10366-35-5 | 2-Chloronicotinamide

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$15.00	$10.00
10g	98%	in stock	$20.00	$14.00
25g	98%	in stock	$33.00	$23.00
100g	98%	in stock	$86.00	$60.00
500g	98%	in stock	$425.00	$297.00

Description

• Catalog Number: AB61903
• Chemical Name: 2-Chloronicotinamide
• CAS Number: 10366-35-5
• Molecular Formula: C6H5ClN2O
• Molecular Weight: 156.5697
• MDL Number: MFCD00006237
• SMILES: NC(=O)c1cccnc1Cl

Computed Properties

• Complexity: 140
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 1.6

Upstream Synthesis Route

2-Chloronicotinamide, also known as 2-chloro-3-pyridinecarboxamide, is a valuable building block in chemical synthesis due to its versatile reactivity and unique properties. This compound serves as a key intermediate in the synthesis of various pharmaceuticals, agrochemicals, and functional materials.In chemical synthesis, 2-Chloronicotinamide is commonly used as a precursor for the synthesis of heterocyclic compounds, such as pyrazolo[1,5-a]pyrimidines and pyridine derivatives, which exhibit a wide range of biological activities. Its ability to undergo various functional group transformations, such as nucleophilic substitution, condensation, and coupling reactions, makes it a valuable tool for organic chemists in designing and accessing complex molecular structures.Furthermore, 2-Chloronicotinamide can be utilized in the development of novel catalysts and ligands for organometallic reactions, as well as in the production of specialty chemicals and polymer materials. Its specific chemical reactivity and compatibility with different reaction conditions make it a versatile compound for constructing diverse molecular architectures with tailored properties and functionalities.

Literature

• 2,2'-(Diselane-1,2-di-yl)dinicotinamide N,N'-dimethyl-formamide disolvate.

  Acta crystallographica. Section E, Structure reports online 20100501

• 2-Chloro-pyridine-3-carboxamide.

  Acta crystallographica. Section E, Structure reports online 20090201