10349-57-2 | Quinoline-6-carboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$8.00	$5.00
5g	95%	in stock	$13.00	$9.00
10g	95%	in stock	$20.00	$14.00

Description

• Catalog Number: AB45441
• Chemical Name: Quinoline-6-carboxylic acid
• CAS Number: 10349-57-2
• Molecular Formula: C10H7NO2
• Molecular Weight: 173.1681
• MDL Number: MFCD00047613
• SMILES: OC(=O)c1ccc2c(c1)cccn2

Computed Properties

• Complexity: 205
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 1.3

Upstream Synthesis Route

Quinoline-6-carboxylic acid plays a crucial role in chemical synthesis as a versatile building block. Its unique structure and functional groups make it a valuable intermediate in the production of various organic compounds. This compound is commonly used in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals.In pharmaceutical synthesis, quinoline-6-carboxylic acid serves as a key starting material for the preparation of quinoline-based drugs. Its ability to undergo various transformations allows for the introduction of specific functional groups that are essential for the biological activity of the final drug compound. Additionally, quinoline derivatives have shown promising anticancer, antimalarial, and antibacterial properties, making them important targets in drug discovery efforts.In the field of agrochemicals, quinoline-6-carboxylic acid is utilized in the synthesis of pesticides, herbicides, and fungicides. By incorporating this compound into the molecular structure of these agricultural chemicals, researchers can enhance their efficacy and selectivity, leading to improved crop protection and pest management solutions.Moreover, quinoline-6-carboxylic acid serves as a valuable building block in the development of specialty chemicals such as dyes, pigments, and materials. Its versatile reactivity allows for the creation of complex molecular architectures with tailored properties, enabling the customization of products for specific industrial applications.Overall, the application of quinoline-6-carboxylic acid in chemical synthesis demonstrates its importance as a versatile and indispensable component in the creation of diverse organic compounds with medicinal, agricultural, and industrial significance.

Literature

• Poly[(μ(3)-quinoline-6-carboxyl-ato-κ(3)N:O:O')silver(I)].

  Acta crystallographica. Section E, Structure reports online 20120601

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Regioselective oxidation of indole- and quinolinecarboxylic acids by cytochrome P450 CYP199A2.

  Applied microbiology and biotechnology 20100201

• Copper(I)-rhenate hybrids: syntheses, structures, and optical properties.

  Inorganic chemistry 20070219