10261-82-2 | 1,5-Naphthyridin-2(1H)-one

Packsize	Purity	Availability	Price	Discounted Price
100mg	97%	in stock	$36.00	$25.00
250mg	97%	in stock	$55.00	$38.00
1g	97%	in stock	$139.00	$97.00
5g	97%	in stock	$387.00	$271.00
10g	97%	in stock	$667.00	$467.00
25g	97%	in stock	$1,319.00	$923.00

Description

• Catalog Number: AA10053
• Chemical Name: 1,5-Naphthyridin-2(1H)-one
• CAS Number: 10261-82-2
• Molecular Formula: C8H6N2O
• Molecular Weight: 146.146
• MDL Number: MFCD11877925
• SMILES: O=c1ccc2c([nH]1)cccn2

Computed Properties

• Complexity: 200
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• XLogP3: 0.3

Upstream Synthesis Route

1,5-Naphthyridin-2(1H)-one, also known as naphthyridinone, is a versatile compound widely used in chemical synthesis. Its unique structure and reactivity make it an essential building block for creating a variety of organic compounds.In chemical synthesis, 1,5-Naphthyridin-2(1H)-one serves as a key intermediate in the production of pharmaceuticals, agrochemicals, and specialty chemicals. Its heterocyclic nature allows it to participate in a range of reactions, including nucleophilic substitutions, oxidative transformations, and metal-catalyzed coupling reactions.One of the main applications of 1,5-Naphthyridin-2(1H)-one is in the synthesis of bioactive compounds. By functionalizing the naphthyridinone core, chemists can create molecules with potential therapeutic properties, such as antibacterial, antiviral, and anticancer activities. Additionally, its rigid structure and aromatic character make it a valuable scaffold for designing new drug candidates with improved biological profiles.Furthermore, 1,5-Naphthyridin-2(1H)-one can be modified to introduce diverse functional groups, allowing for the creation of chemical libraries for drug discovery and development. Its ability to undergo selective transformations under mild conditions makes it a highly valuable building block for medicinal chemistry and materials science research.Overall, 1,5-Naphthyridin-2(1H)-one plays a crucial role in the field of chemical synthesis, enabling the efficient construction of complex molecules with diverse applications in drug design, materials science, and agrochemical development.

Literature

• High-Dimensional descriptor selection and computational QSAR modeling for antitumor activity of ARC-111 analogues Based on Support Vector Regression (SVR).

  International journal of molecular sciences 20120101