1041-01-6 | 3,5-Diiodo-L-thyronine

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$30.00	$21.00
1g	95%	in stock	$48.00	$34.00
5g	98%	in stock	$219.00	$153.00
10g	98%	in stock	$387.00	$271.00
25g	98%	in stock	$760.00	$532.00

Description

• Catalog Number: AB63944
• Chemical Name: 3,5-Diiodo-L-thyronine
• CAS Number: 1041-01-6
• Molecular Formula: C15H13I2NO4
• Molecular Weight: 525.0770
• MDL Number: MFCD00064987
• SMILES: OC(=O)[C@H](Cc1cc(I)c(c(c1)I)Oc1ccc(cc1)O)N

Computed Properties

• Complexity: 365
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 22
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 5
• XLogP3: 1.1

Upstream Synthesis Route

3,5-Diiodo-L-thyronine (DIT) is a compound that finds valuable application in chemical synthesis processes. This compound is commonly used as a precursor in the synthesis of various thyroid hormones, including triiodothyronine (T3) and thyroxine (T4). By utilizing DIT as a starting material, chemists are able to efficiently create other thyroid hormones through multi-step synthesis pathways.Additionally, 3,5-Diiodo-L-thyronine has been instrumental in the development of pharmaceuticals targeting thyroid disorders. Its unique structure and properties make it a key intermediate in the production of medications that regulate thyroid function and metabolism. Through strategic manipulation and transformation of DIT, chemists can access a diverse range of thyroid-related compounds with potential therapeutic applications.Furthermore, DIT serves as a valuable building block in the design and synthesis of novel organic molecules with potential pharmacological activities. By incorporating DIT into molecular frameworks, researchers can explore its chemical reactivity and biological effects to develop new drug candidates or probe receptor interactions. This versatility makes 3,5-Diiodo-L-thyronine a versatile tool in the field of medicinal chemistry and drug discovery.

Literature

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  The Journal of endocrinology 20120201

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