103321-50-2 | Fmoc-l-alanyl chloride

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$73.00	$51.00
1g	95%	in stock	$169.00	$118.00
5g	95%	in stock	$549.00	$384.00
10g	95%	in stock	$1,007.00	$705.00
25g	95%	in stock	$2,002.00	$1,402.00

Description

• Catalog Number: AD80642
• Chemical Name: Fmoc-l-alanyl chloride
• CAS Number: 103321-50-2
• Molecular Formula: C18H16ClNO3
• Molecular Weight: 329.7775
• MDL Number: MFCD00235802
• SMILES: O=C(N[C@H](C(=O)Cl)C)OCC1c2ccccc2-c2c1cccc2

Computed Properties

• Complexity: 434
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 23
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 5
• XLogP3: 4

Upstream Synthesis Route

Fmoc-Ala-Cl, or Fmoc-protected alanine chloride, is a commonly used reagent in chemical synthesis, especially in the field of peptide synthesis. This compound serves as a key building block for the creation of peptides and proteins through solid-phase peptide synthesis (SPPS) methods. When utilized in peptide synthesis, Fmoc-Ala-Cl acts as a selective protecting group that masks the amine functionality of the alanine amino acid. This protection ensures that during the subsequent coupling reactions, only the desired amine group participates, leading to precise and controlled peptide bond formation. Furthermore, the Fmoc (9-fluorenylmethyloxycarbonyl) protecting group can be easily removed under mild basic conditions, allowing for the stepwise elongation of the peptide chain. This flexibility and compatibility with standard peptide synthesis protocols make Fmoc-Ala-Cl a valuable tool in the preparation of complex peptides with high purity and yield. Overall, Fmoc-Ala-Cl plays a crucial role in enabling the efficient and reliable synthesis of peptides, which are essential molecules with a wide range of biological and pharmaceutical applications.