1012-05-1 | DL-Homophenylalanine

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$17.00	$12.00
5g	98%	in stock	$19.00	$14.00
10g	98%	in stock	$23.00	$17.00
25g	98%	in stock	$57.00	$40.00
100g	98%	in stock	$141.00	$99.00

Description

• Catalog Number: AA04911
• Chemical Name: DL-Homophenylalanine
• CAS Number: 1012-05-1
• Molecular Formula: C10H13NO2
• Molecular Weight: 179.2157
• MDL Number: MFCD00063092
• SMILES: NC(C(=O)O)CCc1ccccc1

Computed Properties

• Complexity: 164
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 4
• Undefined Atom Stereocenter Count: 1
• XLogP3: -1.2

Literature

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• Assessment of factors affecting micropropagation and ex vitro acclimatization of Nyctanthes arbor-tristis L.

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• The design of potent and selective inhibitors of DPP-4: optimization of ADME properties by amide replacements.

  Bioorganic & medicinal chemistry letters 20091115

• From lead to preclinical candidate: optimization of beta-homophenylalanine based inhibitors of dipeptidyl peptidase IV.

  Bioorganic & medicinal chemistry letters 20090815

• Discovery of beta-homophenylalanine based pyrrolidin-2-ylmethyl amides and sulfonamides as highly potent and selective inhibitors of dipeptidyl peptidase IV.

  Bioorganic & medicinal chemistry letters 20090801

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• Simultaneous synthesis of 2-phenylethanol and L-homophenylalanine using aromatic transaminase with yeast Ehrlich pathway.

  Biotechnology and bioengineering 20090401

• Asymmetrically simultaneous synthesis of L-homophenylalanine and N6-protected-2-oxo-6-amino-hexanoic acid by engineered Escherichia coli aspartate aminotransferase.

  Biotechnology progress 20090101

• A novel hydantoinase process using recombinant Escherichia coli cells with dihydropyrimidinase and L-N-carbamoylase activities as biocatalyst for the production of L-homophenylalanine.

  Journal of biotechnology 20080430

• Highly potent and selective substrate analogue factor Xa inhibitors containing D-homophenylalanine analogues as P3 residue: part 2.

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• mGluR7 undergoes rapid internalization in response to activation by the allosteric agonist AMN082.

  Neuropharmacology 20070101

• Structural-functional changes in detached cucumber leaves, and modelling these by hormone-treated leaf discs.

  Plant biology (Stuttgart, Germany) 20070101

• Expression and localization of calcium-dependent protein kinase isoforms in chickpea.

  Journal of plant physiology 20061101

• Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels.

  Bioorganic & medicinal chemistry letters 20060301

• Enantioselective synthesis of L-homophenylalanine by whole cells of recombinant Escherichia coli expressing L-aminoacylase and N-acylamino acid racemase genes from Deinococcus radiodurans BCRC12827.

  Biotechnology progress 20060101

• Activating cystic fibrosis transmembrane conductance regulator channels with pore blocker analogs.

  The Journal of biological chemistry 20050624

• Analogues of arginine vasopressin and its agonist and antagonist modified in the N-terminal part of the molecule with l-beta-homophenylalanine.

  The journal of peptide research : official journal of the American Peptide Society 20050401

• Asymmetrical synthesis of L-homophenylalanine using engineered Escherichia coli aspartate aminotransferase.

  Biotechnology progress 20050101

• In vitro micropropagation of Boswellia ovalifoliolata.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20050101

• Discovery of potent and selective beta-homophenylalanine based dipeptidyl peptidase IV inhibitors.

  Bioorganic & medicinal chemistry letters 20040920

• Enantioselective synthesis of (S)-2-amino-4-phenylbutanoic acid by the hydantoinase method.

  Chirality 20031001

• Conformationally-restricted analogues of efflux pump inhibitors that potentiate the activity of levofloxacin in Pseudomonas aeruginosa.

  Bioorganic & medicinal chemistry letters 20030818

• Asymmetric synthesis of L-homophenylalanine by equilibrium-shift using recombinant aromatic L-amino acid transaminase.

  Biotechnology and bioengineering 20030720

• Conformationally homogeneous cyclic tetrapeptides: useful new three-dimensional scaffolds.

  Journal of the American Chemical Society 20030122

• Kinetic study on the enzymatic resolution of homophenylalanine ester using ionic liquids.

  Biotechnology progress 20030101

• Regulation of Brassica rapa chloroplast proliferation in vivo and in cultured leaf disks.

  Protoplasma 20030101

• In vitro organogenesis and genetic transformation in popular Cucumis sativus L. through Agrobacterium tumefaciens.

  Indian journal of experimental biology 20020301

• Backbone modifications of aromatic peptide nucleic acid (APNA ) monomers and their hybridization properties with DNA and RNA.

  The Journal of organic chemistry 20010518