103028-31-5 | 4-Bromo-8-methoxyquinoline

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$17.00	$12.00
5g	98%	in stock	$281.00	$197.00
10g	98%	in stock	$541.00	$379.00
25g	98%	in stock	$1,069.00	$748.00
100g	98%	in stock	$2,841.00	$1,989.00

Description

• Catalog Number: AB66958
• Chemical Name: 4-Bromo-8-methoxyquinoline
• CAS Number: 103028-31-5
• Molecular Formula: C10H8BrNO
• Molecular Weight: 238.0806
• MDL Number: MFCD08063209
• SMILES: COc1cccc2c1nccc2Br

Computed Properties

• Complexity: 176
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 2.5

Upstream Synthesis Route

The compound 4-Bromo-8-methoxyquinoline plays a crucial role in chemical synthesis as a versatile building block. Its unique structure and reactivity make it a valuable tool for the preparation of various organic compounds. 4-Bromo-8-methoxyquinoline is commonly used as a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. Its bromine and methoxy functionalities enable selective functional group transformations, allowing for the introduction of diverse chemical moieties during synthetic routes. This compound is particularly useful in the construction of complex heterocyclic frameworks due to its quinoline scaffold, which can participate in a range of chemical reactions such as nucleophilic aromatic substitution, metal-catalyzed cross-coupling reactions, and heterocycle synthesis. Overall, 4-Bromo-8-methoxyquinoline serves as a valuable building block in the arsenal of organic chemists for the efficient and strategic synthesis of novel molecules.

Literature

• 4-Bromo-8-methoxy-quinoline.

  Acta crystallographica. Section E, Structure reports online 20080601