1011-92-3 | Alpha-cyanocinnamic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$16.00	$12.00
5g	98%	in stock	$42.00	$30.00
25g	98%	in stock	$139.00	$97.00
100g	98%	in stock	$449.00	$315.00

Description

• Catalog Number: AA04672
• Chemical Name: Alpha-cyanocinnamic acid
• CAS Number: 1011-92-3
• Molecular Formula: C10H7NO2
• Molecular Weight: 173.1681
• MDL Number: MFCD00016813
• SMILES: N#CC(=Cc1ccccc1)C(=O)O

Computed Properties

• Complexity: 266
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• Undefined Bond Stereocenter Count: 1
• XLogP3: 2.2

Upstream Synthesis Route

2-Cyano-3-phenylacrylic acid, also known as α-cyano cinnamic acid, is a versatile compound widely used in chemical synthesis. This compound is particularly valued for its key role as a building block in the production of various pharmaceuticals, agrochemicals, and organic compounds. Its unique chemical structure and properties make it a valuable intermediate in the synthesis of diverse compounds.2-Cyano-3-phenylacrylic acid is commonly employed in the synthesis of heterocyclic compounds and derivatives due to its ability to participate in various organic reactions, such as nucleophilic addition, condensation, and cyclization reactions. Its cyano group provides a site for further functionalization and modification, allowing for the creation of complex molecules with specific properties and functionalities.In pharmaceutical chemistry, this compound is utilized in the development of bioactive molecules and drug candidates. Its presence in the molecular structure can impart desired biological activities and pharmacological properties. Additionally, 2-Cyano-3-phenylacrylic acid serves as a valuable precursor for the synthesis of herbicides, pesticides, and other agrochemicals, contributing to advancements in crop protection and agricultural practices.Overall, the versatile nature of 2-Cyano-3-phenylacrylic acid makes it an indispensable tool in modern chemical synthesis, enabling the creation of novel molecules with diverse applications across industries.

Literature

• Mitochondrial involvement to methylglyoxal detoxification: D-Lactate/Malate antiporter in Saccharomyces cerevisiae.

  Antonie van Leeuwenhoek 20120601

• Basigin interacts with both MCT1 and MCT2 in murine spermatozoa.

  Journal of cellular physiology 20120501

• (E)-Ethyl 2-cyano-3-(2,4-dimeth-oxy-phen-yl)prop-2-enoate.

  Acta crystallographica. Section E, Structure reports online 20111101

• Theoretical investigation of novel carbazole-fluorene based D-π-A conjugated organic dyes as dye-sensitizer in dye-sensitized solar cells (DSCs).

  Journal of computational chemistry 20110601

• Inhibition of tumor lactate oxidation: consequences for the tumor microenvironment.

  Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20110601

• Alternative CHCA-based matrices for the analysis of low molecular weight compounds by UV-MALDI-tandem mass spectrometry.

  Journal of mass spectrometry : JMS 20110201

• Evaluation of Fructooligosaccharides and Inulins as Potentially Health Benefiting Food Ingredients by HPAEC-PED and MALDI-TOF MS.

  International journal of analytical chemistry 20090101

• High mobility group box 1 protein induction by Mycobacterium bovis BCG.

  Mediators of inflammation 20070101

• Platelet-induced growth of human fibroblasts is associated with an increased expression of 5-lipoxygenase.

  Thrombosis and haemostasis 20061101

• Identification and characterisation of a new class of highly specific and potent inhibitors of the mitochondrial pyruvate carrier.

  Biochimica et biophysica acta 20050101

• Two separate pathways for d-lactate oxidation by Saccharomyces cerevisiae mitochondria which differ in energy production and carrier involvement.

  Biochimica et biophysica acta 20040215

• D-Lactate transport and metabolism in rat liver mitochondria.

  The Biochemical journal 20020715

• Threonine metabolism in isolated rat hepatocytes.

  American journal of physiology. Endocrinology and metabolism 20011201