101257-38-9 | Thiazole-4-carbohydrazide

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$89.00	$62.00
1g	95%	in stock	$111.00	$78.00
5g	95%	in stock	$465.00	$325.00

Description

• Catalog Number: AA05105
• Chemical Name: Thiazole-4-carbohydrazide
• CAS Number: 101257-38-9
• Molecular Formula: C4H5N3OS
• Molecular Weight: 143.167
• MDL Number: MFCD00614363
• SMILES: NNC(=O)c1cscn1

Computed Properties

• Complexity: 118
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: -0.2

Upstream Synthesis Route

Thiazole-4-carbohydrazide is a versatile chemical compound widely used in chemical synthesis for its ability to serve as a key building block in the preparation of various organic molecules. This compound is commonly employed as a precursor in the synthesis of thiazole derivatives, which are important in medicinal chemistry for their diverse biological activities. Thiazole-4-carbohydrazide is particularly valued for its role in the creation of heterocyclic compounds with potential application in drug discovery and development. Its unique structure and reactivity make it a valuable tool for organic chemists seeking to access novel chemical entities with promising properties.

Literature

• Rational design of new antituberculosis agents: receptor-independent four-dimensional quantitative structure-activity relationship analysis of a set of isoniazid derivatives.

  Journal of medicinal chemistry 20040715