103733-65-9 | D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$15.00	$10.00
1g	95%	in stock	$16.00	$11.00
5g	95%	in stock	$25.00	$17.00
25g	95%	in stock	$39.00	$27.00
100g	95%	in stock	$153.00	$107.00

Description

• Catalog Number: AD46922
• Chemical Name: D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
• CAS Number: 103733-65-9
• Molecular Formula: C10H11NO2
• Molecular Weight: 177.19983999999997
• MDL Number: MFCD00144038
• SMILES: OC(=O)[C@@H]1NCc2c(C1)cccc2

Computed Properties

• Complexity: 205
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: -1.3

Upstream Synthesis Route

The application of (R)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid in chemical synthesis is essential in the preparation of various pharmaceutical compounds and organic materials. As a chiral building block, this compound serves as a key intermediate for the synthesis of biologically active molecules, particularly in the development of drugs targeting neurological disorders, anti-inflammatory agents, and other therapeutic agents. Its unique structural features make it a versatile precursor in the creation of complex organic molecules through strategic synthetic routes. The stereochemistry of (R)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid plays a crucial role in determining the specific properties and activities of the final products, making it a valuable component in the chemical synthesis of advanced compounds.

Literature

• Capillary electrophoresis for diastereomers of (R,S)-tetrahydroisoquinoline-3-carboxylic acid derivatized with (R)-4-nitro-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole: effect of molecular geometries.

  Journal of chromatographic science 20050301