1040281-84-2 | 4-Chlorothiophen-2-boronic acid, pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$330.00	$231.00
1g	95%	in stock	$789.00	$553.00
5g	95%	in stock	$2,002.00	$1,402.00
10g	95%	in stock	$2,654.00	$1,858.00
25g	95%	in stock	$4,676.00	$3,273.00

Description

• Catalog Number: AD68906
• Chemical Name: 4-Chlorothiophen-2-boronic acid, pinacol ester
• CAS Number: 1040281-84-2
• Molecular Formula: C10H14BClO2S
• Molecular Weight: 244.546
• MDL Number: MFCD18383081
• SMILES: CC1(C)OB(OC1(C)C)c1scc(c1)Cl

Computed Properties

• Complexity: 244
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1

Upstream Synthesis Route

2-(4-Chlorothiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, also known as $name$, serves as a versatile reagent in chemical synthesis. This compound is commonly employed as a boron-containing building block in organic reactions, offering a convenient and effective way to introduce boron functionality into organic molecules. Its unique structure featuring a chlorothiophenyl group and tetramethylboronate moiety imparts specific reactivity, making it particularly useful in cross-coupling reactions.In organic synthesis, 2-(4-Chlorothiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane can participate in Suzuki-Miyaura coupling reactions, enabling the formation of carbon-carbon bonds under mild conditions. This reagent facilitates the synthesis of biaryl compounds, key structural motifs found in pharmaceuticals, agrochemicals, and materials science. Furthermore, its boron atom can undergo diverse transformations, such as oxidation to boronic acids or reduction to boronate esters, expanding the scope of reactions in which it can participate.Moreover, the presence of the chlorothiophenyl group in $name$ offers the potential for further derivatization through functional group transformations, allowing for the selective modification of the molecule for specific synthetic purposes. Overall, the strategic incorporation of 2-(4-Chlorothiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane in chemical synthesis enables efficient and controlled reactions, making it a valuable tool for organic chemists seeking to access diverse molecular architectures.