10316-00-4 | 4-Benzylmorpholine

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$14.00	$10.00
1g	97%	in stock	$25.00	$17.00
5g	97%	in stock	$34.00	$24.00
10g	97%	in stock	$68.00	$48.00

Description

• Catalog Number: AD80909
• Chemical Name: 4-Benzylmorpholine
• CAS Number: 10316-00-4
• Molecular Formula: C11H15NO
• Molecular Weight: 177.2429
• MDL Number: MFCD00090503
• SMILES: O1CCN(CC1)Cc1ccccc1
• NSC Number: 67985

Computed Properties

• Complexity: 137
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• XLogP3: 1.6

Upstream Synthesis Route

4-Benzylmorpholine, a versatile chemical compound widely utilized in chemical synthesis, serves as a valuable building block for various organic transformations. Its unique structure and reactivity make it a crucial component in the development of pharmaceuticals, agrochemicals, and materials.In chemical synthesis, 4-Benzylmorpholine is frequently employed as a key intermediate in the production of complex molecules. Its benzyl group provides a handle for further functionalization, allowing chemists to introduce specific structural motifs and tailor the properties of the final product. Additionally, the morpholine moiety confers desirable characteristics such as solubility and stability, making 4-Benzylmorpholine a favored option in the synthesis of bioactive compounds.Furthermore, 4-Benzylmorpholine's compatibility with a variety of reaction conditions enables its use in diverse synthetic methodologies, including cross-coupling reactions, hydrogenation, and oxidation processes. This versatility extends its utility across a wide range of scientific disciplines, offering researchers a versatile tool to access novel molecules with enhanced properties.Overall, the application of 4-Benzylmorpholine in chemical synthesis extends far beyond its simple structure, showcasing its significance in accelerating the discovery and development of innovative compounds with valuable applications.

Literature

• Identification, design and biological evaluation of heterocyclic quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).

  Journal of medicinal chemistry 20120308

• In vitro and in vivo evaluation of select kahalalide F analogs with antitumor and antifungal activities.

  Bioorganic & medicinal chemistry 20111115

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Bis[2-(morpholinometh-yl)phen-yl]phenyl-phosphane.

  Acta crystallographica. Section E, Structure reports online 20091201

• Di-μ-chlorido-bis-{[2-(morpholinometh-yl)phenyl-κC,N]palladium(II)}.

  Acta crystallographica. Section E, Structure reports online 20080801

• Structural basis for the high-affinity binding of pyrrolotriazine inhibitors of p38 MAP kinase.

  Acta crystallographica. Section D, Biological crystallography 20080701

• Identification of small molecule inhibitors of Pseudomonas aeruginosa exoenzyme S using a yeast phenotypic screen.

  PLoS genetics 20080201