10389-51-2 | 4-(4-Nitrophenyl)morpholine

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$14.00	$10.00
5g	98%	in stock	$24.00	$17.00
25g	98%	in stock	$55.00	$39.00
100g	98%	in stock	$124.00	$87.00
500g	98%	in stock	$471.00	$330.00

Description

• Catalog Number: AB44702
• Chemical Name: 4-(4-Nitrophenyl)morpholine
• CAS Number: 10389-51-2
• Molecular Formula: C10H12N2O3
• Molecular Weight: 208.2139
• MDL Number: MFCD00023317
• SMILES: [O-][N+](=O)c1ccc(cc1)N1CCOCC1
• NSC Number: 27271

Computed Properties

• Complexity: 215
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• XLogP3: 1.2

Upstream Synthesis Route

4-(4-Nitrophenyl)morpholine is a versatile compound used in chemical synthesis due to its unique properties and reactivity. This molecule serves as a valuable building block in organic chemistry, particularly in the development of pharmaceuticals, agrochemicals, and materials science. Its distinctive structure consists of a morpholine ring attached to a nitrophenyl group, offering a range of functional groups for further modifications and derivatizations.In chemical synthesis, 4-(4-Nitrophenyl)morpholine can be employed as a key intermediate in the production of various compounds. Its morpholine ring provides a cyclic amine moiety that can participate in important reactions such as amidation, acylation, and nucleophilic substitution. The nitrophenyl group, on the other hand, offers a platform for introducing aromatic functionalities or serving as a directing group in selective transformations.One significant application of 4-(4-Nitrophenyl)morpholine is its utility in the synthesis of bioactive molecules and pharmaceutical compounds. By utilizing the reactivity of both the morpholine and nitrophenyl moieties, chemists can efficiently construct complex structures with desired pharmacological properties. Additionally, this compound has found use in the preparation of advanced materials, such as polymers, dyes, and specialty chemicals, where its unique reactivity and functionality contribute to the formation of tailored structures.Overall, the strategic incorporation of 4-(4-Nitrophenyl)morpholine in chemical synthesis enables the rapid assembly of diverse molecular architectures with precise control over functional groups and stereochemistry. Its versatility and synthetic utility make it a valuable tool for researchers and synthetic chemists seeking to access novel compounds for various applications in the fields of pharmaceuticals and materials science.

Literature

• 4-(4-Nitro-phen-yl)morpholine.

  Acta crystallographica. Section E, Structure reports online 20120401

• 4-(4-Nitro-benz-yl)morpholine.

  Acta crystallographica. Section E, Structure reports online 20110401

• Controlled synthesis of water-dispersible faceted crystalline copper nanoparticles and their catalytic properties.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20100917

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Synthesis of Schiff bases of 4-(4-aminophenyl)-morpholine as potential antimicrobial agents.

  European journal of medicinal chemistry 20050201