1021868-08-5 | 5-(tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$11.00	$8.00
1g	98%	in stock	$34.00	$24.00
2.5g	98%	in stock	$85.00	$60.00
5g	98%	in stock	$153.00	$108.00

Description

• Catalog Number: AA08644
• Chemical Name: 5-(tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline
• CAS Number: 1021868-08-5
• Molecular Formula: C15H18BNO2
• Molecular Weight: 255.1199
• MDL Number: MFCD22418302
• SMILES: CC1(C)OB(OC1(C)C)c1cccc2c1cccn2

Computed Properties

• Complexity: 329
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 19
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1

Upstream Synthesis Route

5-Quinolineboronic Acid Pinacol Ester is a versatile compound widely utilized in chemical synthesis as a key building block for the formation of various organic molecules. This compound is particularly valuable in the field of medicinal chemistry, where it serves as a crucial intermediate in the synthesis of pharmaceutical drugs.One of the primary applications of 5-Quinolineboronic Acid Pinacol Ester is its role in Suzuki-Miyaura cross-coupling reactions. This powerful catalytic process allows for the selective and efficient formation of carbon-carbon bonds, enabling the synthesis of complex organic molecules with high precision. By serving as a boronate ester source in this reaction, 5-Quinolineboronic Acid Pinacol Ester plays a pivotal role in the construction of biaryl compounds, which are prevalent in numerous pharmaceuticals and agrochemicals.Additionally, 5-Quinolineboronic Acid Pinacol Ester can be employed in palladium-catalyzed coupling reactions, such as Buchwald-Hartwig amination and Heck reactions, to introduce nitrogen and carbon functionalities, respectively, into organic molecules. These transformations are crucial for the preparation of structurally diverse compounds with unique properties and biological activities.Furthermore, 5-Quinolineboronic Acid Pinacol Ester finds application in the synthesis of heterocyclic compounds, which are prevalent in drug discovery and development. Its ability to undergo various functionalization reactions, including halogenation, arylation, and alkylation, makes it a valuable tool for the construction of diverse molecular scaffolds.Overall, the strategic incorporation of 5-Quinolineboronic Acid Pinacol Ester in chemical synthesis enables the efficient and cost-effective synthesis of complex organic molecules with important applications across multiple scientific disciplines, particularly in drug discovery and material science.