103476-89-7 | Leupeptin hemisulfate

Packsize	Purity	Availability	Price	Discounted Price
1mg	97%	in stock	$22.00	$16.00
10mg	≥90%	in stock	$80.00	$56.00
25mg	≥90%	in stock	$146.00	$102.00
50mg	≥90%	in stock	$272.00	$190.00
100mg	Ultra Pure Grade	in stock	$444.00	$311.00

Description

• Catalog Number: AI67518
• Chemical Name: Leupeptin hemisulfate
• CAS Number: 103476-89-7
• Molecular Formula: C20H38N6O4
• Molecular Weight: 426.5535
• MDL Number: MFCD00198027
• SMILES: O=CC(NC(=O)C(NC(=O)C(NC(=O)C)CC(C)C)CC(C)C)CCCN=C(N)N

Computed Properties

• Complexity: 683
• Covalently-Bonded Unit Count: 3
• Defined Atom Stereocenter Count: 6
• Heavy Atom Count: 65
• Hydrogen Bond Acceptor Count: 14
• Hydrogen Bond Donor Count: 12
• Rotatable Bond Count: 28

Literature

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  Experimental biology and medicine (Maywood, N.J.) 20021001

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  Regulatory peptides 20020415

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  Platelets 20020201

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  Hearing research 20020201

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  Journal of molecular neuroscience : MN 20020101

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  Biological chemistry 20020101

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  Cellular and molecular biology (Noisy-le-Grand, France) 20020101

• Internalization and stepwise degradation of heparan sulfate proteoglycans in rat hepatocytes.

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  Muscle & nerve 20011201

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  Cell death and differentiation 20011201

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  Molecular reproduction and development 20010501

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  BioTechniques 20010401

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  Toxicology 20010307

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  Biochimica et biophysica acta 20010209

• Leupeptin-induced appearance of partial fragment of betaine homocysteine methyltransferase during autophagic maturation in rat hepatocytes.

  Journal of biochemistry 20010201

• Salivary histatin 5 is a potent competitive inhibitor of the cysteine proteinase clostripain.

  FEBS letters 20010126

• Role of calcium-dependent protease(s) in globulization of isolated rat lens cortical fiber cells.

  Investigative ophthalmology & visual science 20010101

• Lysosomal involvement in hepatocyte cytotoxicity induced by Cu(2+) but not Cd(2+).

  Free radical biology & medicine 20010101

• Suppression of gingival inflammation induced by Porphyromonas gingivalis in rats by leupeptin.

  Japanese journal of pharmacology 20010101

• Kinetic and structural properties of two isoforms of trypsin isolated from the viscera of Japanese anchovy, Engraulis japonicus.

  Journal of protein chemistry 20010101

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  BMC structural biology 20010101

• Coaggregation of Porphyromonas gingivalis and Prevotella intermedia.

  Microbiology and immunology 20010101

• Characterization of an important enzymatic component in collagenase that is essential for the effective digestion of the human and porcine pancreas.

  Cell transplantation 20010101

• Il-1-related cytokine responses of nonimmune skin cells subjected to CEES exposure with and without potential vesicant antagonists.

  In vitro & molecular toxicology 20000101

• Activation of Xenopus eggs by proteases: possible involvement of a sperm protease in fertilization.

  Developmental biology 19990401

• Efficacy of serine protease inhibitors against Cryptosporidium parvum infection in a bovine fallopian tube epithelial cell culture system.

  The Journal of parasitology 19960801

• Agonist-induced internalization of the substance P (NK1) receptor expressed in epithelial cells.

  The Biochemical journal 19941001

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  Neurochemistry international 19921201

• Significant effects of Z-Gln-Val-Val-OME, common sequences of thiol proteinase inhibitors on thiol proteinases.

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  FEBS letters 19850909

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  The Journal of general virology 19850201