1038-95-5 | Tri-p-tolylphosphine

Packsize	Purity	Availability	Price	Discounted Price
10g	95%	in stock	$13.00	$9.00
25g	95%	in stock	$15.00	$10.00
100g	95%	in stock	$46.00	$32.00
500g	95%	in stock	$206.00	$145.00

Description

• Catalog Number: AB79927
• Chemical Name: Tri-p-tolylphosphine
• CAS Number: 1038-95-5
• Molecular Formula: C21H21P
• Molecular Weight: 304.36520099999996
• MDL Number: MFCD00008542
• SMILES: Cc1ccc(cc1)P(c1ccc(cc1)C)c1ccc(cc1)C
• NSC Number: 97371

Computed Properties

• Complexity: 263
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 22
• Rotatable Bond Count: 3
• XLogP3: 5.7

Upstream Synthesis Route

Tri-p-tolylphosphine, also known as Tri(m-tolyl)phosphine or tris(3-methylphenyl)phosphine, is a versatile organic phosphine ligand commonly used in chemical synthesis. This compound has gained popularity in various synthetic methodologies due to its unique properties and diverse applications.In chemical synthesis, Tri-p-tolylphosphine serves as an effective ligand in transition metal-catalyzed reactions. It can coordinate to metals such as palladium, platinum, copper, and nickel, facilitating a wide range of catalytic transformations. One of its key roles is to stabilize and activate metal complexes, promoting efficient catalysis and enhancing selectivity in various organic transformations.Additionally, Tri-p-tolylphosphine is frequently employed in cross-coupling reactions, including Suzuki-Miyaura, Heck, and Sonogashira couplings. By forming stable complexes with transition metals, this phosphine ligand enables the formation of new carbon-carbon and carbon-heteroatom bonds, facilitating the synthesis of complex organic molecules.Moreover, Tri-p-tolylphosphine can also participate in other important reactions, such as hydrogenation, hydrosilylation, and C-H activation. Its ability to modulate the reactivity and selectivity of transition metal catalysts makes it a valuable tool for the construction of diverse chemical structures in organic synthesis.Overall, Tri-p-tolylphosphine plays a crucial role in modern synthetic chemistry by enabling the efficient and selective formation of new chemical bonds, making it an indispensable reagent for the development of novel materials and pharmaceuticals.