102082-89-3 | 2,6-Difluorocinnamic acid

Packsize	Purity	Availability	Price	Discounted Price
10g	98%	in stock	$12.00	$9.00
25g	98%	in stock	$14.00	$10.00

Description

• Catalog Number: AA08364
• Chemical Name: 2,6-Difluorocinnamic acid
• CAS Number: 102082-89-3
• Molecular Formula: C9H6F2O2
• Molecular Weight: 184.1395
• MDL Number: MFCD00010319
• SMILES: OC(=O)/C=C/c1c(F)cccc1F

Computed Properties

• Complexity: 206
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• XLogP3: 2.1

Upstream Synthesis Route

Trans-2,6-Difluorocinnamic acid is a versatile chemical compound utilized in chemical synthesis processes for its unique properties and reactivity. As a bifunctional molecule, it serves as an important building block for the synthesis of various organic compounds. Due to the presence of the difluoro group at specific positions on the cinnamic acid backbone, trans-2,6-Difluorocinnamic acid exhibits enhanced stability and distinct reactivity compared to its non-fluorinated counterparts.In chemical synthesis, trans-2,6-Difluorocinnamic acid is commonly employed in the preparation of fluorinated pharmaceuticals, agrochemicals, and advanced materials. Its fluorinated structure imparts desirable characteristics such as increased lipophilicity, improved bioavailability, and enhanced biological activity to the final products. The presence of the difluoro group also enables selective functionalization at the fluorinated positions, offering greater control over the chemical reactions and facilitating the synthesis of complex molecules with high precision.Furthermore, trans-2,6-Difluorocinnamic acid can participate in various synthetic transformations including cross-coupling reactions, Heck reactions, and Suzuki-Miyaura couplings, allowing for the introduction of diverse functional groups into the molecular framework. Its compatibility with a wide range of reaction conditions and reagents makes it a valuable tool for the construction of versatile molecular scaffolds in organic synthesis.Overall, the application of trans-2,6-Difluorocinnamic acid in chemical synthesis enables the efficient and strategic construction of fluorinated organic compounds with tailored properties and functionalities.