10338-57-5 | 4-Piperidinobenzaldehyde

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$19.00	$13.00
5g	95%	in stock	$47.00	$33.00
25g	95%	in stock	$177.00	$124.00
100g	95%	in stock	$538.00	$377.00

Description

• Catalog Number: AB50200
• Chemical Name: 4-Piperidinobenzaldehyde
• CAS Number: 10338-57-5
• Molecular Formula: C12H15NO
• Molecular Weight: 189.2536
• MDL Number: MFCD00778395
• SMILES: O=Cc1ccc(cc1)N1CCCCC1
• NSC Number: 156549

Computed Properties

• Complexity: 179
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• XLogP3: 2.9

Upstream Synthesis Route

4-(Piperidin-1-yl)benzaldehyde is a versatile compound commonly used in chemical synthesis for its unique properties and reactivity. In organic chemistry, this compound serves as a valuable building block in the synthesis of various pharmaceuticals, agrochemicals, and fine chemicals.One of the key applications of 4-(Piperidin-1-yl)benzaldehyde is its role as a starting material in the synthesis of heterocyclic compounds. By reacting with different nucleophiles or electrophiles, it can undergo a variety of transformations to generate complex structures with diverse functionalities. This compound is particularly useful in forming fused heterocycles, which are prevalent in many bioactive molecules.Furthermore, 4-(Piperidin-1-yl)benzaldehyde is often employed in the preparation of ligands for coordination chemistry or as a precursor for the synthesis of chiral compounds. Its ability to undergo selective functionalization reactions makes it a valuable tool for accessing stereochemically complex molecules with high enantiomeric purity.Overall, the versatility and reactivity of 4-(Piperidin-1-yl)benzaldehyde make it a valuable component in the toolbox of synthetic chemists for building structurally diverse and biologically active compounds.

Literature

• (E)-2-[4-(Piperidin-1-yl)benzyl-idene]-2,3-dihydro-1H-inden-1-one.

  Acta crystallographica. Section E, Structure reports online 20101101

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Synthesis, receptor potency, and selectivity of halogenated diphenylpiperidines as serotonin 5-HT2A ligands for PET or SPECT brain imaging.

  Journal of medicinal chemistry 20020523