1025718-91-5 | 3-(Methoxycarbonyl)pyridine-5-boronic acid, pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$58.00	$41.00
5g	98%	in stock	$227.00	$159.00
10g	98%	in stock	$395.00	$277.00
25g	98%	in stock	$775.00	$543.00
100g	98%	in stock	$2,314.00	$1,620.00

Description

• Catalog Number: AA09898
• Chemical Name: 3-(Methoxycarbonyl)pyridine-5-boronic acid, pinacol ester
• CAS Number: 1025718-91-5
• Molecular Formula: C13H18BNO4
• Molecular Weight: 263.0973
• MDL Number: MFCD09027079
• SMILES: COC(=O)c1cncc(c1)B1OC(C(O1)(C)C)(C)C

Computed Properties

• Complexity: 343
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 19
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3

Upstream Synthesis Route

Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinate is a versatile compound that finds significant utility in chemical synthesis, particularly in the realm of organic chemistry. This compound serves as a valuable building block for the construction of various complex molecules through cross-coupling reactions.In the field of organic synthesis, Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinate is commonly employed as a precursor in Suzuki-Miyaura cross-coupling reactions. This reaction represents a powerful method for the formation of carbon-carbon bonds, crucial for the creation of diverse organic compounds. By utilizing this compound as a starting material, chemists can efficiently introduce the nicotinate moiety into target molecules, thereby enabling the synthesis of novel pharmaceuticals, agrochemicals, and materials with tailored properties.Moreover, the presence of the boron moiety in Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinate enhances its reactivity and compatibility in various palladium-catalyzed coupling reactions. This feature expands the synthetic possibilities, allowing for the selective functionalization of specific positions within the molecule and facilitating the construction of intricate molecular architectures.Overall, the application of Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinate in chemical synthesis underscores its significance as a valuable tool for organic chemists seeking to access novel compounds and advance the frontiers of chemical research.