101555-62-8 | Fmoc-D-Pro-OH

Packsize	Purity	Availability	Price	Discounted Price
10g	97%	in stock	$12.00	$8.00
25g	97%	in stock	$15.00	$10.00
100g	97%	in stock	$56.00	$39.00

Description

• Catalog Number: AA05977
• Chemical Name: Fmoc-D-Pro-OH
• CAS Number: 101555-62-8
• Molecular Formula: C20H19NO4
• Molecular Weight: 337.3692
• MDL Number: MFCD00065671
• SMILES: OC(=O)[C@H]1CCCN1C(=O)OCC1c2ccccc2-c2c1cccc2

Computed Properties

• Complexity: 500
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 25
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 4
• XLogP3: 3.4

Upstream Synthesis Route

Fmoc-D-Pro-OH is a versatile and valuable building block in chemical synthesis, particularly in the field of peptide chemistry. Its unique structure, consisting of a D-proline amino acid with a fluorenylmethyloxycarbonyl (Fmoc) protecting group, serves various crucial functions in peptide synthesis.One of the key applications of Fmoc-D-Pro-OH lies in its use as a chiral building block for constructing peptide chains with specific three-dimensional structures. The incorporation of D-proline at strategic positions in a peptide sequence can confer increased stability, conformational rigidity, and enhanced biological activity to the resulting peptide product.Furthermore, the Fmoc protecting group plays a critical role in peptide synthesis by selectively blocking the amino group of D-proline, thus allowing for controlled and sequential deprotection and coupling steps during peptide assembly. This enables chemists to efficiently and selectively synthesize complex peptides with high purity and yield.Overall, Fmoc-D-Pro-OH is an indispensable tool for chemists engaged in the synthesis of bioactive peptides, pharmaceuticals, and other peptide-based materials, offering precise control over stereochemistry and conformation in the design of novel peptide structures.