1020149-73-8 | SGI-1027

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$28.00	$19.00
5mg	98%	in stock	$67.00	$47.00
10mg	98%	in stock	$107.00	$75.00
50mg	98%	in stock	$339.00	$238.00
100mg	98%	in stock	$422.00	$295.00

Description

• Catalog Number: AA08004
• Chemical Name: SGI-1027
• CAS Number: 1020149-73-8
• Molecular Formula: C27H23N7O
• Molecular Weight: 461.5178
• MDL Number: MFCD27937047
• SMILES: Cc1cc(Nc2ccc(cc2)NC(=O)c2ccc(cc2)Nc2ccnc3c2cccc3)nc(n1)N

Computed Properties

• Complexity: 676
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 35
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 6
• XLogP3: 4.8

Upstream Synthesis Route

The compound N-[4-[(2-amino-6-methyl-4-pyrimidinyl)amino]phenyl]-4-(4-quinolinylamino)benzamide, also known as $name$, is commonly used in chemical synthesis as a versatile building block. This molecule plays a crucial role in forming complex structures and functional groups in the field of organic chemistry. Its unique structure allows for selective reactions and precise control over the formation of new compounds. As a key intermediate in synthetic pathways, $name$ is utilized for the synthesis of various pharmaceuticals, agrochemicals, and materials with specific properties. Its strategic placement in a synthetic scheme enables the efficient production of target molecules with desired characteristics, making it an essential component in modern chemical synthesis strategies.

Literature

• New insights on the mechanism of quinoline-based DNA Methyltransferase inhibitors.

  The Journal of biological chemistry 20150306

• Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells.

  Journal of medicinal chemistry 20140213

• Laccaic acid A is a direct, DNA-competitive inhibitor of DNA methyltransferase 1.

  The Journal of biological chemistry 20130816