102-93-2 | 3-Phenyl-propionamide

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$11.00	$8.00
1g	97%	in stock	$15.00	$11.00
5g	97%	in stock	$42.00	$30.00
10g	97%	in stock	$73.00	$52.00
100g	97%	in stock	$572.00	$400.00

Description

• Catalog Number: AA07908
• Chemical Name: 3-Phenyl-propionamide
• CAS Number: 102-93-2
• Molecular Formula: C9H11NO
• Molecular Weight: 149.1897
• MDL Number: MFCD00025535
• SMILES: NC(=O)CCc1ccccc1
• NSC Number: 229316

Computed Properties

• Complexity: 128
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 3
• XLogP3: 0.9

Upstream Synthesis Route

3-Phenylpropanamide, also known as phenylpropionamide, is a versatile compound widely utilized in chemical synthesis for various applications. In the realm of organic chemistry, 3-Phenylpropanamide serves as a crucial building block in the creation of numerous pharmaceuticals, agrochemicals, and fine chemicals. Its structural composition, characterized by a phenyl group attached to a propionamide moiety, imparts unique reactivity and properties that make it indispensable in synthetic routes.One prominent application of 3-Phenylpropanamide lies in the synthesis of pharmaceutical intermediates. Its presence as a key precursor enables the production of diverse therapeutic agents targeting a range of medical conditions, including pain management, neurological disorders, and cardiovascular diseases. Through strategic chemical transformations, 3-Phenylpropanamide can be converted into complex structures essential for the development of active pharmaceutical ingredients with potent biological activities.Furthermore, in the field of agrochemicals, 3-Phenylpropanamide plays a vital role in the synthesis of pesticides, herbicides, and fungicides. By incorporating this compound into the molecular design of agricultural chemicals, researchers can enhance their efficacy, selectivity, and environmental impact. The versatility of 3-Phenylpropanamide enables the modification of its chemical structure to optimize performance characteristics, such as bioavailability, persistence, and target specificity, in crop protection products.Moreover, 3-Phenylpropanamide finds utility in the creation of fine chemicals used in various industrial applications. Its participation in intricate synthetic pathways leads to the production of specialty compounds utilized in flavors, fragrances, dyes, and materials science. The ability to functionalize the phenylpropionamide framework enables the generation of molecules with tailored properties, catering to the specific needs of diverse industries seeking high-quality intermediates for further processing.Overall, 3-Phenylpropanamide serves as a fundamental component in chemical synthesis, facilitating the construction of valuable compounds with wide-ranging applications in pharmaceuticals, agrochemicals, and fine chemicals. Its pivotal role as a versatile building block underscores its significance in driving innovation and advancement across multiple sectors of the chemical industry.

Literature

• Design, synthesis, and biological evaluation of phenylpropanamides as novel transient receptor potential vanilloid 1 antagonists.

  Archives of pharmacal research 20090901

• One-pot synthesis of benzylacetamide from oxime under ultrasound irradiation.

  Ultrasonics sonochemistry 20090601

• Alkylamine sensing using langmuir-blodgett films of n-alkyl-N-phenylamide-substituted zinc porphyrins.

  The journal of physical chemistry. B 20080911

• (S)-1,5-Dibenzyl-3-tert-butyl-imidazol-idin-4-one.

  Acta crystallographica. Section E, Structure reports online 20080701

• Design and synthesis of 3-arylpyrrolidine-2-carboxamide derivatives as melanocortin-4 receptor ligands.

  Bioorganic & medicinal chemistry letters 20080315

• Aromatic chlorination of omega-phenylalkylamines and omega-phenylalkylamides in carbon tetrachloride and alpha,alpha,alpha-trifluorotoluene.

  Organic & biomolecular chemistry 20060721

• Search for constituents with neurotrophic factor-potentiating activity from the medicinal plants of paraguay and Thailand.

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20040701

• Design and synthesis of highly potent benzodiazepine gamma-secretase inhibitors: preparation of (2S,3R)-3-(3,4-difluorophenyl)-2-(4-fluorophenyl)-4- hydroxy-N-((3S)-1-methyl-2-oxo-5- phenyl-2,3-dihydro-1H-benzo[e][1,4]-diazepin-3-yl)butyramide by use of an asymmetric Ireland-Claisen rearrangement.

  Journal of medicinal chemistry 20030605

• Update on medical treatment of ejaculatory disorders.

  International journal of andrology 20021201