103628-48-4 | Sumatriptan succinate

Packsize	Purity	Availability	Price	Discounted Price
5mg	95%	in stock	$42.00	$29.00
1g	95%	in stock	$60.00	$42.00
5g	95%	in stock	$177.00	$124.00
25g	95%	in stock	$611.00	$428.00
100g	95%	in stock	$1,535.00	$1,074.00

Description

• Catalog Number: AB79262
• Chemical Name: Sumatriptan succinate
• CAS Number: 103628-48-4
• Molecular Formula: C18H27N3O6S
• Molecular Weight: 413.4885
• MDL Number: MFCD00902856
• SMILES: OC(=O)CCC(=O)O.CNS(=O)(=O)Cc1ccc2c(c1)c(CCN(C)C)c[nH]2
• NSC Number: 760362

Computed Properties

• Complexity: 498
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 28
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 9

Literature

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  The journal of headache and pain 20121101

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  Danish medical journal 20120701

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  The journal of headache and pain 20120301

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  Annals of neurology 20111101

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• Electrocatalytic determination of sumatriptan on the surface of carbon-paste electrode modified with a composite of cobalt/Schiff-base complex and carbon nanotube.

  Bioelectrochemistry (Amsterdam, Netherlands) 20110601

• Modulation of the postprandial acid and bile pockets at the gastro-oesophageal junction by drugs that affect gastric motility.

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• Elastic vesicles of sumatriptan succinate for transdermal administration: characterization and in vitro permeation studies.

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  Journal of cardiovascular pharmacology 20101101

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• Calcitonin gene-related peptide (CGRP) levels during glyceryl trinitrate (GTN)-induced headache in healthy volunteers.

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• Drug dependence associated with triptans and ergot derivatives: a case/non-case study.

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• Costs of hypothalamic stimulation in chronic drug-resistant cluster headache: preliminary data.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20090501

• Acute myocardial infarction with sumatriptan: a case report and review of the literature.

  Headache 20090501

• Nasal sumatriptan as adjunctive therapy for idiopathic trigeminal neuralgia: report of three cases.

  Headache 20090501

• Multimechanistic (sumatriptan-naproxen) early intervention for the acute treatment of migraine.

  Neurology 20090414

• Sumatriptan does not change calcitonin gene-related peptide in the cephalic and extracephalic circulation in healthy volunteers.

  The journal of headache and pain 20090401

• Evidence base for the medical treatments used in cluster headache.

  Current pain and headache reports 20090401

• Reporting adverse drug reactions.

  Southern medical journal 20090401

• An unusual case of colonic ischemia.

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• Evaluation of polymeric films for buccal drug delivery.

  Die Pharmazie 20090301

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  Headache 20090101

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  Headache 20090101

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  International journal of clinical practice 20081201

• Possible role of spleen-derived factors, vanilloid receptors and calcitonin gene-related peptide in diabetes induced hyperalgesia in mice.

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20081101

• Pain treatment and relief among patients with primary headache subtypes in the ED.

  The American journal of emergency medicine 20081101

• Profound reduction of somatic and visceral pain in mice by intrathecal administration of the anti-migraine drug, sumatriptan.

  Pain 20081031

• Sumatriptan does not affect arteriovenous oxygen differences in jugular and cubital veins in normal human subjects.

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• Difference in triptan effect in patients with migraine and early allodynia.

  Cephalalgia : an international journal of headache 20081001

• Investigation of the immunoreactivities of NOS enzymes and the effect of sumatriptan in adolescent rats using an experimental model of migraine.

  The journal of headache and pain 20081001

• Reversal of inflammatory and noninflammatory visceral pain by central or peripheral actions of sumatriptan.

  Gastroenterology 20081001

• New therapies may ease headache symptoms. A two-drug combo and two kinds of oxygen therapy show promise for relieving migraine and cluster headache pain.

  DukeMedicine healthnews 20081001

• Frovatriptan and data publication.

  Headache 20081001

• Subcutaneous sumatriptan relieved migraine-like headache in two adolescents with aseptic meningitis.

  Headache 20080901

• Production of ultrafine sumatriptan succinate particles for pulmonary delivery.

  Pharmaceutical research 20080901

• Mucoadhesive bilayered patches for administration of sumatriptan succinate.

  AAPS PharmSciTech 20080901

• Sumatriptan/naproxen sodium combination for the treatment of migraine.

  Expert review of neurotherapeutics 20080901

• Goshuyuto, a traditional Japanese medicine for migraine, inhibits platelet aggregation in guinea-pig whole blood.

  Journal of pharmacological sciences 20080901

• Nitroglycerin facilitates calcitonin gene-related peptide-induced behavior.

  Neuroreport 20080827

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  Neurology 20080708

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• Acute treatment and prevention of menstrually related migraine headache: evidence-based review.

  Neurology 20080422

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• [National ranking exam. N64. What could fall at the exam?].

  La Revue du praticien 20080315

• Recurrent headache due to MS plaque.

  Headache 20080301

• Migraine-like headache in intracranial haemorrhage is alleviated by sumatriptan and almotriptan.

  Cephalalgia : an international journal of headache 20080301

• Sumatriptan normalizes the migraine attack-related increase in brain serotonin synthesis.

  Neurology 20080205

• [Current diagnosis and treatment of migraine].

  Schmerz (Berlin, Germany) 20080201

• Predictors of migraine headache recurrence: a pooled analysis from the eletriptan database.

  Headache 20080201

• [Pathophysiology and treatment of trigeminal autonomic cephalalgias].

  Schmerz (Berlin, Germany) 20080201

• Activation of the 5-HT1B/D receptor reduces hindlimb neurogenic inflammation caused by sensory nerve stimulation and capsaicin.

  Pain 20080101

• Acute treatment of paediatric migraine: a meta-analysis of efficacy.

  Journal of paediatrics and child health 20080101

• Acute pathological laughter induced by sumatriptan.

  Cephalalgia : an international journal of headache 20080101

• 5-HT1B receptor subtype and aging in rat resistance vessels.

  Pharmacology 20080101

• Practice guideline for diagnosis and management of migraine headaches in children and adolescents: Part two.

  Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners 20080101

• Relevance of absorption rate and lag time to the onset of action in migraine.

  Clinical pharmacokinetics 20080101

• [Cerebrovascular serotonin antagonists and agonist among tropan derivatives].

  Eksperimental'naia i klinicheskaia farmakologiia 20080101

• Triptan drugs, natural killer cell cytotoxicity, and neutrophils pro-matrix metalloproteinase-9 secretion.

  Headache 20080101

• Sumatriptan inhibits synaptic transmission in the rat midbrain periaqueductal grey.

  Molecular pain 20080101

• Activation of the cortical pain network by soft tactile stimulation after injection of sumatriptan.

  Pain 20071215

• Sumatriptan nasal spray in the acute treatment of migraine in adolescents and children.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20071101

• Myocardial infarction after oral sumatriptan use in a woman with normal coronary arteries.

  The American journal of medicine 20071101

• A unique iontophoretic patch for optimal transdermal delivery of sumatriptan.

  Pharmaceutical research 20071001

• Parenteral vs. oral sumatriptan and naratriptan: plasma levels and efficacy in migraine. a comment.

  The journal of headache and pain 20071001

• Analysis of responses in migraine modelling using hidden Markov models.

  Statistics in medicine 20070930

• Combination of sumatriptan and naproxen for migraine.

  JAMA 20070919

• [Trigeminal autonomic cephalgias: diagnostic and therapeutic implications].

  MMW Fortschritte der Medizin 20070906

• Onion phases of PEG-8 distearate.

  Journal of pharmaceutical sciences 20070901

• Sumatriptan for prevention of acute mountain sickness: randomized clinical trial.

  Annals of neurology 20070901

• An evaporation-free solid-phase extraction method for rapid and accurate analysis of sumatriptan in human plasma by LC-MS/MS.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070901

• [Acute migraine. Sumatriptan-naproxen combination tablets work better than a single substance].

  Medizinische Monatsschrift fur Pharmazeuten 20070901

• Efficacy of dosing and re-dosing of two oral fixed combinations of indomethacin, prochlorperazine and caffeine compared with oral sumatriptan in the acute treatment of multiple migraine attacks: a double-blind, double-dummy, randomised, parallel group, multicentre study.

  International journal of clinical practice 20070801

• Sumatriptan fast-disintegrating/rapid-release tablets in the acute treatment of migraine.

  Expert review of neurotherapeutics 20070801

• Dark green blood in the operating theatre.

  Lancet (London, England) 20070609

• Efficacy and safety of 1,000 mg effervescent aspirin: individual patient data meta-analysis of three trials in migraine headache and migraine accompanying symptoms.

  Journal of neurology 20070601

• Characterization of the human basilar artery contractile response to 5-HT and triptans.

  Fundamental & clinical pharmacology 20070601

• Sorbitan ester organogels for transdermal delivery of sumatriptan.

  Drug development and industrial pharmacy 20070601

• [Bonus-malus regulations in the framework of the AVWG guideline-suitable migraine therapy are possible].

  MMW Fortschritte der Medizin 20070521

• In vitro and in vivo evaluation of the transdermal iontophoretic delivery of sumatriptan succinate.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070501

• Sumatriptan/Naproxen sodium for migraine: efficacy, health related quality of life, and satisfaction outcomes.

  Headache 20070501

• The phe-124-Cys and A-161T variants of the human 5-HT1B receptor gene are not major determinants of the clinical response to sumatriptan.

  Headache 20070501

• Diplotypes of the human serotonin 1B receptor promoter predict growth hormone responses to sumatriptan in abstinent alcohol-dependent men.

  Biological psychiatry 20070415

• Sumatriptan-naproxen for acute treatment of migraine: a randomized trial.

  JAMA 20070404

• Activation of 5-HT1B and 5-HT1D receptors in the rat nucleus tractus solitarius: opposing action on neurones that receive an excitatory vagal C-fibre afferent input.

  British journal of pharmacology 20070401

• Major therapeutic advances in the past 25 years.

  Headache 20070401

• Satisfaction with current migraine therapy: experience from 3 centers in US and Sweden.

  Headache 20070401

• Patient information regarding subcutaneous self-administration of sumatriptan (imitrex).

  Headache 20070401

• Benign or sinister? Distinguishing migraine from subarachnoid hemorrhage.

  Headache 20070301

• Sumatriptan 6 mg subcutaneous as an effective migraine treatment in patients with cutaneous allodynia who historically fail to respond to oral triptans.

  The journal of headache and pain 20070201

• Sumatriptan and corneal reflexes in headache-free migraine patients: a randomized and placebo-controlled crossover study.

  Cephalalgia : an international journal of headache 20070201

• Typical cluster headache caused by granulomatous pituitary involvement.

  Cephalalgia : an international journal of headache 20070201

• Clarification of developing and established clinical allodynia and pain-free outcomes.

  Headache 20070201

• Intranasal sumatriptan study with high placebo response in Taiwanese patients with migraine.

  Journal of the Chinese Medical Association : JCMA 20070201

• Sumatriptan provokes coronary artery spasm in patients with variant angina: possible involvement of serotonin 1B receptor.

  International journal of cardiology 20070108

• Sumatriptan for the treatment of undifferentiated primary headaches in the ED.

  The American journal of emergency medicine 20070101

• Fugue associated with migraine.

  Journal of neurology, neurosurgery, and psychiatry 20070101

• Actions of sumatriptan on myenteric neurones: relief from an old headache in the enteric nervous system?

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20070101

• Sumatriptan is an agonist at 5-HT receptors on myenteric neurones in the guinea-pig gastric antrum.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20070101

• Twelve-month tolerability and safety of sumatriptan-naproxen sodium for the treatment of acute migraine.

  Mayo Clinic proceedings 20070101

• Efficacy of sumatriptan tablets in migraineurs self-described or physician-diagnosed as having sinus headache: a randomized, double-blind, placebo-controlled study.

  Clinical therapeutics 20070101

• The effect of maternal ketanserin treatment on foetal 5-HT receptor function in umbilical cord artery of pre-eclamptic patients.

  Neonatology 20070101

• [Electroencephalographic changes in headaches under the influence of pharmaceuticals].

  Medicinski arhiv 20070101

• Over-the-counter triptans for migraine : what are the implications?

  CNS drugs 20070101

• Two double-blind, multicenter, randomized, placebo-controlled, single-dose studies of sumatriptan/naproxen sodium in the acute treatment of migraine: function, productivity, and satisfaction outcomes.

  MedGenMed : Medscape general medicine 20070101

• Hypothalamic activation in spontaneous migraine attacks.

  Headache 20070101

• Diagnosis of menstrual headache and an open-label study among those with previously undiagnosed menstrually related migraine to evaluate the efficacy of sumatriptan 100 mg.

  Clinical therapeutics 20070101

• [Efficacy of sumamigren at early and late stages of migraine attack].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20070101

• The specific treatment of migraine: a story about one triptan.

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20070101

• [Acute and chronic headaches].

  La Revue du praticien 20061215

• Paroxysmal neuralgic upper cervical pain attacks: the lower syndrome of cluster headache.

  Clinical neurology and neurosurgery 20061201

• Cortical serotonin7, 1D and 1F receptors: effects of schizophrenia, suicide and antipsychotic drug treatment.

  Schizophrenia research 20061201

• Eosinophilic myocarditis: case series and review of literature.

  The Canadian journal of cardiology 20061201

• Treatment with sumatriptan 50 mg in the mild phase of migraine attacks in patients with infrequent attacks: a randomised, double-blind, placebo-controlled study.

  The journal of headache and pain 20061201

• Acute hypothalamic stimulation and ongoing cluster headache attacks.

  Neurology 20061128

• [Self-medication of migraine and headache].

  MMW Fortschritte der Medizin 20061123

• Intravital microscopy on a closed cranial window in mice: a model to study trigeminovascular mechanisms involved in migraine.

  Cephalalgia : an international journal of headache 20061101

• A model-based approach to treatment comparison in acute migraine.

  British journal of clinical pharmacology 20061101

• Combination strategies for enhancing transdermal absorption of sumatriptan through skin.

  International journal of pharmaceutics 20061012

• Influence of delaying gastric emptying on meal-related symptoms in healthy subjects.

  Alimentary pharmacology & therapeutics 20061001

• EFNS guidelines on the treatment of cluster headache and other trigeminal-autonomic cephalalgias.

  European journal of neurology 20061001

• Sumatriptan alleviates pain in patients with trigeminal neuralgia.

  The Clinical journal of pain 20061001

• Intracranial hypotension following chiropractic spinal manipulation.

  Headache 20061001

• Efficacy and tolerability of sumatriptan injection for the treatment of morning migraine: two multicenter, prospective, randomized, double-blind, controlled studies in adults.

  Clinical therapeutics 20061001

• Migraine headaches: a historical prospective, a glimpse into the future, and migraine epidemiology.

  Disease-a-month : DM 20061001

• When cluster headache was called histaminic cephalalgia (Horton's headache).

  The journal of headache and pain 20060901

• Spontaneous splenic infarction associated with sumatriptan use.

  The journal of headache and pain 20060901

• Donitriptan, but not sumatriptan, inhibits capsaicin-induced canine external carotid vasodilatation via 5-HT1B rather than 5-HT1D receptors.

  British journal of pharmacology 20060901

• Migraine: emerging treatment options for preventive and acute attack therapy.

  Expert opinion on emerging drugs 20060901

• Cluster headache: clinical presentation, lifestyle features, and medical treatment.

  Headache 20060901

• Thermoreversible-mucoadhesive gel for nasal delivery of sumatriptan.

  AAPS PharmSciTech 20060901

• [Medication-overuse headache].

  MMW Fortschritte der Medizin 20060831

• 5-Hydroxytryptamine-induced contraction of human temporal arteries coexpressing 5-HT2A receptors and wild-type or variant (Phe124Cys) 5-HT1B receptors: increased contribution of 5-HT1B receptors to the total contractile amplitude in arteries from Phe124Cys heterozygous individuals.

  Pharmacogenetics and genomics 20060801

• Sumatriptan: update and review.

  Expert opinion on pharmacotherapy 20060801

• Prevalence of migraine and response to sumatriptan in patients self-reporting tension/stress headache.

  Current medical research and opinion 20060801

• The impact of different antimigraine compounds on platelet and erythrocyte aggregation.

  Cephalalgia : an international journal of headache 20060801

• Sumatriptan causes parallel decrease in plasma CGRP concentration and migraine headache during nitroglycerin-induced migraine attack.

  Cephalalgia : an international journal of headache 20060801

• Functional neuroimaging of primary headache disorders.

  Expert review of neurotherapeutics 20060801

• Bioadhesive monolayer film for the in vitro transdermal delivery of sumatriptan.

  Journal of pharmaceutical sciences 20060701

• Functional reactivity of 5-HT receptors in human umbilical cord and maternal subcutaneous fat arteries after normotensive or pre-eclamptic pregnancy.

  Journal of hypertension 20060701

• Acute effects of sumatriptan on aortic blood pressure, stiffness, and pressure waveform.

  Clinical pharmacology and therapeutics 20060701

• [Triptans and stroke].

  Lakartidningen 20060701

• The natural course of migraine attacks. A prospective analysis of untreated attacks compared with attacks treated with a triptan.

  Cephalalgia : an international journal of headache 20060601

• A clinical trial of trimethobenzamide/diphenhydramine versus sumatriptan for acute migraines.

  Headache 20060601

• Migraine headache in children.

  Clinical evidence 20060601

• Cutaneous allodynia and migraine: another view.

  Current pain and headache reports 20060601

• [Triptanes in the treatment of migraine. A review based on three Cochrane reviews].

  Ugeskrift for laeger 20060508

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Concomitant variations of gastric tone and duodenal motility in humans: results of a placebo-controlled study assessing octreotide and sumatriptan.

  Scandinavian journal of gastroenterology 20060501

• Cluster headache attack due to sildenafil intake.

  Cephalalgia : an international journal of headache 20060501

• [First generic triptan approved].

  MMW Fortschritte der Medizin 20060420

• Prediction of headache response in migraine treatment.

  Cephalalgia : an international journal of headache 20060401

• Does earlier headache response equate to earlier return to functioning in patients suffering from migraine?

  Cephalalgia : an international journal of headache 20060401

• Assessment of clinical, service, and cost outcomes of a conversion program of sumatriptan to rizatriptan ODT in primary care patients with migraine headaches.

  Journal of managed care pharmacy : JMCP 20060401

• Nitric oxide regulation of calcitonin gene-related peptide gene expression in rat trigeminal ganglia neurons.

  The European journal of neuroscience 20060401

• Subcutaneous sumatriptan for refractory trigeminal neuralgia.

  Headache 20060401

• Intranasal sumatriptan for prevention of post-ECT headaches.

  Headache 20060401

• Influence of sumatriptan on the autonomic system during migraine attacks.

  The journal of headache and pain 20060401

• A randomized, double-blind, placebo-controlled trial of the efficacy and tolerability of a 4-mg dose of subcutaneous sumatriptan for the treatment of acute migraine attacks in adults.

  Clinical therapeutics 20060401

• Effect of 5-HT1 agonist (sumatriptan) on anorectal function in irritable bowel syndrome patients.

  World journal of gastroenterology 20060314

• Intensive community pharmacy intervention had little impact on triptan consumption: a randomized controlled trial.

  Scandinavian journal of primary health care 20060301

• The risks of sumatriptan administration in patients with unrecognized subarachnoid haemorrhage (SAH).

  Cephalalgia : an international journal of headache 20060301

• Polytherapy in the preventive and acute treatment of migraine: fundamentals for changing the approach.

  Expert review of neurotherapeutics 20060301

• [Are children getting the right drugs?].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20060209

• Atrial fibrillation following oral sumatriptan administration.

  International journal of cardiology 20060208

• Infrequent or non-response to oral sumatriptan does not predict response to other triptans--review of four trials.

  Cephalalgia : an international journal of headache 20060201

• Subcutaneous sumatriptan provides symptomatic relief at any pain intensity or time during the migraine attack.

  Cephalalgia : an international journal of headache 20060201

• Sumatriptan nasal spray in adolescent migraineurs: a randomized, double-blind, placebo-controlled, acute study.

  Headache 20060201

• Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial--a comment.

  Headache 20060201

• A comment on acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial.

  Headache 20060201

• A case of sumatriptan-induced intestinal ischemia.

  Journal of gastroenterology 20060201

• Pain free efficacy of sumatriptan in the early treatment of migraine.

  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20060201

• Acute myocardial infarction after sumatriptan administration for cluster headache.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20060201

• Preliminary brain-targeting studies on intranasal mucoadhesive microemulsions of sumatriptan.

  AAPS PharmSciTech 20060120

• Effect of modulation of serotonergic, cholinergic, and nitrergic pathways on murine fundic size and compliance measured by ultrasonomicrometry.

  American journal of physiology. Gastrointestinal and liver physiology 20060101

• Increased expression of endothelial and neuronal nitric oxide synthase in dura and pia mater after air stress.

  Cephalalgia : an international journal of headache 20060101

• Salivary levels of CGRP and VIP in rhinosinusitis and migraine patients.

  Headache 20060101

• Oral sumatriptan for the acute treatment of probable migraine: first randomized, controlled study.

  Headache 20060101

• [Medical treatment of migraine attacks in the child].

  Revue de l'infirmiere 20060101

• Sumatriptan fast-disintegrating/rapid-release tablets.

  Drugs 20060101

• Sumatriptan fast-disintegrating/rapid-release tablets: viewpoints.

  Drugs 20060101

• [Pharmacotherapy: migraine and depression. Therapy with sumatripten and citalopram: perioperative anaesthesiological risk assessment].

  Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 20060101

• Practical strategy for detecting and relieving cluster headaches.

  The Journal of family practice 20051201

• Accessing a new medication in Germany: a novel approach to assess a health insurance-related barrier.

  Annals of epidemiology 20051101

• Donitriptan decreases jugular venous oxygen saturation in rats in the absence of cranial vasoconstriction: an overlooked mechanism of antimigraine action?

  The Journal of pharmacology and experimental therapeutics 20051101

• Effects of sumatriptan and eletriptan on diseased epicardial coronary arteries.

  European journal of clinical pharmacology 20051101

• The effect of early intervention with sumatriptan tablets on migraine-associated productivity loss.

  Journal of occupational and environmental medicine 20051101

• Early intervention in migraine with sumatriptan tablets 50 mg versus 100 mg: a pooled analysis of data from six clinical trials.

  Clinical therapeutics 20051101

• A trial of metoclopramide vs sumatriptan for the emergency department treatment of migraines.

  Neurology 20051025

• A trial of metoclopramide vs sumatriptan for the emergency department treatment of migraines.

  Neurology 20051025

• Validation of a rat behavioral avoidance model from a drug delivery perspective.

  International journal of pharmaceutics 20051013

• Iontophoretic transdermal delivery of sumatriptan: effect of current density and ionic strength.

  Journal of pharmaceutical sciences 20051001

• Over-the-counter triptans--making the switch.

  The Lancet. Neurology 20051001

• Uncertainty analysis in pharmacokinetics and pharmacodynamics: application to naratriptan.

  Pharmaceutical research 20051001

• Efficacy of almotriptan 12.5 mg in achieving migraine-related composite endpoints: a double-blind, randomized, placebo-controlled study in patients controlled study in patients with previous poor response to sumatriptan 50 mg.

  Current medical research and opinion 20051001

• Triptan-induced contractile (5-HT1B receptor) responses in human cerebral and coronary arteries: relationship to clinical effect.

  Clinical science (London, England : 1979) 20050901

• Effect of chemical enhancers on the in vitro percutaneous absorption of sumatriptan succinate.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20050901

• Therapeutic benefit of eletriptan compared to sumatriptan for the acute relief of migraine pain--results of a model-based meta-analysis that accounts for encapsulation.

  Cephalalgia : an international journal of headache 20050901

• Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial.

  Headache 20050901

• Sumatriptan and naproxen sodium for the acute treatment of migraine.

  Headache 20050901

• Treatment of cluster headache attacks with less than 6 mg subcutaneous sumatriptan.

  Headache 20050901

• Change in frequency pattern in cluster headache induced by subcutaneous sumatriptan.

  Headache 20050901

• Sumatriptan and zolmitriptan.

  Nursing times 20050901

• Pharmacokinetics of sumatriptan in non-respondent and in adverse drug reaction reporting migraine patients.

  The journal of headache and pain 20050901

• Biochemical evidence of the placebo effect during the treatment of menstrual migraines.

  Journal of clinical psychopharmacology 20050801

• Open label study of intranasal sumatriptan (Imigran) for footballer's headache.

  British journal of sports medicine 20050801

• Symptomatic treatment of migraine in children: a systematic review of medication trials.

  Pediatrics 20050801

• [Serotonin syndrome as a result of concomitant use of paroxetine and sumatriptan].

  Nederlands tijdschrift voor geneeskunde 20050716

• Multiple attack study on the available triptans in Italy versus placebo.

  European journal of neurology 20050701

• [Positron emission tomographic studies of migraine].

  Revue neurologique 20050701

• The treatment of acute migraine.

  Revue neurologique 20050701

• [Treatment of cluster headache].

  Revue neurologique 20050701

• Pharmacologic treatment of migraine. Comparison of guidelines.

  Canadian family physician Medecin de famille canadien 20050610

• A group sequential adaptive treatment assignment design for proof of concept and dose selection in headache trials.

  Contemporary clinical trials 20050601

• Resolution of concentration-response differences in onset of effect between subcutaneous and oral sumatriptan.

  Headache 20050601

• The treatment of pediatric migraine.

  Pediatric annals 20050601

• Acute treatment of pediatric headache in the emergency department and inpatient settings.

  Pediatric annals 20050601

• Sumatriptan: a potent drug for management of corneal lesion pain.

  Journal of cataract and refractive surgery 20050601

• Pharmacokinetic opportunities for combination therapy in migraine.

  Neurology 20050524

• [Therapy of severe migraine attacks: practical tips].

  MMW Fortschritte der Medizin 20050517

• Anxiogenic effects of Sumatriptan in panic disorder: a double-blind, placebo-controlled study.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20050501

• Triptans induce vasoconstriction of human arteries and veins from the thoracic wall.

  Journal of cardiovascular pharmacology 20050501

• Where do triptans act in the treatment of migraine?

  Pain 20050501

• Anti-migraine action of triptans is preceded by transient aggravation of headache caused by activation of meningeal nociceptors.

  Pain 20050501

• Nasal drug delivery of sumatriptan succinate.

  Die Pharmazie 20050501

• The headache of SAH responds to sumatriptan.

  Headache 20050501

• The perils of misinterpreting a treatment response.

  Headache 20050501

• [Serotonin syndrome as a result of concomitant use of paroxetine and sumatriptan].

  Nederlands tijdschrift voor geneeskunde 20050416

• Pilot study evaluating preference for 3-mg versus 6-mg subcutaneous sumatriptan.

  Headache 20050401

• Migraine treated with acyclovir.

  Headache 20050401

• Nasal sumatriptan: new dosage. For adolescents with migraine: too little benefit.

  Prescrire international 20050401

• Acute migraine attack, angina-like chest pain with documented ST-segment elevation and slow coronary flow.

  Acta cardiologica 20050401

• Two replicate randomized, double-blind, placebo-controlled trials of the time to onset of pain relief in the acute treatment of migraine with a fast-disintegrating/rapid-release formulation of sumatriptan tablets.

  Clinical therapeutics 20050401

• Managing migraine headaches experienced by patients who self-report with menstrually related migraine: a prospective, placebo-controlled study with oral sumatriptan.

  The journal of headache and pain 20050401

• Cluster-like headache after surgical crystalline removal and intraocular lens implant: a case report.

  The journal of headache and pain 20050401

• Non-human primate SPECT model for determining cerebral perfusion effects of cerebrovasoactive drugs acting via multiple modes of pharmacological action.

  Journal of the neurological sciences 20050315

• High-performance liquid chromatographic determination of sumatriptan after in vitro transdermal diffusion studies.

  Journal of pharmaceutical and biomedical analysis 20050309

• Sumatriptan causes parallel decrease in plasma calcitonin gene-related peptide (CGRP) concentration and migraine headache during nitroglycerin induced migraine attack.

  Cephalalgia : an international journal of headache 20050301

• [Pharmacologic treatment of acute migraine attack in children].

  Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20050301

• Cluster headache: diagnosis and treatment.

  Current neurology and neuroscience reports 20050301

• Evaluating the triptans.

  The American journal of medicine 20050301

• [3H]LY334370, a novel radioligand for the 5-HT1F receptor. II. Autoradiographic localization in rat, guinea pig, monkey and human brain.

  Naunyn-Schmiedeberg's archives of pharmacology 20050301

• A trial of metoclopramide vs sumatriptan for the emergency department treatment of migraines.

  Neurology 20050208

• Evidence for serotonin influencing the thalamic infiltration of mast cells in rat.

  Journal of neuroimmunology 20050201

• Patient preference for eletriptan 80 mg versus subcutaneous sumatriptan 6 mg: results of a crossover study in patients who have recently used subcutaneous sumatriptan.

  European journal of neurology 20050201

• [Therapeutic management of migraines in children].

  Soins. Pediatrie, puericulture 20050201

• Chronic cluster headache: a review.

  The journal of headache and pain 20050201

• Evaluation of the anti-emetic potential of anti-migraine drugs to prevent resiniferatoxin-induced emesis in Suncus murinus (house musk shrew).

  European journal of pharmacology 20050131

• [ST-segment elevation myocardial infarction following treatment with sumatriptan].

  Ugeskrift for laeger 20050103

• In vivo disintegration profiles of encapsulated and nonencapsulated sumatriptan: gamma scintigraphy in healthy volunteers.

  Journal of clinical pharmacology 20050101

• Correlation between lipophilicity and triptan outcomes.

  Headache 20050101

• Neuroendocrine challenge with a 5-HT(1D) receptor agonist differentiates between two subtypes of bipolar disorder according to polarity of onset.

  Journal of psychopharmacology (Oxford, England) 20050101

• Speed of onset, efficacy and tolerability of zolmitriptan nasal spray in the acute treatment of migraine: a randomised, double-blind, placebo-controlled study.

  CNS drugs 20050101

• Triptans and the incidence of epithelial defects during laser in situ keratomileusis.

  Journal of refractive surgery (Thorofare, N.J. : 1995) 20050101

• [Sumatriptan nasal spray for the treatment of cluster headache].

  No to shinkei = Brain and nerve 20050101

• Intranasal sumatriptan: in adolescents with migraine.

  CNS drugs 20050101

• Oral serotonin receptor agonists: a review of their cost effectiveness in migraine.

  PharmacoEconomics 20050101

• Almotriptan in migraine patients who respond poorly to oral sumatriptan: a double-blind, randomized trial.

  European neurology 20050101

• Cost-effectiveness analysis of rizatriptan and sumatriptan versus Cafergot in the acute treatment of migraine.

  CNS drugs 20050101

• Terminating migraine with allodynia and ongoing central sensitization using parenteral administration of COX1/COX2 inhibitors.

  Headache 20050101

• Almotriptan in migraine patients who respond poorly to oral sumatriptan: a double-blind, randomized trial.

  Headache 20050101

• Pharmacological challenge with a serotonin 1D agonist in alcohol dependence.

  BMC psychiatry 20050101

• A case of myocardial infarction with sumatriptan use.

  Pediatric cardiology 20050101

• The role of gastric accommodation in the pathophysiology of functional dyspepsia.

  European review for medical and pharmacological sciences 20050101

• [Particular features of the impact of certain vegetotropic drugs on the excitability of cholinergic structures, contractile myocardial function and electromotive stomach activity].

  Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20050101

• Cerebral vasospasm from sumatriptan.

  Neurology 20041214

• Hippocampal 5-hydroxytryptamine receptors: abnormalities in postmortem brain from schizophrenic subjects.

  Schizophrenia research 20041201

• Sumatriptan (5-HT1B/1D-agonist) causes a transient allodynia.

  Cephalalgia : an international journal of headache 20041201

• Effects of a fast disintegrating/rapid release oral formulation of sumatriptan on functional ability in patients with migraine.

  Current medical research and opinion 20041201

• Early treatment of a migraine attack while pain is still mild increases the efficacy of sumatriptan.

  Cephalalgia : an international journal of headache 20041101

• Placebo-controlled comparison of effervescent acetylsalicylic acid, sumatriptan and ibuprofen in the treatment of migraine attacks.

  Cephalalgia : an international journal of headache 20041101

• Diagnosis and management of migraine headaches.

  Southern medical journal 20041101

• [Therapeutic recommendations for migraine].

  Soins; la revue de reference infirmiere 20041101

• [Mechanism based prevention and treatment of migraine].

  Rinsho shinkeigaku = Clinical neurology 20041101

• Treatment of migraine headaches with sumatriptan in pregnancy.

  The Annals of pharmacotherapy 20041001

• Role of tension receptors in dyspeptic patients with hypersensitivity to gastric distention.

  Gastroenterology 20041001

• Indomethacin, alone and combined with prochlorperazine and caffeine, but not sumatriptan, abolishes peripheral and central sensitization in in vivo models of migraine.

  The journal of pain : official journal of the American Pain Society 20041001

• Acute drug treatment of migraine attack.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20041001

• Cluster headache: symptomatic treatment.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20041001

• Update on menstrual migraine: from clinical aspects to therapeutical strategies.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20041001

• Efficacy and tolerability of sumatriptan tablets administered during the mild-pain phase of menstrually associated migraine.

  International journal of clinical practice 20041001

• In vitro characterization of AR-A000002, a novel 5-hydroxytryptamine(1B) autoreceptor antagonist.

  European journal of pharmacology 20040919

• [Treatment and prophylaxis of an acute migraine attack].

  MMW Fortschritte der Medizin 20040902

• Effects of sumatriptan on capsaicin-induced carotid haemodynamic changes and CGRP release in anaesthetized pigs.

  Cephalalgia : an international journal of headache 20040901

• Effects of sumatriptan on rat medullary dorsal horn neurons.

  Pain 20040901

• Treatment of primary headache in the emergency department.

  Headache 20040901

• Revised estimates for probability of successful outcome of pregnancy after sumatriptan exposure.

  Headache 20040901

• [Triptans in migraine: a comparative review of pharmacology, pharmacokinetics].

  No to shinkei = Brain and nerve 20040901

• [Triptans in migraine: from clinical view].

  No to shinkei = Brain and nerve 20040901

• [Meta-analysis of triptan treatment in migraine].

  No to shinkei = Brain and nerve 20040901

• [Side effects of triptans].

  No to shinkei = Brain and nerve 20040901

• Effect of sumatriptan in different models of pain in rats.

  European journal of pharmacology 20040823

• Predicting the response to sumatriptan: the Sumatriptan Naratriptan Aggregate Patient Database.

  Neurology 20040810

• Triptan therapy impacts health and productivity.

  Journal of occupational and environmental medicine 20040801

• Switching patients with migraine from sumatriptan to other triptans increases primary care costs.

  International journal of clinical practice 20040801

• Serotoninergic nervous system in intact heart and abdominal organs.

  Bulletin of experimental biology and medicine 20040801

• High performance liquid chromatographic method for the determination of sumatriptan with fluorescence detection in human plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040705

• Involvement of 5-HT1B receptors in triptan-induced contractile responses in guinea-pig isolated iliac artery.

  Naunyn-Schmiedeberg's archives of pharmacology 20040701

• Bilateral cleft lip and palate, hypertelorism and hypoplastic toes.

  Clinical dysmorphology 20040701

• Cardiovascular safety of triptans.

  Cephalalgia : an international journal of headache 20040701

• Effect of high-dose intravenous eletriptan on coronary artery diameter.

  Cephalalgia : an international journal of headache 20040701

• Comparison of rizatriptan 5 mg and 10 mg tablets and sumatriptan 25 mg and 50 mg tablets.

  Cephalalgia : an international journal of headache 20040701

• The sumatriptan/naratriptan aggregated patient (SNAP) database: aggregation, validation and application.

  Cephalalgia : an international journal of headache 20040701

• Frovatriptan succinate, a 5-HT1B/1D receptor agonist for migraine.

  International journal of clinical practice 20040701

• The anti-migraine agent sumatriptan induces a calcium-dependent discharge in meningeal sensory neurons.

  Neuroreport 20040628

• Headaches that could spell trouble.

  Consumer reports 20040601

• Triptans and CNS side-effects: pharmacokinetic and metabolic mechanisms.

  Cephalalgia : an international journal of headache 20040601

• Nitroglycerin-induced nNOS increase in rat trigeminal nucleus caudalis is inhibited by systemic administration of lysine acetylsalicylate but not of sumatriptan.

  Cephalalgia : an international journal of headache 20040601

• Thyrotoxicosis, sumatriptan and coronary artery spasm.

  Journal of the Royal Society of Medicine 20040601

• Pharmacokinetic profile of a new form of sumatriptan tablets in healthy volunteers.

  Current medical research and opinion 20040601

• Migraine headache.

  Clinical evidence 20040601

• [Drug exposure during pregnancy: a differentiated approach].

  Praxis 20040526

• Elevated levels of circulating trace amines in primary headaches.

  Neurology 20040525

• Influence of 5-HT1 receptor agonists on feline stomach relaxation.

  European journal of pharmacology 20040525

• 5-Hydroxytryptamine1B receptor-mediated contraction of rabbit saphenous vein and basilar artery: role of vascular endothelium.

  The Journal of pharmacology and experimental therapeutics 20040501

• The disparity in access to new medication by type of health insurance: lessons from Germany.

  Medical care 20040501

• Double-blind clinical trials of oral triptans vs other classes of acute migraine medication - a review.

  Cephalalgia : an international journal of headache 20040501

• Effects of chronic sumatriptan and zolmitriptan treatment on 5-HT receptor expression and function in rats.

  Cephalalgia : an international journal of headache 20040501

• Metoclopramide and sumatriptan.

  Headache 20040501

• Inter-digestive and post-prandial antro-pyloro-duodenal motor activity in humans: effect of 5-hydroxytryptamine 1 receptor agonism.

  Alimentary pharmacology & therapeutics 20040401

• Pharmacokinetics of sumatriptan nasal spray in children.

  Journal of clinical pharmacology 20040401

• Effective treatment of migraine. Terminating acute attacks, reducing their frequency.

  Postgraduate medicine 20040401

• Managing migraine in children.

  Drug and therapeutics bulletin 20040401

• Almotriptan improves response rates when treatment is within 1 hour of migraine onset.

  Headache 20040401

• Nasal sumatriptan is effective in treatment of migraine attacks in children: A randomized trial.

  Neurology 20040323

• Effects of neuropeptides on the sumatriptan-disturbed circulation in the optic nerve head of rabbits.

  Pharmacology 20040301

• Diagnostic delays and mis-management in cluster headache.

  Acta neurologica Scandinavica 20040301

• Use and misuse of triptans in France: data from the GRIM2000 population survey.

  Cephalalgia : an international journal of headache 20040301

• Revised estimates for probability of successful outcome of pregnancy after sumatriptan exposure.

  Headache 20040301

• Patients with migraine prefer zolmitriptan orally disintegrating tablet to sumatriptan conventional oral tablet.

  International journal of clinical practice 20040301

• Quantifying delay in access to new medical treatment: an application of risk advancement period methodology.

  Epidemiology (Cambridge, Mass.) 20040301

• Sumatriptan: a decade of use and experience in the treatment of migraine.

  Expert review of neurotherapeutics 20040301

• Triptans in migraine: the risks of stroke, cardiovascular disease, and death in practice.

  Neurology 20040224

• [Use of triptanes according to indications. Risk of infarct is not increased].

  MMW Fortschritte der Medizin 20040212

• [Recent progress in therapy for migraine headache].

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20040210

• Further characterization of the 5-HT1 receptors mediating cardiac sympatho-inhibition in pithed rats: pharmacological correlation with the 5-HT1B and 5-HT1D subtypes.

  Naunyn-Schmiedeberg's archives of pharmacology 20040201

• The 40-mg dose of eletriptan: comparative efficacy and tolerability versus sumatriptan 100 mg.

  European journal of neurology 20040201

• Onset of effect of 5-HT1B/1D agonists: a model with pharmacokinetic validation.

  Headache 20040201

• Relationship between chronic tension-type headache, cranial hemodynamics, and cerebrospinal pressure: study involving provocation with sumatriptan.

  Headache 20040201

• Serotonin syndrome and the use of SSRIs.

  Journal of psychosocial nursing and mental health services 20040201

• Naratriptan for the treatment of acute migraine: meta-analysis of randomised controlled trials.

  Pharmacoepidemiology and drug safety 20040201

• Efficacy and tolerability of sumatriptan tablets in a fast-disintegrating, rapid-release formulation for the acute treatment of migraine: results of a multicenter, randomized, placebo-controlled study.

  Clinical therapeutics 20040201

• [Postpartum cerebral angiopathy--a case report the vasculopathy associated with co-administration of two vasoconstrictives, methylergometrine maleate and sumatriptan].

  Rinsho shinkeigaku = Clinical neurology 20040201

• Involvement of nitric oxide in fading of 5-hydroxytryptamine-induced vasocontraction in rat isolated vena portae smooth muscle.

  Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20040123

• Effects of acute or chronic administration of anti-migraine drugs sumatriptan and zolmitriptan on serotonin synthesis in the rat brain.

  Cephalalgia : an international journal of headache 20040101

• CNS effects of sumatriptan and rizatriptan.

  Cephalalgia : an international journal of headache 20040101

• Defeating migraine pain with triptans: a race against the development of cutaneous allodynia.

  Annals of neurology 20040101

• Analgesic triptan action in an animal model of intracranial pain: a race against the development of central sensitization.

  Annals of neurology 20040101

• Triptans and gastric accommodation: pharmacological and therapeutic aspects.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20040101

• Triptan use preceding life-threatening arrhythmias in charcot-marie-tooth: a case report and review of the literature.

  Clinical neuropharmacology 20040101

• Subcutaneous sumatriptan induces changes in frequency pattern in cluster headache patients.

  Headache 20040101

• Determining triptan preference for the individual patient.

  Headache 20040101

• A comparison of the cost-effectiveness of almotriptan and sumatriptan in the treatment of acute migraine using a composite efficacy/tolerability end point.

  Journal of managed care pharmacy : JMCP 20040101

• Efficacy of 1,000 mg effervescent acetylsalicylic acid and sumatriptan in treating associated migraine symptoms.

  European neurology 20040101

• Intranasal medications for the treatment of migraine and cluster headache.

  CNS drugs 20040101

• Cluster headache: the history of the Cluster Club and a review of recent clinical research.

  Functional neurology 20040101

• Coronary vasospasm and myocardial infarction induced by oral sumatriptan.

  Clinical neuropharmacology 20040101

• Pharmacokinetic interactions of topiramate.

  Clinical pharmacokinetics 20040101

• Oral sumatriptan-induced myocardial infarction.

  Journal of toxicology. Clinical toxicology 20040101

• Serotonergic dissection of obsessive compulsive symptoms: a challenge study with m-chlorophenylpiperazine and sumatriptan.

  Neuropsychobiology 20040101

• Long-term tolerability of sumatriptan nasal spray in adolescent patients with migraine.

  Headache 20040101

• Serotonin-1D hypothesis of obsessive-compulsive disorder: an update.

  The Journal of clinical psychiatry 20040101

• The responsiveness of headache impact scales scored using 'classical' and 'modern' psychometric methods: a re-analysis of three clinical trials.

  Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 20031201

• Prophylactic treatment of episodic cluster headache with intravenous bolus of methylprednisolone.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20031201

• Migraine headache.

  Clinical evidence 20031201

• Incidence and determinants of antidepressant drug use in migraine patients.

  International clinical psychopharmacology 20031101

• Hemicrania continua with contralateral episodic cluster headache: a case report.

  Cephalalgia : an international journal of headache 20031101

• A delayed class of BOLD waveforms associated with spreading depression in the feline cerebral cortex can be detected and characterised using independent component analysis (ICA).

  Magnetic resonance imaging 20031101

• Triptans for treatment of acute pediatric migraine: a systematic literature review.

  Pediatric neurology 20031101

• Parental satisfaction with sumatriptan nasal spray in childhood migraine.

  Journal of child neurology 20031101

• [Pitfall in migraine treatment].

  Rinsho shinkeigaku = Clinical neurology 20031101

• Clinical applications of new therapeutic deliveries in migraine.

  Neurology 20031028

• Investigation of the effects of naratriptan, rizatriptan, and sumatriptan on jugular venous oxygen saturation in anesthetized pigs: implications for their mechanism of acute antimigraine action.

  The Journal of pharmacology and experimental therapeutics 20031001

• Activation of pain by sumatriptan.

  Headache 20031001

• Pain-free results with sumatriptan taken at the first sign of migraine pain: 2 randomized, double-blind, placebo-controlled studies.

  Mayo Clinic proceedings 20031001

• Pain-free efficacy after treatment with sumatriptan in the mild pain phase of menstrually associated migraine.

  Obstetrics and gynecology 20031001

• A fluorescence-based method to assess plasma protein extravasation in rat dura mater using confocal laser scanning microscopy.

  Brain research. Brain research protocols 20031001

• Assessment of meal induced gastric accommodation by a satiety drinking test in health and in severe functional dyspepsia.

  Gut 20030901

• Efficacy of a fixed combination of indomethacin, prochlorperazine, and caffeine versus sumatriptan in acute treatment of multiple migraine attacks: a multicenter, randomized, crossover trial.

  Headache 20030901

• Unilateral time-delayed encapsulation does not make for a fair race.

  Headache 20030901

• Patients with migraine prefer zolmitriptan orally disintegrating tablet to sumatriptan conventional oral tablet.

  International journal of clinical practice 20030901

• Encapsulated sumatriptan is not bioequivalent to commercial sumatriptan.

  Headache 20030901

• Musing on Mathew et al.

  Headache 20030901

• Response to sumatriptan in headache of MELAS syndrome.

  Neurology 20030826

• Stability-indicating methods for the determination of sumatriptan succinate.

  Journal of pharmaceutical and biomedical analysis 20030821

• [Strong and sustained-acting triptan. Therewith migraine does not return soon].

  MMW Fortschritte der Medizin 20030807

• Role of 5-HT1B/D receptors in canine gastric accommodation: effect of sumatriptan and 5-HT1B/D receptor antagonists.

  American journal of physiology. Gastrointestinal and liver physiology 20030701

• Eletriptan for the treatment of migraine in patients with previous poor response or tolerance to oral sumatriptan.

  Cephalalgia : an international journal of headache 20030701

• Eletriptan metabolism by human hepatic CYP450 enzymes and transport by human P-glycoprotein.

  Drug metabolism and disposition: the biological fate of chemicals 20030701

• Pharmacokinetics of sumatriptan nasal spray in adolescents.

  Journal of clinical pharmacology 20030701

• Abnormal 5-HT1D receptor function in cluster headache: a neuroendocrine study with sumatriptan.

  Cephalalgia : an international journal of headache 20030601

• Studies on serotonergic markers in the human hippocampus: changes in subjects with bipolar disorder.

  Journal of affective disorders 20030601

• The truth about frovatriptan.

  Headache 20030601

• The link between glutamate and migraine.

  CNS spectrums 20030601

• [Improved pharmacokinetics. Fast tryptan with sustained response].

  MMW Fortschritte der Medizin 20030526

• [Highly selective beginning. Associated symptoms and side effects in retrospect].

  MMW Fortschritte der Medizin 20030526

• Conscious expectation and unconscious conditioning in analgesic, motor, and hormonal placebo/nocebo responses.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030515

• Cutaneous venous dysfunction studied in vivo in the LPS-treated rabbit: implication of NO in saphenous vein hyporeactivity.

  Naunyn-Schmiedeberg's archives of pharmacology 20030501

• A prospective double-blind study of nasal sumatriptan versus IV ketorolac in migraine.

  The American journal of emergency medicine 20030501

• Eletriptan vs sumatriptan: a double-blind, placebo-controlled, multiple migraine attack study.

  Neurology 20030408

• Topical agents in the treatment of cluster headache.

  Current pain and headache reports 20030401

• Efficacy of sumatriptan nasal spray in recurrent migrainous headache: an open prospective study.

  Headache 20030401

• Sumatriptan in migraine with unilateral cranial autonomic symptoms: an open study.

  Headache 20030401

• [Triptans overuse headache].

  Revista de neurologia 20030401

• Effects of in vivo treatment with interleukins 1beta and 6 on rat mesenteric vascular bed reactivity.

  Autonomic & autacoid pharmacology 20030401

• Cluster-like headache time-locked to the menstrual cycle.

  Neurology 20030325

• Migraine preventive medication reduces resource utilization.

  Headache 20030301

• Comparative efficacy of eletriptan 40 mg versus sumatriptan 100 mg.

  Headache 20030301

• Effect of autogenic training on drug consumption in patients with primary headache: an 8-month follow-up study.

  Headache 20030301

• Migraine: pathophysiology, pharmacology, treatment and future trends.

  Current vascular pharmacology 20030301

• Intranasal sumatriptan in cluster headache: randomized placebo-controlled double-blind study.

  Neurology 20030225

• Amplification of sumatriptan-induced contraction in rabbit saphenous vein but not in basilar artery.

  American journal of physiology. Heart and circulatory physiology 20030201

• Ergotamine and dihydroergotamine: a review.

  Current pain and headache reports 20030201

• Acupuncture versus placebo versus sumatriptan for early treatment of migraine attacks: a randomized controlled trial.

  Journal of internal medicine 20030201

• Pharmacologic characterization of contractile serotonergic receptors in human isolated mesenteric artery.

  Journal of cardiovascular pharmacology 20030201

• Single use of sumatriptan: a patient interview study.

  Headache 20030201

• Stimulation of the calcitonin gene-related peptide enhancer by mitogen-activated protein kinases and repression by an antimigraine drug in trigeminal ganglia neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030201

• Effect of the 5-HT1 agonist sumatriptan on oesophageal motor pattern in patients with ineffective oesophageal motility.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20030201

• Safety of sumatriptan in pregnancy: a review of the data so far.

  CNS drugs 20030101

• Tolerability of the triptans: clinical implications.

  Drug safety 20030101

• Validation and application of a high-performance liquid chromatography/tandem mass spectrometry assay for sumatriptan in human plasma.

  Biomedical chromatography : BMC 20030101

• An open-label study to assess changes in efficacy and satisfaction with migraine care when patients have access to multiple sumatriptan succinate formulations.

  Clinical therapeutics 20030101

• Expression of serotonin receptors in mouse oocytes and preimplantation embryos.

  Physiological research 20030101

• The triptan formulations : how to match patients and products.

  CNS drugs 20030101

• Cost-effectiveness of migraine treatment: a commentary.

  Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20030101

• A cost-effectiveness analysis of eletriptan 40 and 80 mg versus sumatriptan 50 and 100 mg in the acute treatment of migraine.

  Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20030101

• Migraine medication attributes important for patient compliance: concerns about side effects may delay treatment.

  Headache 20030101

• Misdiagnosis of migraine.

  Headache 20030101

• The use of sumatriptan in the treatment of obsessive-compulsive disorder in an adolescent.

  Journal of child and adolescent psychopharmacology 20030101

• Sumatriptan plus metoclopramide in triptan-nonresponsive migraineurs.

  Headache 20030101

• Management of trigeminal autonomic cephalgias and hemicrania continua.

  Drugs 20030101

• Oral sumatriptan for acute migraine.

  The Cochrane database of systematic reviews 20030101

• [Headache in children].

  Duodecim; laaketieteellinen aikakauskirja 20030101

• Meta-analysis of oral triptan therapy for migraine: number needed to treat and relative cost to achieve relief within 2 hours.

  Journal of managed care pharmacy : JMCP 20030101

• Impact of antimigraine compounds on cognitive processing: a placebo-controlled crossover study.

  Headache 20030101

• Does migraine preventive medication actually reduce resource utilization?

  Headache 20030101

• Endothelium-dependent relaxant responses to selective 5-HT(1B/1D) receptor agonists in the isolated middle cerebral artery of the rat.

  Journal of vascular research 20030101

• [Suppressing effect of the serotonin 5HT1B/D receptor agonist rizatriptan on calcitonin gene-related peptide (CGRP) concentration in migraine attacks].

  Neurologia i neurochirurgia polska 20030101

• The antimigraine 5-HT 1B/1D receptor agonists, sumatriptan, zolmitriptan and dihydroergotamine, attenuate pain-related behaviour in a rat model of trigeminal neuropathic pain.

  British journal of pharmacology 20021201

• Preclinical studies characterizing the anti-migraine and cardiovascular effects of the selective 5-HT1D receptor agonist PNU-142633.

  Cephalalgia : an international journal of headache 20021201

• Ergot and triptan overuse in Austria--an evaluation of clinical data and cost.

  Cephalalgia : an international journal of headache 20021201

• Treatment functional GI disease: the complex pharmacology of serotonergic drugs.

  British journal of clinical pharmacology 20021201

• Relief for menstruation-related migraines.

  AWHONN lifelines 20021201

• Sumatriptan versus eletriptan: which is best?

  The Lancet. Neurology 20021201

• Unexplained fitting in three parturients suffering from postdural puncture headache.

  British journal of anaesthesia 20021101

• 5-HT1-receptor agonist sumatriptan modifies gastric size after 500 ml of water in dyspeptic patients and normal subjects.

  Digestive diseases and sciences 20021101

• Sumatriptan nasal spray for migraine: a review of studies in patients aged 17 years and younger.

  International journal of clinical practice 20021101

• The pharmacokinetics of sumatriptan when administered with norethindrone 1 mg/ethinyl estradiol 0.035 mg in healthy volunteers.

  Clinical therapeutics 20021101

• Eletriptan vs sumatriptan: a double-blind, placebo-controlled, multiple migraine attack study.

  Neurology 20021022

• Triptans (serotonin, 5-HT1B/1D agonists) in migraine: detailed results and methods of a meta-analysis of 53 trials.

  Cephalalgia : an international journal of headache 20021001

• Sumatriptan scavenges superoxide, hydroxyl, and nitric oxide radicals: in vitro electron spin resonance study.

  Headache 20021001

• Triptans versus analgesics.

  Headache 20021001

• Development and validation of an LC assay for sumatriptan succinate residues on surfaces in the manufacture of pharmaceuticals.

  Journal of pharmaceutical and biomedical analysis 20020905

• Treatment of migraine.

  The New England journal of medicine 20020905

• Amplification of sumatriptan-induced contractions with phenylephrine, histamine and KCl in the isolated human mesenteric artery: in-vitro evidence for sumatriptan-induced mesenteric ischaemia.

  Naunyn-Schmiedeberg's archives of pharmacology 20020901

• Sumatriptan-associated ischemic colitis.

  Digestive diseases and sciences 20020901

• Decreased sensitivity of 5-HT1D receptors in chronic tension-type headache.

  Headache 20020901

• The hazards of medication refills by telephone.

  Headache 20020901

• Cerebral vasoconstriction and stroke after use of serotonergic drugs.

  Neurology 20020827

• Non-invasive assessment of selective 5-HT(1B/1D)-receptor agonist-induced peripheral vascular effects in humans: comparison of different techniques.

  European journal of clinical pharmacology 20020801

• Sumatriptan-induced chest symptoms in Japanese.

  Internal medicine (Tokyo, Japan) 20020801

• Evidence against strong correlation between chest symptoms and ischemic coronary changes after subcutaneous sumatriptan injection.

  Internal medicine (Tokyo, Japan) 20020801

• The comparative clinical and economic benefits of drugs should be established and discussed as part of any formulary decision process.

  The American journal of managed care 20020801

• Mechanisms of action of the 5-HT1B/1D receptor agonists.

  Archives of neurology 20020701

• Almotriptan is an effective and well-tolerated treatment for migraine pain: results of a randomized, double-blind, placebo-controlled clinical trial.

  Cephalalgia : an international journal of headache 20020701

• Effects of sumatriptan on cerebral blood flow under normo- and hypercapnia in rats.

  Cephalalgia : an international journal of headache 20020701

• Integrating the triptans into clinical practice.

  Current opinion in neurology 20020601

• Clinical and pathophysiological characteristics of acute-onset functional dyspepsia.

  Gastroenterology 20020601

• The name of a drug used for the treatment of migraine.

  European journal of public health 20020601

• 5-Hydroxytryptamine(1B/1D) and 5-hydroxytryptamine1F receptors inhibit capsaicin-induced c-fos immunoreactivity within mouse trigeminal nucleus caudalis.

  Cephalalgia : an international journal of headache 20020601

• [The latest in headache treatment].

  Atencion primaria 20020531

• Comparison of contractile responses to donitriptan and sumatriptan in the human middle meningeal and coronary arteries.

  European journal of pharmacology 20020517

• Agonist-directed trafficking explaining the difference between response pattern of naratriptan and sumatriptan in rabbit common carotid artery.

  British journal of pharmacology 20020501

• Involvement of 5-HT1B and 5-HT1D receptors in sumatriptan mediated vasocontractile response in rabbit common carotid artery.

  British journal of pharmacology 20020501

• CNS effects of sumatriptan and rizatriptan in healthy female volunteers.

  Cephalalgia : an international journal of headache 20020501

• A pharmacokinetic interaction study between butorphanol and sumatriptan nasal sprays in healthy subjects: importance of the timing of butorphanol administration.

  Cephalalgia : an international journal of headache 20020501

• Hereditary haemochromatosis in two cousins with cluster headache.

  Cephalalgia : an international journal of headache 20020501

• Triptans: do they differ?

  Current pain and headache reports 20020401

• Triptans: are they all the same?

  Current pain and headache reports 20020401

• Successful treatment of threatening limb loss ischemia of the upper limb caused by ergotamine. A case report and review of the literature.

  The Journal of cardiovascular surgery 20020401

• Cryptic pituitary hemorrhage presenting with headache.

  Headache 20020401

• Migraine, Midrin, and Imitrex.

  Headache 20020401

• Mixing sumatriptan.

  Headache 20020401

• The pharmacokinetics of sumatriptan when administered with clarithromycin in healthy volunteers.

  Clinical therapeutics 20020401

• Pharmacology of the selective 5-HT(1B/1D) agonist frovatriptan.

  Headache 20020401

• Tolerability and safety of frovatriptan with short- and long-term use for treatment of migraine and in comparison with sumatriptan.

  Headache 20020401

• Intractable eye pain: indication for triptans.

  Cephalalgia : an international journal of headache 20020401

• Triptan medications to treat acute migraine.

  Lancet (London, England) 20020330

• Triptan medications to treat acute migraine.

  Lancet (London, England) 20020330

• Triptan medications to treat acute migraine.

  Lancet (London, England) 20020330

• [Triptanes are still effective in the middle of a migraine attack. Best effect before reaching high point].

  MMW Fortschritte der Medizin 20020328

• Pharmacoeconomic evidence and considerations for triptan treatment of migraine.

  Expert opinion on pharmacotherapy 20020301

• 5-HT1B-receptors and vascular reactivity in human isolated blood vessels: assessment of the potential craniovascular selectivity of sumatriptan.

  British journal of clinical pharmacology 20020301

• Serotonin-induced contraction in mesenteric resistance arteries: signaling and changes in deoxycorticosterone acetate-salt hypertension.

  Hypertension (Dallas, Tex. : 1979) 20020301

• New treatments in cluster headache.

  Current neurology and neuroscience reports 20020301

• Characterization of sumatriptan-induced contractions in human isolated blood vessels using selective 5-HT(1B) and 5-HT(1D) receptor antagonists and in situ hybridization.

  Cephalalgia : an international journal of headache 20020301

• Serotonergic functioning in children with oppositional defiant disorder: a sumatriptan challenge study.

  Biological psychiatry 20020215

• [Migraine has to be treated. Otherwise a stroke threatens].

  MMW Fortschritte der Medizin 20020214

• Cluster headache: a prospective clinical study with diagnostic implications.

  Neurology 20020212

• Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model.

  Nature medicine 20020201

• Sumatriptan use in patients with migraine.

  Mayo Clinic proceedings 20020201

• [Treatment of idiopathic headache in childhood - recommendations of the German Migraine and Headache Society (DMKG)].

  Schmerz (Berlin, Germany) 20020201

• Cost savings in migraine associated with less chest pain on new triptan therapy.

  The American journal of managed care 20020201

• Almotriptan versus sumatriptan in migraine treatment: direct medical costs of managing adverse chest symptoms.

  The American journal of managed care 20020201

• Re: Zakrzewska JM. Cluster headache: review of the literature. Br J Oral Maxillofac Surg 2001; 39: 103-113.

  The British journal of oral & maxillofacial surgery 20020201

• Comparison of triptan tablet consumption per attack: a prospective study of migraineurs in Spain.

  Headache 20020201

• Modification of serotonin neuron properties in mice lacking 5-HT1A receptors.

  European journal of pharmacology 20020125

• [New triptanes in control of migraine attacks. More rapid onset of action--more efficient reduction of pain].

  MMW Fortschritte der Medizin 20020124

• [Treatment of migraine in patients with hypertension and ischemic heart disease].

  Ideggyogyaszati szemle 20020120

• Calcium-antagonistic activity of sumatriptan in the rat anococcygeus muscle.

  Pharmacology 20020101

• Sumatriptan challenge in bipolar patients with and without migraine: a neuroendocrine study of 5-HT1D receptor function.

  International clinical psychopharmacology 20020101

• Treatment of acute cluster headache with 20 mg sumatriptan nasal spray--an open pilot study.

  Journal of neurology 20020101

• Clinical benefits of early triptan therapy for migraine.

  Headache 20020101

• Tripstar: a comprehensive patient-based approach to compare triptans.

  Headache 20020101

• Almotriptan reduces the incidence of migraine-associated symptoms: a pooled analysis.

  Headache 20020101

• Impact of chest pain on cost of migraine treatment with almotriptan and sumatriptan.

  Headache 20020101

• Is there a preferred triptan?

  Headache 20020101

• Almotriptan increases sustained pain-free outcomes in acute migraine: results from three controlled clinical trials.

  Headache 20020101

• Evidence-based assessment of pregnancy outcome after sumatriptan exposure.

  Headache 20020101

• Refractory obsessive-compulsive disorder: state-of-the-art treatment.

  The Journal of clinical psychiatry 20020101

• Practical approaches to migraine management.

  CNS drugs 20020101

• [Use and misuse of triptans: a case report].

  Therapie 20020101

• Clinical pharmacokinetics of intranasal sumatriptan.

  Clinical pharmacokinetics 20020101

• New insights into the molecular actions of serotonergic antimigraine drugs.

  Pharmacology & therapeutics 20020101

• [How do sumatriptan and co. work? The action mechanisms of triptans].

  Pharmazie in unserer Zeit 20020101

• [Which triptan is best? Rating of triptans in migraine treatment].

  Pharmazie in unserer Zeit 20020101

• Restoring migraine sufferers' ability to function normally: a comparison of rizatriptan and other triptans in randomized trials.

  European neurology 20020101

• An introduction to migraine: from ancient treatment to functional pharmacology and antimigraine therapy.

  Proceedings of the Western Pharmacology Society 20020101

• Lack of sumatriptan-induced aortic contraction or relaxation: 5-HT1B receptor protein detected in endothelium and smooth muscle of vasa vasorum but not aorta.

  Receptors & channels 20020101

• Cost-effectiveness of antiepileptic drugs in migraine prophylaxis.

  Headache 20020101

• Costs and outcomes of early versus delayed migraine treatment with sumatriptan.

  Headache 20020101

• [The problems of migraine headache treatment].

  Medicina (Kaunas, Lithuania) 20020101

• Transient minor improvement of high altitude headache by sumatriptan.

  High altitude medicine & biology 20020101

• A comparison of familial and sporadic migraine in a headache clinic population.

  Functional neurology 20020101

• Intracranial hemorrhages associated with sumatriptan.

  Neurology 20011226

• Intracranial hemorrhages associated with sumatriptan.

  Neurology 20011226

• Diffusion-weighted MRI used to detect in vivo modulation of cortical spreading depression: comparison of sumatriptan and tonabersat.

  Experimental neurology 20011201

• Intranasal sumatriptan in post-ECT headache: results of an open-label trial.

  The journal of ECT 20011201

• Evidence for postjunctional serotonin (5-HT1) receptors in the trigeminocervical complex.

  Annals of neurology 20011201

• Privacy issues and the monitoring of sumatriptan in the New Zealand Intensive Medicines Monitoring Programme.

  Pharmacoepidemiology and drug safety 20011201

• In vitro activity of LY393558, an inhibitor of the 5-hydroxytryptamine transporter with 5-HT(1B/1D/2) receptor antagonist properties.

  European journal of pharmacology 20011130

• [Choice of triptan in migraine].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20011130

• [Migraine therapy. NSAID are included as first choice].

  MMW Fortschritte der Medizin 20011122

• Clinical features of withdrawal headache following overuse of triptans and other headache drugs.

  Neurology 20011113

• Cost-effectiveness and cost-benefit of sumatriptan in patients with migraine.

  Mayo Clinic proceedings 20011101

• Sumatriptan responsiveness and clinical, psychiatric and psychologic features in migraine patients.

  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20011101

• Evidence-based migraine therapy.

  Cephalalgia : an international journal of headache 20011101

• Comparison of rizatriptan and other triptans on stringent measures of efficacy.

  Neurology 20011023

• [Migraine and facial pain].

  La Revue du praticien 20011015

• ABC of the upper gastrointestinal tract. Oesophagus: Atypical chest pain and motility disorders.

  BMJ (Clinical research ed.) 20011006

• Determination of degradation products of sumatriptan succinate using LC-MS and LC-MS-MS.

  Journal of pharmaceutical and biomedical analysis 20011001

• Involvement of nitric oxide in the regulation of growth hormone secretion in dogs.

  Neuroendocrinology 20011001

• Efficacy of sumatriptan in the treatment of migraine: a review of the literature.

  The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses 20011001

• Patient satisfaction with rizatriptan versus other triptans: direct head-to-head comparisons.

  International journal of clinical practice 20011001

• Mixing sumatriptan: a prospective study of stratified care using multiple formulations.

  Headache 20011001

• Efficacy and tolerability of subcutaneous sumatriptan for acute migraine: a comparison between ethnic groups.

  Headache 20011001

• Daily triptans for headache.

  Headache 20011001

• Migraine, eating disorders, and triptans: an unrecognized risk?

  Headache 20011001

• Migraine and tension-type headache reduction through pericranial muscular suppression: a preliminary report.

  Cranio : the journal of craniomandibular practice 20011001

• Assessing patient preference in migraine treatment.

  Cephalalgia : an international journal of headache 20011001

• Vascular effects of the new anti-migraine agent almotriptan on human cranial and peripheral arteries.

  Cephalalgia : an international journal of headache 20011001

• Tolerability of sumatriptan: clinical trials and postmarketing experience.

  Cephalalgia : an international journal of headache 20011001

• HT29-MTX and Caco-2/TC7 monolayers as predictive models for human intestinal absorption: role of the mucus layer.

  Journal of pharmaceutical sciences 20011001

• Have the triptans fulfilled their promise?

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20010901

• Have the triptans fulfilled their promise?

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20010901

• Have the triptans fulfilled their promise?

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20010901

• Taking St. John's wort with other drugs can be trouble.

  Mayo Clinic health letter (English ed.) 20010901

• Migraine treatment.

  Pediatrics 20010901

• [The present situation and the prospect of pain control in this country and other countries].

  Nihon rinsho. Japanese journal of clinical medicine 20010901

• Triptans are all different.

  Archives of neurology 20010901

• What matters is not the differences between triptans, but the differences between patients.

  Archives of neurology 20010901

• Preference comparison of rizatriptan ODT 10-mg and sumatriptan 50-mg tablet in migraine.

  Headache 20010901

• Effect of rizatriptan and other triptans on the nausea symptom of migraine: a post hoc analysis.

  Headache 20010901

• Immunological aspects in migraine: increase of IL-10 plasma levels during attack.

  Headache 20010901

• Reduction in the intensity of abortive migraine drug use during coumarin therapy.

  Headache 20010901

• Effects of medication use on health state in postictal migraineurs.

  Headache 20010901

• Dexamethasone decreases migraine recurrence observed after treatment with a triptan combined with a nonsteroidal anti-inflammatory drug.

  Arquivos de neuro-psiquiatria 20010901

• Safety profile of almotriptan, a new antimigraine agent. Effects on central nervous system, renal function and respiratory dynamics.

  Arzneimittel-Forschung 20010901

• Serotonergic effects and extracellular brain levels of eletriptan, zolmitriptan and sumatriptan in rat brain.

  European journal of pharmacology 20010817

• A comparison of visual analog scale and categorical ratings of headache pain in a randomized controlled clinical trial with migraine patients.

  Pain 20010801

• Effect of intranasal sumatriptan on gastric tone and sensitivity to distension.

  Digestive diseases and sciences 20010801

• A systematic review of the use of triptans in acute migraine.

  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20010801

• [Migraine headache. Severe attacks: triptans are essential].

  MMW Fortschritte der Medizin 20010719

• Craniovascular selectivity of eletriptan and sumatriptan in human isolated blood vessels.

  Neurology 20010710

• [New potent serotonin receptor agonist. Helps migraine patients even when other triptans fail].

  MMW Fortschritte der Medizin 20010705

• Establishing a standard of speed for assessing the efficacy of the serotonin(1B/1D) agonists (triptans).

  Archives of neurology 20010701

• [Effect of sumatriptan on cerebral blood flow during migraine headache: measurement by sequential SPECT used 99mTc-ECD background subtraction method].

  No to shinkei = Brain and nerve 20010701

• The efficacy and safety of sc alniditan vs. sc sumatriptan in the acute treatment of migraine: a randomized, double-blind, placebo-controlled trial.

  Cephalalgia : an international journal of headache 20010701

• An open preference study with sumatriptan 50 mg and zolmitriptan 2.5 mg in 100 migraine patients.

  Cephalalgia : an international journal of headache 20010701

• Sumatriptan overdose in episodic cluster headache: a case report of overuse without event.

  Cephalalgia : an international journal of headache 20010701

• Intranasal absorption of sumatriptan and naratriptan: no evidence of local transfer from the nasal cavities to the brain arterial blood in male rats.

  Biopharmaceutics & drug disposition 20010701

• Adenosine A(1) receptor-mediated inhibition of protein kinase A-induced calcitonin gene-related peptide release from rat trigeminal neurons.

  Molecular pharmacology 20010601

• Recent development in paediatric headache.

  Current opinion in neurology 20010601

• Oral almotriptan vs. oral sumatriptan in the abortive treatment of migraine: a double-blind, randomized, parallel-group, optimum-dose comparison.

  Archives of neurology 20010601

• [Anti-migraine drug sumatriptan succinate, a 5-HT1B/1D-receptor agonist].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20010601

• Sumatriptan can alleviate headaches due to carotid artery dissection.

  Headache 20010601

• Effect of rizatriptan in the spectrum of headache.

  Headache 20010601

• Patterns of ergotamine and sumatriptan use in the Netherlands from 1991 to 1997.

  Cephalalgia : an international journal of headache 20010601

• Modifications by sumatriptan and acetylcholine of nitric oxide-mediated neurogenic dilatation in dog cerebral arteries.

  European journal of pharmacology 20010518

• Intracranial hemorrhages associated with sumatriptan.

  Neurology 20010508

• Neurogenic inflammation in the context of migraine.

  Microscopy research and technique 20010501

• Functional immunohistochemistry of neuropeptides and nitric oxide synthase in the nerve fibers of the supratentorial dura mater in an experimental migraine model.

  Microscopy research and technique 20010501

• An in vivo rat model to study calcitonin gene related peptide release following activation of the trigeminal vascular system.

  Pain 20010501

• Zolmitriptan versus sumatriptan for the acute oral treatment of migraine: a randomized, double-blind, international study.

  European journal of neurology 20010501

• Neuroendocrine effects of subcutaneous sumatriptan in patients with migraine.

  Journal of endocrinological investigation 20010501

• [Aspirin, triptan tablet, nasal spray, injection. Even the most severe migraine capitulates].

  MMW Fortschritte der Medizin 20010419

• [Migraine: selection of therapeutic agents to be applied during its attack].

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20010410

• [Migraine: sumatriptan].

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20010410

• [Current topics: expectation for new triptans].

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20010410

• Cluster headache: review of the literature.

  The British journal of oral & maxillofacial surgery 20010401

• Sumatriptan, 5-HT(1D) receptors and obsessive-compulsive disorder.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20010401

• Delivery outcome in women who used drugs for migraine during pregnancy with special reference to sumatriptan.

  Headache 20010401

• Sumatriptan nasal spray and cognitive function during migraine: results of an open-label study.

  Headache 20010401

• Comparative study of a combination of isometheptene mucate, dichloralphenazone with acetaminophen and sumatriptan succinate in the treatment of migraine.

  Headache 20010401

• Managing migraine: strategies for successful patient outcomes.

  The Nurse practitioner 20010401

• Brain mediation of Anolis social dominance displays. III. Differential forebrain 3H-sumatriptan binding in dominant vs. submissive males.

  Brain, behavior and evolution 20010401

• Serotonin-induced hypercontraction through 5-hydroxytryptamine 1B receptors in atherosclerotic rabbit coronary arteries.

  Circulation 20010306

• Cardiovascular effects of SL65.0472, a 5-HT receptor antagonist.

  European journal of pharmacology 20010302

• Comparative effects of frovatriptan and sumatriptan on coronary and internal carotid vascular haemodynamics in conscious dogs.

  British journal of pharmacology 20010301

• Multiple 5-HT(1) autoreceptor subtypes govern serotonin release in dorsal and median raphé nuclei.

  Neuropharmacology 20010301

• Zolmitriptan versus sumatriptan comparison trial.

  Headache 20010301

• Sumatriptin vs dihydroergotamine: patient preference.

  International journal of clinical practice 20010301

• Headaches in children and adolescents: update 2001.

  Seminars in pediatric neurology 20010301

• Status migrainosus in children and adolescents.

  Seminars in pediatric neurology 20010301

• Complicated migraine and migraine variants.

  Seminars in pediatric neurology 20010301

• Gastric motor effects of triptans: open questions and future perspectives.

  Pharmacological research 20010301

• Relaxation induced by serotonin and sumatriptan in isolated guinea pig gallbladder strips.

  Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 20010301

• Acute treatment of migraine and the role of triptans.

  Current neurology and neuroscience reports 20010301

• Cortical spreading depression produces increased cGMP levels in cortex and brain stem that is inhibited by tonabersat (SB-220453) but not sumatriptan.

  Brain research 20010209

• The impact of pharmacogenetics for migraine.

  European journal of pharmacology 20010209

• [Treatment of cluster headache].

  La Revue de medecine interne 20010201

• Sumatriptan: what do we know about fetal risks?

  Headache 20010201

• Butterscotch masks the bitter taste of sumatriptan nasal spray.

  Headache 20010201

• A systematic review of the use of triptans in acute migraine.

  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20010201

• Effect of encapsulation on absorption of sumatriptan tablets: data from healthy volunteers and patients during a migraine.

  Clinical therapeutics 20010201

• Efficacy, tolerability, and patient satisfaction with 50- and 100-mg sumatriptan tablets in those initially dissatisfied with the efficacy of 50-mg sumatriptan tablets.

  Clinical therapeutics 20010201

• Economic implications of early treatment of migraine with sumatriptan tablets.

  Clinical therapeutics 20010201

• Sumatriptan: economic evidence for its use in the treatment of migraine, the Canadian comparative economic analysis.

  Cephalalgia : an international journal of headache 20010201

• A clinical trial on a plate? The potential of 384-well format solid phase extraction for high-throughput bioanalysis using liquid chromatography/tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20010101

• New abortive agents for the treatment of migraine.

  Advances in internal medicine 20010101

• Sumatriptan elicits both constriction and dilation in human and bovine brain intracortical arterioles.

  British journal of pharmacology 20010101

• Inhibition of inflammation-induced thermal hypersensitivity by sumatriptan through activation of 5-HT(1B/1D) receptors.

  Experimental neurology 20010101

• Interictal and postictal contingent negative variation in migraine without aura.

  Headache 20010101

• Unravelling the pharmacological profile of the canine external carotid vasodilator '5-HT1-like' receptors: coexistence of sympatho-inhibitory 5-HT1B and postjunctional 5-HT7 receptors.

  Naunyn-Schmiedeberg's archives of pharmacology 20010101

• pH-mediated field-amplified sample stacking of pharmaceutical cations in high-ionic strength samples.

  Electrophoresis 20010101

• Effect of sumatriptan on health care resource use among patients with migraine.

  Managed care interface 20010101

• Treatment satisfaction, functional status, and health-related quality of life of migraine patients treated with almotriptan or sumatriptan.

  Clinical therapeutics 20010101

• [First manifestation of migraine as acute confusional state: 'confusional migraine' and diagnostic problems].

  Klinische Padiatrie 20010101

• Comparison of preference for rizatriptan 10-mg wafer versus sumatriptan 50-mg tablet in migraine.

  European neurology 20010101

• When should triptans be taken during a migraine attack?

  CNS drugs 20010101

• Effectiveness of nasal sumatriptan in 5- to 12-year-old children.

  Headache 20010101

• How it started.

  Cephalalgia : an international journal of headache 20010101

• Sumatriptan by injection.

  Cephalalgia : an international journal of headache 20010101

• Clinical efficacy and tolerability of sumatriptan tablet and suppository in the acute treatment of migraine: a review of data from clinical trials.

  Cephalalgia : an international journal of headache 20010101

• The sumatriptan nasal spray: a review of clinical trials.

  Cephalalgia : an international journal of headache 20010101

• Sumatriptan in the treatment of cluster headache.

  Cephalalgia : an international journal of headache 20010101

• The sumatriptan difference.

  Cephalalgia : an international journal of headache 20010101

• Sumatriptan in paediatric and adolescent migraine.

  Cephalalgia : an international journal of headache 20010101

• Sumatriptan and naratriptan tolerability and safety: an update of post-marketing experience.

  Cephalalgia : an international journal of headache 20010101

• Bringing sumatriptan to primary care.

  Cephalalgia : an international journal of headache 20010101

• Building on the sumatriptan experience: the development of naratriptan.

  Cephalalgia : an international journal of headache 20010101

• Looking forward: the expanding utility of sumatriptan and naratriptan.

  Cephalalgia : an international journal of headache 20010101

• Different approaches to valuing the lost productivity of patients with migraine.

  PharmacoEconomics 20010101

• Migraines.

  Clinical neuropharmacology 20010101

• Triptans in the treatment of basilar migraine and migraine with prolonged aura.

  Headache 20010101

• Imigran: Ten years of improving the lives of migraine patients. Rome, 24 March 2000. Proceedings of a conference.

  Cephalalgia : an international journal of headache 20010101

• Intraoral chilling versus oral sumatriptan for acute migraine.

  Heart disease (Hagerstown, Md.) 20010101

• Medication overuse headache.

  Current medical research and opinion 20010101

• Ergotamine, dihydroergotamine: current uses and problems.

  Current medical research and opinion 20010101

• Sumatriptan: pharmacological basis and clinical results.

  Current medical research and opinion 20010101

• Zolmitriptan: differences from sumatriptan.

  Current medical research and opinion 20010101

• Rizatriptan: pharmacological differences from sumatriptan and clinical results.

  Current medical research and opinion 20010101

• Eletriptan: pharmacological differences and clinical results.

  Current medical research and opinion 20010101

• Almotriptan: pharmacological differences and clinical results.

  Current medical research and opinion 20010101

• Comparative aspects of triptans in treating migraine.

  Clinical cornerstone 20010101

• Pharmacological characterization of almotriptan: an indolic 5-HT receptor agonist for the treatment of migraine.

  European journal of pharmacology 20001220

• Cardiovascular safety profile of almotriptan, a new indolic derivative for the treatment of migraine.

  European journal of pharmacology 20001220

• Triptans in migraine: a comparative review of pharmacology, pharmacokinetics and efficacy.

  Drugs 20001201

• Are triptans with enhanced lipophilicity used for the acute treatment of migraine associated with an increased consulting rate for depressive illness?

  Cephalalgia : an international journal of headache 20001001

• Comparison of naratriptan and sumatriptan in recurrence-prone migraine patients. Naratriptan International Recurrence Study Group.

  Clinical therapeutics 20000801

• Atrial fibrillation associated with sumatriptan.

  BMJ (Clinical research ed.) 20000729

• Headache relief after sumatriptan in a patient with pituitary macroadenoma.

  Headache 20000501

• Transient global amnesia, migraine, thalamic infarct, dihydroergotamine, and sumatriptan.

  Headache 20000401

• Alteration in nature of cluster headache during subcutaneous administration of sumatriptan.

  Headache 20000101

• Vestibular schwannoma surgery and headache.

  Acta oto-laryngologica. Supplementum 20000101

• Sumatriptan overuse in episodic cluster headache: lack of adverse events, rebound syndromes, drug dependence and tachyphylaxis.

  Functional neurology 20000101

• 2000 Wolfe Award. Sumatriptan for the range of headaches in migraine sufferers: results of the Spectrum Study.

  Headache 20000101

• Identification of an amino acid residue important for binding of methiothepin and sumatriptan to the human 5-HT(1B) receptor.

  European journal of pharmacology 19990910

• Open-labeled long-term study of the efficacy, safety, and tolerability of subcutaneous sumatriptan in acute migraine treatment.

  Cephalalgia : an international journal of headache 19990901

• Single photon emission computed tomography of the brain with Tc-99m HMPAO during sumatriptan challenge in obsessive-compulsive disorder: investigating the functional role of the serotonin auto-receptor.

  Progress in neuro-psychopharmacology & biological psychiatry 19990801

• An unusual case of renal vein thrombosis in a man taking sumatriptan.

  BJU international 19990601

• Profiles of 5-HT 1B/1D agonists in acute migraine with special reference to second generation agents.

  Acta neurologica Belgica 19990601

• Dramatic headache relief after sumatriptan in a patient with a pituitary macroadenoma.

  Headache 19990601

• Prospective large-scale study of the tolerability of subcutaneous sumatriptan injection for acute treatment of migraine.

  Cephalalgia : an international journal of headache 19990501

• Postpartum cerebral angiopathy associated with the administration of sumatriptan and dihydroergotamine--a case report.

  Intensive care medicine 19990501

• The association of the combination of sumatriptan and methysergide in myocardial infarction in a premenopausal woman.

  Archives of internal medicine 19990308

• Characterisation of the 5-HT receptor binding profile of eletriptan and kinetics of [3H]eletriptan binding at human 5-HT1B and 5-HT1D receptors.

  European journal of pharmacology 19990305

• The pharmacodynamics of sumatriptan in nitroglycerin-induced headache.

  Journal of clinical pharmacology 19990101

• Sumatriptan treatment for migraine in a health maintenance organization: economic, humanistic, and clinical outcomes.

  Clinical therapeutics 19990101

• Sumatriptan and ergotamine overuse and drug-induced headache: a clinicoepidemiologic study.

  Clinical neuropharmacology 19990101

• Fatal cardiac arrhythmia after oral sumatriptan.

  Headache 19990101

• Safety trial with the 5HT1B/1D agonist avitriptan (BMS-180048) in patients with migraine who have experienced pressure, tightness, and/or pain in the chest, neck, and/or throat following sumatriptan.

  Cephalalgia : an international journal of headache 19981001

• Imitrex.

  Cephalalgia : an international journal of headache 19981001

• Ischemic colitis and sumatriptan use.

  Archives of internal medicine 19980928

• Coronary side-effect potential of current and prospective antimigraine drugs.

  Circulation 19980707

• Isochroman-6-carboxamides as highly selective 5-HT1D agonists: potential new treatment for migraine without cardiovascular side effects.

  Journal of medicinal chemistry 19980618

• Cardiac arrest and myocardial infarction immediately after sumatriptan injection.

  Annals of internal medicine 19980515

• Agonistic properties of alniditan, sumatriptan and dihydroergotamine on human 5-HT1B and 5-HT1D receptors expressed in various mammalian cell lines.

  British journal of pharmacology 19980401

• [Evaluation of efficacy and tolerance sumatriptan at a dose of 50 mg in treatment of migraine attack].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 19980301

• Pharmacological analysis of the haemodynamic effects of 5-HT1B/D receptor agonists in the normotensive rat.

  British journal of pharmacology 19980101

• Sumatriptan-induced axial dystonia in a patient with cluster headache.

  Cephalalgia : an international journal of headache 19980101

• Oral rizatriptan versus oral sumatriptan: a direct comparative study in the acute treatment of migraine. Rizatriptan 030 Study Group.

  Headache 19980101

• Characteristics and determinants of sumatriptan-associated chest pain.

  Archives of neurology 19971101

• A study of the effects of sumatriptan on myocardial perfusion in healthy female migraineurs using 13NH3 positron emission tomography.

  Neurology 19970601

• Agonist activity of antimigraine drugs at recombinant human 5-HT1A receptors: potential implications for prophylactic and acute therapy.

  Naunyn-Schmiedeberg's archives of pharmacology 19970601

• Naratriptan: biological profile in animal models relevant to migraine.

  Cephalalgia : an international journal of headache 19970501

• The site of common side effects of sumatriptan.

  Headache 19970501

• Interactions of GR127935, a 5-HT(1B/D) receptor ligand, with functional 5-HT receptors.

  Naunyn-Schmiedeberg's archives of pharmacology 19970401

• Sumatriptan-associated myocardial infarction: report of case with attention to potential risk factors.

  The Journal of the American Osteopathic Association 19970301

• Akathisia and acute dystonia induced by sumatriptan.

  Journal of neurology 19970201

• Drug-induced chest pain and myocardial infarction. Reports to a national centre and review of the literature.

  European journal of clinical pharmacology 19970101

• Chest symptoms after sumatriptan: a two-year clinical practice review in 735 consecutive migraine patients.

  Cephalalgia : an international journal of headache 19961201

• Sumatriptan and panic-like symptoms.

  The American journal of psychiatry 19961101

• Pharmacokinetic and pharmacodynamic profiles of sumatriptan in migraine patients with headache recurrence or no response.

  Clinical pharmacology and therapeutics 19961001

• Headache induced by a nitric oxide donor (nitroglycerin) responds to sumatriptan. A human model for development of migraine drugs.

  Cephalalgia : an international journal of headache 19961001

• Serotonin syndrome complicating migraine pharmacotherapy.

  Cephalalgia : an international journal of headache 19960801

• Easy therapeutical management of sumatriptan-induced daily headache.

  Neurology 19960701

• Changes in cerebral blood flow velocity after treatment with sumatriptan or placebo and implications for the pathophysiology of migraine.

  Journal of the neurological sciences 19960601

• Vasospasm-induced myocardial infarction with sumatriptan.

  Headache 19960501

• EEG and topographic frequency analysis in migraine attack before and after sumatriptan infusion.

  Headache 19960201

• Renal papillary necrosis following emergency department treatment of migraine.

  The Journal of emergency medicine 19960101

• Angioedema associated with sumatriptan administration.

  The American journal of medicine 19951201

• Oral sumatriptan-associated transmural myocardial infarction.

  Neurology 19951201

• [The migraine agent sumatriptan (Imigran) and coronary heart disease].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 19950820

• Cardiac arrest following use of sumatriptan.

  Neurology 19950601

• Glyceryl trinitrate reversal of post-sumatriptan coronary artery narrowing.

  Lancet (London, England) 19950527

• [The migraine remedy sumatriptan (Imigran) and coronary heart disease].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 19950520

• The effects of oral sumatriptan, a 5-HT1 receptor agonist, on circulating ACTH and cortisol concentrations in man.

  British journal of clinical pharmacology 19950401

• Sumatriptan and daily headache.

  Journal of neurology, neurosurgery, and psychiatry 19950401

• Buspirone, but not sumatriptan, induces miosis in humans: relevance for a serotoninergic pupil control.

  Clinical pharmacology and therapeutics 19950301

• Increase in plasma calcitonin gene-related peptide from the extracerebral circulation during nitroglycerin-induced cluster headache attack.

  Pain 19950201

• Recurrent depression after sumatriptan administration for treatment of migraine.

  Journal of clinical psychopharmacology 19950201

• Unstable angina pectoris associated with Imitrex therapy.

  Catheterization and cardiovascular diagnosis 19950201

• Fatal cerebellar infarction in a migraine sufferer whilst receiving sumatriptan.

  Intensive care medicine 19950101

• High efficacy and low frequency of headache recurrence after oral sumatriptan. The Oral Sumatriptan Italian Study Group.

  The Journal of international medical research 19950101

• Sumatriptan-induced chest pain.

  Lancet (London, England) 19941217

• Sumatriptan-induced chest pain.

  Lancet (London, England) 19941126

• Sumatriptan-induced chest pain.

  Lancet (London, England) 19941126

• Is chest pain after sumatriptan oesophageal in origin?

  Lancet (London, England) 19941008

• Oral sumatriptan: effect of a second dose, and incidence and treatment of headache recurrences.

  Cephalalgia : an international journal of headache 19941001

• Ergotamine-induced headache can be sustained by sumatriptan daily intake.

  Cephalalgia : an international journal of headache 19941001

• [Use of sumatriptan (Imigran) in a female patient with coronary spasm].

  Nederlands tijdschrift voor geneeskunde 19940910

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  Giornale italiano di cardiologia 19940701

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• Sumatriptan-induced stroke in sagittal sinus thrombosis.

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• Function of the peripheral serotoninergic pathways in migraine: a proposal for an experimental model.

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• Adverse reactions attributed to sumatriptan. A postmarketing study in general practice.

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• Sumatriptan blocks neurogenic inflammation in the peripheral nerve trunk.

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• Transient resolution of headache in giant cell temporal arteritis after sumatriptan.

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• Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase.

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• Coronary vasospasm induced by subcutaneous sumatriptan.

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• Subcutaneous sumatriptan in the treatment of headache during withdrawal from drug-induced headache.

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