1025113-78-3 | Potassium 5-formylthiophene-2-trifluoroborate

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$19.00	$13.00
1g	95%	in stock	$32.00	$22.00
5g	95%	in stock	$83.00	$58.00
25g	95%	in stock	$413.00	$289.00

Description

• Catalog Number: AA09683
• Chemical Name: Potassium 5-formylthiophene-2-trifluoroborate
• CAS Number: 1025113-78-3
• Molecular Formula: C5H3BF3KOS
• Molecular Weight: 218.0462
• MDL Number: MFCD09800740
• SMILES: O=Cc1ccc(s1)[B-](F)(F)F.[K+]

Computed Properties

• Complexity: 165
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1

Upstream Synthesis Route

Potassium trifluoro(5-formylthiophen-2-yl)borate, a versatile organoboron compound, finds a crucial application in chemical synthesis as a powerful reagent for various organic transformations. This unique compound serves as a key building block in the synthesis of complex organic molecules through various reactions. With its boron functionality and trifluoromethyl group, it exhibits strong nucleophilic behavior, enabling it to participate in numerous carbon-carbon and carbon-heteroatom bond formation reactions.In organic synthesis, Potassium trifluoro(5-formylthiophen-2-yl)borate contributes to the construction of heterocyclic compounds, particularly those containing thiophene moieties. Its reactivity makes it a valuable tool in the formation of aryl boronates, which are essential intermediates in Suzuki-Miyaura cross-coupling reactions. Additionally, this compound facilitates the introduction of the trifluoromethyl group into organic molecules, a strategy commonly utilized in medicinal chemistry, agrochemicals, and materials science.Furthermore, Potassium trifluoro(5-formylthiophen-2-yl)borate demonstrates remarkable compatibility with a wide array of functional groups, allowing chemists to incorporate it into diverse synthetic routes with high efficiency and selectivity. Its strategic use in the preparation of pharmaceuticals, natural products, and advanced materials illustrates its significance in modern organic synthesis strategies.

Literature

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501