104104-50-9 | Gabazine Hydrobromide

Packsize	Purity	Availability	Price	Discounted Price
1mg	98% by HPLC	in stock	$73.00	$52.00
5mg	95%	in stock	$86.00	$60.00
10mg	95%	in stock	$129.00	$90.00
50mg	95%	in stock	$472.00	$330.00
100mg	95%	in stock	$843.00	$590.00

Description

• Catalog Number: AE09916
• Chemical Name: Gabazine Hydrobromide
• CAS Number: 104104-50-9
• Molecular Formula: C15H18BrN3O3
• Molecular Weight: 368.2257
• MDL Number: MFCD09055424
• SMILES: COc1ccc(cc1)c1ccc(=[NH2+])n(n1)CCCC(=O)O.[Br-]

Upstream Synthesis Route

Gabazine hydrobromide, also known as SR-95531, is a chemical compound commonly used in chemical synthesis as a potent and selective antagonist for γ-aminobutyric acid type A (GABA-A) receptors. This compound plays a crucial role in studying the physiological and pharmacological functions of GABA-A receptors, which are the principal inhibitory neurotransmitter receptors in the central nervous system.In chemical synthesis, Gabazine hydrobromide is often utilized to block the activity of GABA-A receptors, which are involved in regulating neuronal excitability. By selectively inhibiting these receptors, researchers can study the effects of GABAergic transmission in various biological processes and disease models. This compound is particularly valuable in elucidating the roles of GABA-A receptors in synaptic transmission, neuronal signaling, and neuropharmacology.Furthermore, Gabazine hydrobromide is essential in drug discovery and development, as it serves as a tool compound for investigating the mechanisms of action of potential GABAergic drugs and neuroactive substances. Its high affinity and specificity for GABA-A receptors make it a valuable reagent for exploring the interactions between ligands and receptor subunits, providing valuable insights into the design of novel pharmacological agents targeting the GABAergic system.