104-92-7 | 4-Bromoanisole

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$15.00	$10.00
5g	97%	in stock	$16.00	$11.00
25g	97%	in stock	$20.00	$14.00
100g	97%	in stock	$34.00	$24.00
500g	97%	in stock	$109.00	$76.00
5kg	97%	in stock	$979.00	$685.00
10kg	97%	in stock	$1,824.00	$1,277.00

Description

• Catalog Number: AB51432
• Chemical Name: 4-Bromoanisole
• CAS Number: 104-92-7
• Molecular Formula: C7H7BrO
• Molecular Weight: 187.0339
• MDL Number: MFCD00000097
• SMILES: COc1ccc(cc1)Br
• NSC Number: 8042

Computed Properties

• Complexity: 77
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 2.8

Upstream Synthesis Route

4-Bromoanisole is a versatile chemical compound essential for various applications in chemical synthesis. It serves as a key building block for the creation of complex organic molecules in the pharmaceutical, agrochemical, and materials science industries. Due to its bromine substituent, 4-Bromoanisole acts as an effective electrophile in a range of reactions, enabling the introduction of functional groups and structural modifications. Additionally, its specific properties make it valuable for the synthesis of bioactive compounds and the development of innovative materials with tailored properties for specific applications. In essence, 4-Bromoanisole plays a crucial role as a fundamental reagent in the strategic design and synthesis of advanced chemical structures.

Literature

• Replacing conventional carbon nucleophiles with electrophiles: nickel-catalyzed reductive alkylation of aryl bromides and chlorides.

  Journal of the American Chemical Society 20120411

• (5-Bromo-2-hy-droxy-phen-yl)(4-propyl-cyclo-hex-yl)methanone.

  Acta crystallographica. Section E, Structure reports online 20120401

• Air-stable Pd(R-allyl)LCl (L= Q-Phos, P(t-Bu)3, etc.) systems for C-C/N couplings: insight into the structure-activity relationship and catalyst activation pathway.

  The Journal of organic chemistry 20111007

• (5-Bromo-2-meth-oxy-phen-yl)(4-ethyl-cyclo-hex-yl)methanone.

  Acta crystallographica. Section E, Structure reports online 20110501

• Synthesis and X-ray structure determination of highly active Pd(II), Pd(I), and Pd(0) complexes of di(tert-butyl)neopentylphosphine (DTBNpP) in the arylation of amines and ketones.

  The Journal of organic chemistry 20101001

• 4-(4-Meth-oxy-phen-yl)-2-methyl-but-3-yn-2-ol.

  Acta crystallographica. Section E, Structure reports online 20100701

• Palladium complexes with a tridentate PNO ligand. Synthesis of eta1-allyl complexes and cross-coupling reactions promoted by boron compounds.

  Dalton transactions (Cambridge, England : 2003) 20100421

• 3-(3-Bromo-4-methoxy-phen-yl)-1,5-diphenyl-pentane-1,5-dione.

  Acta crystallographica. Section E, Structure reports online 20100401

• The endocytic recycling regulator EHD1 is essential for spermatogenesis and male fertility in mice.

  BMC developmental biology 20100101

• Fluorogenic derivatization of aryl halides based on the formation of biphenyl by Suzuki coupling reaction with phenylboronic acid.

  Journal of chromatography. A 20091002

• N-heterocycle carbene (NHC)-ligated cyclopalladated N,N-dimethylbenzylamine: a highly active, practical and versatile catalyst for the Heck-Mizoroki reaction.

  Organic & biomolecular chemistry 20090521

• Formation and crystallographic elucidation of stable [4 + 2]-coordinate nickel(II) N,S-heterocyclic carbene (NSHC) complexes.

  Dalton transactions (Cambridge, England : 2003) 20090314

• (E)-N'-(5-Bromo-2-methoxy-benzyl-idene)-4-methoxy-benzohydrazide.

  Acta crystallographica. Section E, Structure reports online 20081201

• Methanolysis of 4-bromobenzenediazonium ions. Effects of acidity, [MeOH] and temperature on the formation and decomposition of diazo ethers that initiate homolytic dediazoniation.

  Organic & biomolecular chemistry 20081107

• The Wurtz-Fittig reaction in the preparation of C-silylated calixarenes.

  The Journal of organic chemistry 20071012

• Isolation and characterisation of impurities in adapalene.

  Journal of pharmaceutical and biomedical analysis 20070219

• Orientational isomerism and binding ability of nonsymmetrical guests encapsulated in a self-assembling heterodimeric capsule.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20050805

• Fluorescence labeling method for aryl halides with 4-(4,5-diphenyl-1H-imidazol-2-yl)phenylboronic acid based on Suzuki coupling reaction.

  Journal of chromatography. A 20050225

• Inclusion compounds of tetrakis(4-nitrophenyl)methane: C-H...O networks, pseudopolymorphism, and structural transformations.

  Journal of the American Chemical Society 20010516