10138-10-0 | Ethyl 4-oxobutanoate

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$339.00	$237.00
1g	95%	in stock	$649.00	$454.00
5g	95%	in stock	$2,576.00	$1,803.00

Description

• Catalog Number: AA05429
• Chemical Name: Ethyl 4-oxobutanoate
• CAS Number: 10138-10-0
• Molecular Formula: C6H10O3
• Molecular Weight: 130.1418
• MDL Number: MFCD01683413
• SMILES: CCOC(=O)CCC=O

Upstream Synthesis Route

Ethyl 4-oxobutanoate, also known as ethyl acetoacetate, plays a crucial role in chemical synthesis as a versatile building block. Due to its unique structure, this compound is widely utilized in the production of various pharmaceuticals, agrochemicals, and fine chemicals. Its keto group and ester functionality are key features that make it a valuable component in organic synthesis.One of the primary applications of ethyl 4-oxobutanoate is its role as a Michael acceptor in Michael addition reactions. This compound readily reacts with nucleophiles such as enolates, Grignard reagents, and amines, forming C-C bonds and enabling the creation of complex organic molecules. The resulting products can exhibit diverse chemical and biological activities, making ethyl 4-oxobutanoate a significant intermediate in the synthesis of biologically active compounds.Additionally, ethyl 4-oxobutanoate serves as a key precursor in the preparation of β-keto esters, which are essential intermediates in the synthesis of various pharmaceuticals, including statins and other drugs. Its ability to undergo decarboxylation and condensation reactions further expands its utility in the construction of heterocyclic compounds and natural product synthesis.Moreover, ethyl 4-oxobutanoate is employed in the development of chiral auxiliaries and asymmetric synthesis strategies. By incorporating this compound into the synthesis of chiral molecules, chemists can introduce stereochemical diversity and enhance the efficiency of their synthetic routes.Overall, ethyl 4-oxobutanoate's versatile reactivity and structural features make it a valuable tool in chemical synthesis, enabling the construction of complex molecules with diverse applications across various industries.