10212-20-1 | 2'-Deoxy-2'-fluorocytidine

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$15.00	$11.00
1g	95%	in stock	$35.00	$25.00
5g	97%	in stock	$122.00	$86.00
25g	97%	in stock	$449.00	$315.00

Description

• Catalog Number: AA08465
• Chemical Name: 2'-Deoxy-2'-fluorocytidine
• CAS Number: 10212-20-1
• Molecular Formula: C9H12FN3O4
• Molecular Weight: 245.2077
• MDL Number: MFCD00057445
• SMILES: OC[C@H]1O[C@H]([C@@H]([C@@H]1O)F)n1ccc(nc1=O)N

Computed Properties

• Complexity: 386
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 4
• Heavy Atom Count: 17
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 2
• XLogP3: -1.1

Literature

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  Antiviral research 20111101

• Synthesis and anti-HCV activity of 3',4'-oxetane nucleosides.

  Bioorganic & medicinal chemistry letters 20100801

• Simultaneous quantification of 2',2'-difluorodeoxycytidine and 2',2'-difluorodeoxyuridine nucleosides and nucleotides in white blood cells using porous graphitic carbon chromatography coupled with tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20091001

• Design, synthesis, and antiviral properties of 4'-substituted ribonucleosides as inhibitors of hepatitis C virus replication: the discovery of R1479.

  Bioorganic & medicinal chemistry letters 20070501

• Inhibition of hepatitis C replicon RNA synthesis by beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine: a specific inhibitor of hepatitis C virus replication.

  Antiviral chemistry & chemotherapy 20060101

• Design, synthesis, and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methylcytidine, a potent inhibitor of hepatitis C virus replication.

  Journal of medicinal chemistry 20050825

• Synthesis and anti-viral activity of a series of d- and l-2'-deoxy-2'-fluororibonucleosides in the subgenomic HCV replicon system.

  Bioorganic & medicinal chemistry 20050301

• Synthesis of some 2'-fluoro-2'-deoxy-3'-C-ethynyl and 3'-C-vinyl-beta-D-lyxofuranosyl nucleosides.

  Nucleosides, nucleotides & nucleic acids 20050101

• Inhibition of the subgenomic hepatitis C virus replicon in huh-7 cells by 2'-deoxy-2'-fluorocytidine.

  Antimicrobial agents and chemotherapy 20040201

• Measurement of the anti-cancer agent gemcitabine in human plasma by high-performance liquid chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030225

• A new class of Spiegelmers containing 2'-fluoro-nucleotides.

  Nucleosides, nucleotides & nucleic acids 20030101

• Quantification of 2'-fluoro-2'-deoxyuridine and 2'-fluoro-2'-deoxycytidine in DNA and RNA isolated from rats and woodchucks using LC/MS/MS.

  Chemical research in toxicology 20020701

• Nucleosides. 110. Synthesis and antiherpes virus activity of some 2'-fluoro-2'-deoxyarabinofuranosylpyrimidine nucleosides.

  Journal of medicinal chemistry 19790101