103863-14-5 | 4-Phenylnicotinic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$338.00	$236.00
1g	95%	in stock	$839.00	$587.00
5g	95%	in stock	$2,491.00	$1,744.00

Description

• Catalog Number: AD46302
• Chemical Name: 4-Phenylnicotinic acid
• CAS Number: 103863-14-5
• Molecular Formula: C12H9NO2
• Molecular Weight: 199.2054
• MDL Number: MFCD04114252
• SMILES: OC(=O)c1cnccc1c1ccccc1

Computed Properties

• Complexity: 224
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• XLogP3: 2

Upstream Synthesis Route

4-Phenylnicotinic acid serves as a versatile building block in chemical synthesis due to its unique structural properties and reactivity. This compound is widely utilized in the pharmaceutical industry as a key intermediate in the synthesis of various bioactive molecules, pharmaceuticals, and agrochemicals. Its ability to undergo functional group transformations and form diverse chemical bonds makes it a valuable tool for organic chemists seeking to construct complex molecular frameworks. In addition, 4-Phenylnicotinic acid plays a crucial role in the development of novel drugs, as its incorporation into drug molecules can enhance their potency, selectivity, and pharmacokinetic properties. Furthermore, this compound is employed in the preparation of ligands for metal-catalyzed reactions, providing ligands with tailored steric and electronic properties to facilitate efficient catalysis in organic transformations.

Literature

• Syntheses of nicotinamide riboside and derivatives: effective agents for increasing nicotinamide adenine dinucleotide concentrations in mammalian cells.

  Journal of medicinal chemistry 20071227