103361-99-5 | 7-Fluoro-2H-1,4-benzoxazin-3(4H)-one

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$42.00	$29.00
1g	95%	in stock	$70.00	$49.00
5g	95%	in stock	$336.00	$235.00
10g	95%	in stock	$572.00	$400.00
25g	95%	in stock	$1,210.00	$847.00
100g	95%	in stock	$3,091.00	$2,164.00

Description

• Catalog Number: AD70048
• Chemical Name: 7-Fluoro-2H-1,4-benzoxazin-3(4H)-one
• CAS Number: 103361-99-5
• Molecular Formula: C8H6FNO2
• Molecular Weight: 167.1371
• MDL Number: MFCD07774200
• SMILES: O=C1COc2c(N1)ccc(c2)F

Computed Properties

• Complexity: 198
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• XLogP3: 1

Upstream Synthesis Route

7-Fluoro-2H-1,4-benzoxazin-3(4H)-one is a versatile compound widely used in chemical synthesis for the preparation of pharmaceuticals, agrochemicals, and advanced materials. This compound serves as a key building block in various synthetic pathways, owing to its unique structural properties and reactivity.In chemical synthesis, 7-Fluoro-2H-1,4-benzoxazin-3(4H)-one can act as a nucleophilic or electrophilic component, participating in a range of reactions such as nucleophilic substitution, Friedel-Crafts acylation, and cyclization reactions. Its fluorine substituent enhances the compound's reactivity and stability, making it a valuable tool in the creation of complex molecular structures.Furthermore, the presence of the benzoxazine ring in 7-Fluoro-2H-1,4-benzoxazin-3(4H)-one provides opportunities for diversification through functional group manipulation, enabling targeted modifications to tailor the compound for specific applications. Its ability to undergo diverse transformations makes it a versatile and indispensable intermediate in synthetic chemistry, facilitating the efficient construction of novel compounds with potential biological or material properties.

Literature

• New herbicide models from benzoxazinones: aromatic ring functionalization effects.

  Journal of agricultural and food chemistry 20061227