1035270-39-3 | Azd4547

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$7.00	$5.00
5mg	98%	in stock	$14.00	$10.00
10mg	98%	in stock	$21.00	$15.00
250mg	98%	in stock	$168.00	$118.00

Description

• Catalog Number: AE11127
• Chemical Name: Azd4547
• CAS Number: 1035270-39-3
• Molecular Formula: C26H33N5O3
• Molecular Weight: 463.5719
• MDL Number: MFCD22580423
• SMILES: COc1cc(CCc2[nH]nc(c2)NC(=O)c2ccc(cc2)N2C[C@H](C)N[C@@H](C2)C)cc(c1)OC

Computed Properties

• Complexity: 622
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 2
• Heavy Atom Count: 34
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 8
• XLogP3: 3.9

Literature

• Design, synthesis and biological evaluation of novel FGFR inhibitors bearing an indazole scaffold.

  Organic & biomolecular chemistry 20150728

• Transforming fusions of FGFR and TACC genes in human glioblastoma.

  Science (New York, N.Y.) 20120907

• AZD4547: an orally bioavailable, potent, and selective inhibitor of the fibroblast growth factor receptor tyrosine kinase family.

  Cancer research 20120415