1010-60-2 | 2-Chloro-1,4-naphthoquinone

Packsize	Purity	Availability	Price	Discounted Price
5g	97%	in stock	$6.00	$4.00
10g	97%	in stock	$7.00	$5.00
25g	97%	in stock	$9.00	$6.00
100g	97%	in stock	$20.00	$14.00

Description

• Catalog Number: AA04275
• Chemical Name: 2-Chloro-1,4-naphthoquinone
• CAS Number: 1010-60-2
• Molecular Formula: C10H5ClO2
• Molecular Weight: 192.5985
• MDL Number: MFCD00029187
• SMILES: O=C1C=C(Cl)C(=O)c2c1cccc2
• NSC Number: 400597

Computed Properties

• Complexity: 293
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 2
• XLogP3: 2.3

Upstream Synthesis Route

2-Chloronaphthalene-1,4-dione is a versatile compound that finds wide application in chemical synthesis due to its unique properties. As a key intermediate in the production of various organic compounds, this chemical plays a crucial role in the synthesis of pharmaceuticals, agrochemicals, and dyes. Its reactivity and structural features make it an essential building block for creating complex molecules with specific functionalities. In particular, 2-Chloronaphthalene-1,4-dione is valued for its ability to undergo diverse chemical reactions, including nucleophilic addition, substitution, and oxidation reactions, enabling the creation of a broad range of derivatives with tailored properties. Researchers and chemists rely on this compound to efficiently construct intricate molecular structures and facilitate the development of novel materials and bioactive compounds.

Literature

• On the search for potential anti-Trypanosoma cruzi drugs: synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by click chemistry reactions.

  European journal of medicinal chemistry 20120601

• Synthesis and biological evaluation of naphthoquinone analogs as a novel class of proteasome inhibitors.

  Bioorganic & medicinal chemistry 20100801

• 2-Ferrocenyl-N-(2-ferrocenylbenzo-yl)-N-(4-methyl-2-pyrid-yl)benzamide.

  Acta crystallographica. Section E, Structure reports online 20090301

• 2-Fluoro-N-(2-fluoro-benzo-yl)-N-(2-pyrid-yl)benzamide.

  Acta crystallographica. Section E, Structure reports online 20090301

• N-(3-Bromo-1,4-dioxo-1,4-dihydro-2-naphth-yl)-2-chloro-N-(2-chloro-benzoyl)benzamide.

  Acta crystallographica. Section E, Structure reports online 20090101

• 2-Chloro-3-(4-chloro-benzamido)-1,4-naphthoquinone.

  Acta crystallographica. Section E, Structure reports online 20090101

• Effect of methoxyl group position on the regioselectivity of ammonia substitution reactions involving 3,3'-dichloro-2,2'-binaphthoquinones.

  The Journal of organic chemistry 20040723