103-29-7 | Bibenzyl

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$13.00	$9.00
1g	98%	in stock	$15.00	$10.00
5g	98%	in stock	$16.00	$11.00
25g	98%	in stock	$20.00	$14.00
100g	98%	in stock	$55.00	$38.00
500g	98%	in stock	$95.00	$66.00

Description

• Catalog Number: AB57152
• Chemical Name: Bibenzyl
• CAS Number: 103-29-7
• Molecular Formula: C14H14
• Molecular Weight: 182.261
• MDL Number: MFCD00004796
• SMILES: c1ccc(cc1)CCc1ccccc1

Computed Properties

• Complexity: 120
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 14
• Rotatable Bond Count: 3
• XLogP3: 4.8

Upstream Synthesis Route

1,2-Diphenylethane, also known as ethyldiphenylmethane, is a versatile organic compound commonly used in chemical synthesis. Due to its unique chemical structure, 1,2-Diphenylethane serves as a crucial building block for the creation of various complex organic molecules. One of the primary applications of 1,2-Diphenylethane in chemical synthesis is in the formation of diaryl sulfides. By reacting 1,2-Diphenylethane with sulfur compounds under specific conditions, chemists can efficiently produce diaryl sulfides, which are essential intermediates in the synthesis of pharmaceuticals, agrochemicals, and materials science.Furthermore, 1,2-Diphenylethane can also be utilized to create biaryl compounds through transition metal-catalyzed cross-coupling reactions. These biaryl compounds play a significant role in medicinal chemistry and materials science, serving as key structural motifs in various active pharmaceutical ingredients and functional materials.In summary, 1,2-Diphenylethane is a valuable chemical building block that enables the efficient synthesis of diverse organic compounds, making it an indispensable component in modern chemical research and industrial applications.

Literature

• Agonistic effects of diverse xenobiotics on the constitutive androstane receptor as detected in a recombinant yeast-cell assay.

  Toxicology in vitro : an international journal published in association with BIBRA 20180201

• Novel aminobenzyl-acetamidine derivative modulate the differential regulation of NOSs in LPS induced inflammatory response: role of PI3K/Akt pathway.

  Biochimica et biophysica acta 20121201

• Zirconium catalyzed alkyne dimerization for selective Z-enyne synthesis.

  Chemical communications (Cambridge, England) 20121107

• Marchantin A, a macrocyclic bisbibenzyl ether, isolated from the liverwort Marchantia polymorpha, inhibits protozoal growth in vitro.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20121015

• Diastereoselective additions of titanium enolates from N-glycolyl thiazolidinethiones to acetals.

  The Journal of organic chemistry 20121005

• Design, synthesis and molecular simulation studies of dihydrostilbene derivatives as potent tyrosinase inhibitors.

  Bioorganic & medicinal chemistry letters 20120901

• Synthesis of U(IV) imidos from Tp*2U(CH2Ph) (Tp* = hydrotris(3,5-dimethylpyrazolyl)borate) by extrusion of bibenzyl.

  Dalton transactions (Cambridge, England : 2003) 20120714

• Chrysotoxine, a novel bibenzyl compound selectively antagonizes MPP⁺, but not rotenone, neurotoxicity in dopaminergic SH-SY5Y cells.

  Neuroscience letters 20120711

• The ESI CAD fragmentations of protonated 2,4,6-tris(benzylamino)- and tris(benzyloxy)-1,3,5-triazines involve benzyl-benzyl interactions: a DFT study.

  Journal of mass spectrometry : JMS 20120701

• Synthesis of a uranium(VI)-carbene: reductive formation of uranyl(V)-methanides, oxidative preparation of a [R2C═U═O]2+ analogue of the [O═U═O]2+ uranyl ion (R = Ph2PNSiMe3), and comparison of the nature of U(IV)═C, U(V)═C, and U(VI)═C double bonds.

  Journal of the American Chemical Society 20120620

• Conformational mobility of small molecules in glass-forming solutions studied by FTIR spectroscopy.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120601

• Intramolecular charge resonance in dimer radical anions of di-, tri-, tetra-, and pentaphenylalkanes.

  The Journal of organic chemistry 20120601

• Triazole phosphohistidine analogues compatible with the Fmoc-strategy.

  Organic & biomolecular chemistry 20120528

• Carbon-carbon reductive elimination from homoleptic uranium(IV) alkyls induced by redox-active ligands.

  Journal of the American Chemical Society 20120411

• Antimicrobial constituents from the tubers of Bletilla ochracea.

  Planta medica 20120401

• 5-{2-(4-Chloro-phen-yl)-1-[2-(4-chloro-phen-yl)-1-(3,4,5-trimeth-oxy-phen-yl)eth-oxy]eth-yl}-1,2,3-trimeth-oxy-benzene.

  Acta crystallographica. Section E, Structure reports online 20120401

• Contribution of phosphates and adenine to the potency of adenophostins at the IP₃ receptor: synthesis of all possible bisphosphates of adenophostin A.

  Journal of medicinal chemistry 20120223

• A new minor dimmeric ester from seeds of Cassia fistula L. (Leguminosae).

  Natural product research 20120101

• New antioxidant bibenzyl derivative and isoflavonoid from the Tunisian Salsola tetrandra Folsk.

  Natural product research 20120101

• Baicalein antagonizes rotenone-induced apoptosis in dopaminergic SH-SY5Y cells related to Parkinsonism.

  Chinese medicine 20120101

• Dehydrocostuslactone suppresses angiogenesis in vitro and in vivo through inhibition of Akt/GSK-3β and mTOR signaling pathways.

  PloS one 20120101

• Chemical clearing and dehydration of GFP expressing mouse brains.

  PloS one 20120101

• Investigation of the biosynthetic potential of endophytes in traditional Chinese anticancer herbs.

  PloS one 20120101

• [Antitumoral bibenzyl derivatives from tuber of Arundina graminifolia].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120101

• Milled wood lignin: a linear oligomer.

  Biomacromolecules 20111114

• Phenolic compounds from the rhizomes of Dioscorea bulbifera.

  Chemistry & biodiversity 20111101

• 2-[2-(2,4-Dinitro-phen-yl)eth-yl]-1,3,5-trinitro-benzene.

  Acta crystallographica. Section E, Structure reports online 20111101

• Biosynthesis of the major tetrahydroxystilbenes in spruce, astringin and isorhapontin, proceeds via resveratrol and is enhanced by fungal infection.

  Plant physiology 20111001

• Unsurpassed cage effect for the photolysis of dibenzyl ketones in water-soluble dendrimers.

  Organic & biomolecular chemistry 20110921

• o-Carborane as an electron-transfer mediator in electrocatalytic reduction.

  Chemical communications (Cambridge, England) 20110814

• Calix[4]arene-based 1,3-diconjugate of salicylyl imine having dibenzyl amine moiety (L): synthesis, characterization, receptor properties toward Fe2+, Cu2+, and Zn2+, crystal structures of its Zn2+ and Cu2+ complexes, and selective phosphate sensing by the [ZnL].

  Inorganic chemistry 20110801

• Concomitant polymorphism in the stereoselective synthesis of a β-benzyl-β-hydroxyaspartate analogue.

  Acta crystallographica. Section C, Crystal structure communications 20110801

• 1,3-Dibenzyl-5-chloro-1H-benzimidazol-2(3H)-one.

  Acta crystallographica. Section E, Structure reports online 20110801

• Role of the low-energy excited states in the radiolysis of aromatic liquids.

  The journal of physical chemistry. A 20110707

• Selective inhibition of iNOS by benzyl- and dibenzyl derivatives of N-(3-aminobenzyl)acetamidine.

  ChemMedChem 20110704

• Extracellular nucleotides affect pericyte-mediated regulation of rat in situ vasa recta diameter.

  Acta physiologica (Oxford, England) 20110701

• 2,6-Anhydro-1,3-di-O-benzyl-d-mannitol.

  Acta crystallographica. Section E, Structure reports online 20110701

• Complete NMR data of methoxylated cis- and trans-stilbenes as well as 1,2-diphenylethanes.

  Magnetic resonance in chemistry : MRC 20110601

• Synthesis and evaluation of bibenzyl glycosides as potent tyrosinase inhibitors.

  European journal of medicinal chemistry 20110401

• Antioxidant bibenzyl derivatives from Notholaena nivea Desv.

  Molecules (Basel, Switzerland) 20110317

• The multiple personalities of Watson and Crick strands.

  Biology direct 20110101

• Syntheses of secocyclolignanes and comparative antioxidative activity between secocyclolignane and the dibenzyl type of lignan.

  Bioscience, biotechnology, and biochemistry 20110101

• In vitro antioxidant of a water-soluble polysaccharide from Dendrobium fimhriatum Hook.var.oculatum Hook.

  International journal of molecular sciences 20110101

• A new bibenzyl from Dendrobium secundum.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20110101

• In vitro erythrocytic membrane effects of dibenzyl trisulfide, a secondary metabolite of Petiveria alliacea.

  Fitoterapia 20101201

• Chrysotoxine, a novel bibenzyl compound, inhibits 6-hydroxydopamine induced apoptosis in SH-SY5Y cells via mitochondria protection and NF-κB modulation.

  Neurochemistry international 20101101

• Life's immunity as a normal distribution function: philosophies for the use of dibenzyl trisulphide in immunity enhancement and life extension.

  The West Indian medical journal 20101001

• Functional groups and sulfur K-edge XANES spectra: divalent sulfur and disulfides.

  The journal of physical chemistry. A 20100909

• Heme oxygenase inhibition by 1-aryl-2-(1h-imidazol-1-yl/1h-1,2,4-triazol-1-yl)ethanones and their derivatives.

  ChemMedChem 20100903

• Moscatilin, a bibenzyl derivative from the India orchid Dendrobrium loddigesii, suppresses tumor angiogenesis and growth in vitro and in vivo.

  Cancer letters 20100628

• Radical reactivity of aza[60]fullerene: preparation of monoadducts and limitations.

  The Journal of organic chemistry 20100618

• Zirconium enolatoimine complexes in olefin polymerization.

  Dalton transactions (Cambridge, England : 2003) 20100521

• Marchantin A, a cyclic bis(bibenzyl ether), isolated from the liverwort Marchantia emarginata subsp. tosana induces apoptosis in human MCF-7 breast cancer cells.

  Cancer letters 20100501

• Alkylresorcinol synthases expressed in Sorghum bicolor root hairs play an essential role in the biosynthesis of the allelopathic benzoquinone sorgoleone.

  The Plant cell 20100301

• Dibenzyl 3,3'-diethyl-4,4'-dimethyl-2,2'-methylenebis(pyrrole-5-carboxylate).

  Acta crystallographica. Section E, Structure reports online 20100301

• Syntheses and structures of zirconium(IV) complexes supported by 2,6-di-adamantylaryloxide ligands and formation of arene-bridged dizirconium complexes with an inverse sandwich structure.

  Dalton transactions (Cambridge, England : 2003) 20100114

• Lanthanide tri-benzyl complexes: structural variations and useful precursors to phosphorus-stabilised lanthanide carbenes.

  Dalton transactions (Cambridge, England : 2003) 20100114

• Antioxidant biomarkers from Vanda coerulea stems reduce irradiated HaCaT PGE-2 production as a result of COX-2 inhibition.

  PloS one 20100101

• Hydroperoxylation by hydroxyethylphosphonate dioxygenase.

  Journal of the American Chemical Society 20091111

• Vertical flow soil filter for the elimination of micro pollutants from storm and waste water.

  Chemosphere 20091101

• Implications of dibenzyl trisulphide for disease treatment based on its mode of action.

  The West Indian medical journal 20091101

• Zirconium complex of an [OSSO]-type diphenolate ligand bearing trans-1,2-cyclooctanediylbis(thio) core: synthesis, structure, and isospecific 1-hexene polymerization.

  Journal of the American Chemical Society 20090930

• Bibenzyl- and stilbene-core compounds with non-polar linker atom substituents as selective ligands for estrogen receptor beta.

  European journal of medicinal chemistry 20090901

• Four new bibenzyl derivatives from Dendrobium candidum.

  Chemical & pharmaceutical bulletin 20090901

• An updated review of tyrosinase inhibitors.

  International journal of molecular sciences 20090601

• New bibenzyl derivatives from the tubers of Pleione yunnanensis.

  Chemical & pharmaceutical bulletin 20090501

• Computational study of bond dissociation enthalpies for lignin model compounds. Substituent effects in phenethyl phenyl ethers.

  The Journal of organic chemistry 20090403

• Alkaline reforming of brominated fire-retardant plastics: fate of bromine and antimony.

  Chemosphere 20090201

• Three new bibenzyl derivatives from Dendrobium candidum.

  Chemical & pharmaceutical bulletin 20090201

• Bis(2-bromo-benz-yl) tris-ulfide.

  Acta crystallographica. Section E, Structure reports online 20090201

• Highly regioselective derivatization of trimetallic nitride templated endohedral metallofullerenes via a facile photochemical reaction.

  Journal of the American Chemical Society 20081231

• Optical emission study of radio-frequency excited toluene plasma.

  The journal of physical chemistry. A 20081225

• Novel high-affinity and selective biaromatic 4-substituted gamma-hydroxybutyric acid (GHB) analogues as GHB ligands: design, synthesis, and binding studies.

  Journal of medicinal chemistry 20081225

• Induction of apoptosis by a synergistic lignan composition from Cedrus deodara in human cancer cells.

  Phytotherapy research : PTR 20081201

• Molecular design of potent tyrosinase inhibitors having the bibenzyl skeleton.

  Bioorganic & medicinal chemistry letters 20081001

• Insight into the mechanisms of the ethylbenzene disproportionation: transition state shape selectivity on zeolites.

  Journal of the American Chemical Society 20080924

• Entrapment of an organometallic complex within a metal: a concept for heterogeneous catalysis.

  Journal of the American Chemical Society 20080910

• Anti-Markovnikov hydroarylation of styrenes catalyzed by an in situ generated ruthenium complex.

  Chemical communications (Cambridge, England) 20080907

• Enantiomerically pure titanium complexes containing an [OSSO]-type bis(phenolate) ligand: synthesis, structure, and formation of optically active oligostyrenes.

  Chemistry, an Asian journal 20080901

• Photolysis of dibenzyl ketones sorbed on MFI zeolites in the presence of spectator molecules: cage effects, kinetics, and external surface sites characterization.

  Journal of the American Chemical Society 20080827

• Synthesis of a tetrasaccharide phosphate from the linkage region of the arabinogalactan-peptidoglycan complex in the mycobacterial cell wall.

  Carbohydrate research 20080721

• Five new compounds from Dendrobium longicornu.

  Planta medica 20080401

• Synthesis and characterization of polyketanils with 3,8-diamino-6-phenylphenanthridine moieties exhibiting light emitting properties molecular and supramolecular engineering concept.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080201

• Glucocorticoid receptor antagonists.

  Current topics in medicinal chemistry 20080101

• Petiveria alliacea extracts uses multiple mechanisms to inhibit growth of human and mouse tumoral cells.

  BMC complementary and alternative medicine 20080101

• Dibenzyl penta-thio-dicarbonate.

  Acta crystallographica. Section E, Structure reports online 20080101

• Dibenzyl 3,3',4,4'-tetra-methyl-5,5'-(ethynedi-yl)bis-(pyrrole-2-carboxyl-ate).

  Acta crystallographica. Section E, Structure reports online 20080101

• Singlet oxygen promoted carbon-heteroatom bond cleavage in dibenzyl sulfides and tertiary dibenzylamines. Structural effects and the role of exciplexes.

  The Journal of organic chemistry 20071207

• Bioactive polychlorinated bibenzyls from the liverwort Riccardia polyclada.

  Journal of natural products 20071201

• Group 4 complexes of a new [OSSO]-type dianionic ligand. Coordination chemistry and preliminary polymerization catalysis studies.

  Inorganic chemistry 20071001

• A para-hydrogen investigation of palladium-catalyzed alkyne hydrogenation.

  Journal of the American Chemical Society 20070523

• Bioactive compounds from Bauhinia purpurea possessing antimalarial, antimycobacterial, antifungal, anti-inflammatory, and cytotoxic activities.

  Journal of natural products 20070501

• Complete dechlorination of DDE/DDD using magnesium/palladium system.

  Water environment research : a research publication of the Water Environment Federation 20070401

• Couplings of benzylic halides mediated by titanocene chloride: synthesis of bibenzyl derivatives.

  The Journal of organic chemistry 20070316

• Studies on dechlorination of DDT (1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane) using magnesium/palladium bimetallic system.

  Journal of hazardous materials 20070102

• Bioactive bibenzyl derivatives and fluorenones from Dendrobium nobile.

  Journal of natural products 20070101

• A critical review of the therapeutic potential of dibenzyl trisulphide isolated from Petiveria alliacea L (guinea hen weed, anamu).

  The West Indian medical journal 20070101

• Band shape determination with robust estimator based on continuous wavelet transform.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20061001

• An unprecedented rearrangement in collision-induced mass spectrometric fragmentation of protonated benzylamines.

  Journal of mass spectrometry : JMS 20060901

• Diterpenoids and aromatic compounds from the three New Zealand liverworts Jamesoniella kirkii, Balantiopsis rosea, and Radula species.

  Chemical & pharmaceutical bulletin 20060601

• Simultaneous determination of phenols (bibenzyl, phenanthrene, and fluorenone) in Dendrobium species by high-performance liquid chromatography with diode array detection.

  Journal of chromatography. A 20060203

• Three new bibenzyl derivatives from Dendrobium nobile.

  Journal of Asian natural products research 20060101

• Structure-directing role of molecules containing benzyl rings in the synthesis of a large-pore aluminophosphate molecular sieve: an experimental and computational study.

  The journal of physical chemistry. B 20051124

• Ruthenium(III) chloride catalyzed efficient synthesis of unsymmetrical diorganyl selenides via cleavage of dibenzyl and diphenyl diselenides in the presence of zinc.

  The Journal of organic chemistry 20050902

• Dihydrophenanthrenes from Bletilla formosana.

  Chemical & pharmaceutical bulletin 20050901

• Phytotoxic activity of bibenzyl derivatives from the orchid Epidendrum rigidum.

  Journal of agricultural and food chemistry 20050810

• Bibenzyls and dihydroisocoumarins from white salsify (Tragopogon porrifolius subsp. porrifolius).

  Phytochemistry 20050701

• Photodecarbonylation of dibenzyl ketones and trapping of radical intermediates by copper(II) chloride in frozen aqueous solutions.

  The journal of physical chemistry. B 20050519

• Carbon-halogen bond activation mechanism by copper(I) complexes of (2-pyridyl)alkylamine ligands.

  Inorganic chemistry 20050124

• The role of aromatic radical cations and benzylic cations in the 2,4,6-triphenylpyrylium tetrafluoroborate photosensitized oxidation of ring-methoxylated benzyl alcohols in CH2Cl2 solution.

  The Journal of organic chemistry 20041210

• Inhibition of endothelial cell functions by novel potential cancer chemopreventive agents.

  Biochemical and biophysical research communications 20041203

• Corsifurans A-C, 2-arylbenzofurans of presumed stilbenoid origin from Corsinia coriandrina (Hepaticae).

  Phytochemistry 20041201

• Controlling photochemistry with distinct hydrophobic nanoenvironments.

  Journal of the American Chemical Society 20041110

• Novel biologically active bibenzyls from Bauhinia saccocalyx Pierre.

  Chemistry & biodiversity 20041101

• Metabolic fate of orally administered phyllodulcin in rats.

  Journal of natural products 20040901

• In vitro anti-proliferation/cytotoxic activity of sixty natural products on the human SH-SY5Y neuroblastoma cells with specific reference to dibenzyl trisulphide.

  The West Indian medical journal 20040901

• Hydrosilylation of dienes by yttrium hydrido complexes containing a linked amido-cyclopentadienyl ligand.

  Dalton transactions (Cambridge, England : 2003) 20040807

• Water-soluble dendrimers as photochemical reaction media: chemical behavior of singlet and triplet radical pairs inside dendritic reaction cavities.

  Journal of the American Chemical Society 20040728

• Conformational switching caused by biphenyl substitution at the Calpha position: ethyl 2-benzyl-2-(formylamino)-3-phenylpropionate and ethyl 3-(1,1'-biphenyl-4-yl)-2-(formylamino)-2-(4-phenylbenzyl)propionate.

  Acta crystallographica. Section C, Crystal structure communications 20040701

• Synthesis and antiproliferative activity of 2,6-diamino-9-benzyl-9-deazapurine and related compounds.

  Bioorganic & medicinal chemistry 20040615

• Selective n,n-dibenzylation of primary aliphatic amines with dibenzyl carbonate in the presence of phosphonium salts.

  The Journal of organic chemistry 20040528

• Diisothiocyanate derivatives as potent, insurmountable antagonists of P2Y6 nucleotide receptors.

  Biochemical pharmacology 20040501

• Spasmolytic effects, mode of action, and structure-activity relationships of stilbenoids from Nidema boothii.

  Journal of natural products 20040201

• Potential toxic effect on aquatic fauna by the dwarf shrub Empetrum hermaphroditum.

  Journal of chemical ecology 20040101

• Synthesis and fungicidal activity of novel 4,4'-bis(2' '-aryl-5' '-methyl/unsubstituted-4' '-oxo-thiazolidin-3' '-yl) bibenzyl.

  Journal of agricultural and food chemistry 20031119

• Some 1,2-diphenylethane derivatives as inhibitors of retinoic acid--metabolising enzymes.

  Journal of enzyme inhibition and medicinal chemistry 20031001

• Iron(III) chloride-catalyzed convenient one-pot synthesis of homoallyl benzyl ethers starting from aldehydes.

  Organic letters 20030821

• The molecular biology of knockdown resistance to pyrethroid insecticides.

  Insect biochemistry and molecular biology 20030601

• New bibenzyl cannabinoid from the New Zealand liverwort Radula marginata.

  Chemical & pharmaceutical bulletin 20021001

• Supramolecular effects on the dynamics of radicals in MFI zeolites: a direct EPR investigation.

  The Journal of organic chemistry 20020809

• Dibenzyl 2,2'-(ethane-1,2-diylidene)dihydrazinecarbodithioate bis(dimethylformamide) solvate.

  Acta crystallographica. Section C, Crystal structure communications 20020801

• Synthesis and self-association of syn-5,10,15-trialkylated truxenes.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20020702

• EPR investigation of persistent radicals produced from the photolysis of dibenzyl ketones adsorbed on ZSM-5 zeolites.

  The Journal of organic chemistry 20020419

• [A new bibenzyl derivative from Bletilla striata].

  Yao xue xue bao = Acta pharmaceutica Sinica 20020301

• Eremophilanolides and other constituents from the Argentine liverwort Frullania brasiliensis.

  Phytochemistry 20020101

• Hydrogen peroxide oxidation of mustard-model sulfides catalyzed by iron and manganese tetraarylporphyrines. Oxygen transfer to sulfides versus H(2)O(2) dismutation and catalyst breakdown.

  The Journal of organic chemistry 20011116

• Quinone methide phosphodiester alkylations under aqueous conditions.

  The Journal of organic chemistry 20011019

• Disassembly of microtubules and inhibition of neurite outgrowth, neuroblastoma cell proliferation, and MAP kinase tyrosine dephosphorylation by dibenzyl trisulphide.

  Biochimica et biophysica acta 20010822

• Antifungal polysulphides from Petiveria alliacea L.

  Phytochemistry 20010701

• [The sonochemical-degradation mechanism of toluene in aqueous solution].

  Huan jing ke xue= Huanjing kexue 20010501