1030832-39-3 | 2-(Bromomethyl)-5-fluorophenylboronic acid, pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
250mg	96%	in stock	$53.00	$37.00
1g	96%	in stock	$135.00	$95.00
5g	96%	in stock	$473.00	$331.00
10g	96%	in stock	$775.00	$543.00
25g	96%	in stock	$1,536.00	$1,075.00

Description

• Catalog Number: AD49833
• Chemical Name: 2-(Bromomethyl)-5-fluorophenylboronic acid, pinacol ester
• CAS Number: 1030832-39-3
• Molecular Formula: C13H17BBrFO2
• Molecular Weight: 314.9863
• MDL Number: MFCD18434453
• SMILES: BrCc1ccc(cc1B1OC(C(O1)(C)C)(C)C)F

Computed Properties

• Complexity: 295
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2

Upstream Synthesis Route

The compound 2-(2-(Bromomethyl)-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane plays a pivotal role in chemical synthesis as a versatile building block. Its unique structure, combining a bromomethyl group with a fluorophenyl moiety on a boron-containing scaffold, offers a range of possibilities for creating complex organic molecules.In organic synthesis, this compound is commonly used as a key intermediate in Suzuki coupling reactions. The bromomethyl functionality serves as an excellent leaving group, facilitating cross-coupling reactions with various organic halides or pseudohalides under mild conditions. This enables the efficient construction of biaryl compounds, which are prevalent in medicinal chemistry, materials science, and agrochemical research.Furthermore, the presence of the fluoro substituent provides additional reactivity options, allowing for further derivatization or selective transformations of the molecule. By judiciously designing synthetic routes around this boronic ester, chemists can access a wide array of functionalized aryl boronates, which are essential precursors for pharmaceuticals, agrochemicals, and advanced materials.Overall, the strategic incorporation of 2-(2-(Bromomethyl)-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane in chemical synthesis processes offers a valuable tool for constructing diverse molecular architectures with potential applications across various sectors of the chemical industry.