103862-55-1 | 5-Bromo-8-methoxy-2-methylquinoline

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$106.00	$74.00
250mg	98%	in stock	$132.00	$92.00
1g	98%	in stock	$387.00	$271.00
5g	98%	in stock	$1,132.00	$793.00

Description

• Catalog Number: AE08994
• Chemical Name: 5-Bromo-8-methoxy-2-methylquinoline
• CAS Number: 103862-55-1
• Molecular Formula: C11H10BrNO
• Molecular Weight: 252.1072
• MDL Number: MFCD04966993
• SMILES: COc1ccc(c2c1nc(C)cc2)Br

Computed Properties

• Complexity: 200
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 3.3

Upstream Synthesis Route

The application of 5-Bromo-8-methoxy-2-methylquinoline in chemical synthesis is particularly valuable due to its versatile reactivity and unique structural features. As a substituted quinoline derivative, this compound serves as a key building block in the synthesis of various pharmaceutical agents and agrochemicals. Its strategic position within the quinoline backbone enables it to participate in diverse transformations, facilitating the introduction of functional groups and stereochemical complexities into target molecules. Furthermore, the presence of the bromo and methoxy substituents enhances the compound's compatibility with a wide range of coupling reactions, making it a highly sought-after intermediate in modern synthetic methods.

Literature

• Electrophilic aromatic addition reaction: electrophilic attack at an aromatic H substituent position.

  The Journal of organic chemistry 20050218