104-81-4 | 4-Methylbenzyl bromide

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$25.00	$18.00
25g	98%	in stock	$148.00	$104.00

Description

• Catalog Number: AB67973
• Chemical Name: 4-Methylbenzyl bromide
• CAS Number: 104-81-4
• Molecular Formula: C8H9Br
• Molecular Weight: 185.0611
• MDL Number: MFCD00000181
• SMILES: BrCc1ccc(cc1)C
• NSC Number: 8050

Computed Properties

• Complexity: 72.6
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Rotatable Bond Count: 1
• XLogP3: 3

Upstream Synthesis Route

4-Methylbenzyl bromide, also known as p-tolyl bromide, is a valuable organic compound widely used in chemical synthesis. It serves as a versatile building block in the preparation of various organic compounds. In organic chemistry, 4-Methylbenzyl bromide can undergo nucleophilic substitution reactions, where the bromine atom is replaced by nucleophiles such as amines, thiols, or cyanide ions.One of the key applications of 4-Methylbenzyl bromide is in the synthesis of pharmaceuticals and agrochemicals. By using 4-Methylbenzyl bromide as a starting material, chemists can introduce the p-tolyl group into target molecules, imparting specific chemical and biological properties. This compound is particularly useful in the synthesis of antiviral drugs, antibiotics, and insecticides.Additionally, 4-Methylbenzyl bromide is utilized in the production of fragrances and flavors. Its unique chemical structure contributes to the aromatic profile of various perfumes, cosmetics, and food products. Through controlled chemical reactions, chemists can modify the p-tolyl group to achieve specific fragrance notes and enhance the overall scent profile of a product.Furthermore, 4-Methylbenzyl bromide plays a crucial role in the preparation of specialty chemicals and advanced materials. It can be incorporated into polymers, dyes, and surfactants, where its presence influences the physical and chemical properties of the final product. The versatility of 4-Methylbenzyl bromide in chemical synthesis allows for the creation of diverse compounds with tailored functionalities for various industrial applications.

Literature

• 1,2-Bis(4-methyl-benz-yl)diselane.

  Acta crystallographica. Section E, Structure reports online 20120401

• Distributed Drug Discovery, Part 3: using D(3) methodology to synthesize analogs of an anti-melanoma compound.

  Journal of combinatorial chemistry 20090112

• Synthesis, structure, and redox properties of N-confused bis(porphyrinatonickel(II)) linked by o-xylene.

  Inorganic chemistry 20070305

• Synthesis of new N-quaternary-3-benzamidoquinuclidinium salts.

  Molecules (Basel, Switzerland) 20060928

• Major congenital malformations and residential proximity to a regional industrial park including a national toxic waste site: an ecological study.

  Environmental health : a global access science source 20060101