1013-22-5 | Piperazine, 1-(2,3-dimethylphenyl)-

Packsize	Purity	Availability	Price	Discounted Price
250mg		in stock	$16.00	$11.00
1g		in stock	$29.00	$20.00
5g		in stock	$83.00	$58.00
25g		in stock	$296.00	$207.00

Description

• Catalog Number: AA05204
• Chemical Name: Piperazine, 1-(2,3-dimethylphenyl)-
• CAS Number: 1013-22-5
• Molecular Formula: C12H18N2
• Molecular Weight: 190.2847
• MDL Number: MFCD00040730
• SMILES: Cc1c(C)cccc1N1CCNCC1

Computed Properties

• Complexity: 175
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 2.6

Upstream Synthesis Route

1-(2,3-Dimethylphenyl)piperazine is a versatile compound widely utilized in chemical synthesis for various applications. It serves as a valuable building block in the creation of complex organic molecules due to its unique structural properties. This compound is known for its ability to participate in a wide range of reactions, making it a valuable tool for chemists looking to synthesize novel compounds. In particular, 1-(2,3-Dimethylphenyl)piperazine is frequently employed in the pharmaceutical industry for the development of new drug candidates. Its incorporation into drug molecules can enhance their bioavailability, potency, and selectivity, leading to improved therapeutic outcomes. Additionally, this compound has found use in materials science, where it can be utilized to create functional materials with tunable properties. Overall, the application of 1-(2,3-Dimethylphenyl)piperazine in chemical synthesis enables the efficient and strategic construction of diverse molecular architectures with potential applications in various scientific fields.

Literature

• Endocannabinoids modulate non-adrenergic, non-cholinergic inhibitory neurotransmission in strips from the mouse gastric fundus.

  Acta physiologica (Oxford, England) 20120901

• Structure-activity relationships, ligand efficiency, and lipophilic efficiency profiles of benzophenone-type inhibitors of the multidrug transporter P-glycoprotein.

  Journal of medicinal chemistry 20120412

• 4-(o-Tol-yl)piperazin-1-ium chloride.

  Acta crystallographica. Section E, Structure reports online 20111101

• 1-(2,5-Dimethyl-phen-yl)piperazine-1,4-diium tetra-chloridozincate monohydrate.

  Acta crystallographica. Section E, Structure reports online 20110401

• 4-(2,3-Dimethyl-phen-yl)piperazin-1-ium chloride monohydrate.

  Acta crystallographica. Section E, Structure reports online 20080701

• Central and peripheral mechanisms of narcotic antitussives: codeine-sensitive and -resistant coughs.

  Cough (London, England) 20070101