medical weekly 20090307

• Dopamine D1 and D2 receptor family contributions to modafinil-induced wakefulness.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090304

• Effects of psychostimulants on alertness and spatial bias in healthy participants.

  Journal of cognitive neuroscience 20090301

• Editorial comment on: Is there a synergistic effect of topical oestrogens when administered with antimuscarinics in the treatment of symptomatic detrusor overactivity?

  European urology 20090301

• Editorial comment on: Is there a synergistic effect of topical oestrogens when administered with antimuscarinics in the treatment of symptomatic detrusor overactivity?

  European urology 20090301

• Is there a synergistic effect of topical oestrogens when administered with antimuscarinics in the treatment of symptomatic detrusor overactivity?

  European urology 20090301

• Comparison of receptor binding characteristics of commonly used muscarinic antagonists in human bladder detrusor and mucosa.

  The Journal of pharmacology and experimental therapeutics 20090301

• Pharmacogenetics of modafinil after sleep loss: catechol-O-methyltransferase genotype modulates waking functions but not recovery sleep.

  Clinical pharmacology and therapeutics 20090301

• C3a mediates epithelial-to-mesenchymal transition in proteinuric nephropathy.

  Journal of the American Society of Nephrology : JASN 20090301

• A multi-drug intoxication fatality involving Xyrem (GHB).

  Journal of forensic sciences 20090301

• Modafinil treatment of fatigue in patients with ALS: a placebo-controlled study.

  Muscle & nerve 20090301

• In vivo and in vitro pharmacological characterization of SVT-40776, a novel M3 muscarinic receptor antagonist, for the treatment of overactive bladder.

  British journal of pharmacology 20090301

• Augmentation of dopaminergic agents for major depressive disorder.

  The Journal of clinical psychiatry 20090301

• Optimal treatment of obstructive sleep apnea and excessive sleepiness.

  Advances in therapy 20090301

• Fesoterodine: a new agent for treating overactive bladder.

  The American journal of managed care 20090301

• Solifenacin in the treatment of overactive bladder syndrome in Italian patients: pharmacoeconomic evaluation.

  Journal of medical economics 20090301

• Palladium-catalyzed cross-coupling reactions of benzyl indium reagents with aryl iodides.

  The Journal of organic chemistry 20090206

• Editorial comment on: Tolterodine extended release with or without tamsulosin in men with lower urinary tract symptoms including overactive bladder symptoms: effects of prostate size.

  European urology 20090201

• Tolterodine extended release with or without tamsulosin in men with lower urinary tract symptoms including overactive bladder symptoms: effects of prostate size.

  European urology 20090201

• Editorial comment on: Tolterodine extended release with or without tamsulosin in men with lower urinary tract symptoms including overactive bladder symptoms: effects of prostate size.

  European urology 20090201

• Toxicity from modafinil ingestion.

  Clinical toxicology (Philadelphia, Pa.) 20090201

• Alkaline reforming of brominated fire-retardant plastics: fate of bromine and antimony.

  Chemosphere 20090201

• Thyroid hormone receptor subtype specificity for hormone-dependent neurogenesis in Xenopus laevis.

  Developmental biology 20090201

• Modafinil in the media: metaphors, medicalisation and the body.

  Social science & medicine (1982) 20090201

• Discovery and SAR of benzyl phenyl ethers as inhibitors of bacterial phenylalanyl-tRNA synthetase.

  Bioorganic & medicinal chemistry letters 20090201

• A double-blind, placebo-controlled trial of modafinil (200 mg/day) for methamphetamine dependence.

  Addiction (Abingdon, England) 20090201

• The long road to pharmacotherapies for stimulant dependence.

  Addiction (Abingdon, England) 20090201

• [Multinational clinical trial in Japan and Korea on detrusitol].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20090201

• Sustaining executive functions during sleep deprivation: A comparison of caffeine, dextroamphetamine, and modafinil.

  Sleep 20090201

• Genotoxic and endocrine activities of bis(hydroxyphenyl)methane (bisphenol F) and its derivatives in the HepG2 cell line.

  Toxicology 20090108

• Comparison of haloperidol, risperidone, sertindole, and modafinil to reverse an attentional set-shifting impairment following subchronic PCP administration in the rat--a back translational study.

  Psychopharmacology 20090101

• Determination of reactions between free radicals and selected Chilean wines and transition metals by ESR and UV-vis technique.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090101

• Resonance light scattering study on the interaction of benproperine phosphate with eriochrome blue black R in the presence of sodium dodecylbenzene sulphonate and its analytical application.

  Luminescence : the journal of biological and chemical luminescence 20090101

• Acanthoscurrin fragment 101-132: total synthesis at 60 degrees C of a novel difficult sequence.

  Biopolymers 20090101

• Modafinil as an adjunctive treatment of sedation, negative symptoms, and cognition in schizophrenia: a critical review.

  The Journal of clinical psychiatry 20090101

• Modafinil improves rapid shifts of attention.

  Psychopharmacology 20090101

• Dual labeling of biomolecules by using click chemistry: a sequential approach.

  Angewandte Chemie (International ed. in English) 20090101

• Randomized comparison of tolterodine with vaginal estrogen cream versus tolterodine alone for the treatment of postmenopausal women with overactive bladder syndrome.

  Neurourology and urodynamics 20090101

• Anti human immunodeficiency virus-1 (HIV-1) agents 1. Discovery of benzyl phenyl ethers as new HIV-1 inhibitors in vitro.

  Chemical & pharmaceutical bulletin 20090101

• Hemodynamic and cardiac neurotransmitter-releasing effects in conscious dogs of attention- and wake-promoting agents: a comparison of d-amphetamine, atomoxetine, modafinil, and a novel quinazolinone H3 inverse agonist.

  Journal of cardiovascular pharmacology 20090101

• Pharmacokinetic profile of armodafinil in healthy subjects: pooled analysis of data from three randomized studies.

  Clinical drug investigation 20090101

• Provigil (modafinil) plus cognitive behavioral therapy for methamphetamine use in HIV+ gay men: a pilot study.

  The American journal of drug and alcohol abuse 20090101

• Synthesis and antimicrobial activity of 1-benzhydryl-sulfonyl-4-(3-(piperidin-4-yl) propyl)piperidine derivatives against pathogens of Lycopersicon esculentum: a structure-activity evaluation study.

  Archives of pharmacal research 20090101

• Precipitating pharmakologies and capital entrapments: narcolepsy and the strange cases of Provigil and Xyrem.

  Medical anthropology 20090101

• Correlations among improvements in urgency urinary incontinence, health-related quality of life, and perception of bladder-related problems in incontinent subjects with overactive bladder treated with tolterodine or placebo.

  Health and quality of life outcomes 20090101

• Synthesis and pharmacological properties of new derivatives of 4-alkoxy-6-methyl-1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diones.

  Acta poloniae pharmaceutica 20090101

• Effect of phorbol esters on the macrophage-mediated biodegradation of polyurethanes via protein kinase C activation and other pathways.

  Journal of biomaterials science. Polymer edition 20090101

• Solid-phase synthesis of chiral bicyclic guanidinium oligomers.

  Journal of combinatorial chemistry 20090101

• Ratiometric Ca+2 measurement in human recombinant muscarinic receptor subtypes using the Flexstation scanning fluorometer.

  Journal of receptor and signal transduction research 20090101

• New drugs: milnacipran hydrochloride, fesoterodine fumarate, and silodosin.

  Journal of the American Pharmacists Association : JAPhA 20090101

• Structural antitumoral activity relationships of synthetic chalcones.

  International journal of molecular sciences 20090101

• [Jointed estrogenic activities of bisphenol A and three of its analogs].

  Huan jing ke xue= Huanjing kexue 20090101

• Diary and patient-reported outcomes in patients with severe overactive bladder switching from tolterodine extended release 4 mg/day to solifenacin treatment: An open-label, flexible-dosing, multicentre study.

  Clinical drug investigation 20090101

• Risk and prognostic significance of tuberculosis in patients from The TREAT Asia HIV Observational Database.

  BMC infectious diseases 20090101

• Cost-effectiveness analysis of solifenacin flexible dosing in patients with overactive bladder symptoms in four Nordic countries.

  Acta obstetricia et gynecologica Scandinavica 20090101

• Fesoterodine.

  Drugs 20090101

• Identification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1.

  PloS one 20090101

• The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly.

  Clinical interventions in aging 20090101

• Using modafinil to treat fatigue in Parkinson disease: a double-blind, placebo-controlled pilot study.

  Clinical neuropharmacology 20090101

• [Structure-functional analysis of interactions of terminal deoxynucleotidyl transferase with new non-nucleoside substrates].

  Bioorganicheskaia khimiia 20090101

• Comparison of steady-state plasma concentrations of armodafinil and modafinil late in the day following morning administration: post hoc analysis of two randomized, double-blind, placebo-controlled, multiple-dose studies in healthy male subjects.

  Clinical drug investigation 20090101

• Armodafinil and modafinil have substantially different pharmacokinetic profiles despite having the same terminal half-lives: analysis of data from three randomized, single-dose, pharmacokinetic studies.

  Clinical drug investigation 20090101

• Effect of modafinil on subjective fatigue in multiple sclerosis and stroke patients.

  European neurology 20090101

• Narcolepsy and psychotic states--a case report.

  The Israel journal of psychiatry and related sciences 20090101

• The design and development of fesoterodine as a prodrug of 5-hydroxymethyl tolterodine (5-HMT), the active metabolite of tolterodine.

  Current medicinal chemistry 20090101

• A novel enediynyl peptide inhibitor of furin that blocks processing of proPDGF-A, B and proVEGF-C.

  PloS one 20090101

• Reverse-phase, high performance liquid chromatographic method for the determination of tolterodine tartrate in routine quality control samples.

  PDA journal of pharmaceutical science and technology 20090101

• Synthesis and Biological Evaluation of beta-Aroylpropionic acid based 1,3,4-Oxadiazoles.

  Indian journal of pharmaceutical sciences 20090101

• Phytoremediation of benzophenone and bisphenol a by glycosylation with immobilized plant cells.

  Environmental health insights 20090101

• Bioremediation of Bisphenol A and Benzophenone by Glycosylation with Immobilized Marine Microalga Pavlova sp.

  Environmental health insights 20090101

• Ebastine in the light of CONGA recommendations for the development of third-generation antihistamines.

  Journal of asthma and allergy 20090101

• Diethyl 2-[(2-benzyl-1-phenyl-sulfonyl-1H-indol-3-yl)methyl-ene]malonate.

  Acta crystallographica. Section E, Structure reports online 20090101

• Biomimetic Yeast Cell Typing-Application of QCMs.

  Sensors (Basel, Switzerland) 20090101

• Conception, pregnancy, delivery, and breastfeeding in a narcoleptic patient with cataplexy.

  Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20081215

• Rotationally resolved studies of S0 and the exciton coupled S1/S2 origin regions of diphenylmethane and the d(12) isotopologue.

  The Journal of chemical physics 20081214

• Modafinil shifts human locus coeruleus to low-tonic, high-phasic activity during functional MRI.

  Science (New York, N.Y.) 20081212

• [Disorders in the regulation of alertness. Drowsy white rock climbing and wide awake at night].

  MMW Fortschritte der Medizin 20081211

• [Falling sleep inopportunely: treatment of narcolepsy].

  MMW Fortschritte der Medizin 20081211

• Oxidative reactivity difference among the metal oxo and metal hydroxo moieties: pH dependent hydrogen abstraction by a manganese(IV) complex having two hydroxide ligands.

  Journal of the American Chemical Society 20081203

• Behavioral responses of dopamine beta-hydroxylase knockout mice to modafinil suggest a dual noradrenergic-dopaminergic mechanism of action.

  Pharmacology, biochemistry, and behavior 20081201

• Tolterodine immediate release improves sexual function in women with overactive bladder.

  The journal of sexual medicine 20081201

• Differential pharmacological effects of antimuscarinic drugs on heart rate: a randomized, placebo-controlled, double-blind, crossover study with tolterodine and darifenacin in healthy participants > or = 50 years.

  Journal of cardiovascular pharmacology and therapeutics 20081201

• Efficient synthesis and biological evaluation of two modafinil analogues.

  Bioorganic & medicinal chemistry 20081201

• Adjunctive use of modafinil in bipolar patients: just another stimulant or not?

  Current psychiatry reports 20081201

• Long-term efficacy and safety of tolterodine in children with neurogenic detrusor overactivity.

  Journal of pediatric urology 20081201

• Toviaz approved for overactive bladder.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20081201

• DNA-dependent protein kinase is involved in heat shock protein-mediated accumulation of hypoxia-inducible factor-1alpha in hypoxic preconditioned HepG2 cells.

  The FEBS journal 20081201

• Effects of tolterodine extended release on patient perception of bladder condition and overactive bladder symptoms*.

  Current medical research and opinion 20081201

• Effects of modafinil on simulator driving and self-assessment of driving following sleep deprivation.

  Human psychopharmacology 20081201

• Microsomal antiestrogen-binding site ligands induce growth control and differentiation of human breast cancer cells through the modulation of cholesterol metabolism.

  Molecular cancer therapeutics 20081201

• 1,1-Bis(3'-indolyl)-1-(p-chlorophenyl)methane activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth.

  Molecular cancer therapeutics 20081201

• Gaps that wake you up.

  Sleep 20081201

• Modafinil increases arousal determined by P13 potential amplitude: an effect blocked by gap junction antagonists.

  Sleep 20081201

• Fatigue: an overview.

  American family physician 20081115

• The effect of modafinil following acute CPAP withdrawal: a preliminary study.

  Sleep & breathing = Schlaf & Atmung 20081101

• Pediatric narcolepsy.

  Brain & development 20081101

• Extended-release tolterodine with or without tamsulosin in men with lower urinary tract symptoms and overactive bladder: effects on urinary symptoms assessed by the International Prostate Symptom Score.

  BJU international 20081101

• A placebo-controlled trial of modafinil for nicotine dependence.

  Drug and alcohol dependence 20081101

• Nonselective suppression of operant ethanol and sucrose self-administration by the mGluR7 positive allosteric modulator AMN082.

  Pharmacology, biochemistry, and behavior 20081101

• Comparison of fesoterodine and tolterodine in patients with overactive bladder.

  BJU international 20081101

• Efficacy of tolterodine on overactive bladder symptoms and sexual and emotional quality of life in sexually active women.

  International urogynecology journal and pelvic floor dysfunction 20081101

• Nocturia, nocturnal incontinence prevalence, and response to anticholinergic and behavioral therapy.

  International urogynecology journal and pelvic floor dysfunction 20081101

• Effects of serum PSA on efficacy of tolterodine extended release with or without tamsulosin in men with LUTS, including OAB.

  Urology 20081101

• Sex differences in cognitive estimation during sleep deprivation: effects of stimulant countermeasures.

  The International journal of neuroscience 20081101

• The effects of reformulation: improved therapeutic index.

  Current urology reports 20081101

• Combination therapy with desmopressin and an anticholinergic medication for nonresponders to desmopressin for monosymptomatic nocturnal enuresis: a randomized, double-blind, placebo-controlled trial.

  Pediatrics 20081101

• Pharmacokinetic profile of fesoterodine.

  International journal of clinical pharmacology and therapeutics 20081101

• Effects of modafinil and sleep loss on physiological parameters.

  Military medicine 20081101

• mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity.

  Molecular psychiatry 20081001

• Editorial comment on: Urinary incontinence at orgasm: relation to detrusor overactivity and treatment efficacy.

  European urology 20081001

• Editorial comment on: Urinary incontinence at orgasm: relation to detrusor overactivity and treatment efficacy.

  European urology 20081001

• Urinary incontinence at orgasm: relation to detrusor overactivity and treatment efficacy.

  European urology 20081001

• Symptoms and sleep patterns during inpatient treatment of methamphetamine withdrawal: a comparison of mirtazapine and modafinil with treatment as usual.

  Journal of substance abuse treatment 20081001

• Human urine with solifenacin intake but not tolterodine or darifenacin intake blocks detrusor overactivity.

  International urogynecology journal and pelvic floor dysfunction 20081001

• Modafinil decreases food intake in humans subjected to simulated shift work.

  Pharmacology, biochemistry, and behavior 20081001

• A systematic review and meta-analysis of randomized controlled trials with antimuscarinic drugs for overactive bladder.

  European urology 20081001

• Biotransformation of bisphenol F by human and rat liver subcellular fractions.

  Toxicology in vitro : an international journal published in association with BIBRA 20081001

• Comparison of the effect of heat shock factor inhibitor, KNK437, on heat shock- and chemical stress-induced hsp30 gene expression in Xenopus laevis A6 cells.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20081001

• Structural development of benzhydrol-type 1'-acetoxychavicol acetate (ACA) analogs as human leukemia cell-growth inhibitors based on quantitative structure-activity relationship (QSAR) analysis.

  Chemical & pharmaceutical bulletin 20081001

• Pharmacologic treatment options for cancer-related fatigue: current state of clinical research.

  Clinical journal of oncology nursing 20081001

• Serum ferritin and transferrin levels as serologic markers of methylene diphenyl diisocyanate-induced occupational asthma.

  The Journal of allergy and clinical immunology 20081001

• Efficacy of solifenacin in patients previously treated with tolterodine extended release 4 mg: results of a 12-week, multicenter, open-label, flexible-dose study.

  Clinical therapeutics 20081001

• State-specific studies of internal mixing in a prototypical flexible bichromophore: Diphenylmethane.

  The Journal of chemical physics 20080921

• Regulation of synaptic efficacy in hypocretin/orexin-containing neurons by melanin concentrating hormone in the lateral hypothalamus.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080910

• Waking up to sleepiness: Modafinil, the media and the pharmaceuticalisation of everyday/night life.

  Sociology of health & illness 20080901

• Effects of dextroamphetamine, caffeine and modafinil on psychomotor vigilance test performance after 44 h of continuous wakefulness.

  Journal of sleep research 20080901

• AMN082, an allosteric mGluR7 agonist that inhibits afferent glutamatergic transmission in rat basolateral amygdala.

  Neuropharmacology 20080901

• Group III mGluR7 and mGluR8 in the amygdala differentially modulate nocifensive and affective pain behaviors.

  Neuropharmacology 20080901

• How many drugs for LUTS due to BPH are too many?

  The Journal of urology 20080901

• Effect of tolterodine extended release with or without tamsulosin on measures of urgency and patient reported outcomes in men with lower urinary tract symptoms.

  The Journal of urology 20080901

• Tolterodine extended release is efficacious in continent and incontinent subjects with overactive bladder.

  Urology 20080901

• Selective activation of metabotropic G-protein-coupled glutamate 7 receptor elicits anxiolytic-like effects in mice by modulating GABAergic neurotransmission.

  Behavioural pharmacology 20080901

• Frequency, characterisation and therapies of fatigue after stroke.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20080901

• Synthesis and evaluation of 1-benzhydryl-sulfonyl-piperazine derivatives as inhibitors of tumor growth and tumor angiogenesis of mouse ehrlich ascites tumor in vivo.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20080901

• Restoration of risk-propensity during sleep deprivation: caffeine, dextroamphetamine, and modafinil.

  Aviation, space, and environmental medicine 20080901

• Iterative molecular assembly based on the cation-pool method. Convergent synthesis of dendritic molecules.

  Journal of the American Chemical Society 20080820

• No rest for fatigue researchers.

  Journal of the National Cancer Institute 20080820

• Dopaminergic D1 and D2 receptors are essential for the arousal effect of modafinil.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080820

• Behavioral therapy to enable women with urge incontinence to discontinue drug treatment: a randomized trial.

  Annals of internal medicine 20080805

• Spectroscopic characterization of the 1-substituted 3,3-diphenyl-4-(2'-hydroxyphenyl)azetidin-2-ones: application of (13)C NMR, (1)H-(13)C COSY NMR and mass spectroscopy.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080801

• Use of large-scale chromatography in the preparation of armodafinil.

  Chirality 20080801

• Day case general anaesthesia in a patient with narcolepsy.

  Anaesthesia 20080801

• A cost-utility analysis of once daily solifenacin compared to tolterodine in the treatment of overactive bladder syndrome.

  Current medical research and opinion 20080801

• New picropodophyllin analogs via palladium-catalyzed allylic alkylation-Hiyama cross-coupling sequences.

  The Journal of organic chemistry 20080801

• Pharmacokinetics and tolerability of modafinil tablets in Chinese subjects.

  Journal of clinical pharmacy and therapeutics 20080801

• Management of patients with obstructive sleep apnea.

  The Journal of family practice 20080801

• Acceleration tolerance at night with acute fatigue and stimulants.

  Aviation, space, and environmental medicine 20080801

• Modafinil-induced psychosis.

  Internal medicine journal 20080801

• 4-Benzhydryl-1-cinnamylpiperazin-1-ium nitrate.

  Acta crystallographica. Section E, Structure reports online 20080801

• Cancer investigators make strides in improving patients' quality of life.

  JAMA 20080723

• Amygdaloid metabotropic glutamate receptor subtype 7 is involved in the acquisition of conditioned fear.

  Neuroreport 20080716

• Ligands to the (IRAP)/AT4 receptor encompassing a 4-hydroxydiphenylmethane scaffold replacing Tyr2.

  Bioorganic & medicinal chemistry 20080715

• Effect of tolterodine on sleep structure modulated by CYP2D6 genotype.

  Sleep medicine 20080701

• Heat shock protein 70 of Naegleria fowleri is important factor for proliferation and in vitro cytotoxicity.

  Parasitology research 20080701

• The effects of modafinil on mood and cognition in Huntington's disease.

  Psychopharmacology 20080701

• Impact of fesoterodine on quality of life: pooled data from two randomized trials.

  BJU international 20080701

• Fesoterodine: a novel muscarinic receptor antagonist for the treatment of overactive bladder syndrome.

  Expert opinion on pharmacotherapy 20080701

• Impact of modafinil on spasticity reduction and quality of life in children with CP.

  Developmental medicine and child neurology 20080701

• 2-Amino-N-(2-benz-yloxy-3-methoxy-benzyl-idene)aniline.

  Acta crystallographica. Section E, Structure reports online 20080701

• Carbene proton attachment energies: theoretical study.

  The journal of physical chemistry. A 20080612

• Modafinil: a review of neurochemical actions and effects on cognition.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080601

• In vivo characterization of muscarinic receptors in peripheral tissues: evaluation of bladder selectivity of anticholinergic agents to treat overactive bladder.

  Naunyn-Schmiedeberg's archives of pharmacology 20080601

• Effect of tolterodine on gastrointestinal transit and bowel habits in healthy subjects.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20080601

• Impact of solifenacin on resource utilization, work productivity and health utility in overactive bladder patients switching from tolterodine ER.

  Current medical research and opinion 20080601

• Relationships between improvements in symptoms and patient assessments of bladder condition, symptom bother and health-related quality of life in patients with overactive bladder treated with tolterodine.

  International journal of clinical practice 20080601

• The search for medications to treat stimulant dependence.

  Addiction science & clinical practice 20080601

• Hyponatremia associated with tolterodine therapy.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080601

• Effect of modafinil on cerebral blood flow in narcolepsy patients.

  Sleep 20080601

• Mechanism of selenium-induced inhibition of arsenic-enhanced UVR carcinogenesis in mice.

  Environmental health perspectives 20080601

• Armodafinil for excessive daytime sleepiness.

  Drugs of today (Barcelona, Spain : 1998) 20080601

• Modafinil: a useful medication for cocaine addiction? Review of the evidence from neuropharmacological, experimental and clinical studies.

  Current drug abuse reviews 20080601

• Prucalopride: the evidence for its use in the treatment of chronic constipation.

  Core evidence 20080601

• 2-O-Benzhydryl-3,4-(S)-O-benzyl-idene-d-xylono-1,4-lactone.

  Acta crystallographica. Section E, Structure reports online 20080601

• 4-{[1-(4-Ethoxy-phen-yl)-5-methyl-1H-1,2,3-triazol-4-yl]diphenyl-meth-yl}morpholine.

  Acta crystallographica. Section E, Structure reports online 20080601

• 2-Methyl-1,1,3,3-tetra-phenyl-propan-2-ol.

  Acta crystallographica. Section E, Structure reports online 20080601

• Influence of solvent on carbene intersystem crossing rates.

  Journal of the American Chemical Society 20080521

• Promoting of wakefulness by administrations of modafinil into anterior hypothalamus and into the pedunculopontine tegmental nucleus in rats.

  Neuroscience letters 20080509

• Modafinil modulates GABA-activated currents in rat hippocampal pyramidal neurons.

  Brain research 20080507

• Efficacy of tolterodine in relation to different urodynamic findings of detrusor overactivity.

  International urogynecology journal and pelvic floor dysfunction 20080501

• C3a receptor modulation of granulocyte infiltration after murine focal cerebral ischemia is reperfusion dependent.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20080501

• Therapeutic effects of Delta9-THC and modafinil in a marmoset Parkinson model.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20080501

• Effective treatment of neurogenic detrusor dysfunction by combined high-dosed antimuscarinics without increased side-effects.

  European urology 20080501

• Fesoterodine dose response in subjects with overactive bladder syndrome.

  Urology 20080501

• The principles of agonist pharmacotherapy for psychostimulant dependence.

  Drug and alcohol review 20080501

• Development of thermotolerance requires interaction between polymerase-beta and heat shock proteins.

  Cancer science 20080501

• Dual use of bladder anticholinergics and cholinesterase inhibitors: long-term functional and cognitive outcomes.

  Journal of the American Geriatrics Society 20080501

• Commentary on tolterodine for men with benign prostatic hyperplasia and lower urinary tract symptoms.

  The Journal of urology 20080501

• Tolterodine for the treatment of overactive bladder.

  Expert opinion on pharmacotherapy 20080501

• Overactive bladder disease: the urge for better therapies.

  Journal of managed care pharmacy : JMCP 20080501

• A method for determination of the plasma levels of modafinil enantiomers, (+/-)-modafinic acid and modafinil sulphone by direct human plasma injection and bidimensional achiral-chiral chromatography.

  Journal of pharmaceutical and biomedical analysis 20080414

• Redox chemistry of the triplet complex (PNP)Co(I).

  Journal of the American Chemical Society 20080402

• Ultra short manic-like episodes after antidepressant augmentation with modafinil.

  Progress in neuro-psychopharmacology & biological psychiatry 20080401

• [Current pharmacotherapies and immunotherapy in cocaine addiction].

  Presse medicale (Paris, France : 1983) 20080401

• Pharmacological characterization of a novel investigational antimuscarinic drug, fesoterodine, in vitro and in vivo.

  BJU international 20080401

• Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity.

  Bioorganic & medicinal chemistry 20080401

• An inverse agonist of the histamine H(3) receptor improves wakefulness in narcolepsy: studies in orexin-/- mice and patients.

  Neurobiology of disease 20080401

• The effects of modafinil, caffeine, and dextroamphetamine on judgments of simple versus complex emotional expressions following sleep deprivation.

  The International journal of neuroscience 20080401

• Visual and coenesthetic hallucinations associated with modafinil.

  Journal of clinical psychopharmacology 20080401

• Clinical and immunologic findings of methylene diphenyl diisocyanate-induced occupational asthma in a car upholstery factory.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20080401

• Armodafinil: a new treatment for excessive sleepiness.

  Expert opinion on investigational drugs 20080401

• Enantioselective HPLC resolution of synthetic intermediates of armodafinil and related substances.

  Journal of separation science 20080401

• Chest tightness and palpitations associated with modafinil and consumption of free glutamate.

  The American journal of psychiatry 20080401

• Persistence, adherence, and switch rates among extended-release and immediate-release overactive bladder medications in a regional managed care plan.

  Journal of managed care pharmacy : JMCP 20080401

• Immobilization of selenite on Fe3O4 and Fe/Fe3C ultrasmall particles.

  Environmental science & technology 20080401

• Comparative efficacy and safety of extended-release and instant-release tolterodine in children with neural tube defects having cystometric abnormalities.

  Journal of pediatric urology 20080401

• Case 36-2007: a woman with rash, fever, and hypotension.

  The New England journal of medicine 20080327

• Systematic review: randomized, controlled trials of nonsurgical treatments for urinary incontinence in women.

  Annals of internal medicine 20080318

• Synthesis and pharmacological evaluation of bicyclic SNC80 analogues with separated benzhydryl moiety.

  Bioorganic & medicinal chemistry 20080315

• Smoked cocaine self-administration is decreased by modafinil.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080301

• Efficacy of caffeine and modafinil in counteracting sleep deprivation in the marmoset monkey.

  Psychopharmacology 20080301

• The effects of a type 4 phosphodiesterase inhibitor and the muscarinic cholinergic antagonist tolterodine tartrate on detrusor overactivity in female rats with bladder outlet obstruction.

  BJU international 20080301

• The metabotropic glutamate receptor 7 (mGluR7) allosteric agonist AMN082 modulates nucleus accumbens GABA and glutamate, but not dopamine, in rats.

  Neuropharmacology 20080301

• Cerebral blood flow changes in man by wake-promoting drug, modafinil: a randomized double blind study.

  Journal of sleep research 20080301

• Modafinil improves symptoms of attention-deficit/hyperactivity disorder across subtypes in children and adolescents.

  The Journal of pediatrics 20080301

• Re: Modafinil for treatment of fatigue in post-polio syndrome: a randomized controlled trial.

  Neurology 20080226

• Placebo and modafinil effect on sleepiness in obstructive sleep apnea.

  Progress in neuro-psychopharmacology & biological psychiatry 20080215

• Synthesis and cytotoxicity of dinuclear complexes containing ruthenium(II) bipyridyl units linked by a bis(pyridylimine) ligand.

  Dalton transactions (Cambridge, England : 2003) 20080207

• Picosecond kinetic study of the photoinduced homolysis of benzhydryl acetates: the nature of the conversion of radical pairs into ion pairs.

  Journal of the American Chemical Society 20080206

• Armodafinil improves wakefulness and long-term episodic memory in nCPAP-adherent patients with excessive sleepiness associated with obstructive sleep apnea.

  Sleep & breathing = Schlaf & Atmung 20080201

• The 5-min pupillary alertness test is sensitive to modafinil: a placebo controlled study in patients with sleep apnea.

  Psychopharmacology 20080201

• Tolterodine and imipramine in refractory enuresis; a placebo-controlled crossover study.

  Pediatric nephrology (Berlin, Germany) 20080201

• Thorough QT study with recommended and supratherapeutic doses of tolterodine.

  Clinical pharmacology and therapeutics 20080201

• Satisfaction with tolterodine: assessing symptom-specific patient-reported goal achievement in the treatment of overactive bladder in female patients (STARGATE study).

  International journal of clinical practice 20080201

• Asymmetric 1,3-dipolar cycloadditions of N-benzyl and N-diphenylmethyl nitrones and alpha,beta-unsaturated aldehydes catalyzed by bis-titanium chiral Lewis acids.

  Chemistry, an Asian journal 20080201

• Micellar electrokinetic chromatographic screening of letrozole and its metabolite in human urine: validation and robustness/ruggedness evaluation.

  Electrophoresis 20080201

• Methylphenidate and depression.

  Journal of clinical psychopharmacology 20080201

• Neural correlates of arousal-induced circadian clock resetting: hypocretin/orexin and the intergeniculate leaflet.

  The European journal of neuroscience 20080201

• Psychopharmacology news.

  Journal of child and adolescent psychopharmacology 20080201

• Ethical use of cogniceuticals in the militaries of democratic nations.

  The American journal of bioethics : AJOB 20080201

• 1-Benzhydryl-4-(4-chloro-phenyl-sulfonyl)piperazine.

  Acta crystallographica. Section E, Structure reports online 20080201

• Low dose of alertness drug counters 'family fatigue'.

  Nature 20080131

• Tolterodine does not affect memory assessed by passive-avoidance response test in mice.

  European journal of pharmacology 20080128

• CSF histamine levels in rats reflect the central histamine neurotransmission.

  Neuroscience letters 20080117

• Exploring the neuroprotective effects of modafinil in a marmoset Parkinson model with immunohistochemistry, magnetic resonance imaging and spectroscopy.

  Brain research 20080116

• Involvement of central histaminergic systems in modafinil-induced but not methylphenidate-induced increases in locomotor activity in rats.

  European journal of pharmacology 20080114

• Interactions of attention-deficit/hyperactivity disorder therapeutic agents with the efflux transporter P-glycoprotein.

  European journal of pharmacology 20080114

• Parallel analysis of stimulants in saliva and urine by gas chromatography/mass spectrometry: perspectives for 'in competition' anti-doping analysis.

  Analytica chimica acta 20080114

• Modafinil as a treatment for Attention-Deficit/Hyperactivity Disorder in children and adolescents: a double blind, randomized clinical trial.

  Progress in neuro-psychopharmacology & biological psychiatry 20080101

• The effects of anticholinergic drugs on attention span and short-term memory skills in children.

  Neurourology and urodynamics 20080101

• Modafinil and nicotine interactions in abstinent smokers.

  Human psychopharmacology 20080101

• Stress modulation of the memory retrograde-enhancing effects of the awakening drug modafinil in mice.

  Psychopharmacology 20080101

• Interaction profile of armodafinil with medications metabolized by cytochrome P450 enzymes 1A2, 3A4 and 2C19 in healthy subjects.

  Clinical pharmacokinetics 20080101

• Effects of cocaine, methamphetamine and modafinil challenge on sleep rebound after paradoxical sleep deprivation in rats.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20080101

• A population-based study to investigate host genetic factors associated with hepatitis B infection and pathogenesis in the Chinese population.

  BMC infectious diseases 20080101

• Treatment-emergent hypomania or mania with modafinil.

  The American journal of psychiatry 20080101

• Survey assessment of continuation of and satisfaction with pharmacological treatment for urinary incontinence.

  Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20080101

• Pharmacological effects of propiverine and its active metabolite, M-1, on isolated human urinary bladder smooth muscle, and on bladder contraction in rats.

  International journal of urology : official journal of the Japanese Urological Association 20080101

• A randomized trial of modafinil for the treatment of fatigue and excessive daytime sleepiness in individuals with chronic traumatic brain injury.

  The Journal of head trauma rehabilitation 20080101

• Use of dronabinol for cannabis dependence: two case reports and review.

  The American journal on addictions 20080101

• Effects of potential agonist-replacement therapies for stimulant dependence on inhibitory control in cocaine abusers.

  The American journal of drug and alcohol abuse 20080101

• A randomized controlled phase IIb trial of antigen-antibody immunogenic complex therapeutic vaccine in chronic hepatitis B patients.

  PloS one 20080101

• Approved and investigational uses of modafinil : an evidence-based review.

  Drugs 20080101

• A case of isocyanate-induced asthma possibly complicated by food allergy after peanut consumption: a case report.

  Journal of occupational medicine and toxicology (London, England) 20080101

• AMN 082, an agonist of mGluR7, exhibits mixed anti- and proconvulsant effects in developing rats.

  Physiological research 20080101

• Abstracts of papers presented at the 2008 pittsburgh conference.

  Journal of automated methods & management in chemistry 20080101

• 2-O-Benzhydryl-3,4-(S)-O-benzyl-idene-d-lyxono-1,4-lactone.

  Acta crystallographica. Section E, Structure reports online 20080101

• Effects of antimuscarinics on voiding function after cerebral infarction in a rat model of overactive bladder.

  European journal of pharmacology 20071222

• Staying awake puts pressure on brain arousal systems.

  The Journal of clinical investigation 20071203

• Prolonged wakefulness induces experience-dependent synaptic plasticity in mouse hypocretin/orexin neurons.

  The Journal of clinical investigation 20071203

• HSPA1A is an important regulator of the stability and function of ZNF198 and its oncogenic derivative, ZNF198-FGFR1.

  Journal of cellular biochemistry 20071201

• Subacute oral toxicity study of bisphenol F based on the draft protocol for the 'Enhanced OECD Test Guideline no. 407'.

  Archives of toxicology 20071201

• Non-cholinergic modulation of antisaccade performance: a modafinil-nicotine comparison.

  Psychopharmacology 20071201

• Safety and efficacy of tolterodine extended release in men with overactive bladder symptoms and presumed non-obstructive benign prostatic hyperplasia.

  World journal of urology 20071201

• Does tolterodine extended release affect the bladder electrical perception threshold? A placebo controlled, double-blind study with 4 and 8 mg in healthy volunteers.

  The Journal of urology 20071201

• Coadministration of modafinil and a selective serotonin reuptake inhibitor from the initiation of treatment of major depressive disorder with fatigue and sleepiness: a double-blind, placebo-controlled study.

  Journal of clinical psychopharmacology 20071201

• Mixed urinary incontinence: continuing to confound?

  Current opinion in obstetrics & gynecology 20071201

• Antioxidant activity of 4-methylcoumarins.

  The Journal of pharmacy and pharmacology 20071201

• Practice parameters for the treatment of narcolepsy and other hypersomnias of central origin.

  Sleep 20071201

• Treatment of narcolepsy and other hypersomnias of central origin.

  Sleep 20071201

• A novel animal model for motion sickness and its first application in rodents.

  Physiology & behavior 20071123

• Case records of the Massachusetts General Hospital. Case 36-2007. A 31-year-old woman with rash, fever, and hypotension.

  The New England journal of medicine 20071122

• Modulation of the acoustic startle response by the level of arousal: comparison of clonidine and modafinil in healthy volunteers.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20071101

• Long-term tolerability of tolterodine extended release in children 5-11 years of age: results from a 12-month, open-label study.

  European urology 20071101

• Editorial comment on: Long-term tolerability of tolterodine extended release in children 5-11 years of age: results from a 12-month, open-label study.

  European urology 20071101

• Activation of the mGlu7 receptor elicits antidepressant-like effects in mice.

  Psychopharmacology 20071101

• A review of the effects of modafinil on cognition in schizophrenia.

  Schizophrenia bulletin 20071101

• Examination of KNK437- and quercetin-mediated inhibition of heat shock-induced heat shock protein gene expression in Xenopus laevis cultured cells.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20071101

• Modafinil restores memory performance and neural activity impaired by sleep deprivation in mice.

  Pharmacology, biochemistry, and behavior 20071101

• The orexins/hypocretins and schizophrenia.

  Schizophrenia bulletin 20071101

• Efficacy of tolterodine in women with detrusor overactivity and anterior vaginal wall prolapse: is it the same?

  BJOG : an international journal of obstetrics and gynaecology 20071101

• Electrical coupling: novel mechanism for sleep-wake control.

  Sleep 20071101

• Changes and challenges: managing ADHD in a fast-paced world.

  Journal of managed care pharmacy : JMCP 20071101

• Stay awake! Understanding, diagnosing, and successfully managing narcolepsy.

  The Journal of family practice 20071101

• Comparative in vivo uroselectivity profiles of anticholinergics, tested in a novel anesthetized rabbit model.

  European journal of pharmacology 20071031

• Nucleofugality of phenyl and methyl carbonates.

  The Journal of organic chemistry 20071026

• Evaluation of the safety of modafinil for treatment of excessive sleepiness.

  Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20071015

• Treatment outcomes in the STAR study: a subanalysis of solifenacin 5 mg and tolterodine ER 4 mg.

  European urology 20071001

• Clinical efficacy, safety, and tolerability of once-daily fesoterodine in subjects with overactive bladder.

  European urology 20071001

• A randomized double-blind placebo-controlled multicentre study to explore the efficacy and safety of tamsulosin and tolterodine in women with overactive bladder syndrome.

  BJU international 20071001

• The effects of tolterodine on bladder-filling sensations and perception thresholds to intravesical electrical stimulation: method and initial results.

  BJU international 20070901

• Modafinil exerts a dose-dependent antiepileptic effect mediated by adrenergic alpha1 and histaminergic H1 receptors in mice.

  Neuropharmacology 20070901

• Psychopharmacologic treatment of attention-deficit/hyperactivity disorder and disruptive behavior disorders.

  Pediatric annals 20070901

• Pharmacologic management of overactive bladder.

  Clinical interventions in aging 20070901

• Spectroscopic and density functional theory studies of the molecular geometry and electronic structure of classical and nonclassical radical ions derived from 7-benzhydrylidenenorbornene analogues.

  The journal of physical chemistry. A 20070816

• Enantioselective synthesis of (s)- and (R)-tolterodine by asymmetric hydrogenation of a coumarin derivative obtained by a Heck reaction.

  The Journal of organic chemistry 20070803

• Comparison of diphenhydramine and modafinil on arousal and autonomic functions in healthy volunteers.

  Journal of psychopharmacology (Oxford, England) 20070801

• Number of daytime micturitions and volume voided per micturition in the evaluation of efficacy of drugs for overactive bladder: findings from randomized clinical trials.

  European urology 20070801

• Age related pathogenesis of nocturia in patients with overactive bladder.

  The Journal of urology 20070801

• Patient satisfaction with extended release tolterodine or oxybutynin in overactive bladder.

  Current medical research and opinion 20070801

• Impact of Medicare changes in pharmacy reimbursement on patient care: two case reports.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070801

• Modafinil add-on in the treatment of bipolar depression.

  The American journal of psychiatry 20070801

• A placebo-controlled evaluation of adjunctive modafinil in the treatment of bipolar depression.

  The American journal of psychiatry 20070801

• Obstructive sleep apnea, hypertension, and wakefulness-promoting agents.

  Current hypertension reports 20070801

• Cognitive dysfunction with tolterodine use.

  American journal of obstetrics and gynecology 20070801

• Modafinil in the treatment of excessive daytime sleepiness.

  Cleveland Clinic journal of medicine 20070801

• Modafinil evokes striatal [(3)H]dopamine release and alters the subjective properties of stimulants.

  European journal of pharmacology 20070730

• Modafinil-induced hippocampal activation in narcolepsy.

  Neuroscience letters 20070711

• Effects of tolterodine on afferent neurotransmission in normal and resiniferatoxin treated conscious rats.

  The Journal of urology 20070701

• Periaqueductal gray metabotropic glutamate receptor subtype 7 and 8 mediate opposite effects on amino acid release, rostral ventromedial medulla cell activities, and thermal nociception.

  Journal of neurophysiology 20070701

• The clinical efficacy of tolterodine extended-release is maintained for 24 h in patients with overactive bladder.

  BJU international 20070701

• Synthesis of diphenylmethyl analogues and their affinity for the melanocortin-4 receptor and the serotonin transporter.

  Chemical & pharmaceutical bulletin 20070701

• [Sleep and wakefulness drugs and their indications].

  Annales pharmaceutiques francaises 20070701

• Using psychostimulants for treating residual symptoms in major depression.

  Journal of psychiatry & neuroscience : JPN 20070701

• Differential effects of modafinil and methylphenidate on stop-signal reaction time task performance in the rat, and interactions with the dopamine receptor antagonist cis-flupenthixol.

  Psychopharmacology 20070601

• Therapeutic advances in narcolepsy.

  Sleep medicine 20070601

• Efficacy of combined anticholinergic treatment and behavioral modification as a first line treatment for nonneurogenic and nonanatomical voiding dysfunction in children: a randomized controlled trial.

  The Journal of urology 20070601

• Modafinil augmentation for residual symptoms of fatigue in patients with a partial response to antidepressants.

  The Annals of pharmacotherapy 20070601

• Impact of fatigue in multiple sclerosis: the Fatigue Impact Scale for Daily Use (D-FIS).

  Multiple sclerosis (Houndmills, Basingstoke, England) 20070601

• Modafinil: new indication. For a minority of patients with sleep apnoea.

  Prescrire international 20070601

• Update on drugs for overactive bladder syndrome.

  Drug and therapeutics bulletin 20070601

• Modafinil: mischaracterization.

  The Journal of clinical psychiatry 20070601

• Infrared and Raman spectral signatures of aromatic nitration in thermoplastic urethanes.

  Applied spectroscopy 20070601

• [Virological, serological and clinical characteristics of anti-HBc IgM positive chronic hepatitis B patients].

  Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 20070601

• [Nondestructive quantitative analysis of Cofrel medicines by improved partial least squares-NIR spectroscopy].

  Guang pu xue yu guang pu fen xi = Guang pu 20070601

• Modafinil for treatment of fatigue in post-polio syndrome: a randomized controlled trial.

  Neurology 20070515

• Non-target screening of extractable and non-extractable organic xenobiotics in riverine sediments of Ems and Mulde Rivers, Germany.

  Environmental pollution (Barking, Essex : 1987) 20070501

• [Augmentation strategies for therapy resistant depression - a review].

  Psychiatrische Praxis 20070501

• Biological response of new activated acrylic bone cements with antiseptic properties. Histomorphometric analysis.

  Journal of materials science. Materials in medicine 20070501

• A standardised mini pig model for in vivo investigations of anticholinergic effects on bladder function and salivation.

  Pharmacological research 20070501

• Treatment of overactive bladder: selective use of anticholinergic agents with low drug-drug interaction potential.

  Geriatrics 20070501

• A randomized, double-blind, placebo-controlled trial of modafinil for negative symptoms in schizophrenia.

  The Journal of clinical psychiatry 20070501

• Overactive bladder: recognition requires vigilance for symptoms.

  Cleveland Clinic journal of medicine 20070501

• The brain H3-receptor as a novel therapeutic target for vigilance and sleep-wake disorders.

  Biochemical pharmacology 20070415

• Brain scans, genes provide addiction clues.

  JAMA 20070404

• Efficacy and tolerability of tolterodine extended release in male and female patients with overactive bladder.

  European urology 20070401

• Indel-based targeting of essential proteins in human pathogens that have close host orthologue(s): discovery of selective inhibitors for Leishmania donovani elongation factor-1alpha.

  Proteins 20070401

• Modafinil's use in combating interferon-induced fatigue.

  Digestive diseases and sciences 20070401

• Developments in laboratory diagnostics for isocyanate asthma.

  Current opinion in allergy and clinical immunology 20070401

• [Comment on the STAR study: Comparison of the efficacy and tolerance of solifenacin and tolterodine retard in the treatment of overactive bladder].

  Der Urologe. Ausg. A 20070401

• Acute chorea and hyperthermia after concurrent use of modafinil and tranylcypromine.

  The American journal of psychiatry 20070401

• Onset of efficacy of tolterodine extended release in patients with overactive bladder.

  Current medical research and opinion 20070401

• Comparative evaluation of efficacy of use of tamsulosin and/or tolterodine for medical treatment of distal ureteral stones.

  Urology 20070401

• Modafinil: serious skin reactions.

  Prescrire international 20070401

• Behavioral and subjective effects of d-amphetamine and modafinil in healthy adults.

  Experimental and clinical psychopharmacology 20070401

• Psychostimulants and military operations.

  Military medicine 20070401

• Evaluation of anticonvulsant and analgesic effects of benzyl- and benzhydryl ureides.

  European journal of pharmacology 20070322

• Treatment of men with lower urinary tract symptoms and overactive bladder.

  JAMA 20070321

• Treatment of men with lower urinary tract symptoms and overactive bladder.

  JAMA 20070321

• Polymer-supported (2,6-dichloro- 4-alkoxyphenyl)(2,4-dichlorophenyl)methanol: a new linker for solid-phase organic synthesis.

  Organic letters 20070315

• Efficacy and safety of combined therapy with terazosin and tolteradine for patients with lower urinary tract symptoms associated with benign prostatic hyperplasia: a prospective study.

  Chinese medical journal 20070305

• Adjunct armodafinil improves wakefulness and memory in obstructive sleep apnea/hypopnea syndrome.

  Respiratory medicine 20070301

• [Urinary symptoms and urodynamic findings in Parkinson's disease].

  Neurologia (Barcelona, Spain) 20070301

• Modafinil improves attention, inhibitory control, and reaction time in healthy, middle-aged rats.

  Pharmacology, biochemistry, and behavior 20070301

• Thorough QT study with recommended and supratherapeutic doses of tolterodine.

  Clinical pharmacology and therapeutics 20070301

• Modafinil improves primary nocturnal enuresis in multiple sclerosis.

  European journal of neurology 20070301

• An enantiospecific HPLC method for the determination of (S)-enantiomer impurities in (R)-tolterodine tartarate.

  Die Pharmazie 20070301

• [Evaluation of the ELISA diagnostic kits for hepatitis E virus antibody in the reference serum, the suspect patients of hepatitis E and normal persons' sera].

  Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 20070301

• Skin exposure to isocyanates: reasons for concern.

  Environmental health perspectives 20070301

• [Narcolepsy and anesthesia].

  Revista espanola de anestesiologia y reanimacion 20070301

• Why choose modafinil for excessive daytime sleepiness?

  Issues in mental health nursing 20070301

• An open study of modafinil for the treatment of daytime somnolence and fatigue in primary biliary cirrhosis.

  Alimentary pharmacology & therapeutics 20070215

• A new class of macrocyclic receptors from iota-peptides.

  Journal of the American Chemical Society 20070214

• Modafinil inhibits rat midbrain dopaminergic neurons through D2-like receptors.

  Neuropharmacology 20070201

• Effects of (S)-3,4-DCPG, an mGlu8 receptor agonist, on inflammatory and neuropathic pain in mice.

  Neuropharmacology 20070201

• Achieving continence with antimuscarinic therapy for overactive bladder: effects of baseline incontinence severity and bladder diary duration.

  BJU international 20070201

• Comparative evaluation of central muscarinic receptor binding activity by oxybutynin, tolterodine and darifenacin used to treat overactive bladder.

  The Journal of urology 20070201

• A randomized, double-blind, crossover trial of modafinil on mood.

  Journal of clinical psychopharmacology 20070201

• Modafinil therapy for apathy in an elderly patient.

  The Annals of pharmacotherapy 20070201

• Modafinil treatment for fatigue associated with fibromyalgia.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20070201

• [Detrusitol and memory impairment].

  Lakartidningen 20070201

• Modafinil enhances extracellular levels of dopamine in the nucleus accumbens and increases wakefulness in rats.

  Behavioural brain research 20070125

• Low-resolution brain electromagnetic tomography (LORETA) identifies brain regions linked to psychometric performance under modafinil in narcolepsy.

  Psychiatry research 20070115

• Studies on dechlorination of DDT (1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane) using magnesium/palladium bimetallic system.

  Journal of hazardous materials 20070102

• mGluR7 undergoes rapid internalization in response to activation by the allosteric agonist AMN082.

  Neuropharmacology 20070101

• Design of the Behavior Enhances Drug Reduction of Incontinence (BE-DRI) study.

  Contemporary clinical trials 20070101

• The responsiveness of the OAB-q among OAB patient subgroups.

  Neurourology and urodynamics 20070101

• The Mg-oppenauer oxidation as a mild method for the synthesis of aryl and metallocenyl ketones.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

• Relationships among symptoms, bother, and treatment satisfaction in overactive bladder patients.

  Neurourology and urodynamics 20070101

• P300 and treatment effect of modafinil on fatigue in multiple sclerosis.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20070101

• Medicinal studies in palliative care: impact of the EU clinical trials directive.

  Palliative medicine 20070101

• Pharmacological characterization of a new antimuscarinic agent, solifenacin succinate, in comparison with other antimuscarinic agents.

  Biological & pharmaceutical bulletin 20070101

• Male overactive bladder: the role of urodynamics and anticholinergics.

  Current urology reports 20070101

• Does modafinil enhance activity of patients with myotonic dystrophy?: a double-blind placebo-controlled crossover study.

  Journal of neurology 20070101

• Correlations between the ICIQ-SF score and urodynamic findings.

  Neurourology and urodynamics 20070101

• Safety and tolerability of extended-release oxybutynin once daily in urinary incontinence: combined results from two phase 4 controlled clinical trials.

  International urology and nephrology 20070101

• Using patient-collected clinical samples and sera to detect and quantify the severe acute respiratory syndrome coronavirus (SARS-CoV).

  Virology journal 20070101

• Effect of adjunctive modafinil on wakefulness and quality of life in patients with excessive sleepiness-associated obstructive sleep apnoea/hypopnoea syndrome: a 12-month, open-label extension study.

  CNS drugs 20070101

• [Rest for safety: which stakes?].

  Annales francaises d'anesthesie et de reanimation 20070101

• Familial narcolepsy.

  Neurologia i neurochirurgia polska 20070101

• Long-term efficacy of tolterodine and patient compliance in pediatric patients with neurogenic detrusor overactivity.

  Urologia internationalis 20070101

• DABCO and DMAP--why are they different in organocatalysis?

  Angewandte Chemie (International ed. in English) 20070101

• Characterization of metabolites of a NK1 receptor antagonist, CJ-11,972, in human liver microsomes and recombinant human CYP isoforms by liquid chromatography/tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20070101

• Bisphenol-A and chlorinated derivatives in adipose tissue of women.

  Reproductive toxicology (Elmsford, N.Y.) 20070101

• Modafinil augmentation of selective serotonin reuptake inhibitor therapy in MDD partial responders with persistent fatigue and sleepiness.

  Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20070101

• Efficacy and impact of botulinum toxin A on quality of life in patients with neurogenic detrusor overactivity: a randomised, placebo-controlled, double-blind study.

  Scandinavian journal of urology and nephrology 20070101

• A rational combination of intravesical and systemic agents for the treatment of interstitial cystitis.

  Scandinavian journal of urology and nephrology 20070101

• Narcolepsy: treatment issues.

  The Journal of clinical psychiatry 20070101

• The heat shock protein inhibitor KNK437 induces neurite outgrowth in PC12 cells.

  Neuroscience letters 20061227

• Disposition and metabolic profiling of bisphenol F in pregnant and nonpregnant rats.

  Journal of agricultural and food chemistry 20061227

• Dechlorination of DDT, DDD and DDE in soil (slurry) phase using magnesium/palladium system.

  Journal of colloid and interface science 20061201

• Retrospective evaluation of outcomes in patients with overactive bladder receiving tolterodine versus oxybutynin.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20061201

• Impact of modafinil on prefrontal executive function in schizophrenia.

  The American journal of psychiatry 20061201

• Effects of bladder training and/or tolterodine in female patients with overactive bladder syndrome: a prospective, randomized study.

  Journal of Korean medical science 20061201

• Modafinil in children and adolescents with attention-deficit/hyperactivity disorder: a preliminary 8-week, open-label study.

  Current medical research and opinion 20061201

• Effects of KNK437 on heat-induced methylation of histone H3 in human oral squamous cell carcinoma cells.

  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20061201

• Discovering inhibitors of human sirtuin type 2: novel structural scaffolds.

  Journal of medicinal chemistry 20061130

• Nucleophilic reactivities of indoles.

  The Journal of organic chemistry 20061124

• Tolterodine and tamsulosin for treatment of men with lower urinary tract symptoms and overactive bladder: a randomized controlled trial.

  JAMA 20061115

• The puzzle of overactive bladder: controversies, inconsistencies, and insights.

  International urogynecology journal and pelvic floor dysfunction 20061101

• Comparison of pramipexole and modafinil on arousal, autonomic, and endocrine functions in healthy volunteers.

  Journal of psychopharmacology (Oxford, England) 20061101

• Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

  Journal of molecular graphics & modelling 20061101

• Modafinil occupies dopamine and norepinephrine transporters in vivo and modulates the transporters and trace amine activity in vitro.

  The Journal of pharmacology and experimental therapeutics 20061101

• Tolterodine for treatment of overactive bladder.

  The Urologic clinics of North America 20061101

• Treatment of the overactive bladder syndrome with muscarinic receptor antagonists: a matter of metabolites?

  Naunyn-Schmiedeberg's archives of pharmacology 20061101

• Re: safety and tolerability of tolterodine for the treatment of overactive bladder in men with bladder outlet obstruction.

  The Journal of urology 20061101

• Modafinil and unconstrained motor activity in schizophrenia: double-blind crossover placebo-controlled trial.

  The British journal of psychiatry : the journal of mental science 20061101

• Synthesis, characterization, properties, and drug release of poly(alkyl methacrylate-b-isobutylene-b-alkyl methacrylate).

  Biomacromolecules 20061101

• In vitro preclinical cardiac assessment of tolterodine and terodiline: multiple factors predict the clinical experience.

  Journal of cardiovascular pharmacology 20061101

• Armodafinil, the R-enantiomer of modafinil: wake-promoting effects and pharmacokinetic profile in the rat.

  Pharmacology, biochemistry, and behavior 20061101

• Effectiveness of tolterodine in nonneurogenic voiding dysfunction.

  Indian pediatrics 20061101

• Modafinil activates cortical and subcortical sites in the sleep-deprived state.

  Sleep 20061101

• Manic switch in a patient with treatment-resistant bipolar depression treated with modafinil.

  The Journal of clinical psychiatry 20061101

• Oral pretreatment with ebselen enhances heat shock protein 72 expression and reduces myocardial infarct size.

  Hypertension research : official journal of the Japanese Society of Hypertension 20061101

• [More quality of life again with tolterodine].

  Praxis 20061018

• Synthesis and biological properties of novel, uracil-containing histone deacetylase inhibitors.

  Journal of medicinal chemistry 20061005

• Absence of mood switch with and tolerance to modafinil: a replication study from a large private practice.

  Journal of affective disorders 20061001

• Use of modafinil for the treatment of attention deficit/hyperactivity disorder.

  The Annals of pharmacotherapy 20061001

• Management of methamphetamine abuse and dependence.

  Current psychiatry reports 20061001

• EFNS guidelines on management of narcolepsy.

  European journal of neurology 20061001

• Treatment of fatigue: modafinil, methylphenidate, and goals of care.

  Journal of palliative medicine 20061001

• Dog EEG for wake-promotion studies.

  Current protocols in pharmacology 20061001

• Insight on the NMR study of supramolecular gels and its application to monitor molecular recognition on self-assembled fibers.

  The Journal of organic chemistry 20060929

• Enantiomeric purity methods for three pharmaceutical compounds by electrokinetic capillary chromatography utilizing highly sulfated-gamma-cyclodextrin as the chiral selector.

  Journal of chromatography. A 20060915

• Poisonings with diphenhydramine--a survey of 68 clinical and 55 death cases.

  Forensic science international 20060912

• Inhibitor discovery targeting the intermediate structure of beta-amyloid peptide on the conformational transition pathway: implications in the aggregation mechanism of beta-amyloid peptide.

  Biochemistry 20060912

• Effectiveness and tolerability of extended-release oxybutynin vs extended-release tolterodine in women with or without prior anticholinergic treatment for overactive bladder.

  International urogynecology journal and pelvic floor dysfunction 20060901

• An unprecedented rearrangement in collision-induced mass spectrometric fragmentation of protonated benzylamines.

  Journal of mass spectrometry : JMS 20060901

• Neuroprotective effects of modafinil in a marmoset Parkinson model: behavioral and neurochemical aspects.

  Behavioural pharmacology 20060901

• Study on the reactivity of diarylmethane derivatives in supercritical alcohols media: reduction of diarylmethanols and diaryl ketones to diarylmethanes using supercritical 2-propanol.

  Chemical & pharmaceutical bulletin 20060901

• Effects of bifemelane on the calcium level and ATP release of the human origin astrocyte clonal cell.

  Journal of pharmacological sciences 20060901

• Additivity rules using similarity models for chemical reactivity: calculation and interpretation of electrofugality and nucleofugality.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20060825

• Ligands with a 3,3-diphenylpentane skeleton for nuclear vitamin D and androgen receptors: Dual activities and metabolic activation.

  Bioorganic & medicinal chemistry 20060815

• Immobilized methyltrioxo rhenium (MTO)/H2O2 systems for the oxidation of lignin and lignin model compounds.

  Bioorganic & medicinal chemistry 20060801

• Complement inhibitors selectively attenuate injury following administration of cobra venom factor to rats.

  International immunopharmacology 20060801

• Modafinil for atypical depression: effects of open-label and double-blind discontinuation treatment.

  Journal of clinical psychopharmacology 20060801

• A meta-analysis comparing trials of antimuscarinic medications funded by industry or not.

  BJU international 20060801

• Tolterodine extended release improves overactive bladder symptoms in men with overactive bladder and nocturia.

  Urology 20060801

• Patient-reported outcomes in overactive bladder: importance for determining clinical effectiveness of treatment.

  Urology 20060801

• Medical therapy for obstructive sleep apnea: a review by the Medical Therapy for Obstructive Sleep Apnea Task Force of the Standards of Practice Committee of the American Academy of Sleep Medicine.

  Sleep 20060801

• Induction of radiation resistance by a heat shock protein inhibitor, KNK437, in human glioblastoma cells.

  International journal of radiation biology 20060801

• Psychostimulants for hypersomnia (excessive daytime sleepiness) in myotonic dystrophy.

  The Cochrane database of systematic reviews 20060719

• Further structural exploration of trisubstituted asymmetric pyran derivatives (2S,4R,5R)-2-benzhydryl-5-benzylamino-tetrahydropyran-4-ol and their corresponding disubstituted (3S,6S) pyran derivatives: a proposed pharmacophore model for high-affinity interaction with the dopamine, serotonin, and norepinephrine transporters.

  Journal of medicinal chemistry 20060713

• Modafinil attenuates disruptions in cognitive performance during simulated night-shift work.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060701

• [Comment on the STAR study: Comparison of the efficacy and tolerance of solifenacin and tolterodine retard in the treatment of overactive bladder].

  Der Urologe. Ausg. A 20060701

• Sodium oxybate improves excessive daytime sleepiness in narcolepsy.

  Sleep 20060701

• Diphenylmethane skeleton as a multi-template for nuclear receptor ligands: preparation of FXR and PPAR ligands.

  Bioorganic & medicinal chemistry letters 20060615

• Structure-activity relationships of substituted N-benzyl piperidines in the GBR series: Synthesis of 4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(2-trifluoromethylbenzyl)piperidine, an allosteric modulator of the serotonin transporter.

  Bioorganic & medicinal chemistry 20060601

• Efficacy and tolerability of tolterodine extended-release in continent patients with overactive bladder and nocturia.

  BJU international 20060601

• Human Streptococcus suis outbreak, Sichuan, China.

  Emerging infectious diseases 20060601

• Does modafinil produce euphoria?

  The American journal of psychiatry 20060601

• Tolterodine.

  Nursing times 20060601

• The effects of caffeine, dextroamphetamine, and modafinil on humor appreciation during sleep deprivation.

  Sleep 20060601

• Symptom-specific efficacy of tolterodine extended release in patients with overactive bladder: the IMPACT trial.

  International journal of clinical practice 20060601

• Tolterodine extended release improves patient-reported outcomes in overactive bladder: results from the IMPACT trial.

  International journal of clinical practice 20060601

• Transdermal oxybutynin in the treatment of overactive bladder.

  Clinical interventions in aging 20060601

• Narcolepsy-cataplexy associated with precocious puberty.

  Neurology 20060523

• Analysis of biomarkers in rats and dogs exposed to polymeric methylenediphenyl diisocyanate (pMDI) and its glutathione adduct.

  Toxicology 20060515

• [A meta-analysis documenting the optimal tolerance profile of tolterodine].

  Revue medicale suisse 20060510

• Diphenylmethane-mediated transmethylation of methylbenzenes over H-zeolites.

  Journal of the American Chemical Society 20060503

• Modafinil [2-[(diphenylmethyl)sulfinyl]acetamide] and circadian rhythms in syrian hamsters: assessment of the chronobiotic potential of a novel alerting compound.

  The Journal of pharmacology and experimental therapeutics 20060501

• Behavioral effects of modafinil in marmoset monkeys.

  Psychopharmacology 20060501

• Streptococcal toxic shock syndrome caused by Streptococcus suis serotype 2.

  PLoS medicine 20060501

• A randomized, double-blind, placebo-controlled study of modafinil film-coated tablets in children and adolescents with attention-deficit/hyperactivity disorder.

  Journal of the American Academy of Child and Adolescent Psychiatry 20060501

• Efficacy and tolerability of tolterodine extended-release in men with overactive bladder and urgency urinary incontinence.

  BJU international 20060501

• Pharmacological approaches to the treatment of residual symptoms.

  Journal of psychopharmacology (Oxford, England) 20060501

• Prior sleep with zolpidem enhances the effect of caffeine or modafinil during 18 hours continuous work.

  Aviation, space, and environmental medicine 20060501

• Probable interaction between tolterodine and warfarin.

  Pharmacotherapy 20060501

• Serious adverse events and the modafinil augmentation study.

  CNS spectrums 20060501

• A comparison of once-daily and divided doses of modafinil in children with attention-deficit/hyperactivity disorder: a randomized, double-blind, and placebo-controlled study.

  The Journal of clinical psychiatry 20060501

• Effects of armodafinil in the treatment of residual excessive sleepiness associated with obstructive sleep apnea/hypopnea syndrome: a 12-week, multicenter, double-blind, randomized, placebo-controlled study in nCPAP-adherent adults.

  Clinical therapeutics 20060501

• Stimulation of serum- and glucocorticoid-regulated kinase-1 gene expression by endothelin-1.

  Biochemical pharmacology 20060414

• Kinetic studies of reactions of iron(IV)-oxo porphyrin radical cations with organic reductants.

  Journal of inorganic biochemistry 20060401

• Identification of small molecule antagonists of the human mas-related gene-X1 receptor.

  Analytical biochemistry 20060401

• The overactive bladder: review of current pharmacotherapy in adults. Part 1: pathophysiology and anticholinergic therapy.

  Expert opinion on pharmacotherapy 20060401

• Characterization of the radical-scavenging reaction of 2-O-substituted ascorbic acid derivatives, AA-2G, AA-2P, and AA-2S: a kinetic and stoichiometric study.

  Biological & pharmaceutical bulletin 20060401

• Nighttime dosing with tolterodine reduces overactive bladder-related nocturnal micturitions in patients with overactive bladder and nocturia.

  Urology 20060401

• A review of the use of modafinil for attention-deficit hyperactivity disorder.

  Expert review of neurotherapeutics 20060401

• A systematic review of modafinil: Potential clinical uses and mechanisms of action.

  The Journal of clinical psychiatry 20060401

• The efficacy and safety of armodafinil as treatment for adults with excessive sleepiness associated with narcolepsy.

  Current medical research and opinion 20060401

• Walking with modafinil and its use in diplegic cerebral palsy: retrospective review.

  Journal of child neurology 20060401

• Electron spin relaxation of copper(II) complexes in glassy solution between 10 and 120 K.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20060301

• Comparison of efficacy of oxybutynin and tolterodine for prevention of catheter related bladder discomfort: a prospective, randomized, placebo-controlled, double-blind study.

  British journal of anaesthesia 20060301

• Benign prostatic hyperplasia in primary care: what you need to know.

  The Journal of urology 20060301

• Safety and tolerability of tolterodine for the treatment of overactive bladder in men with bladder outlet obstruction.

  The Journal of urology 20060301

• Using anticholinergics to treat overactive bladder: the issue of treatment tolerability.

  The American journal of medicine 20060301

• Emerging pharmacological strategies in the fight against cocaine addiction.

  Expert opinion on emerging drugs 20060301

• The emergence of new drugs for overactive bladder.

  Expert opinion on emerging drugs 20060301

• Euphorigenic and abusive properties of modafinil.

  The American journal of psychiatry 20060301

• Bis[4-(salicylideneamino)phenyl]methane.

  Acta crystallographica. Section C, Crystal structure communications 20060301

• The preoptic hypothalamus and basal forebrain play opposing roles in the descending modulation of sleep and wakefulness in infant rats.

  The European journal of neuroscience 20060301

• [Fatigue and episodic exhaustion as a feature of multiple sclerosis].

  Revue neurologique 20060301

• [Pathophysiology and treatment of fatigue in multiple sclerosis].

  Revue neurologique 20060301

• Does modafinil safely and effectively treat shift-work sleep disorder?

  Nature clinical practice. Neurology 20060301

• Patients with overactive bladders deserve better.

  The New Zealand medical journal 20060217

• Kinetics of the solvolyses of benzhydryl derivatives: basis for the construction of a comprehensive nucleofugality scale.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20060208

• Intravesical instillation of human urine after oral administration of trospium, tolterodine and oxybutynin in a rat model of detrusor overactivity.

  BJU international 20060201

• Cognitive performance following modafinil versus placebo in sleep-deprived emergency physicians: a double-blind randomized crossover study.

  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20060201

• Letter regarding APM perspectives.

  The American journal of medicine 20060201

• A novel effect of bifemelane, a nootropic drug, on intracellular Ca2+ levels in rat cerebral astrocytes.

  Journal of pharmacological sciences 20060201

• Modafinil augmentation of SSRI therapy in patients with major depressive disorder and excessive sleepiness and fatigue: a 12-week, open-label, extension study.

  CNS spectrums 20060201

• Comparison of the effectiveness and side-effects of tolterodine and oxybutynin in children with detrusor instability.

  International journal of urology : official journal of the Japanese Urological Association 20060201

• Modafinil for drooling in cerebral palsy.

  Journal of child neurology 20060201

• Triplet diphenylcarbenes protected by trifluoromethyl and bromine groups. A triplet carbene surviving a day in solution at room temperature.

  Journal of the American Chemical Society 20060125

• Reaction of an Aza[60]fullerene radical with diphenylmethanes and fluorenes: a mechanistic approach.

  The Journal of organic chemistry 20060120

• Jet spectroscopy of arylmethyl radicals in the visible region: assignment of low-frequency vibrational modes in diphenylmethyl and chlorodiphenylmethyl radicals.

  Physical chemistry chemical physics : PCCP 20060114

• Synthesis of the benzhydryl motif via a Suzuki-Miyaura coupling of arylboronic acids and 3-chloroacrylonitriles.

  The Journal of organic chemistry 20060106

• Characterization of muscarinic receptor binding and inhibition of salivation after oral administration of tolterodine in mice.

  European journal of pharmacology 20060104

• Identification and quantitative determination of benproperine metabolites in human plasma and urine by liquid chromatography-tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060102

• Randomized controlled trial of modafinil for the treatment of fatigue in postpolio patients.

  Muscle & nerve 20060101

• Re: Chapple CR, Martinez-Garcia R, Selvaggi L, Toozs-Hobson P, Warnack W, Drogendijk T, Wright DM, Bolodeoku J. A comparison of the efficacy and tolerability of solifenacin succinate and extended release tolterodine at treating overactive bladder syndrome: results of the STAR trial. Eur Urol 2005;48:464-70.

  European urology 20060101

• Pharmacodynamic effects on alertness of single doses of armodafinil in healthy subjects during a nocturnal period of acute sleep loss.

  Current medical research and opinion 20060101

• Characteristics of novel dental composites containing 2,2-bis[4-(2-methoxy-3-methacryloyloxy propoxy) phenyl] propane as a base resin.

  Biomacromolecules 20060101

• Anticholinergic drugs for overactive bladder.

  American family physician 20060101

• Modafinil film-coated tablets in children and adolescents with attention-deficit/hyperactivity disorder: results of a randomized, double-blind, placebo-controlled, fixed-dose study followed by abrupt discontinuation.

  The Journal of clinical psychiatry 20060101

• New developments in the treatment of ADHD.

  The Journal of clinical psychiatry 20060101

• Bias in magnitude estimation following left hemisphere injury.

  Neuropsychologia 20060101

• Modafinil-induced modulation of working memory and plasma corticosterone in chronically-stressed mice.

  Pharmacology, biochemistry, and behavior 20060101

• Pharmacogenetic tools for the development of target-oriented cognitive-enhancing drugs.

  NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 20060101

• Modafinil-induced reversible hyperkinetic nondystonic movement disorder in a patient with major depressive disorder.

  The Journal of neuropsychiatry and clinical neurosciences 20060101

• Endothelin-A-receptor antagonist LU 302146 inhibits electrostimulation-induced bladder contractions in vivo.

  Neurourology and urodynamics 20060101

• Molecular genetics and treatment of narcolepsy.

  Annals of medicine 20060101

• The latest in treatments for incontinence in women.

  Nebraska nurse 20060101

• Effects of modafinil on cognitive performance and alertness during sleep deprivation.

  Current pharmaceutical design 20060101

• Neurogenic bladder treatment by doubling the recommended antimuscarinic dosage.

  Neurourology and urodynamics 20060101

• Symptoms of fatigue and sleepiness in major depressive disorder.

  The Journal of clinical psychiatry 20060101

• Efficacy of tolterodine in preventing urge incontinence immediately after prostatectomy.

  International urology and nephrology 20060101

• [Comparative evaluation of health hazards associated with industrial chemicals and their derivates forming during water chlorination].

  Vestnik Rossiiskoi akademii meditsinskikh nauk 20060101

• Introduction: new developments in the treatment of attention-deficit/hyperactivity disorder.

  The Journal of clinical psychiatry 20060101

• Benzyl ions from 1,1-(2,2'-dimethoxyphenyl)-substituted 2-methylpropanes under electron ionization.

  Rapid communications in mass spectrometry : RCM 20060101

• Cognitive performance during sustained wakefulness: A low dose of caffeine is equally effective as modafinil in alleviating the nocturnal decline.

  Chronobiology international 20060101

• Open-label study of adjunct modafinil for the treatment of patients with fatigue, sleepiness, and major depression treated with selective serotonin reuptake inhibitors.

  Advances in therapy 20060101

• Modafinil reduces fatigue in Charcot-Marie-Tooth disease type 1A: a case series.

  The American journal of hospice & palliative care 20060101

• An approach to daytime wetting in children.

  Advances in pediatrics 20060101

• Modafinil and cocaine interactions.

  The American journal of drug and alcohol abuse 20060101

• Shift work sleep disorder: burden of illness and approaches to management.

  Drugs 20060101

• Modafinil: is it ready for prime time?

  Journal of opioid management 20060101

• Modafinil for fatigue in MS: a randomized placebo-controlled double-blind study.

  Neurology 20051227

• Modafinil for fatigue in MS: a randomized placebo-controlled double-blind study.

  Neurology 20051227

• Dications of fluorenylidenes. The relationship between redox potentials and antiaromaticity for meta- and para-substituted diphenylmethylidenefluorenes.

  The Journal of organic chemistry 20051223

• Valproic acid-mediated Hsp70 induction and anti-apoptotic neuroprotection in SH-SY5Y cells.

  FEBS letters 20051219

• Analysis of atmospheric sesquiterpenes: sampling losses and mitigation of ozone interferences.

  Environmental science & technology 20051215

• Brown Norway rat asthma model of diphenylmethane 4,4'-diisocyanate.

  Inhalation toxicology 20051201

• Tolterodine extended release attenuates lower urinary tract symptoms in men with benign prostatic hyperplasia.

  The Journal of urology 20051201

• Modafinil-induced irritability and aggression? A report of 2 bipolar patients.

  Journal of clinical psychopharmacology 20051201

• Modafinil for daytime somnolence in Parkinson's disease: double blind, placebo controlled parallel trial.

  Journal of neurology, neurosurgery, and psychiatry 20051201

• Trial of modafinil for cocaine dependence.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20051201

• Identification of some benproperine metabolites in humans and investigation of their antitussive effect.

  Acta pharmacologica Sinica 20051201

• Ocular side-effects of tolterodine and oxybutynin, a single-blind prospective randomized trial.

  British journal of clinical pharmacology 20051201

• Efficacy and safety of modafinil film-coated tablets in children and adolescents with attention-deficit/hyperactivity disorder: results of a randomized, double-blind, placebo-controlled, flexible-dose study.

  Pediatrics 20051201

• 1-Benzhydryl-3-phenylurea and 1-benzhydryl-3-phenylthiourea derivatives: new templates among the CB1 cannabinoid receptor inverse agonists.

  Journal of medicinal chemistry 20051117

• Abrogation of heat shock protein 70 induction as a strategy to increase antileukemia activity of heat shock protein 90 inhibitor 17-allylamino-demethoxy geldanamycin.

  Cancer research 20051115

• Juvenile pig detrusor: effects of propiverine and three of its metabolites.

  European journal of pharmacology 20051107

• DPI-221 [4-((alpha-s)-alpha-((2s,5r)-2,5-dimethyl-4-(3-fluorobenzyl)-1-piperazinyl)benzyl)-N,N-diethylbenzamide]: a novel nonpeptide delta receptor agonist producing increased micturition interval in normal rats.

  The Journal of pharmacology and experimental therapeutics 20051101

• Effects of tolterodine on an overactive bladder depend on suppression of C-fiber bladder afferent activity in rats.

  The Journal of urology 20051101

• Bladder-health diaries: an assessment of 3-day vs 7-day entries.

  BJU international 20051101

• Solifenacin versus tolterodine--a head-to-head study: finally! But not final?

  Current urology reports 20051101

• Conditions of primary excessive daytime sleepiness.

  Neurologic clinics 20051101

• Efficacy of the combination of an alpha1-blocker with an anticholinergic agent in the treatment of lower urinary tract symptoms associated with bladder outlet obstruction.

  Expert opinion on pharmacotherapy 20051101

• Chronic treatment with modafinil may not be beneficial in patients with chronic fatigue syndrome.

  Journal of psychopharmacology (Oxford, England) 20051101

• Contemporary treatment options for overactive bladder.

  JAAPA : official journal of the American Academy of Physician Assistants 20051101

• Modafinil as an adjunctive treatment to sleep deprivation in depression.

  Journal of psychiatry & neuroscience : JPN 20051101

• Urinary symptoms and quality of life changes in Thai women with overactive bladder after tolterodine treatment.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20051101

• Synthesis and structure-activity relationship of the first nonpeptidergic inverse agonists for the human cytomegalovirus encoded chemokine receptor US28.

  Journal of medicinal chemistry 20051006

• Detection of modafinil in human urine by gas chromatography-mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20051004

• Modafinil for the treatment of fatigue in primary biliary cirrhosis.

  Annals of internal medicine 20051004

• Reinforcing effects of modafinil: influence of dose and behavioral demands following drug administration.

  Psychopharmacology 20051001

• Ligands with dual vitamin D3-agonistic and androgen-antagonistic activities.

  Bioorganic & medicinal chemistry letters 20051001

• Synthetic LXR agonists increase LDL in CETP species.

  Journal of lipid research 20051001

• Antiviral efficacy of VP14637 against respiratory syncytial virus in vitro and in cotton rats following delivery by small droplet aerosol.

  Antiviral research 20051001

• Use of tolterodine in children with neurogenic detrusor overactivity: relationship between dose and urodynamic response.

  The Journal of urology 20051001

• The efficacy of tolterodine for prevention of catheter-related bladder discomfort: a prospective, randomized, placebo-controlled, double-blind study.

  Anesthesia and analgesia 20051001

• A case of premature ventricular contractions with modafinil.

  The American journal of psychiatry 20051001

• Psychosis associated with modafinil and shift work.

  The American journal of psychiatry 20051001

• Albumin prevents mitochondrial depolarization and apoptosis elicited by endoplasmic reticulum calcium depletion of neuroblastoma cells.

  European journal of pharmacology 20050927

• High performance liquid chromatography-electrospray ionization mass spectrometric determination of tolterodine tartrate in human plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050925

• Dynamic nature of the transition state for the SN1 reaction mechanism of diphenylmethyl acetates.

  Journal of the American Chemical Society 20050921

• The C3a receptor antagonist SB 290157 has agonist activity.

  Immunology letters 20050915

• Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals.

  Journal of medicinal chemistry 20050908

• Propiverine versus tolterodine: efficacy and tolerability in patients with overactive bladder.

  European urology 20050901

• Does modafinil activate the locus coeruleus in man? Comparison of modafinil and clonidine on arousal and autonomic functions in human volunteers.

  Psychopharmacology 20050901

• A comparison of the efficacy and tolerability of solifenacin succinate and extended release tolterodine at treating overactive bladder syndrome: results of the STAR trial.

  European urology 20050901

• Tolterodine-induced hyponatraemia.

  Age and ageing 20050901

• Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation.

  Journal of sleep research 20050901

• Cognitive effects of modafinil in student volunteers may depend on IQ.

  Pharmacology, biochemistry, and behavior 20050901

• The effect of modafinil on self-esteem in spinal cord injury patients: a report of 2 cases and review of the literature.

  Archives of physical medicine and rehabilitation 20050901

• The use of stimulants to modify performance during sleep loss: a review by the sleep deprivation and Stimulant Task Force of the American Academy of Sleep Medicine.

  Sleep 20050901

• Attenuation of chronic thermotolerance by KNK437, a benzylidene lactam compound, enhances thermal radiosensitization in mild temperature hyperthermia combined with low dose-rate irradiation.

  International journal of radiation biology 20050901

• Alertness drug arouses fears about 'lifestyle' misuse.

  Nature 20050825

• Modafinil for the treatment of diminished responsiveness in a patient recovering from brain surgery.

  Brain injury 20050820

• Radical addition approach to asymmetric amine synthesis: design, implementation, and comparison of chiral N-acylhydrazones.

  The Journal of organic chemistry 20050805

• Modafinil for excessive sleepiness associated with shift-work sleep disorder.

  The New England journal of medicine 20050804

• Shift-work sleep disorder--the glass is more than half empty.

  The New England journal of medicine 20050804

• Gene regulatory potential of nonsteroidal vitamin D receptor ligands.

  Molecular endocrinology (Baltimore, Md.) 20050801

• Studies of the biogenic amine transporters. XI. Identification of a 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR12909) analog that allosterically modulates the serotonin transporter.

  The Journal of pharmacology and experimental therapeutics 20050801

• Thyroid hormone receptor-beta-selective agonist GC-24 spares skeletal muscle type I to II fiber shift.

  Cell and tissue research 20050801

• Design of antagonists for NMDA and AMPA receptors.

  Neuropharmacology 20050801

• Effect of the proton pump inhibitor omeprazole on the pharmacokinetics of extended-release formulations of oxybutynin and tolterodine.

  Journal of clinical pharmacology 20050801

• Signaling through up-regulated C3a receptor is key to the development of experimental lupus nephritis.

  Journal of immunology (Baltimore, Md. : 1950) 20050801

• Efficacy of tolterodine as a first-line treatment for non-neurogenic voiding dysfunction in children.

  BJU international 20050801

• Discovery of novel trisubstituted asymmetric derivatives of (2S,4R,5R)-2-benzhydryl-5-benzylaminotetrahydropyran-4-ol, exhibiting high affinity for serotonin and norepinephrine transporters in a stereospecific manner.

  Journal of medicinal chemistry 20050728

• Molecular structure extracted from residual dipolar couplings: diphenylmethane dissolved in a nematic liquid crystal.

  The Journal of chemical physics 20050722

• Which anticholinergic drug for overactive bladder symptoms in adults.

  The Cochrane database of systematic reviews 20050720

• Arousal mechanisms: speedy flies don't sleep at night.

  Current biology : CB 20050712

• Studies of drug binding to plasma proteins using a variant of equilibrium dialysis.

  Journal of pharmaceutical and biomedical analysis 20050701

• Comparison of symptom severity and treatment response in patients with incontinent and continent overactive bladder.

  European urology 20050701

• Modafinil modulates anterior cingulate function in chronic schizophrenia.

  The British journal of psychiatry : the journal of mental science 20050701

• Double-blind, placebo-controlled study of modafinil for fatigue and cognition in schizophrenia patients treated with psychotropic medications.

  The Journal of clinical psychiatry 20050701

• Fatigue in military aviation: an overview of US military-approved pharmacological countermeasures.

  Aviation, space, and environmental medicine 20050701

• Assessment and management of urinary incontinence.

  The Nurse practitioner 20050701

• Role of protein kinase C in the monocyte-derived macrophage-mediated biodegradation of polycarbonate-based polyurethanes.

  Journal of biomedical materials research. Part A 20050701

• Persistence with overactive bladder pharmacotherapy in a Medicaid population.

  The American journal of managed care 20050701

• Medical costs after initiation of drug treatment for overactive bladder: effects of selection bias on cost estimates.

  The American journal of managed care 20050701

• Economic impact of extended-release tolterodine versus immediate- and extended-release oxybutynin among commercially insured persons with overactive bladder.

  The American journal of managed care 20050701

• Treatment of overactive bladder: a model comparing extended-release formulations of tolterodine and oxybutynin.

  The American journal of managed care 20050701

• Safety and tolerability of tolterodine for the treatment of overactive bladder in adults.

  The American journal of managed care 20050701

• Agonist activity of the small molecule C3aR ligand SB 290157.

  Journal of immunology (Baltimore, Md. : 1950) 20050615

• Mixed incontinence.

  The Journal of urology 20050601

• Treatment of urge-predominant mixed urinary incontinence with tolterodine extended release: a randomized, placebo-controlled trial.

  The Journal of urology 20050601

• Sleep deprivation.

  Primary care 20050601

• Extended-release formulations of oxybutynin and tolterodine exhibit similar central nervous system tolerability profiles: a subanalysis of data from the OPERA trial.

  American journal of obstetrics and gynecology 20050601

• [Effect of diazepam and modafinil on acute hepatic failure in mice].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20050601

• Novel ozone-mediated cleavage of the benzhydryl protecting group from aziridinyl esters.

  Organic letters 20050526

• Rhodium-catalyzed asymmetric 1,4-addition of arylboronic acids to coumarins: asymmetric synthesis of (R)-tolterodine.

  Organic letters 20050526

• An evolved explanation for the molecular geometry and electronic structure of diphenyl-substituted cyclic trimethylenemethane in the ground state: a nearly planar conformation with a considerably localized electronic state.

  The Journal of organic chemistry 20050513

• Laser flash photolysis generation and kinetic studies of porphyrin-manganese-oxo intermediates. Rate constants for oxidations effected by porphyrin-Mn(V)-oxo species and apparent disproportionation equilibrium constants for porphyrin-Mn(IV)-oxo species.

  Journal of the American Chemical Society 20050511

• Comparison of doxazosin with or without tolterodine in men with symptomatic bladder outlet obstruction and an overactive bladder.

  BJU international 20050501

• Ocular side-effects of tolterodine and oxybutynin, a single-blind prospective randomized trial.

  British journal of clinical pharmacology 20050501

• Does modafinil have the potential to improve disrupted sleep patterns in patients with dementia?

  International journal of geriatric psychiatry 20050501

• Off-label administration of drugs to healthy military personnel. Dubious ethics of preventive measures.

  Journal of medical ethics 20050501

• Long-term safety, tolerability and efficacy of extended-release tolterodine in the treatment of overactive bladder in Japanese patients.

  International journal of urology : official journal of the Japanese Urological Association 20050501

• Trospium chloride for the treatment of overactive bladder with urge incontinence.

  Clinical therapeutics 20050501

• Design, synthesis and activity of novel derivatives of oxybutynin and tolterodine.

  Bioorganic & medicinal chemistry letters 20050415

• Highly enantioselective phase-transfer-catalyzed alkylation of protected alpha-amino acid amides toward practical asymmetric synthesis of vicinal diamines, alpha-amino ketones, and alpha-amino alcohols.

  Journal of the American Chemical Society 20050413

• Treating fatigue in patients with MS: one step forward, one step back.

  Neurology 20050412

• Modafinil for fatigue in MS: a randomized placebo-controlled double-blind study.

  Neurology 20050412

• Cosmetic neurology: the controversy over enhancing movement, mentation, and mood.

  Neurology 20050412

• Effects of solifenacin succinate (YM905) on detrusor overactivity in conscious cerebral infarcted rats.

  European journal of pharmacology 20050404

• Does modafinil enhance cognitive performance in young volunteers who are not sleep-deprived?

  Journal of clinical psychopharmacology 20050401

• Modafinil elicits sympathomedullary activation.

  Hypertension (Dallas, Tex. : 1979) 20050401

• Tolterodine for the treatment of daytime incontinence in children.

  The Journal of urology 20050401

• Tolterodine treatment for children with symptoms of urinary urge incontinence suggestive of detrusor overactivity: results from 2 randomized, placebo controlled trials.

  The Journal of urology 20050401

• A theoretical study of the different radical-scavenging activities of catechin, quercetin, and a rationally designed planar catechin.

  Bioorganic chemistry 20050401

• Modafinil in sports: ethical considerations.

  British journal of sports medicine 20050401

• Mania in a boy treated with modafinil for narcolepsy.

  The American journal of psychiatry 20050401

• Cognitive, behavioral, and physiological changes in Alzheimer disease patients as a function of incontinence medications.

  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20050401

• Modafinil, sleep deprivation, and cognitive function in military and medical settings.

  Military medicine 20050401

• Tolterodine for the treatment of overactive bladder: a review.

  Expert opinion on pharmacotherapy 20050401

• The responsiveness of the Overactive Bladder Questionnaire (OAB-q).

  Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 20050401

• Modafinil for treatment of residual excessive sleepiness in nasal continuous positive airway pressure-treated obstructive sleep apnea/hypopnea syndrome.

  Sleep 20050401

• DFT-PCM studies of solvent effects on the cross-interaction constants in benzhydryl cation and anion formation.

  The journal of physical chemistry. A 20050331

• Thermal decomposition of methylene-4,4'-di(ethylphenyl-carbamate) to methylene-4,4'-di(phenylisocyanate).

  Journal of hazardous materials 20050317

• Modafinil enhances the increase of extracellular serotonin levels induced by the antidepressant drugs fluoxetine and imipramine: a dual probe microdialysis study in awake rat.

  Synapse (New York, N.Y.) 20050315

• Synthesis and biological evaluation of new symmetrical derivatives as cytotoxic agents and apoptosis inducers.

  Bioorganic & medicinal chemistry 20050315

• Determination of modafinil in plasma and urine by reversed phase high-performance liquid-chromatography.

  Journal of pharmaceutical and biomedical analysis 20050309

• Design and DNA binding of an extended triple-stranded metallo-supramolecular cylinder.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20050304

• Kinetics of the reactions of halide anions with carbocations: quantitative energy profiles for s(n)1 reactions.

  Journal of the American Chemical Society 20050302

• Validation of the urgency perception scale.

  BJU international 20050301

• Assessment of modafinil on attentional processes in a five-choice serial reaction time test in the rat.

  Journal of psychopharmacology (Oxford, England) 20050301

• Photochemical reactions of triplet p-phenylbenzyl derivatives studied by using laser flash triplet-sensitization techniques.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20050301

• Tolterodinium (+)-(2R,3R)-hydrogen tartrate.

  Acta crystallographica. Section C, Crystal structure communications 20050301

• Treatment of patients with obstructive sleep apnea.

  American family physician 20050301

• Molecular genetic advances in sleep research and their relevance to sleep medicine.

  Sleep 20050301

• Effect of endothelin-1 receptor antagonists on histological and ultrastructural changes in the pancreas and trypsinogen activation in the early course of caerulein-induced acute pancreatitis in rats.

  World journal of gastroenterology 20050227

• Electron-transfer mechanism in radical-scavenging reactions by a vitamin E model in a protic medium.

  Organic & biomolecular chemistry 20050221

• Nucleophilic acyl substitutions of anhydrides with protic nucleophiles catalyzed by amphoteric, oxomolybdenum species.

  The Journal of organic chemistry 20050218

• PHARMAC responds on tolterodine for overactive bladder.

  The New Zealand medical journal 20050217

• In vitro and in vivo estrogenic activity of chlorinated derivatives of bisphenol A.

  Toxicology 20050214

• EEG-mapping differences between narcolepsy patients and controls and subsequent double-blind, placebo-controlled studies with modafinil.

  European archives of psychiatry and clinical neuroscience 20050201

• Electronic and vibrational spectra of diphenylmethane.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050201

• Effects on sleep of anticholinergics used for overactive bladder treatment in healthy volunteers aged > or = 50 years.

  BJU international 20050201

• Antimuscarinic agents exhibit local inhibitory effects on muscarinic receptors in bladder-afferent pathways.

  Urology 20050201

• Should we switch over to tolterodine in every child with non-neurogenic daytime urinary incontinence in whom oxybutynin failed?

  Urology 20050201

• Psychostimulants and G tolerance in rhesus monkeys: effects of oral modafinil and injected caffeine.

  Aviation, space, and environmental medicine 20050201

• Overactive bladder: evaluation and management in primary care.

  Cleveland Clinic journal of medicine 20050201

• Conformational adaptation of nuclear receptor ligand binding domains to agonists: potential for novel approaches to ligand design.

  The Journal of steroid biochemistry and molecular biology 20050201

• Rates and equilibria of the reactions of tertiary phosphanes and phosphites with benzhydrylium ions.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20050121

• [Therapy of bladder weakness].

  Deutsche medizinische Wochenschrift (1946) 20050121

• A double-blind, placebo-controlled trial of modafinil for cocaine dependence.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050101

• 'Unblinding' in randomized controlled drug trials for urinary incontinence: Implications for assessing outcomes when adverse effects are evident.

  Neurourology and urodynamics 20050101

• Modafinil more effectively induces wakefulness in orexin-null mice than in wild-type littermates.

  Neuroscience 20050101

• A multicenter, placebo-controlled study of modafinil augmentation in partial responders to selective serotonin reuptake inhibitors with persistent fatigue and sleepiness.

  The Journal of clinical psychiatry 20050101

• Fragmentation of sleep-wake cycle secondary to narcolepsy and Cheyne-Stokes respiration.

  Sleep medicine 20050101

• Adsorption of polypropylene from dilute solutions on a zeolite column packing.

  Journal of separation science 20050101

• Modafinil: new indications for wake promotion.

  Expert opinion on pharmacotherapy 20050101

• [Bromophenols from the brown alga Leathesia nana].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050101

• Modafinil to treat fatigue in amyotrophic lateral sclerosis: an open label pilot study.

  The American journal of hospice & palliative care 20050101

• Modafinil in poststroke depression.

  Psychosomatics 20050101

• What is modafinil?

  The Harvard mental health letter 20050101

• The detection of modafinil and its major metabolite in equine urine by liquid chromatography/mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20050101

• Executive dysfunction in major depressive disorder.

  Expert review of neurotherapeutics 20050101

• Dopaminergic-adrenergic interactions in the wake promoting mechanism of modafinil.

  Neuroscience 20050101

• Selective inhibition of endothelin receptor A as an anti-angiogenic and anti-proliferative strategy for human pancreatic cancer.

  Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20050101

• Management of cancer-related fatigue.

  Cancer investigation 20050101

• Modafinil influences the pharmacokinetics of intravenous cocaine in healthy cocaine-dependent volunteers.

  Clinical pharmacokinetics 20050101

• A retrospective chart review of the effects of modafinil on depression as monotherapy and as adjunctive therapy.

  Depression and anxiety 20050101

• Modafinil-associated weight loss in a clozapine-treated schizoaffective disorder patient.

  Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20050101

• Persistence and adherence of medications for chronic overactive bladder/urinary incontinence in the california medicaid program.

  Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20050101

• Comparison of dry mouth in women treated with extended-release formulations of oxybutynin or tolterodine for overactive bladder.

  International urology and nephrology 20050101

• Modafinil : a review of its use in excessive sleepiness associated with obstructive sleep apnoea/hypopnoea syndrome and shift work sleep disorder.

  CNS drugs 20050101

• Probing stereoselective inhibition of the acyl binding site of cholesterol esterase with four diastereomers of 2'-N-alpha-methylbenzylcarbamyl-1, 1'-bi-2-naphthol.

  BMC biochemistry 20050101

• Dose effects of modafinil in sustaining wakefulness in narcolepsy patients with residual evening sleepiness.

  The Journal of neuropsychiatry and clinical neurosciences 20050101

• Modafinil augmentation in depressed patients with partial response to antidepressants: a pilot study on self-reported symptoms covered by the Major Depression Inventory (MDI) and the Symptom Checklist (SCL-92).

  Nordic journal of psychiatry 20050101

• Urodynamic effects of oxybutynin and tolterodine in conscious and anesthetized rats under different cystometrographic conditions.

  BMC pharmacology 20050101

• Nonstimulant therapies for attention-deficit hyperactivity disorder (ADHD) in children and adults.

  Essential psychopharmacology 20050101

• Pharmacological management of overactive bladder : a systematic and critical review of published economic evaluations.

  PharmacoEconomics 20050101

• Innovative strategies for PBPC mobilization.

  Cytotherapy 20050101

• Modafinil as an alternative to methylphenidate as augmentation for depression treatment.

  Psychosomatics 20050101

• The validation of patient-rated global assessments of treatment benefit, satisfaction, and willingness to continue--the BSW.

  Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20050101

• Farnesyl-transferase inhibitor R115,777 enhances tamoxifen inhibition of MCF-7 cell growth through estrogen receptor dependent and independent pathways.

  Breast cancer research : BCR 20050101

• [Less disability in daily activities].

  Krankenpflege Journal 20050101

• Stereoselective alpha-fluoroamide and alpha-fluoro-gamma-lactone synthesis by an asymmetric zwitterionic aza-Claisen rearrangement.

  Beilstein journal of organic chemistry 20050101

• Nocturnal enuresis in children. A four-year experience in outpatient clinics of pediatric urology.

  Folia medica 20050101

• Enantioselective [4 + 2] cycloadditions of o-quinone methides: total synthesis of (+)-mimosifoliol and formal synthesis of (+)-tolterodine.

  The Journal of organic chemistry 20041224

• Benzhydryl as an efficient selective nitrogen protecting group for uracils.

  The Journal of organic chemistry 20041224

• The month-of-birth pattern in narcolepsy is moderated by cataplexy severity and may be independent of HLA-DQB1*0602.

  Sleep 20041215

• Interaction between a hydroxypiperidine analogue of 4-(2-benzhydryloxy-ethyl)-1-(4-fluorobenzyl)piperidine and Aspartate 68 in the human dopamine transporter.

  European journal of pharmacology 20041203

• Effects of modafinil on working memory processes in humans.

  Psychopharmacology 20041201

• Effect of modafinil on acute pain: a randomized double-blind crossover study.

  Journal of clinical pharmacology 20041201

• Comparison of the efficacy of tolterodine and oxybutynin in different urodynamic severity grades of idiopathic detrusor overactivity.

  European urology 20041201

• Does modafinil improve recovery?

  Anesthesia and analgesia 20041201

• Impact of a health education intervention in overactive bladder patients.

  The Canadian journal of urology 20041201

• Modafinil treatment for fatigue in HIV+ patients: a pilot study.

  The Journal of clinical psychiatry 20041201

• Dr. Makela replies to Dr. Berigan.

  The Journal of clinical psychiatry 20041201

• Falls in three patients due to timolol eye drops, tolterodine, and flecainide.

  The journals of gerontology. Series A, Biological sciences and medical sciences 20041201

• Retrospective review of modafinil use for cerebral palsy.

  Journal of child neurology 20041201

• [A clinical study of pelvic floor electrical stimulation in treatment of overactive bladder].

  Zhonghua fu chan ke za zhi 20041201

• Piperidine-based nocaine/modafinil hybrid ligands as highly potent monoamine transporter inhibitors: efficient drug discovery by rational lead hybridization.

  Journal of medicinal chemistry 20041118

• Impact of urodynamics in treatment of primary nocturnal enuresis persisting into adulthood.

  Urology 20041101

• Hallucinations with tolterodine.

  Psychiatric services (Washington, D.C.) 20041101

• Synthetic small-molecule complement inhibitors.

  Current opinion in investigational drugs (London, England : 2000) 20041101

• EEG-tomographic studies with LORETA on vigilance differences between narcolepsy patients and controls and subsequent double-blind, placebo-controlled studies with modafinil.

  Journal of neurology 20041101

• Influence of endothelin receptor antagonism on smooth muscle cell proliferation after chronic renal failure.

  Journal of cardiovascular pharmacology 20041101

• Endothelin-1 increases serum-glucocorticoid-regulated kinase-1 expression in smooth muscle cells.

  Journal of cardiovascular pharmacology 20041101

• Further structurally constrained analogues of cis-(6-benzhydrylpiperidin-3-yl)benzylamine with elucidation of bioactive conformation: discovery of 1,4-diazabicyclo[3.3.1]nonane derivatives and evaluation of their biological properties for the monoamine transporters.

  Journal of medicinal chemistry 20041007

• An update on the pharmacotherapy of excessive daytime sleepiness and cataplexy.

  Sleep medicine reviews 20041001

• Pharmacotherapy for excessive daytime sleepiness.

  Sleep medicine reviews 20041001

• Health-related quality of life of Japanese patients with overactive bladder treated with extended-release tolterodine or immediate-release oxybutynin: a randomized, placebo-controlled trial.

  World journal of urology 20041001

• Crystal and molecular structure of an (S)-(+)-enantiomer of modafinil, a novel wake-promoting agent.

  Chemical & pharmaceutical bulletin 20041001

• [Modafinil and fatigue in multiple sclerosis].

  Neurologia (Barcelona, Spain) 20041001

• Comparison of doxazosin with or without tolterodine in men with symptomatic bladder outlet obstruction and an overactive bladder.

  BJU international 20041001

• The effect of modafinil on counter-regulatory and cognitive responses to hypoglycaemia.

  Diabetologia 20041001

• Elevating our therapeutic expectations in overactive bladder.

  Journal of the American Academy of Nurse Practitioners 20041001

• Synthesis of alpha-MoTe2 nanorods via annealing Te-seeded amorphous MoTe2 particles.

  Inorganic chemistry 20040920

• What keeps us awake: the neuropharmacology of stimulants and wakefulness-promoting medications.

  Sleep 20040915

• A validated chiral HPLC method for the enantiomeric separation of tolterodine tartarate.

  Journal of pharmaceutical and biomedical analysis 20040903

• Modafinil augmentation of phenelzine for residual fatigue in dysthymia.

  The American journal of psychiatry 20040901

• Concomitant use of modafinil and tranylcypromine in a patient with narcolepsy: a case report.

  Sleep medicine 20040901

• An open-label study of adjunctive modafinil in patients with sedation related to serotonergic antidepressant therapy.

  The Journal of clinical psychiatry 20040901

• Modafinil's effects on simulator performance and mood in pilots during 37 h without sleep.

  Aviation, space, and environmental medicine 20040901

• [Clinical experience from treatment of seven SARS patients].

  Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 20040901

• Discrete bridging and terminal copper carbenes in copper-catalyzed cyclopropanation.

  Journal of the American Chemical Society 20040818

• Does concomitant stress incontinence alter the efficacy of tolterodine in patients with overactive bladder?

  The Journal of urology 20040801

• Anti-narcoleptic agent modafinil and its sulfone: a novel facile synthesis and potential anti-epileptic activity.

  Neurochemical research 20040801

• Psychostimulants: new concepts for palliative care from the modafinil experience?

  Journal of pain and symptom management 20040801

• Modafinil facilitates performance on a delayed nonmatching to position swim task in rats.

  Pharmacology, biochemistry, and behavior 20040801

• Altered sleep latency and arousal regulation in mice lacking norepinephrine.

  Pharmacology, biochemistry, and behavior 20040801

• Treatment of urge-predominant mixed urinary incontinence with tolterodine extended release: a randomized, placebo-controlled trial.

  Urology 20040801

• Modafinil treatment in patients with seasonal affective disorder/winter depression: an open-label pilot study.

  Journal of affective disorders 20040801

• Effects of a heat shock protein inhibitor KNK437 on heat sensitivity and heat tolerance in human squamous cell carcinoma cell lines differing in p53 status.

  International journal of radiation biology 20040801

• Modafinil in endozepine stupor. A case report.

  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20040801

• [Overactive bladder. New anticholinergic drug controls urinary urge].

  MMW Fortschritte der Medizin 20040708

• Modafinil improves cognition and attentional set shifting in patients with chronic schizophrenia.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040701

• Effects of modafinil on cognitive and meta-cognitive performance.

  Human psychopharmacology 20040701

• Managing excessive daytime sleepiness in adults.

  Drug and therapeutics bulletin 20040701

• Sleepiness versus sleeplessness: shift work and sleep disorders.

  The Journal of clinical psychiatry 20040701

• Association of -238G/A polymorphism of tumor necrosis factor-alpha gene promoter region with outcomes of hepatitis B virus infection in Chinese Han population.

  World journal of gastroenterology 20040615

• The effects of modafinil and cognitive behavior therapy on sleep continuity in patients with primary insomnia.

  Sleep 20040615

• Comparative anti-inflammatory activities of antagonists to C3a and C5a receptors in a rat model of intestinal ischaemia/reperfusion injury.

  British journal of pharmacology 20040601

• Motor excitability and motor behaviour after modafinil ingestion--a double-blind placebo-controlled cross-over trial.

  Journal of neural transmission (Vienna, Austria : 1996) 20040601

• On chronic fatigue syndrome.

  The American journal of psychiatry 20040601

• Effects of acute modafinil ingestion on exercise time to exhaustion.

  Medicine and science in sports and exercise 20040601

• Identification of diphenhydramine metabolites in human urine by capillary electrophoresis-ion trap-mass spectrometry.

  Electrophoresis 20040601

• Modafinil vs. caffeine: effects on fatigue during sleep deprivation.

  Aviation, space, and environmental medicine 20040601

• Running on dope.

  Newsweek 20040531

• In vitro and in vivo tissue selectivity profile of solifenacin succinate (YM905) for urinary bladder over salivary gland in rats.

  European journal of pharmacology 20040525

• Reaction of tetramethylpiperidine N-oxides with persistent triplet diphenylcarbenes.

  Organic & biomolecular chemistry 20040521

• Modafinil improves cognition and response inhibition in adult attention-deficit/hyperactivity disorder.

  Biological psychiatry 20040515

• 5-lipoxygenase inhibitors with histamine H(1) receptor antagonist activity.

  Bioorganic & medicinal chemistry letters 20040503

• Effect of duloxetine on tolterodine pharmacokinetics in healthy volunteers.

  British journal of clinical pharmacology 20040501

• The endothelin 1A receptor antagonist BSF 302146 is a potent inhibitor of neointimal and medial thickening in porcine saphenous vein-carotid artery interposition grafts.

  The Journal of thoracic and cardiovascular surgery 20040501

• Treatment of urinary incontinence with anticholinergics in patients taking cholinesterase inhibitors for dementia.

  Clinical pharmacology and therapeutics 20040501

• Use of the short form of King's Health Questionnaire to measure quality of life in patients with an overactive bladder.

  BJU international 20040501

• Modafinil improves alertness, vigilance, and executive function during simulated night shifts.

  Sleep 20040501

• [Tolterodine for bladder spasm caused by the indwelling catheter after prostate operation].

  Zhonghua nan ke xue = National journal of andrology 20040501

• [Management of neuropathic bladder in multiple sclerosis].

  La Clinica terapeutica 20040501

• Regioselective Baeyer-Villiger oxidation in 4-carbonyl-2-azetidinone series: a revisited route toward carbapenem precursor.

  The Journal of organic chemistry 20040430

• New indications for modafinil (Provigil).

  The Medical letter on drugs and therapeutics 20040426

• Experimental verification of the Smoluchowski theory for a bimolecular diffusion-controlled reaction in liquid phase.

  The Journal of chemical physics 20040415

• Influence of modafinil on somatosensory input processing in the human brain-stem.

  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20040401

• Wake-promoting agents with different mechanisms of action: comparison of effects of modafinil and amphetamine on food intake and cardiovascular activity.

  Appetite 20040401

• Modafinil improves recovery after general anesthesia.

  Anesthesia and analgesia 20040401

• Mobilization studies in mice deficient in either C3 or C3a receptor (C3aR) reveal a novel role for complement in retention of hematopoietic stem/progenitor cells in bone marrow.

  Blood 20040315

• More arrows in the quiver: new pathways and old problems with heavy alkaline earth metal diphenylmethanides.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20040305

• Cardiac ion channel effects of tolterodine.

  The Journal of pharmacology and experimental therapeutics 20040301

• Neuroprotective mechanism of modafinil on Parkinson disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

  Acta pharmacologica Sinica 20040301

• The cognitive-enhancing properties of modafinil are limited in non-sleep-deprived middle-aged volunteers.

  Pharmacology, biochemistry, and behavior 20040301

• Overactive bladder. Strategies for better recognition and management.

  Advance for nurse practitioners 20040301

• Adjunctive modafinil at initiation of treatment with a selective serotonin reuptake inhibitor enhances the degree and onset of therapeutic effects in patients with major depressive disorder and fatigue.

  The Journal of clinical psychiatry 20040301

• Canadian economic comparison of extended-release oxybutynin and immediate-release tolterodine in the treatment of overactive bladder.

  Clinical therapeutics 20040301

• A prospective trial of modafinil as an adjunctive treatment of major depression.

  Journal of clinical psychopharmacology 20040201

• Retrospective analysis of efficacy and tolerability of tolterodine in children with overactive bladder.

  European urology 20040201

• Randomized, double-blind placebo- and tolterodine-controlled trial of the once-daily antimuscarinic agent solifenacin in patients with symptomatic overactive bladder.

  BJU international 20040201

• Modafinil as an alternative to light therapy for winter depression.

  European psychiatry : the journal of the Association of European Psychiatrists 20040201

• Modafinil: a drug in search of a mechanism.

  Sleep 20040201

• Effect of the wake-promoting agent modafinil on sleep-promoting neurons from the ventrolateral preoptic nucleus: an in vitro pharmacologic study.

  Sleep 20040201

• Modafinil and antipsychotic-induced sedation.

  The Journal of clinical psychiatry 20040201

• Preliminary studies on the structure-activity and time-effect relations of the central stimulating effects of modafinil in mice.

  Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering 20040201

• Anti-tussive activity of benproperine enantiomers on citric-acid-induced cough in conscious guinea-pigs.

  The Journal of pharmacy and pharmacology 20040201

• [Treatment of bladder instability (non-neurogenic hyperactive bladder) in children, with tolterodine].

  Actas urologicas espanolas 20040201

• Dynamic light scattering in liquid and supercooled diphenylmethane.

  The Journal of chemical physics 20040115

• Poised to challenge need for sleep, 'wakefulness enhancer' rouses concerns.

  JAMA 20040114

• Nucleophilic displacement at benzhydryl centers: asymmetric synthesis of 1,1-diarylalkyl derivatives.

  Organic letters 20040108

• Comparison of in vitro selectivity profiles of solifenacin succinate (YM905) and current antimuscarinic drugs in bladder and salivary glands: a Ca2+ mobilization study in monkey cells.

  Life sciences 20040102

• Modafinil prevents the MPTP-induced increase in GABAA receptor binding in the internal globus pallidus of MPTP-treated common marmosets.

  Neuroscience letters 20040102

• Effect of modafinil on fatigue, mood, and health-related quality of life in patients with narcolepsy.

  Psychopharmacology 20040101

• Solifenacin appears effective and well tolerated in patients with symptomatic idiopathic detrusor overactivity in a placebo- and tolterodine-controlled phase 2 dose-finding study.

  BJU international 20040101

• Clinical efficacy of tolterodine with or without a simplified pelvic floor exercise regimen.

  Neurourology and urodynamics 20040101

• Modafinil monotherapy in poststroke depression.

  Psychosomatics 20040101

• Recovery from chronic fatigue syndrome with modafinil.

  Human psychopharmacology 20040101

• Modafinil treatment of excessive sedation associated with divalproex sodium.

  Canadian journal of psychiatry. Revue canadienne de psychiatrie 20040101

• [A study on the differences of emotion and depression between patients as doctor/nurse and others occupation with severe acute respiratory syndrome].

  Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20040101

• Severe acute respiratory syndrome, Beijing, 2003.

  Emerging infectious diseases 20040101

• Benefits of adjunct modafinil in an open-label, pilot study in patients with schizophrenia.

  Clinical neuropharmacology 20040101

• Management of fatigue in patients with multiple sclerosis.

  Drugs 20040101

• Effects of modafinil on wakefulness and executive function in patients with narcolepsy experiencing late-day sleepiness.

  Clinical neuropharmacology 20040101

• Modafinil for the treatment of pain-associated fatigue: review and case report.

  Journal of pain & palliative care pharmacotherapy 20040101

• Modafinil: preclinical, clinical, and post-marketing surveillance--a review of abuse liability issues.

  Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20040101

• 1-(2-pyrimidinyl)-piperazine, a buspirone metabolite, modulates bladder function in the anesthetized rat.

  Neurourology and urodynamics 20040101

• Benefit-risk assessment of tolterodine in the treatment of overactive bladder in adults.

  Drug safety 20040101

• Efficacy and safety of tolterodine in people with neurogenic detrusor overactivity.

  The journal of spinal cord medicine 20040101

• Trospium chloride in the management of overactive bladder.

  Drugs 20040101

• A comparison of extended-release oxybutynin and tolterodine for treatment of overactive bladder in women.

  International urogynecology journal and pelvic floor dysfunction 20040101

• Modafinil as adjunctive therapy in depressed outpatients.

  Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20040101

• Cost-effectiveness analysis of extended-release formulations of oxybutynin and tolterodine for the management of urge incontinence.

  PharmacoEconomics 20040101

• Effect of antacid on the pharmacokinetics of extended-release formulations of tolterodine and oxybutynin.

  Clinical pharmacokinetics 20040101

• Daytime sleepiness and insomnia as correlates of depression.

  The Journal of clinical psychiatry 20040101

• Pharmacologic management of daytime sleepiness.

  The Journal of clinical psychiatry 20040101

• New 4-[omega-(diarylmethylamino)alkyl]- and 4-[omega-(diarylmethoxy)alkyl]-1-arylpiperazines as selective 5-HT1A/5-HT2A receptor ligands with differentiated in vivo activity.

  Polish journal of pharmacology 20040101

• 4,4'-Methylenedianiline and its dihydrochloride salt.

  Report on carcinogens : carcinogen profiles 20040101

• Modafinil and sleepiness.

  American journal of respiratory and critical care medicine 20031215

• An examination of metal-ligand binding modes in rubidium diphenylmethanide.

  Journal of the American Chemical Society 20031210

• Changes in the number of HSF1 positive granules in the nucleus reflects heat shock semiquantitatively.

  Cancer letters 20031208

• Transient memory impairment and hallucinations associated with tolterodine use.

  The New England journal of medicine 20031204

• Overactive bladder: improving the efficacy of anticholinergics by dose escalation.

  Current urology reports 20031201

• Modafinil for remitted bipolar depression with hypersomnia.

  The Annals of pharmacotherapy 20031201

• Pressure-flow variables in patients treated with tolterodine for detrusor overactivity.

  BJU international 20031201

• Enhancement of learning processes following an acute modafinil injection in mice.

  Pharmacology, biochemistry, and behavior 20031201

• Modafinil as adjunct therapy for daytime sleepiness in obstructive sleep apnea: a 12-week, open-label study.

  Chest 20031201

• Bis(2,5-dimethoxy-4-methylphenyl)methane and bis(2,5-dimethoxy-3,4,6-trimethylphenyl)methane.

  Acta crystallographica. Section C, Crystal structure communications 20031201

• Analysis of electron transfer in substituted biphenylmethane.

  Annals of the New York Academy of Sciences 20031201

• Radical scavenging activity of black cumin (Nigella sativa L.), coriander (Coriandrum sativum L.), and niger (Guizotia abyssinica Cass.) crude seed oils and oil fractions.

  Journal of agricultural and food chemistry 20031119

• Antimigraine dotarizine blocks P/Q Ca2+ channels and exocytosis in a voltage-dependent manner in chromaffin cells.

  European journal of pharmacology 20031114

• Modafinil in the treatment of excessive daytime sleepiness in children.

  Sleep medicine 20031101

• Clinical efficacy and tolerability of extended-release tolterodine and immediate-release oxybutynin in Japanese and Korean patients with an overactive bladder: a randomized, placebo-controlled trial.

  BJU international 20031101

• Report of a case of immunosuppression with prednisone in an 8-year-old boy with an acute onset of hypocretin-deficiency narcolepsy.

  Sleep 20031101

• Glutamatergic agents for cocaine dependence.

  Annals of the New York Academy of Sciences 20031101

• Laser flash photolysis formation and direct kinetic studies of manganese(V)-oxo porphyrin intermediates.

  Journal of the American Chemical Society 20031015

• Design, synthesis, and anticancer properties of 4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone and analogues.

  Journal of medicinal chemistry 20031009

• Narcolepsy drug could be approved for wider use.

  Lancet (London, England) 20031004

• Cyclopropanation of vinylidenecyclopropanes. Synthesis of 1-(dihalomethylene)spiropentanes.

  The Journal of organic chemistry 20031003

• A non-peptide antagonist unusually selective for the human form of the bradykinin B2 receptor.

  International immunopharmacology 20031001

• Update on overactive bladder: pharmacologic approaches on the horizon.

  Current urology reports 20031001

• Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.

  Chemical research in toxicology 20031001

• The endothelin-1 receptor antagonists ameliorate histology and ultrastructural alterations in the pancreas and decrease trypsinogen activation in severe taurocholate pancreatitis in rats.

  International journal of experimental pathology 20031001

• You'll lose sleep over this pill.

  Fortune 20030929

• How nucleophilic are diazo compounds?

  Chemistry (Weinheim an der Bergstrasse, Germany) 20030905

• RE: Therapeutic efficacy of extended release oxybutynin chloride, and immediate release and long acting tolterodine tartrate in children with diurnal urinary incontinence.

  The Journal of urology 20030901

• Tolterodine is equally effective in patients with mixed incontinence and those with urge incontinence alone.

  BJU international 20030901

• The quest for a smart pill.

  Scientific American 20030901

• Reduced perception of urgency in treatment of overactive bladder with extended-release tolterodine.

  Obstetrics and gynecology 20030901

• Comparative pharmacokinetics of diphenhydramine in camels and horses after intravenous administration.

  Veterinary research communications 20030901

• Effects of modafinil on sustained attention performance and quality of life in OSA patients with residual sleepiness while being treated with nCPAP.

  Sleep medicine 20030901

• The effect of endothelin-1 receptor antagonists in acute experimental pancreatitis in the rats.

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030901

• Adjunct modafinil for the short-term treatment of fatigue and sleepiness in patients with major depressive disorder: a preliminary double-blind, placebo-controlled study.

  The Journal of clinical psychiatry 20030901

• Evidence for inverted region behavior in proton transfer to carbanions.

  Journal of the American Chemical Society 20030820

• TetraTab--cognitive enhancement gone wrong.

  The Lancet. Neurology 20030801

• Comparative efficacy and safety of transdermal oxybutynin and oral tolterodine versus placebo in previously treated patients with urge and mixed urinary incontinence.

  Urology 20030801

• Modafinil in children with attention-deficit hyperactivity disorder.

  Pediatric neurology 20030801

• [Effects of modafinil on visual and auditory reaction abilities and subjective fatigue level during 48 h sleep deprivation].

  Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering 20030801

• [Clinical analysis of pediatric SARS cases in Beijing].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20030801

• Physicochemical and chromatographic evaluation of benzhydrylamine-resin as an anion exchanger solid support.

  Journal of biochemical and biophysical methods 20030731

• Cataplexy worsened by modafinil.

  Sleep 20030615

• Initiating treatment with modafinil for control of excessive daytime sleepiness in patients switching from methylphenidate: an open-label safety study assessing three strategies.

  Psychopharmacology 20030601

• An alternative procedure for preparation of cefdinir.

  Farmaco (Societa chimica italiana : 1989) 20030601

• Combination treatment with an alpha-blocker plus an anticholinergic for bladder outlet obstruction: a prospective, randomized, controlled study.

  The Journal of urology 20030601

• Modafinil for treatment of cognitive side effects of antiepileptic drugs in a patient with seizures and stroke.

  Epilepsy & behavior : E&B 20030601

• Reduction in excess daytime sleepiness by modafinil in patients with myotonic dystrophy.

  Neuromuscular disorders : NMD 20030601

• Influence of acute selective endothelin-receptor-A blockade on renal hemodynamics in a rat model of chronic allograft rejection.

  Transplant international : official journal of the European Society for Organ Transplantation 20030601

• [Therapy of mixed urinary incontinence].

  Der Urologe. Ausg. A 20030601

• Modafinil treatment of opioid-induced sedation.

  Pain medicine (Malden, Mass.) 20030601

• Advances in medical management of overactive bladder.

  Mayo Clinic proceedings 20030601

• Prospective, randomized, double-blind study of the efficacy and tolerability of the extended-release formulations of oxybutynin and tolterodine for overactive bladder: results of the OPERA trial.

  Mayo Clinic proceedings 20030601

• Structure-nucleophilicity relationships for enamines.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20030523

• Oxybutynin transdermal (Oxytrol) for overactive bladder.

  The Medical letter on drugs and therapeutics 20030512

• The role of geometry on regioselectivity and rate of fluorination of fluorene and diphenylmethane with Selectfluor F-TEDA-BF4.

  Organic & biomolecular chemistry 20030507

• Modafinil and cocaine: a double-blind, placebo-controlled drug interaction study.

  Drug and alcohol dependence 20030501

• Tolterodine and memory: dry but forgetful.

  Archives of neurology 20030501

• Tin(II) chloride catalyzed reactions of diazodiphenylmethane with vicinal diols in an aprotic solvent. The reactions with cis- and trans-1,2-cyclohexanediols and 1,2-propanediol.

  Carbohydrate research 20030422

• 25-Hydroxylation of vitamin D3 in primary cultures of pig hepatocytes: evidence for a role of both CYP2D25 and CYP27A1.

  Biochemical and biophysical research communications 20030411

• Synthesis and pharmacology of site specific cocaine abuse treatment agents: 8-substituted isotropane (3-azabicyclo[3.2.1]octane) dopamine uptake inhibitors.

  Journal of medicinal chemistry 20030410

• Analysis of technical lignins by two- and three-dimensional NMR spectroscopy.

  Journal of agricultural and food chemistry 20030409

• [Urinary incontinence--treatment].

  Deutsche medizinische Wochenschrift (1946) 20030404

• An open-label trial of modafinil augmentation in patients with partial response to antidepressant therapy.

  Journal of clinical psychopharmacology 20030401

• Chiral analysis of d- and l-modafinil in human serum: application to human pharmacokinetic studies.

  Therapeutic drug monitoring 20030401

• Modafinil affects mood, but not cognitive function, in healthy young volunteers.

  Human psychopharmacology 20030401

• Non-stimulant treatment of attention-deficit/hyperactivity disorder.

  CNS spectrums 20030401

• Three case reports of modafinil use in treating sedation induced by antipsychotic medications.

  The Journal of clinical psychiatry 20030401

• N,N-diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine increases the permeability of primary mouse cerebral endothelial cell monolayers.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030401

• High affinity hydroxypiperidine analogues of 4-(2-benzhydryloxyethyl)-1-(4-fluorobenzyl)piperidine for the dopamine transporter: stereospecific interactions in vitro and in vivo.

  Journal of medicinal chemistry 20030327

• Modafinil increases histamine release in the anterior hypothalamus of rats.

  Neuroscience letters 20030320

• Modafinil maintains waking in the fruit fly drosophila melanogaster.

  Sleep 20030315

• Kinetic and stoichiometric assessment of the antioxidant activity of flavonoids by electron spin resonance spectroscopy.

  Journal of agricultural and food chemistry 20030312

• Distinctive effects of modafinil and d-amphetamine on the homeostatic and circadian modulation of the human waking EEG.

  Psychopharmacology 20030301

• The use of tolterodine in children after oxybutynin failure.

  BJU international 20030301

• Randomized trial of modafinil for treating subjective daytime sleepiness in patients with Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20030301

• Antioxidant action of a lipophilic nitroxyl radical, cyclohexane-1-spiro-2'-(4'-oxyimidazolidine-1'-oxyl) -5'-spiro-1'-cyclohexane, against lipid peroxidation under hypoxic conditions.

  Lipids 20030301

• Vibrational spectra and conformational isomerism of calixarene building blocks: 2-benzylphenol.

  Organic & biomolecular chemistry 20030221

• Synthesis of eosinophil infiltration inhibitors with antihistaminic activity.

  Chemical & pharmaceutical bulletin 20030201

• A new once-daily formulation of tolterodine provides superior efficacy and is well tolerated in women with overactive bladder.

  International urogynecology journal and pelvic floor dysfunction 20030201

• Indigo production by Escherichia coli carrying the phenol hydroxylase gene from Acinetobacter sp strain ST-550 in a water-organic solvent two-phase system.

  Applied microbiology and biotechnology 20030201

• Unexpected differences in the alpha-halogenation and related reactivity of sulfones with perhaloalkanes in KOH-t-BuOH.

  The Journal of organic chemistry 20030124

• Pro: modafinil has a role in management of sleep apnea.

  American journal of respiratory and critical care medicine 20030115

• Con: modafinil has no role in management of sleep apnea.

  American journal of respiratory and critical care medicine 20030115

• Should a pharmaceutical be approved for the broad indication of excessive sleepiness?

  American journal of respiratory and critical care medicine 20030115

• Cognitive enhancing effects of modafinil in healthy volunteers.

  Psychopharmacology 20030101

• Sonochemical polymerization of diphenylmethane.

  Ultrasonics sonochemistry 20030101

• Therapeutic efficacy of extended release oxybutynin chloride, and immediate release and long acting tolterodine tartrate in children with diurnal urinary incontinence.

  The Journal of urology 20030101

• Combination treatment with an ET(A)-receptor blocker and an ACE inhibitor is not superior to the respective monotherapies in attenuating chronic transplant vasculopathy in different aorta allotransplantation rat models.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030101

• Clinical pharmacokinetic profile of modafinil.

  Clinical pharmacokinetics 20030101

• By the way, doctor. What can you tell me about the new drug Provigil? I've read that it helps people stay awake without feeling jittery. For those of us who work a lot of overtime, it sounds like a dream come true.

  Harvard women's health watch 20030101

• Effects of ATP-sensitive K+ channel openers and tolterodine on involuntary bladder contractions in a pig model of partial bladder outlet obstruction.

  Neurourology and urodynamics 20030101

• Simplified bladder training augments the effectiveness of tolterodine in patients with an overactive bladder.

  BJU international 20030101

• [Modafinil: pharmacology and therapeutic perspectives].

  Revue neurologique 20030101

• N-benzhydryl-glycolamide: the first protecting group in peptide synthesis with a strong conformational bias.

  Biopolymers 20030101

• [Spasmex treatment of patients with hyperactive urinary bladder].

  Urologiia (Moscow, Russia : 1999) 20030101

• Transdermal oxybutynin: for overactive bladder.

  Drugs & aging 20030101

• Dosing regimen effects of modafinil for improving daytime wakefulness in patients with narcolepsy.

  Clinical neuropharmacology 20030101

• [Efficacy of enzyme-inducing agents in experimental tetrachloromethane poisoning].

  Eksperimental'naia i klinicheskaia farmakologiia 20030101

• Temporal pattern of hippocampal high-frequency oscillations during sleep after stimulant-evoked waking.

  Neuroscience 20030101

• Efficacy and safety of modafinil for improving daytime wakefulness in patients treated previously with psychostimulants.

  Sleep medicine 20030101

• Changes in the localization of heat shock protein 72 correlated with development of thermotolerance in human esophageal cancer cell line.

  Anticancer research 20030101

• Modafinil reduces excessive somnolence and enhances mood in patients with myotonic dystrophy.

  Neurology 20021224

• Role of brain alpha 1B-adrenoceptors in modafinil-induced behavioral activity.

  Synapse (New York, N.Y.) 20021215

• Methodologic shortcomings inherent in a post-hoc analysis.

  Current urology reports 20021201

• A ruthenium(II)-porphyrin-carbene complex with a weakly bonded methanol ligand.

  Acta crystallographica. Section C, Crystal structure communications 20021201

• Modafinil for the treatment of daytime sleepiness in Parkinson's disease: a double-blind, randomized, crossover, placebo-controlled polygraphic trial.

  Sleep 20021201

• Health-related quality of life of patients receiving extended-release tolterodine for overactive bladder.

  The American journal of managed care 20021201

• Long-term health-related quality of life of patients receiving extended-release tolterodine for overactive bladder.

  The American journal of managed care 20021201

• Human variability in polymorphic CYP2D6 metabolism: is the kinetic default uncertainty factor adequate?

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021101

• Studies on the tumor promoting mechanism of hard and soft segment models of polyetherurethane: Tyr265 phosphorylation of connexin43 is a key step in the GJIC inhibitory reaction induced by polyetherurethane.

  Journal of biomedical materials research 20021101

• Stress-induced subsensitivity to modafinil and its prevention by corticosteroids.

  Pharmacology, biochemistry, and behavior 20021101

• Different responses to drugs against overactive bladder in detrusor muscle of pig, guinea pig and mouse.

  European journal of pharmacology 20021101

• Conservative management in neurogenic bladder dysfunction.

  Current opinion in urology 20021101

• Modafinil for social phobia and amphetamine dependence.

  The American journal of psychiatry 20021101

• Effect of modafinil on core temperature during sustained wakefulness and exercise in a warm environment.

  Aviation, space, and environmental medicine 20021101

• Post-synthesis incorporation of a lipidic side chain into a peptide on solid support.

  Journal of peptide science : an official publication of the European Peptide Society 20021101

• New perspectives on the overactive bladder: pharmacokinetics and bioavailability.

  Urology 20021101

• Antioxidant action of 2,2,4,6-tetra-substituted 2,3-dihydro-5-hydroxybenzofuran against lipid peroxidation: effects of substituents and side chain.

  Free radical research 20021101

• Improvement of learning processes following chronic systemic administration of modafinil in mice.

  Pharmacology, biochemistry, and behavior 20021001

• Treatment of overactive bladder: the Antimuscarinic Clinical Effectiveness Trial.

  Current urology reports 20021001

• Pharmacologic treatment for detrusor overactivity.

  Current urology reports 20021001

• The newer antimuscarinic drugs: bladder control with less dry mouth.

  Cleveland Clinic journal of medicine 20021001

• Antioxidant ortho-benzoyloxyphenyl acetic acid ester, vaccihein A, from the fruit of rabbiteye blueberry (Vaccinium ashei).

  Chemical & pharmaceutical bulletin 20021001

• Circadian rhythm of rectal temperature during sleep deprivation with modafinil.

  Aviation, space, and environmental medicine 20021001

• Relationships between carbocation stabilities and electrophilic reactivity parameters, E: quantum mechanical studies of benzhydryl cation structures and stabilities.

  Journal of the American Chemical Society 20020918

• Acyclic nucleoside analogues as novel inhibitors of human mitochondrial thymidine kinase.

  Journal of medicinal chemistry 20020912

• A randomized controlled trial of tolterodine and oxybutynin on tolerability and clinical efficacy for treating Chinese women with an overactive bladder.

  BJU international 20020901

• Does gender or age affect the efficacy and safety of tolterodine?

  The Journal of urology 20020901

• Biotransformation of cyclizine in greyhounds. 2: N(1)-dealkylation and identification of some neutral and phenolic metabolites in canine urine by gas chromatography-mass spectrometry.

  Xenobiotica; the fate of foreign compounds in biological systems 20020901

• Efficiency of enzyme-inducing agents in rats with intrahepatic cholestasis.

  Bulletin of experimental biology and medicine 20020901

• Genotoxic activation of benzophenone and its two metabolites by human cytochrome P450s in SOS/umu assay.

  Mutation research 20020826

• Discriminative-stimulus effects of modafinil in cocaine-trained humans.

  Drug and alcohol dependence 20020801

• Chronic elevated endothelin-1 concentrations regulate mitogen-activated protein kinases ERK 1 and ERK 2 in vascular smooth muscle cells.

  Clinical science (London, England : 1979) 20020801

• Influence of endothelin receptor antagonists on myocardial protein kinase C isoforms in uraemic cardiomyopathy.

  Clinical science (London, England : 1979) 20020801

• Modafinil in treatment of fatigue in multiple sclerosis. Results of an open-label study.

  Journal of neurology 20020801

• Drugs under investigation for attention-deficit hyperactivity disorder.

  Current opinion in investigational drugs (London, England : 2000) 20020801

• Effects of modafinil on heat thermoregulatory responses in humans at rest.

  Canadian journal of physiology and pharmacology 20020801

• Dynamics of proton transfer at nonactivated carbons from laser flash electron photoinjection experiments.

  Journal of the American Chemical Society 20020731

• Polymer-supported ferrocenyl oxazolines for the catalyzed highly enantioselective phenyl transfer to aldehydes.

  Bioorganic & medicinal chemistry letters 20020722

• Comparison between experimental and theoretical scales of electrophilicity in benzhydryl cations.

  The Journal of organic chemistry 20020712

• Chemistry of dicationic electrophiles: superacid-catalyzed reactions of amino acetals.

  The Journal of organic chemistry 20020712

• Current pharmacotherapeutic strategies for overactive bladder.

  Expert opinion on pharmacotherapy 20020701

• Modafinil-associated clozapine toxicity.

  The American journal of psychiatry 20020701

• Psychopharmacology of wakefulness: pathways and neurotransmitters.

  The Journal of clinical psychiatry 20020701

• Comparison of the effects of modafinil and sleep deprivation on sleep and cortical EEG spectra in mice.

  Neuropharmacology 20020701

• The central nucleus of the amygdala and the wake-promoting effects of modafinil.

  Brain research 20020621

• Secondary narcolepsy in children with brain tumors.

  Sleep 20020615

• Femtosecond excitation energy transport in triarylamine dendrimers.

  Journal of the American Chemical Society 20020612

• Solvent reorganization controls the rate of proton transfer from neat alcohol solvents to singlet diphenylcarbene.

  Journal of the American Chemical Society 20020605

• Study of the addictive potential of modafinil in naive and cocaine-experienced rats.

  Psychopharmacology 20020601

• Long-term safety, tolerability and efficacy of extended-release tolterodine in the treatment of overactive bladder.

  European urology 20020601

• Spectroelectrochemistry study on the electrochemical reduction of ethidium bromide.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20020601

• Risk of delirium with concomitant use of tolterodine and acetylcholinesterase inhibitors.

  Journal of the American Geriatrics Society 20020601

• The overactive bladder: a nursing perspective.

  The American journal of nursing 20020601

• Nonpeptide bradykinin B2 receptor antagonists: conversion of rodent-selective bradyzide analogues into potent, orally-active human bradykinin B2 receptor antagonists.

  Journal of medicinal chemistry 20020523

• Assessment and conservative management of the neuropathic bladder.

  Seminars in pediatric surgery 20020501

• Tolterodine-associated acute mixed liver injury.

  The Annals of pharmacotherapy 20020501

• Efficacy, safety, and tolerability of extended-release once-daily tolterodine treatment for overactive bladder in older versus younger patients.

  Journal of the American Geriatrics Society 20020501

• Modafinil monotherapy in depression.

  European psychiatry : the journal of the Association of European Psychiatrists 20020501

• Tolterodine: as effective but better tolerated than oxybutynin in Asian patients with symptoms of overactive bladder.

  International journal of urology : official journal of the Japanese Urological Association 20020501

• Tolterodine and its active 5-hydroxymethyl metabolite: pure muscarinic receptor antagonists.

  Pharmacology & toxicology 20020501

• Achieving bladder control. Treatment in the primary care setting.

  Advance for nurse practitioners 20020501

• Oxygen transfer from sulfoxides: oxidation of alkylarenes catalyzed by a polyoxomolybdate, [PMo12O40]3-.

  Journal of the American Chemical Society 20020424

• Synthesis, biological evaluation, and binding mode of novel 1-[2-(diarylmethoxy)ethyl]-2-methyl-5-nitroimidazoles targeted at the HIV-1 reverse transcriptase.

  Journal of medicinal chemistry 20020411

• Oxygen transfer reactions. 4. Reaction of high valent oxoruthenium compounds with sulfides.

  Inorganic chemistry 20020408

• Differential enhancement of dialysate serotonin levels in distinct brain regions of the awake rat by modafinil: possible relevance for wakefulness and depression.

  Journal of neuroscience research 20020401

• Steady-state pharmacokinetics and tolerability of modafinil administered alone or in combination with dextroamphetamine in healthy volunteers.

  Journal of clinical pharmacology 20020401

• Tolterodine: a safe and effective treatment for older patients with overactive bladder.

  Journal of the American Geriatrics Society 20020401

• Dimerization of organic free radicals in solution. 1. Temperature dependent measurements.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20020401

• A multicenter, prospective, open-label study of tolterodine extended-release 4 mg for overactive bladder: the speed of onset of therapeutic assessment trial (STAT).

  Clinical therapeutics 20020401

• Flexible crosslinked benzhydryl support for gel-phase peptide synthesis.

  Protein and peptide letters 20020401

• Trace level determination of organochlorine, organophosphorus and pyrethroid pesticides in lanolin using gel permeation chromatography followed by dual gas chromatography and gas chromatography-negative chemical ionization mass spectrometric confirmation.

  Journal of chromatography. A 20020315

• Development of long-acting dopamine transporter ligands as potential cocaine-abuse therapeutic agents: chiral hydroxyl-containing derivatives of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine.

  Journal of medicinal chemistry 20020314

• Muscarinic receptor antagonist-induced lenticular opacity in rats.

  Toxicological sciences : an official journal of the Society of Toxicology 20020301

• Pharmacotherapy of the overactive bladder and advances in drug delivery.

  Clinical obstetrics and gynecology 20020301

• Is psychosis exacerbated by modafinil?

  Archives of general psychiatry 20020301

• Isolation of an Acinetobacter sp. ST-550 which produces a high level of indigo in a water-organic solvent two-phase system containing high levels of indole.

  Applied microbiology and biotechnology 20020301

• [Liver monooxygenase system inducers in the treatment of respiratory distress syndrome in newborn].

  Klinicheskaia laboratornaia diagnostika 20020301

• Acute behavioral and physiological effects of modafinil in drug abusers.

  Behavioural pharmacology 20020301

• Occurrence of phthalates and bisphenol A and F in the environment.

  Water research 20020301

• Use of modafinil in spastic cerebral palsy.

  Journal of child neurology 20020301

• Determination of modafinil, modafinil acid and modafinil sulfone in human plasma utilizing liquid-liquid extraction and high-performance liquid chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020215

• Modafinil for fatigue in multiple sclerosis.

  Journal of neurology, neurosurgery, and psychiatry 20020201

• Efficacy and safety of modafinil (Provigil) for the treatment of fatigue in multiple sclerosis: a two centre phase 2 study.

  Journal of neurology, neurosurgery, and psychiatry 20020201

• On the prodrug potential of novel aldose reductase inhibitors with diphenylmethyleneaminooxycarboxylic acid structure.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20020201

• Effect of modafinil at steady state on the single-dose pharmacokinetic profile of warfarin in healthy volunteers.

  Journal of clinical pharmacology 20020201

• Medication update.

  Southern medical journal 20020201

• Reduction of daytime sleepiness in a depressive patient during adjunct treatment with modafinil.

  Journal of psychiatric research 20020101

• Effect of modafinil on the pharmacokinetics of ethinyl estradiol and triazolam in healthy volunteers.

  Clinical pharmacology and therapeutics 20020101

• Maintaining alertness and performance during sleep deprivation: modafinil versus caffeine.

  Psychopharmacology 20020101

• [The drop in toxicity and the rise in the effectiveness of antineoplastic chemotherapy by correcting the activity of liver monooxygenases: from the experiment to the clinical practice].

  Vestnik Rossiiskoi akademii meditsinskikh nauk 20020101

• Treatment can lead to a long dry spell.

  Business and health 20020101

• Treatment of excessive daytime sleepiness in patients with Parkinson's disease with modafinil.

  Clinical neuropharmacology 20020101

• Sexual dimorphism of the catechol-O-methyltransferase gene in narcolepsy is associated with response to modafinil.

  The pharmacogenomics journal 20020101

• Once-daily, extended-release formulations of antimuscarinic agents in the treatment of overactive bladder: a review.

  European urology 20020101

• Tolterodine: selectivity for the urinary bladder over the eye (as measured by visual accommodation) in healthy volunteers.

  Drugs in R&D 20020101

• New treatment options for overactive bladder and incontinence.

  Director (Cincinnati, Ohio) 20020101

• Modafinil in the treatment of depression with severe comorbid medical illness.

  Psychosomatics 20020101

• Treatment of overactive bladder with once-daily extended-release tolterodine or oxybutynin: the antimuscarinic clinical effectiveness trial (ACET).

  Current medical research and opinion 20020101

• Clinical applications of modafinil in stimulant abusers: low abuse potential.

  The American journal on addictions 20020101

• Solid phase synthesis of PNA oligomers.

  Methods in molecular biology (Clifton, N.J.) 20020101

• Different h2 receptor antihistamines dissimilarly retard the growth of xenografted human melanoma cells in immunodeficient mice.

  Cell biology international 20020101

• Effect of tolterodine on the anticoagulant actions and pharmacokinetics of single-dose warfarin in healthy volunteers.

  Arzneimittel-Forschung 20020101

• Modafinil augmentation of mirtazapine in a failure-to-thrive geriatric inpatient.

  International journal of psychiatry in medicine 20020101

• Sleepless in America.

  Time 20011217

• A novel, tunable manganese coordination system based on a flexible 'spacer' unit: noncovalent templation effects.

  Journal of the American Chemical Society 20011205

• Is tolterodine (Detrol) or oxybutynin (Ditropan) the best for treatment of urge urinary incontinence?

  The Journal of family practice 20011201

• Cost-Effectiveness of tolterodine for patients with urge incontinence who discontinue initial therapy with oxybutynin: a Canadian perspective.

  Clinical therapeutics 20011201

• Palladium-catalyzed asymmetric diene cyclization/hydrosilylation employing functionalized silanes and disiloxanes.

  The Journal of organic chemistry 20011116

• Variations in extracellular monoamines in the prefrontal cortex and medial hypothalamus after modafinil administration: a microdialysis study in rats.

  Neuroreport 20011116

• The importance of residues in substrate recognition site 3 for the catalytic function of CYP2D25 (vitamin D 25-hydroxylase).

  Biochemical and biophysical research communications 20011109

• Application of different RP-HPLC methods for the determination of the octanol/water partition coefficient of selected tetrachlorobenzyltoluenes.

  Chemosphere 20011101

• Medical treatment of overactive bladder.

  Mayo Clinic proceedings 20011101

• Tolterodine once-daily in treatment of the overactive bladder.

  Urology 20011101

• Modafinil as adjunct therapy for daytime sleepiness in obstructive sleep apnea.

  American journal of respiratory and critical care medicine 20011101

• Tolterodine: an overview.

  World journal of urology 20011101

• The effect of tolterodine on the pharmacokinetics and pharmacodynamics of a combination oral contraceptive containing ethinyl estradiol and levonorgestrel.

  Clinical therapeutics 20011101

• Reference scales for the characterization of cationic electrophiles and neutral nucleophiles.

  Journal of the American Chemical Society 20011003

• POEMS (patient-oriented evidence that matters) spark discussion.

  The Journal of family practice 20011001

• Tolterodine: a clinical review.

  Journal of women's health & gender-based medicine 20011001

• Engineering the CYP101 system for in vivo oxidation of unnatural substrates.

  Protein engineering 20011001

• Evidence for the efficacy and safety of tolterodine in the treatment of overactive bladder.

  Expert opinion on pharmacotherapy 20011001

• Synthesis of diphenylmethane from formalin and benzene in a biphasic system with 12-tungstophosphoric acid.

  Chemical communications (Cambridge, England) 20010907

• Rational design and synthesis of novel 2,5-disubstituted cis- and trans-piperidine derivatives exhibiting differential activity for the dopamine transporter.

  Bioorganic & medicinal chemistry letters 20010903

• Physiologically based pharmacokinetic model for tetrachlorobenzyltoluenes in rat: comparison of in vitro and in vivo metabolic rates.

  Toxicological sciences : an official journal of the Society of Toxicology 20010901

• Tolterodine reduces the number of urge incontinence episodes in patients with an overactive bladder.

  European journal of obstetrics, gynecology, and reproductive biology 20010901

• Resonance Rayleigh scattering study of the interaction of heparin with some basic diphenyl naphthylmethane dyes.

  Analytical chemistry 20010815

• An enantioselective assay for (+/-)-modafinil.

  Journal of pharmaceutical and biomedical analysis 20010801

• Off-label uses of modafinil.

  The American journal of psychiatry 20010801

• Steady-state pharmacokinetics and tolerability of modafinil given alone or in combination with methylphenidate in healthy volunteers.

  Journal of clinical pharmacology 20010801

• Costs and resources associated with the treatment of overactive bladder using retrospective medical care claims data.

  Managed care interface 20010801

• Improvement of the synthesis of diphenylmethyl 7beta-(o-hydroxy)benzylideneamino-3-hydroxymethyl-3-cephem-4-carboxylate.

  Farmaco (Societa chimica italiana : 1989) 20010801

• SbF(5)-mediated reactions of oxafluorodiazirines.

  Organic letters 20010726

• Modafinil and pramipexole-associated somnolence.

  Movement disorders : official journal of the Movement Disorder Society 20010701

• Tolterodine versus oxybutynin in the treatment of urge urinary incontinence: a meta-analysis.

  American journal of obstetrics and gynecology 20010701

• Is extended-release oxybutynin (Ditropan XL) or tolterodine (Detrol) more effective in the treatment of an overactive bladder?

  The Journal of family practice 20010701

• Successful treatment of excessive daytime sleepiness in Parkinson's disease with modafinil.

  Journal of neurology 20010701

• Oxygen-carbon bond dissociation enthalpies of benzyl phenyl ethers and anisoles. An example of temperature dependent substituent effects.

  Journal of the American Chemical Society 20010613

• Clarification--Drug risk in patients with glaucoma.

  The Medical letter on drugs and therapeutics 20010611

• Modafinil for narcolepsy.

  The American journal of psychiatry 20010601

• Effects of tolterodine, trospium chloride, and oxybutynin on the central nervous system.

  Journal of clinical pharmacology 20010601

• Tolterodine: a safe and effective treatment for older patients with overactive bladder.

  Journal of the American Geriatrics Society 20010601

• Urinary incontinence management: new questions from old assumptions.

  Journal of the American Geriatrics Society 20010601

• Nucleophilic reactivities of tributylstannyl-substituted furans and thiophenes.

  Organic letters 20010531

• Identification of a selective nonpeptide antagonist of the anaphylatoxin C3a receptor that demonstrates antiinflammatory activity in animal models.

  Journal of immunology (Baltimore, Md. : 1950) 20010515

• The almost bottleable triplet carbene: 2,6-dibromo-4-tert-butyl-2',6'-bis(trifluoromethyl)-4'-isopropyldiphenylcarbene.

  Journal of the American Chemical Society 20010509

• [An example of interactions between SSRI preparations and tolterodine?].

  Lakartidningen 20010502

• Tolterodine: superior tolerability than and comparable efficacy to oxybutynin in individuals 50 years old or older with overactive bladder: a randomized controlled trial.

  The Journal of urology 20010501

• A comparison of the effects on saliva output of oxybutynin chloride and tolterodine tartrate.

  Clinical therapeutics 20010501

• Fatigue in multiple sclerosis.

  Current neurology and neuroscience reports 20010501

• Clinical experiences with tolterodine.

  Life sciences 20010427

• Detrol LA and Diropan XL for overactive bladder.

  The Medical letter on drugs and therapeutics 20010402

• Functional characterization of rat submaxillary gland muscarinic receptors using microphysiometry.

  British journal of pharmacology 20010401

• The overactive bladder in children: a potential future indication for tolterodine.

  BJU international 20010401

• Prospective randomized controlled trial of extended-release oxybutynin chloride and tolterodine tartrate in the treatment of overactive bladder: results of the OBJECT Study.

  Mayo Clinic proceedings 20010401

• Treatment of overactive bladder: long-term tolerability and efficacy of tolterodine.

  World journal of urology 20010401

• Modafinil for excessive daytime sleepiness in myotonic dystrophy.

  Neurology 20010327

• Evidence for intermolecular interaction between sulfonium and sulfide sulfur atoms and its application to synthesis of cyclic bis(disulfide) dimer.

  The Journal of organic chemistry 20010323

• Modafinil does not affect serotonin efflux from rat frontal cortex synaptosomes: comparison with known serotonergic drugs.

  Brain research 20010316

• Structure-activity relationship studies of 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives and their N-analogues: evaluation of O-and N-analogues and their binding to monoamine transporters.

  Journal of medicinal chemistry 20010315

• Use of tolterodine in children with dysfunctional voiding: an initial report.

  The Journal of urology 20010301

• Dopaminergic role in stimulant-induced wakefulness.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010301

• Tolterodine once-daily: superior efficacy and tolerability in the treatment of the overactive bladder.

  Urology 20010301

• Overactive bladder: optimizing quality of care.

  The American journal of managed care 20010301

• Food increases the bioavailability of tolterodine but not effective exposure.

  Journal of clinical pharmacology 20010301

• Randomized, double-blind, placebo-controlled crossover trial of modafinil in the treatment of residual excessive daytime sleepiness in the sleep apnea/hypopnea syndrome.

  American journal of respiratory and critical care medicine 20010301

• [Analysis of essential oil from Artemisia annul L. by extraction of different methods].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20010301

• Studies of 9-fluorenyl carbocations. intramolecular hydride migration in a substituted 9-fluorenyl carbocation.

  The Journal of organic chemistry 20010223

• First evidence of a delay-dependent working memory-enhancing effect of modafinil in mice.

  Neuroreport 20010212

• Synthesis and preliminary characterization of a high-affinity novel radioligand for the dopamine transporter.

  Synapse (New York, N.Y.) 20010201

• Effects of modafinil in children with attention-deficit/hyperactivity disorder: an open-label study.

  Journal of the American Academy of Child and Adolescent Psychiatry 20010201

• Tissue distribution of tolterodine, a muscarinic receptor antagonist, and transfer into fetus and milk in mice.

  Arzneimittel-Forschung 20010201

• Pharmacokinetics of tolterodine, a muscarinic receptor antagonist, in mouse, rat and dog. Interspecies relationship comparing with human pharmacokinetics.

  Arzneimittel-Forschung 20010201

• Methylphenidate and narcolepsy: new indication. When modafinil fails.

  Prescrire international 20010201

• Mechanisms of blockade by the novel migraine prophylactic agent, dotarizine, of various brain and peripheral vessel contractility.

  European journal of pharmacology 20010112

• The effects of KNK437, a novel inhibitor of heat shock protein synthesis, on the acquisition of thermotolerance in a murine transplantable tumor in vivo.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20010101

• Food does not influence the pharmacokinetics of a new extended release formulation of tolterodine for once daily treatment of patients with overactive bladder.

  Clinical pharmacokinetics 20010101

• Multiple dose pharmacokinetics of a new once daily extended release tolterodine formulation versus immediate release tolterodine.

  Clinical pharmacokinetics 20010101

• Tolterodine: a review of its use in the treatment of overactive bladder.

  Drugs & aging 20010101

• Galvinoxyl method for standardizing electron and proton donation activity.

  Methods in enzymology 20010101

• Antioxidant effect of capsaicin on lipid peroxidation in homogeneous solution, micelle dispersions and liposomal membranes.

  Redox report : communications in free radical research 20010101

• Twelve-month treatment of overactive bladder: efficacy and tolerability of tolterodine.

  Drugs & aging 20010101

• Failure of tolterodine to treat clozapine-induced nocturnal enuresis.

  The Annals of pharmacotherapy 20010101

• Safety profile of tolterodine as used in general practice in England: results of prescription-event monitoring.

  Drug safety 20010101

• Antioxidant activity of 5-alkoxymethyl-6-chromanols.

  Redox report : communications in free radical research 20010101

• [Effect of phencarol on pancreatic digestive enzymes in food anaphylaxis].

  Eksperimental'naia i klinicheskaia farmakologiia 20010101

• Modafinil: a gift to portmanteau.

  The American journal of hospice & palliative care 20010101

• Modafinil in fibromyalgia treatment.

  The Journal of neuropsychiatry and clinical neurosciences 20010101

• Toxicology of environmental estrogens.

  Reproduction, fertility, and development 20010101

• [Reducing of hepatotoxicity of antineoplastic chemotherapy and concomitant viral infection through control of liver metabolism: from experiment to clinical practice].

  Voprosy onkologii 20010101